Julian Trachsel
YOU?
Author Swipe
View article: Inhibition of Escherichia coli O157:H7 Growth Through Nutrient Competition by Non-O157 E. coli Isolated from Cattle
Inhibition of Escherichia coli O157:H7 Growth Through Nutrient Competition by Non-O157 E. coli Isolated from Cattle Open
Escherichia coli O157:H7 is a major food safety concern through contamination of beef and produce. Non-antibiotic interventions to minimize O157:H7 in food animals and products are highly desired and one strategy to improve food safety is …
View article: Improving immune‐related health outcomes post‐cesarean birth with a gut microbiome‐based program: A randomized controlled trial
Improving immune‐related health outcomes post‐cesarean birth with a gut microbiome‐based program: A randomized controlled trial Open
Background Infants born via Cesarean section (C‐section) often have a distinct gut microbiome and higher risks of atopic and immune‐related conditions than vaginally delivered infants. We evaluated whether a microbiome‐based program could …
View article: Growth dynamics and protein-expression of Escherichia coli serotypes O26:H11, O111:H8 and O145:NM in the bovine rumen
Growth dynamics and protein-expression of Escherichia coli serotypes O26:H11, O111:H8 and O145:NM in the bovine rumen Open
To adapt to the ruminal environment, Shiga toxin-producing Escherichia coli (STEC) O157:H7 (O157) expresses proteins involved in survival rather than virulence. Additionally, STEC O157 strains exhibit distinct in vitro but shared in vivo s…
View article: Single-cell RNA sequencing characterization of Holstein cattle blood and milk immune cells during a chronic Staphylococcus aureus mastitis infection
Single-cell RNA sequencing characterization of Holstein cattle blood and milk immune cells during a chronic Staphylococcus aureus mastitis infection Open
View article: Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses
Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses Open
Vaccines that cross-protect across serovars of Salmonella enterica ( Salmonella ) would be a beneficial intervention against emerging and persistent Salmonella isolates of concern for the turkey industry. The 2017–2019 foodborne outbreak o…
View article: Growth dynamics and protein-expression of<i>Escherichia coli</i>serotypes O26:H11, O111:H8 and O145:NM in the bovine rumen
Growth dynamics and protein-expression of<i>Escherichia coli</i>serotypes O26:H11, O111:H8 and O145:NM in the bovine rumen Open
To adapt to the ruminal environment, Shiga toxin-producing Escherichia coli (STEC) O157:H7 (O157) expresses proteins involved in survival rather than virulence. Additionally, STEC O157 strains exhibit distinct in vitro but shared in vivo s…
View article: Tetracycline resistance gene transfer from Escherichia coli donors to Salmonella Heidelberg in chickens is impacted by the genetic context of donors
Tetracycline resistance gene transfer from Escherichia coli donors to Salmonella Heidelberg in chickens is impacted by the genetic context of donors Open
Chicken ceca are a rich source of bacteria, including zoonotic pathogens such as Salmonella enterica. The microbiota includes strains/species carrying antimicrobial resistance genes and horizontal transfer of resistance determinants betwee…
View article: Phenotypic and genomic comparison of three human outbreak and one cattle-associated Shiga toxin-producing <i>Escherichia coli</i> O157:H7
Phenotypic and genomic comparison of three human outbreak and one cattle-associated Shiga toxin-producing <i>Escherichia coli</i> O157:H7 Open
Escherichia coli O157:H7-adulterated food products are associated with disease outbreaks in humans. Although cattle feces are a source for E. coli O157:H7 contamination, it is unclear if human-associated outbreak isolates differentially co…
View article: Genomic and phenotypic characterization of multidrug-resistant Salmonella enterica serovar Reading isolates involved in a turkey-associated foodborne outbreak
Genomic and phenotypic characterization of multidrug-resistant Salmonella enterica serovar Reading isolates involved in a turkey-associated foodborne outbreak Open
Salmonella is a global bacterial foodborne pathogen associated with a variety of contaminated food products. Poultry products are a common source of Salmonella -associated foodborne illness, and an estimated 7% of human illnesses in the Un…
View article: Metabolic and genomic characterization of two novel butyrate producing Lachnospiraceae isolated from swine feces
