Juliette Patrier
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View article: Treatment of positive catheter tip culture without bloodstream infections in critically ill patients. A case-cohort study from the OUTCOMEREA network
Treatment of positive catheter tip culture without bloodstream infections in critically ill patients. A case-cohort study from the OUTCOMEREA network Open
View article: Healthcare-associated infections in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study
Healthcare-associated infections in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study Open
View article: Assessment of Bacterial Digestive Translocations by Metagenomic Sequencing in Sars-Cov-2 Viremic Patients Hospitalized in Intensive Care Units
Assessment of Bacterial Digestive Translocations by Metagenomic Sequencing in Sars-Cov-2 Viremic Patients Hospitalized in Intensive Care Units Open
View article: Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS
Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS Open
Importance Prone positioning may improve outcomes in patients with severe acute respiratory distress syndrome (ARDS), but it is unknown whether prone positioning improves clinical outcomes among patients with ARDS who are undergoing venove…
View article: Non-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP) in patients with acute exacerbation of COPD: From the French OUTCOMEREA cohort
Non-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP) in patients with acute exacerbation of COPD: From the French OUTCOMEREA cohort Open
View article: Which severe COVID-19 patients could benefit from high dose dexamethasone? A Bayesian post-hoc reanalysis of the COVIDICUS randomized clinical trial
Which severe COVID-19 patients could benefit from high dose dexamethasone? A Bayesian post-hoc reanalysis of the COVIDICUS randomized clinical trial Open
View article: Cefiderocol Treatment for Severe Infections due to Difficult-to-Treat-Resistant Non-Fermentative Gram-Negative Bacilli in ICU Patients: A Case Series and Narrative Literature Review
Cefiderocol Treatment for Severe Infections due to Difficult-to-Treat-Resistant Non-Fermentative Gram-Negative Bacilli in ICU Patients: A Case Series and Narrative Literature Review Open
Cefiderocol (FDC) is a siderophore cephalosporin now recognized as a new weapon in the treatment of difficult-to-treat-resistant (DTR) Gram-negative pathogens, including carbapenemase-producing enterobacterales and non-fermentative Gram-ne…
View article: A Simplified Electroencephalography Montage and Interpretation for Evaluation of Comatose Patients in the ICU
A Simplified Electroencephalography Montage and Interpretation for Evaluation of Comatose Patients in the ICU Open
OBJECTIVES: Electroencephalography (EEG) is one of the main tools for diagnosis and prognostication of encephalopathy. Our two objectives were to assess: 1) the reliability of intensivists’ interpretations (one trained intensivist and none…
View article: Oropharyngeal and intestinal concentrations of opportunistic pathogens are independently associated with death of SARS-CoV-2 critically ill adults
Oropharyngeal and intestinal concentrations of opportunistic pathogens are independently associated with death of SARS-CoV-2 critically ill adults Open
View article: Augmented renal clearance in the ICU: estimation, incidence, risk factors and consequences—a retrospective observational study
Augmented renal clearance in the ICU: estimation, incidence, risk factors and consequences—a retrospective observational study Open
View article: Mid-Regional Pro-Adrenomedullin as a Prognostic Factor for Severe COVID-19 ARDS
Mid-Regional Pro-Adrenomedullin as a Prognostic Factor for Severe COVID-19 ARDS Open
Mid-regional proadrenomedullin (MR-proADM) protects against endothelial permeability and has been associated with prognosis in bacterial sepsis. As endothelial dysfunction is central in the pathophysiology of severe SARS-CoV-2 infection, w…
View article: Bleeding and thrombotic events in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study
Bleeding and thrombotic events in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study Open
View article: High-Dose Dexamethasone and Oxygen Support Strategies in Intensive Care Unit Patients With Severe COVID-19 Acute Hypoxemic Respiratory Failure
High-Dose Dexamethasone and Oxygen Support Strategies in Intensive Care Unit Patients With Severe COVID-19 Acute Hypoxemic Respiratory Failure Open
ClinicalTrials.gov Identifier: NCT04344730; EudraCT: 2020-001457-43.
