Julie Cleaver
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View article: Development and characterisation of improved unifocal primary mouse lung cancer models with metastatic potential
Development and characterisation of improved unifocal primary mouse lung cancer models with metastatic potential Open
Lung cancer is the leading cause of cancer‐related death globally. To better understand the biology of lung cancer, mouse models have been developed using either tail vein‐injected tumour cell lines or genetically modified mice. The curren…
View article: Cover Image, Volume 45, Issue 6
Cover Image, Volume 45, Issue 6 Open
The cover image is based on the article Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma by James Pittaway et al., https://doi.org/10.1002/cac2.70012 . image
View article: Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma
Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma Open
Adrenocortical carcinoma (ACC) is a rare malignancy with no widely available biomarkers and commonly presents at later stages with a bleak prognosis (1). Dysregulation of signaling pathways involved in the organogenesis and homeostasis of …
View article: Maleic anhydride derived diphosphines: adaptable chelators for receptor-targeted <sup>99m</sup>Tc, <sup>64</sup>Cu and <sup>188</sup>Re radiotracers
Maleic anhydride derived diphosphines: adaptable chelators for receptor-targeted <sup>99m</sup>Tc, <sup>64</sup>Cu and <sup>188</sup>Re radiotracers Open
Two new, versatile bis(phosphino)maleic anhydride platforms enable facile preparation of diphosphine bioconjugates that can be simply radiolabelled with 99m Tc for SPECT imaging, 64 Cu for PET imaging and 188 Re for systemic radiotherapy.
View article: Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma
Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma Open
Disruption of processes involved in tissue development and homeostatic self-renewal is increasingly implicated in cancer initiation, progression, and recurrence. The adrenal cortex is a dynamic tissue that undergoes life-long turnover. Her…
View article: Receptor-Targeted Peptide Conjugates Based on Diphosphines Enable Preparation of<sup>99m</sup>Tc and<sup>188</sup>Re Theranostic Agents for Prostate Cancer
Receptor-Targeted Peptide Conjugates Based on Diphosphines Enable Preparation of<sup>99m</sup>Tc and<sup>188</sup>Re Theranostic Agents for Prostate Cancer Open
Benchtop 99Mo/99mTc and 188W/188Re generators enable economical production of molecular theranostic 99mTc and 188Re radiopharmaceuticals, provided that simple, kit-based chemistry exists to radiolabel targeting vectors with these radionucl…