Julian Bergen Smith
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View article: E-cigarette vapor amplifies neutrophilic inflammation and proteolytic EVs in response to LPS
E-cigarette vapor amplifies neutrophilic inflammation and proteolytic EVs in response to LPS Open
Background While e-cigarette use (vaping) has increased in the last decade, its effects on airway inflammation and extracellular vesicle (EV) biology remain unclear. This study examined how long-term and acute vapor exposures influence lun…
View article: Protocol for isolating extracellular vesicles from human or mouse airway macrophages for functional assays and in vivo or in vitro experimentation
Protocol for isolating extracellular vesicles from human or mouse airway macrophages for functional assays and in vivo or in vitro experimentation Open
Macrophages are key players in host defense and lung injury, and their crosstalk with other cells dictates the course of the inflammatory response and tissue remodeling. Here, we present a protocol for isolating extracellular vesicles (EVs…