Julien Riou
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View article: Determinants and spatio-temporal structure of variability in wastewater SARS-CoV-2 viral load measurements in Switzerland: Key insights for future surveillance efforts
Determinants and spatio-temporal structure of variability in wastewater SARS-CoV-2 viral load measurements in Switzerland: Key insights for future surveillance efforts Open
Background: Wastewater-based surveillance (WBS) has emerged as a valuable tool for monitoring the circulation of infectious pathogens in the population, offering a complement to classical surveillance methods. However, the interpretation o…
View article: Ensemble Bayesian modelling with dynamic population to estimate excess deaths due to extreme temperatures
Ensemble Bayesian modelling with dynamic population to estimate excess deaths due to extreme temperatures Open
Extreme heat has been linked to increased mortality. Monitoring the mortality burden attributable to extreme heat is crucial to inform policies, such as heat warnings, and prevent heat-related deaths. In this study, we evaluate excess mort…
View article: ICD-10 code embedding for patient matching: a first step towards applications in causal inference from hospital discharge data
ICD-10 code embedding for patient matching: a first step towards applications in causal inference from hospital discharge data Open
We present WEMatch, a Word2vec Enhanced ICD-10 Matching algorithm, for patient matching based on ICD-10 codes and make a first step toward evaluating its potential use in causal inference contexts by comparing it to several propensity scor…
View article: Human exposure to persistent organic pollutants in Switzerland: The role of diet, age, smoking, and body composition
Human exposure to persistent organic pollutants in Switzerland: The role of diet, age, smoking, and body composition Open
Persistent organic pollutants (POPs), including polychlorinated dibenzo-p-dioxin/dibenzofuran (PCDD/Fs) and polychlorinated biphenyls (PCBs), are widespread environmental contaminants that bioaccumulate in human, primarily through dietary …
View article: Excess mortality attributable to the 2025 Iberian Peninsula blackout
Excess mortality attributable to the 2025 Iberian Peninsula blackout Open
On 28 April 2025, a widespread power outage affected mainland Portugal and Spain for around ten hours, causing major disruptions and eight reported deaths. Health impacts of blackouts range from direct effects, like fires and medical equip…
View article: Post-sampling degradation of viral RNA in wastewater impacts the quality of PCR-based concentration estimates
Post-sampling degradation of viral RNA in wastewater impacts the quality of PCR-based concentration estimates Open
Successful wastewater-based infectious disease surveillance programs depend on regular, reliable molecular detection of nucleic acids in municipal wastewater systems. This process is challenged by the gradual degradation of the viral conte…
View article: Machine learning-based short-term forecasting of COVID-19 hospital admissions using routine hospital patient data
Machine learning-based short-term forecasting of COVID-19 hospital admissions using routine hospital patient data Open
During the COVID-19 pandemic, the field of infectious disease modeling advanced rapidly, with forecasting tools developed to track trends in transmission dynamics and anticipate potential shortages of critical resources such as hospital ca…
View article: Determinants and spatio-temporal structure of variability in wastewater SARS-CoV-2 viral load measurements in Switzerland: key insights for future surveillance efforts
Determinants and spatio-temporal structure of variability in wastewater SARS-CoV-2 viral load measurements in Switzerland: key insights for future surveillance efforts Open
Background: Wastewater-based surveillance (WBS) has emerged as a valuable tool for monitoring the circulation of infectious pathogens in the population, offering a complement to classical surveillance methods. However, the interpretation o…
View article: Review 1: "The Global Burden of Chikungunya Virus and the Potential Benefit of Vaccines"
Review 1: "The Global Burden of Chikungunya Virus and the Potential Benefit of Vaccines" Open
View article: Review of "The Global Burden of Chikungunya Virus and the Potential Benefit of Vaccines"
Review of "The Global Burden of Chikungunya Virus and the Potential Benefit of Vaccines" Open
View article: Estimating Re and overdispersion in secondary cases from the size of identical sequence clusters of SARS-CoV-2
Estimating Re and overdispersion in secondary cases from the size of identical sequence clusters of SARS-CoV-2 Open
The wealth of genomic data that was generated during the COVID-19 pandemic provides an exceptional opportunity to obtain information on the transmission of SARS-CoV-2. Specifically, there is great interest to better understand how the effe…
View article: Serum biomonitoring of per- and polyfluoroalkyl substances (PFASs) in the adult population of Switzerland: Results from the pilot phase of the Swiss health study
Serum biomonitoring of per- and polyfluoroalkyl substances (PFASs) in the adult population of Switzerland: Results from the pilot phase of the Swiss health study Open
Monitoring human exposure to per- and polyfluoroalkyl substances (PFASs) is of significant public health relevance, given the documented associations between PFAS exposure and a range of adverse health outcomes. This study aimed to provide…
View article: Why gender and sex matter in infectious disease modelling: A conceptual framework
Why gender and sex matter in infectious disease modelling: A conceptual framework Open
View article: Diet, Lifestyle, and Sociodemographic Influences on Serum Concentration of PFASs: Insights from Human Biomonitoring in Switzerland
Diet, Lifestyle, and Sociodemographic Influences on Serum Concentration of PFASs: Insights from Human Biomonitoring in Switzerland Open
View article: Patterns and drivers of excess mortality during the COVID-19 pandemic in 13 Western European countries
Patterns and drivers of excess mortality during the COVID-19 pandemic in 13 Western European countries Open
These results suggest the benefit of early implementation of NPIs and swift rollout of vaccines to the most vulnerable. Further analyses are required at a more granular level to better understand how these factors impacted excess mortality…