Metabolic and genomic characterization of two novel butyrate producing Lachnospiraceae isolated from swine feces Open
Commensal bacteria from the swine gut microbiome that can be isolated have numerous potential applications in the animal production industry, including mitigation of disease, improving performance, and promoting colonization resistance to …
View article: Genomic and phenotypic comparison of two variants of multidrug-resistant Salmonella enterica serovar Heidelberg isolated during the 2015–2017 multi-state outbreak in cattle
Genomic and phenotypic comparison of two variants of multidrug-resistant Salmonella enterica serovar Heidelberg isolated during the 2015–2017 multi-state outbreak in cattle Open
Salmonella enterica subspecies enterica serovar Heidelberg ( Salmonella Heidelberg) has caused several multistate foodborne outbreaks in the United States, largely associated with the consumption of poultry. However, a 2015–2017 multidrug-…
View article: Effects of β-glucan on Salmonella enterica serovar Typhimurium swine colonization and microbiota alterations
Effects of β-glucan on Salmonella enterica serovar Typhimurium swine colonization and microbiota alterations Open
Background The 2017 Veterinary Feed Directive eliminated the use of medically important antibiotics for growth promotion of food animals; thus, alternative growth promoters are highly desirable by food animal producers to enhance animal he…
View article: Effect of dietary β-glucan on intestinal microbial diversity and Salmonella vaccine immunogenicity and efficacy in pigs
Effect of dietary β-glucan on intestinal microbial diversity and Salmonella vaccine immunogenicity and efficacy in pigs Open
Alternatives to antibiotics to improve animal performance, limit the negative impact of infectious disease, and/or reduce colonization with foodborne pathogens is a major focus of animal agricultural research. β-glucans, a generally-recogn…
View article: Phenotypic and genomic comparison of human outbreak and cattle-associated Shiga toxin-producing <i>Escherichia coli</i> O157:H7
Phenotypic and genomic comparison of human outbreak and cattle-associated Shiga toxin-producing <i>Escherichia coli</i> O157:H7 Open
Escherichia coli O157:H7 (O157)-adulterated food products, including beef and produce, are associated with disease outbreaks in humans. Although cattle feces are a source for the contamination, it is unclear if diverse O157 human-associate…
View article: Evaluation of digestively resistant or soluble fibers, short- and medium-chain fatty acids, trace minerals, and antibiotics in nonchallenged nursery pigs on performance, digestibility, and intestinal integrity
Evaluation of digestively resistant or soluble fibers, short- and medium-chain fatty acids, trace minerals, and antibiotics in nonchallenged nursery pigs on performance, digestibility, and intestinal integrity Open
Three experiments (EXP) were conducted to determine the effect of feed additives on performance, intestinal integrity, gastrointestinal volatile fatty acids (VFA), and energy and nutrient digestion in nonchallenged nursery pigs. In EXP 1, …
View article: Intestinal single-cell atlas reveals novel lymphocytes in pigs with similarities to human cells
Intestinal single-cell atlas reveals novel lymphocytes in pigs with similarities to human cells Open
Lymphocytes can heavily influence intestinal health, but resolving intestinal lymphocyte function is challenging as the intestine contains a vastly heterogeneous mixture of cells. Pigs are an advantageous biomedical model, but deeper under…
View article: Novel reusable animal model for comparative evaluation of in vivo growth and protein-expression of Escherichia coli O157 strains in the bovine rumen
Novel reusable animal model for comparative evaluation of in vivo growth and protein-expression of Escherichia coli O157 strains in the bovine rumen Open
Previously, we had demonstrated that Escherichia coli O157:H7 (O157) strain 86–24 expresses proteins involved in survival rather than virulence in vitro in rumen fluid from dairy cattle limit fed a maintenance diet. Here, we verified if th…
View article: Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch
Short Chain Fatty Acids and Bacterial Taxa Associated with Reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in Swine Fed a Diet Supplemented with Resistant Potato Starch Open
Prebiotics, such as resistant potato starch (RPS), are types of food that help to support beneficial bacteria and their activities in the intestines. Salmonella enterica serovar I 4,[5],12:i:- is a foodborne pathogen that commonly resides …
