Julien Cicero
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View article: Cellular metabolic state controls mitochondrial RNA kinetics
Cellular metabolic state controls mitochondrial RNA kinetics Open
Human mitochondrial genome encodes essential genes for the oxidative phosphorylation (OXPHOS) complexes. These genes must be transcribed and translated in coordination with nuclear-encoded OXPHOS components to ensure correct stoichiometry …
View article: Mitochondria- and ER-associated actin are required for mitochondrial fusion
Mitochondria- and ER-associated actin are required for mitochondrial fusion Open
View article: Beyond static snapshots: Mitochondria in action
Beyond static snapshots: Mitochondria in action Open
Mitochondria are dynamic organelles essential for cellular homeostasis, undergoing continuous fission and fusion processes that regulate their morphology, distribution, and function. Disruptions in these dynamics are linked to numerous dis…
View article: Single-Cell Mechanical Characterization by a Mems Robot During Subcellular Visualization
Single-Cell Mechanical Characterization by a Mems Robot During Subcellular Visualization Open
View article: ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells
ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells Open
View article: Influence of EGF and pro-NGF on EGFR/SORTILIN interaction and clinical impact in head and neck squamous cell carcinoma
Influence of EGF and pro-NGF on EGFR/SORTILIN interaction and clinical impact in head and neck squamous cell carcinoma Open
Head and Neck Squamous Cell Carcinoma (HNSCC) remains a cancer with a poor prognosis, with a 5-year survival rate of less than 50%. Although epidermal growth factor receptor (EGFR) is almost always overexpressed, targeted anti-EGFR therapi…
View article: Mitochondria- and ER-associated actin are required for mitochondrial fusion
Mitochondria- and ER-associated actin are required for mitochondrial fusion Open
Mitochondria play a crucial role in the regulation of cellular metabolism and signalling. Mitochondrial activity is modulated by the processes of mitochondrial fission and fusion, which are required to properly balance respiratory and meta…
View article: TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells
TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells Open
Emerging evidence indicates that the TRPM8 channel plays an important role in prostate cancer (PCa) progression, by impairing the motility of these cancer cells. Here, we reveal a novel facet of PCa motility control via direct protein-prot…
View article: Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells
Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells Open
View article: Loss of Polycomb Repressive Complex 2 Function Alters Digestive Organ Homeostasis and Neuronal Differentiation in Zebrafish
Loss of Polycomb Repressive Complex 2 Function Alters Digestive Organ Homeostasis and Neuronal Differentiation in Zebrafish Open
Polycomb repressive complex 2 (PRC2) mediates histone H3K27me3 methylation and the stable transcriptional repression of a number of gene expression programs involved in the control of cellular identity during development and differentiatio…