View article: Estimating<i>R<sub>e</sub></i>and overdispersion in secondary cases from the size of identical sequence clusters of SARS-CoV-2
Estimating<i>R<sub>e</sub></i>and overdispersion in secondary cases from the size of identical sequence clusters of SARS-CoV-2 Open
The wealth of genomic data that was generated during the COVID-19 pandemic provides an exceptional opportunity to obtain information on the transmission of SARS-CoV-2. Specifically, there is great interest to better understand how the effe…
View article: Gender/Sex Disparities in the COVID-19 Cascade From Testing to Mortality: An Intersectional Analysis of Swiss Surveillance Data
Gender/Sex Disparities in the COVID-19 Cascade From Testing to Mortality: An Intersectional Analysis of Swiss Surveillance Data Open
Objectives: This study investigates gender and sex disparities in COVID-19 epidemiology in the Canton of Vaud, Switzerland, focusing on the interplay with socioeconomic position (SEP) and age. Methods: We analyzed COVID-19 surveillance dat…
View article: Bayesian workflow for time-varying transmission in stratified compartmental infectious disease transmission models
Bayesian workflow for time-varying transmission in stratified compartmental infectious disease transmission models Open
Compartmental models that describe infectious disease transmission across subpopulations are central for assessing the impact of non-pharmaceutical interventions, behavioral changes and seasonal effects on the spread of respiratory infecti…
View article: Health of singleton neonates in Switzerland through time and crises: a cross-sectional study at the population level, 2007-2022
Health of singleton neonates in Switzerland through time and crises: a cross-sectional study at the population level, 2007-2022 Open
View article: Gender/Sex Disparities in the COVID-19 Cascade from Testing to Mortality: An Intersectional Analysis of Swiss Surveillance Data
Gender/Sex Disparities in the COVID-19 Cascade from Testing to Mortality: An Intersectional Analysis of Swiss Surveillance Data Open
Objectives This study investigates gender and sex disparities in COVID-19 epidemiology in the Canton of Vaud, Switzerland, focusing on the interplay with socioeconomic position (SEP) and age. Methods We analyzed COVID-19 surveillance data …
View article: Area-level excess mortality in times of COVID-19 in Switzerland: geographical, socioeconomic and political determinants
Area-level excess mortality in times of COVID-19 in Switzerland: geographical, socioeconomic and political determinants Open
The coronavirus disease 2019 (COVID-19)-related excess mortality in Switzerland is well documented, but no study examined mortality at the small-area level. We analysed excess mortality in 2020 for 2141 Swiss municipalities using a Bayesia…
View article: Surveillance of SARS-CoV-2 prevalence from repeated pooled testing: application to Swiss routine data
Surveillance of SARS-CoV-2 prevalence from repeated pooled testing: application to Swiss routine data Open
Surveillance of SARS-CoV-2 through reported positive RT-PCR tests is biased due to non-random testing. Prevalence estimation in population-based samples corrects for this bias. Within this context, the pooled testing design offers many adv…
View article: Subregional Excess Mortality and Excess Mortality Temperature Thresholds During Summer 2022: A Population-Based Analysis in Switzerland
Subregional Excess Mortality and Excess Mortality Temperature Thresholds During Summer 2022: A Population-Based Analysis in Switzerland Open
View article: Bayesian workflow for time-varying transmission in stratified compartmental infectious disease transmission models
Bayesian workflow for time-varying transmission in stratified compartmental infectious disease transmission models Open
Compartmental models that describe infectious disease transmission across subpopulations are central for assessing the impact of non-pharmaceutical interventions, behavioral changes and seasonal effects on the spread of respiratory infecti…
View article: Bayesian ensemble modelling to monitor excess deaths during summer 2022 in Switzerland
Bayesian ensemble modelling to monitor excess deaths during summer 2022 in Switzerland Open
Switzerland experienced one of the warmest summers during 2022. Extreme heat has been linked to increased mortality. Monitoring the mortality burden attributable to extreme heat is crucial to inform policies, such as heat warnings, and pre…
View article: Socio-demographic characteristics associated with COVID-19 vaccination uptake in Switzerland: longitudinal analysis of the CoMix study
Socio-demographic characteristics associated with COVID-19 vaccination uptake in Switzerland: longitudinal analysis of the CoMix study Open
View article: COVID‐19 among adults living with HIV: correlates of mortality among public sector healthcare users in Western Cape, South Africa
COVID‐19 among adults living with HIV: correlates of mortality among public sector healthcare users in Western Cape, South Africa Open
Introduction While a large proportion of people with HIV (PWH) have experienced SARS‐CoV‐2 infections, there is uncertainty about the role of HIV disease severity on COVID‐19 outcomes, especially in lower‐income settings. We studied the as…
View article: Projecting the development of antimicrobial resistance in Neisseria gonorrhoeae from antimicrobial surveillance data: a mathematical modelling study
Projecting the development of antimicrobial resistance in Neisseria gonorrhoeae from antimicrobial surveillance data: a mathematical modelling study Open
View article: Socio-demographic characteristics associated with COVID-19 vaccination uptake in Switzerland: longitudinal analysis of the CoMix study
Socio-demographic characteristics associated with COVID-19 vaccination uptake in Switzerland: longitudinal analysis of the CoMix study Open
Background Vaccination is an effective strategy to reduce morbidity and mortality from coronavirus disease 2019 (COVID-19). However, the uptake of COVID-19 vaccination has varied across and within countries. Switzerland has had lower level…
View article: Direct and indirect effects of the COVID-19 pandemic on mortality in Switzerland
Direct and indirect effects of the COVID-19 pandemic on mortality in Switzerland Open