View article: Route of oxytetracycline administration differentially impacts the growth and gut microbiome of pigs co-infected with <i>Bordetella bronchiseptica</i> and <i>Pasteurella multocida</i>
Route of oxytetracycline administration differentially impacts the growth and gut microbiome of pigs co-infected with <i>Bordetella bronchiseptica</i> and <i>Pasteurella multocida</i> Open
Along with judicious antibiotic use, there is great interest in how the dose regimen of an antibiotic affects the animal gut microbiota. This study evaluated the impact of experimental respiratory infection alone or respiratory infection f…
View article: Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database
Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database Open
Background Of the > 2600 Salmonella serovars, Salmonella enterica serovar I 4,[5],12:i:- (serovar I 4,[5],12:i:-) has emerged as one of the most common causes of human salmonellosis and the most frequent multidrug-resistant (MDR; resistanc…
View article: Porcine intestinal innate lymphoid cells and lymphocyte spatial context revealed through single-cell RNA sequencing
Porcine intestinal innate lymphoid cells and lymphocyte spatial context revealed through single-cell RNA sequencing Open
Intestinal lymphocytes are crucial members of the mucosal immune system with impact over outcomes of intestinal health versus dysbiosis. Resolving intestinal lymphocyte complexity and function is a challenge, as the intestine provides cell…
View article: Additional file 9 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database
Additional file 9 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database Open
Additional file 9: Table S8. Putative transmission clusters for Salmonella enterica serovar I 4,[5],12:i:- strain sequences.
View article: Additional file 4 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database
Additional file 4 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database Open
Additional file 4: Table S3. Salmonella serovar I 4,[5],12:i:- genes in the shell genome representing gene families present at intermediate frequencies.
View article: Additional file 6 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database
Additional file 6 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database Open
Additional file 6: Table S5. GO term enrichment analysis for accessory genome cluster A.
View article: Additional file 8 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database
Additional file 8 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database Open
Additional file 8: Table S7. GO term enrichment analysis for accessory genome cluster C.
View article: Additional file 7 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database
Additional file 7 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database Open
Additional file 7: Table S6. GO term enrichment analysis for accessory genome cluster B.
View article: Additional file 2 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database
Additional file 2 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database Open
Additional file 2: Table S1. Metadata for 13,612 Salmonella serovar I 4,[5],12:i:- strain sequences from the NCBI Pathogen Detection database.
View article: Additional file 5 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database
Additional file 5 of Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database Open
Additional file 5: Table S4. Salmonella serovar I 4,[5],12:i:- genes in the cloud genome representing gene families present at low frequencies.
View article: Natural Horizontal Gene Transfer of Antimicrobial Resistance Genes in Campylobacter spp. From Turkeys and Swine
Natural Horizontal Gene Transfer of Antimicrobial Resistance Genes in Campylobacter spp. From Turkeys and Swine Open
Antibiotic-resistant Campylobacter constitutes a serious threat to public health. The clonal expansion of resistant strains and/or the horizontal spread of resistance genes to other strains and species can hinder the clinical effectiveness…
View article: Re-Emergence of Salmonellosis in Hog Farms: Outbreak and Bacteriological Characterization
Re-Emergence of Salmonellosis in Hog Farms: Outbreak and Bacteriological Characterization Open
Clinical salmonellosis has been increasing significantly in Brazil in recent years. A total of 130 outbreaks distributed among 10 swine-producing states were investigated. One representative Salmonella isolate from each outbreak was charac…