Juliette Ferrant
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View article: Myeloid landscape profiling identifies DLBCL-specific suppressive macrophages colocalized with blood endothelial cells
Myeloid landscape profiling identifies DLBCL-specific suppressive macrophages colocalized with blood endothelial cells Open
Diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) are the two most common B-cell lymphomas and are characterized by a dynamic crosstalk between tumor B cells and a heterogeneous tumor-supportive microenvironment, including…
View article: POS0995 SKIN MACROPHAGE SUBTYPES AND IMPACT OF TOFACITINIB IN EARLY DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS: RESULTS FROM COMBINED SINGLE-CELL ANALYSES OF AN OBSERVATIONAL DATA SET AND A PHASE I/II RANDOMIZED CONTROLLED TRIAL
POS0995 SKIN MACROPHAGE SUBTYPES AND IMPACT OF TOFACITINIB IN EARLY DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS: RESULTS FROM COMBINED SINGLE-CELL ANALYSES OF AN OBSERVATIONAL DATA SET AND A PHASE I/II RANDOMIZED CONTROLLED TRIAL Open
View article: Hypothermic machine perfusion in uterus transplantation in a porcine model: A proof of concept and the first results in graft preservation
Hypothermic machine perfusion in uterus transplantation in a porcine model: A proof of concept and the first results in graft preservation Open
Introduction Graft optimization is a necessity in order to develop uterus transplantation from brain‐dead donors, as a complement to living donors, as these grafts are rare and the last organs retrieved in multiple organ donation. The aim …
View article: Blood immunophenotyping of multiple sclerosis patients at diagnosis identifies a classical monocyte subset associated to disease evolution
Blood immunophenotyping of multiple sclerosis patients at diagnosis identifies a classical monocyte subset associated to disease evolution Open
Introduction Myeloid cells trafficking from the periphery to the central nervous system are key players in multiple sclerosis (MS) through antigen presentation, cytokine secretion and repair processes. Methods Combination of mass cytometry…
View article: Pulmonary and systemic effects of inhaled crystalline silica in the HOCl-induced mouse model of systemic sclerosis: An experimental model of Erasmus syndrome.
Pulmonary and systemic effects of inhaled crystalline silica in the HOCl-induced mouse model of systemic sclerosis: An experimental model of Erasmus syndrome. Open
View article: Phenotypic and proteomic analysis of plasma extracellular vesicles highlights them as potential biomarkers of primary Sjögren syndrome
Phenotypic and proteomic analysis of plasma extracellular vesicles highlights them as potential biomarkers of primary Sjögren syndrome Open
Sjögren syndrome (SjS) is an autoimmune disease characterized by the destruction of the exocrine gland epithelia, causing a dryness of mucosa called sicca symptoms, and whose main life-threatening complication is lymphoma. There is a need …
View article: Demultiplexing Ig repertoires by parallel mRNA/DNA sequencing shows major differential alterations in severe COVID-19
Demultiplexing Ig repertoires by parallel mRNA/DNA sequencing shows major differential alterations in severe COVID-19 Open
To understand the fine differential elements that can lead to or prevent acute respiratory distress syndrome (ARDS) in COVID-19 patients, it is crucial to investigate the immune response architecture. We herein dissected the multiple layer…
View article: Single-Cell Profiling Identifies Clinically Relevant Interactions Between Tumor Associated Macrophages and Blood Endothelial Cells in Diffuse Large B Cell Lymphoma
Single-Cell Profiling Identifies Clinically Relevant Interactions Between Tumor Associated Macrophages and Blood Endothelial Cells in Diffuse Large B Cell Lymphoma Open
View article: Caractérisation des macrophages de lymphome B : hétérogénéité et dialogue avec la niche stromale et endothéliale
Caractérisation des macrophages de lymphome B : hétérogénéité et dialogue avec la niche stromale et endothéliale Open
Diffuse large B cell lymphoma (DLBCL) and follicular lymphoma (FL) are the 2 most common aggressive and indolent lymphomas. The tumor microenvironment (TME), both immune and non-immune, plays a key supportive role in these diseases. Althou…