View article: The role of the microbiota in the management of intensive care patients
The role of the microbiota in the management of intensive care patients Open
View article: Tracheostomy in COVID-19 acute respiratory distress syndrome patients and follow-up: A parisian bicentric retrospective cohort
Tracheostomy in COVID-19 acute respiratory distress syndrome patients and follow-up: A parisian bicentric retrospective cohort Open
Background Tracheostomy has been proposed as an option to help organize the healthcare system to face the unprecedented number of patients hospitalized for a COVID-19-related acute respiratory distress syndrome (ARDS) in intensive care uni…
View article: HSV-1 reactivation is associated with an increased risk of mortality and pneumonia in critically ill COVID-19 patients
HSV-1 reactivation is associated with an increased risk of mortality and pneumonia in critically ill COVID-19 patients Open
Background Data in the literature about HSV reactivation in COVID-19 patients are scarce, and the association between HSV-1 reactivation and mortality remains to be determined. Our objectives were to evaluate the impact of Herpes simplex v…
View article: Combined use of a broad-panel respiratory multiplex PCR and procalcitonin to reduce duration of antibiotics exposure in patients with severe community-acquired pneumonia (MULTI-CAP): a multicentre, parallel-group, open-label, individual randomised trial conducted in French intensive care units
Combined use of a broad-panel respiratory multiplex PCR and procalcitonin to reduce duration of antibiotics exposure in patients with severe community-acquired pneumonia (MULTI-CAP): a multicentre, parallel-group, open-label, individual randomised trial conducted in French intensive care units Open
Introduction At the time of the worrying emergence and spread of bacterial resistance, reducing the selection pressure by reducing the exposure to antibiotics in patients with community-acquired pneumonia (CAP) is a public health issue. In…
View article: Two original observations concerning bacterial infections in COVID-19 patients hospitalized in intensive care units during the first wave of the epidemic in France
Two original observations concerning bacterial infections in COVID-19 patients hospitalized in intensive care units during the first wave of the epidemic in France Open
Among 197 COVID-19 patients hospitalized in ICU, 88 (44.7%) experienced at least one bacterial infection, with pneumonia (39.1%) and bloodstream infections (15,7%) being the most frequent. Unusual findings include frequent suspicion of bac…
View article: Impact of rapid multiplex PCR on management of antibiotic therapy in COVID-19-positive patients hospitalized in intensive care unit
Impact of rapid multiplex PCR on management of antibiotic therapy in COVID-19-positive patients hospitalized in intensive care unit Open
View article: Two original observations concerning bacterial infections in COVID-19 patients hospitalized in intensive care units during the first wave of the epidemic in France
Two original observations concerning bacterial infections in COVID-19 patients hospitalized in intensive care units during the first wave of the epidemic in France Open
Among 197 COVID-19 patients hospitalized in ICU, 88 (44.7%) experienced at least one bacterial infection, with pneumonia (39.1%) and bloodstream infections (15,7%) being the most frequent. Unusual findings include frequent suspicion of bac…
View article: Burden of pneumococcal pneumonia requiring ICU admission in France: 1-year prognosis, resources use, and costs
Burden of pneumococcal pneumonia requiring ICU admission in France: 1-year prognosis, resources use, and costs Open
View article: Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (HIV-VIR study)
Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (HIV-VIR study) Open
View article: Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Detection in Blood of Critically Ill Patients
Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Detection in Blood of Critically Ill Patients Open
To the Editor-Data on detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA in the blood of patients with coronavirus disease 2019 (COVID-19) are scarce [1][2][3].The recently published article by Veyer et al …
View article: Immune Alterations in a Patient with SARS-CoV-2-Related Acute Respiratory Distress Syndrome
Immune Alterations in a Patient with SARS-CoV-2-Related Acute Respiratory Distress Syndrome Open
View article: Caractéristiques cliniques et paracliniques de 4 patients confirmés à COVID-19
Caractéristiques cliniques et paracliniques de 4 patients confirmés à COVID-19 Open
View article: Case report study of the first five COVID-19 patients treated with remdesivir in France
Case report study of the first five COVID-19 patients treated with remdesivir in France Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been identified as the virus responsible for the coronavirus disease 2019 (COVID-19) outbreak worldwide. Data on treatment are scare and parallels have been made between SARS…
View article: Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia
Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia Open
Background Early appropriate antibiotic therapy reduces morbidity and mortality of severe pneumonia. However, the emergence of bacterial resistance requires the earliest use of antibiotics with the narrowest possible spectrum. The Unyvero …
View article: Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia
Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia Open
Background: Early appropriate antibiotic therapy reduces morbidity and mortality of severe pneumonia. However, the emergence of bacterial resistance requires the earliest use of antibiotics with the narrowest possible spectrum. The Unyvero…
View article: Pharmacokinetics of lopinavir/ritonavir oral solution to treat COVID-19 in mechanically ventilated ICU patients
Pharmacokinetics of lopinavir/ritonavir oral solution to treat COVID-19 in mechanically ventilated ICU patients Open
Background The combination lopinavir/ritonavir is recommended to treat HIV-infected patients at the dose regimen of 400/100 mg q12h, oral route. The usual lopinavir trough plasma concentrations are 3000–8000 ng/mL. A trend towards a 28 day…
View article: Immune alterations during SARS-CoV-2-related acute respiratory distress syndrome
Immune alterations during SARS-CoV-2-related acute respiratory distress syndrome Open
We report a longitudinal analysis of the immune response associated with a fatal case of COVID-19. This patient exhibited a rapid evolution towards multiorgan failure. SARS-CoV-2 was detected in multiple nasopharyngeal, blood, and pleural …