Julien Novarino YOU? Author Swipe

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The tumor necrosis superfamily member 4-1BBL expressed by tumor cells prevents exhaustion of CD8 T cells in a humanized mouse model of papillary renal cell carcinoma Open

Marie Fornier, Julien Novarino, Marie Naturel, Marylou Panouillot, Marie‐Caroline Dieu‐Nosjean , et al. · 2025

Summary Background 4-1BB (CD137), a member of the TNF receptor superfamily, is a critical co-stimulatory receptor for CD8⁺ T cell activation and regulatory T cell (Treg) expansion. While its ligand 4-1BBL is typically expressed by professi…

Les enképhalines produites par les lymphocytes T régulateurs modulent la douleur chez la souris Open

Julien Novarino, Wangtianrui Li, Gilles Marodon · 2025

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Author response: Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice Open

Nicolas Aubert, Madeleine Purcarea, Julien Novarino, Julien Schopp, Alexis Audibert , et al. · 2024

Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice Open

Nicolas Aubert, Madeleine Purcarea, Julien Novarino, Julien Schopp, Alexis Audibert , et al. · 2024

CD4 + CD25 + Foxp3 + regulatory T cells (Treg) have been implicated in pain modulation in various inflammatory conditions. However, whether Treg cells hamper pain at steady state and by which mechanism is still unclear. From a meta-analysi…

Author response: Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice Open

Nicolas Aubert, Madeleine Purcarea, Julien Novarino, Julien Schopp, Alexis Audibert , et al. · 2024

CD4+CD25+Foxp3+ regulatory T cells (Treg) have been implicated in pain modulation in various inflammatory conditions. However, whether Treg cells hamper pain at steady state and by which mechanism is still unclear. From a meta-analysis of …

Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice Open

Nicolas Aubert, Madeleine Purcarea, Julien Novarino, Julien Schopp, Alexis Audibert , et al. · 2024

CD4+CD25+Foxp3+ regulatory T cells (Treg) have been implicated in pain modulation in various inflammatory conditions. However, whether Treg cells hamper pain at steady state and by which mechanism is still unclear. From a meta-analysis of …

Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice Open

Nicolas Aubert, Madeleine Purcarea, Julien Novarino, Julien Schopp, Alexis Audibert , et al. · 2024

CD4 + CD25 + Foxp3 + regulatory T cells (Treg) have been implicated in pain modulation in various inflammatory conditions. However, whether Treg cells hamper pain at steady state and by which mechanism is still unclear. From a meta-analysi…

Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice Open

Nicolas Aubert, Madeleine Purcarea, Julien Novarino, Julien Schopp, Alexis Audibert , et al. · 2023

CD4 + CD25 + Foxp3 + regulatory T cells (Treg) have been implicated in pain modulation in various inflammatory conditions. However, whether Treg cells hamper pain at steady state and by which mechanism is still unclear. From a meta-analysi…

Les lymphocytes T folliculaires auxiliaires et les lymphocytes T régulateurs, un partenariat surprenant dans la réponse humorale Open

Julien Novarino · 2023

An effective vaccine response results in the long-lasting production of antibodies (Ab) of high affinity for the characteristic antigen of a pathogen or a toxin against those who want to protect us. To produce these Abs, B lymphocytes must…

Rituximab tunes desmoglein-3-specific follicular T cells in patients with pemphigus vulgaris Open

V. Hébert, Julien Novarino, Maud Maho‐Vaillant, Corine Pérals, Cyrielle Bories , et al. · 2023

Background : Pemphigus vulgaris (PV) is characterized by pathogenic auto-antibodies targeting interkeratinocytes desmoglein (Dsg) 1 and 3, and by the HLA-DRB1-0402 predisposition allele. Treatment using rituximab (RTX) combined with short-…

Ageing of T-dependent B cell responses Open

Fanny Martinez, Julien Novarino, José Enrique Mejía, Nicolas Fazilleau, Meryem Aloulou · 2021

Evidence for tmTNF reverse signaling in vivo: Implications for an arginase-1-mediated therapeutic effect of TNF inhibitors during inflammation Open

Katy Diallo, Numa Simons, Souraya Sayegh, Michel Baron, Yannick Degboé , et al. · 2021

Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ Open

Louise M. C. Webb, Sigrid Fra-Bidó, Silvia Innocentin, Louise S. Matheson, Noudjoud Attaf , et al. · 2021

Ageing profoundly changes our immune system and is thought to be a driving factor in the morbidity and mortality associated with infectious disease in older people. We have previously shown that the impaired immunity to vaccination that oc…

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