View article: Single-cell profiling identifies clinically relevant interactions between tumor associated macrophages and blood endothelial cells in diffuse large B cell lymphoma
Single-cell profiling identifies clinically relevant interactions between tumor associated macrophages and blood endothelial cells in diffuse large B cell lymphoma Open
Summary Diffuse large B cell lymphoma (DLBCL) and follicular lymphoma (FL) are the two most common B-cell lymphomas and are characterized by a dynamic crosstalk between tumor B cells and a heterogeneous tumor-supportive microenvironment, i…
View article: Histological Subtypes Drive Distinct Prognostic Immune Signatures in Classical Hodgkin Lymphoma
Histological Subtypes Drive Distinct Prognostic Immune Signatures in Classical Hodgkin Lymphoma Open
Despite the success of standard front-line chemotherapy, 20% of classical Hodgkin lymphoma (cHL) patients still relapse or have refractory disease (r/r), and a subset of them die due to disease progression. There is a critical lack of pred…
View article: Demultiplexing Ig Repertoires by Parallel mRNA/DNA Sequencing Shows Major Differential Alterations in Severe COVID-19
Demultiplexing Ig Repertoires by Parallel mRNA/DNA Sequencing Shows Major Differential Alterations in Severe COVID-19 Open
View article: Nonclassical Monocytes Are Prone to Migrate Into Tumor in Diffuse Large B-Cell Lymphoma
Nonclassical Monocytes Are Prone to Migrate Into Tumor in Diffuse Large B-Cell Lymphoma Open
Absolute count of circulating monocytes has been proposed as an independent prognostic factor in diffuse large B-cell lymphoma (DLBCL). However, monocyte nomenclature includes various subsets with pro-, anti-inflammatory, or suppressive fu…
View article: Comparative immune profiling of acute respiratory distress syndrome patients with or without SARS-CoV-2 infection
Comparative immune profiling of acute respiratory distress syndrome patients with or without SARS-CoV-2 infection Open
View article: Mass Cytometry Identifies Expansion of T-bet+ B Cells and CD206+ Monocytes in Early Multiple Sclerosis
Mass Cytometry Identifies Expansion of T-bet+ B Cells and CD206+ Monocytes in Early Multiple Sclerosis Open
Multiple sclerosis (MS) is an immune-driven demyelinating disease of the central nervous system. Immune cell features are particularly promising as predictive biomarkers due to their central role in the pathogenesis but also as drug target…
View article: Nonclassical monocytes are prone to migrate into tumor in diffuse large B-cell lymphoma
Nonclassical monocytes are prone to migrate into tumor in diffuse large B-cell lymphoma Open
Absolute count of circulating monocytes has been proposed as an independent prognostic factor in diffuse large B-cell lymphoma (DLBCL). However, monocyte nomenclature includes various subsets with pro-, anti-inflammatory, or suppressive fu…
View article: Circulating Myeloid Regulatory Cells: Promising Biomarkers in B-Cell Lymphomas
Circulating Myeloid Regulatory Cells: Promising Biomarkers in B-Cell Lymphomas Open
The monocyte/macrophage lineage has been shown to be involved in the promotion of a protumoral tumor microenvironment and resistance to treatment in B cell lymphomas. However, it is still poorly described at the single cell level, and tiss…
View article: Mass cytometry and artificial intelligence define CD169 as a specific marker of SARS-CoV2-induced acute respiratory distress syndrome
Mass cytometry and artificial intelligence define CD169 as a specific marker of SARS-CoV2-induced acute respiratory distress syndrome Open
Acute respiratory distress syndrome (ARDS) is the main complication of COVID-19, requiring admission to Intensive Care Unit (ICU). Despite recent immune profiling of COVID-19 patients, to what extent COVID-19-associated ARDS specifically d…
View article: Mass Cytometry and Artificial Intelligence Define CD169 as a Marker of SARS-CoV2-Induced Acute Respiratory Distress Syndrome
Mass Cytometry and Artificial Intelligence Define CD169 as a Marker of SARS-CoV2-Induced Acute Respiratory Distress Syndrome Open