Junichi Arai
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View article: Clinical significance of para-aortic lymph node metastasis for prognosis in patients with pancreaticobiliary cancer who underwent radical surgical resections
Clinical significance of para-aortic lymph node metastasis for prognosis in patients with pancreaticobiliary cancer who underwent radical surgical resections Open
Based on these findings, radical resection may be considered for PC patients with isolated PALN metastases only in the absence of additional adverse prognostic factors. Prospective clinical trials are warranted to further refine the criter…
View article: Anti-tumor Effects of Erlotinib<i>via</i>Thymidylate Synthase Down-regulation in Pancreatic Cancer Cells
Anti-tumor Effects of Erlotinib<i>via</i>Thymidylate Synthase Down-regulation in Pancreatic Cancer Cells Open
Erlotinib could have a synergistic anti-tumor effect when combined with gemcitabine via down-regulation of TS expression.
View article: Laparoscopic Distal Gastrectomy for Duodenal Adenocarcinoma Located in a Duodenal Bulb Diverticulum: Report of a Rare Case
Laparoscopic Distal Gastrectomy for Duodenal Adenocarcinoma Located in a Duodenal Bulb Diverticulum: Report of a Rare Case Open
We report here a rare case of an adenocarcinoma arising within a duodenal bulb diverticulum. We successfully performed a laparoscopic distal gastrectomy, this procedure being considered the optimal surgical approach for this patient.
View article: Clinical Significance of Para-Aortic Node Metastasis for Prognosis in Patients with Pancreaticobiliary Duct Carcinoma Who Underwent Radical Surgical Resections
Clinical Significance of Para-Aortic Node Metastasis for Prognosis in Patients with Pancreaticobiliary Duct Carcinoma Who Underwent Radical Surgical Resections Open
Background: We investigated the significance of the para-aortic node (PALN) and other regional node metastases (RLN), reflecting malignant histological findings or poor patient prognosis, in patients with biliary duct cancers (BDC) and pan…
View article: 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters are associated with histological outcomes in superficial esophageal squamous cell carcinoma
18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters are associated with histological outcomes in superficial esophageal squamous cell carcinoma Open
Endoscopic submucosal dissection is a standard treatment for early esophageal squamous cell carcinoma. However, submucosal or lymphovascular invasion increases the risk of lymph node metastasis. Although 18F-fluorodeoxyglucose positron emi…
View article: Lifetime Follow-Up of a Patient with Metastatic Prostate Cancer Undergoing Multiple Surgical Resections: A Case Report
Lifetime Follow-Up of a Patient with Metastatic Prostate Cancer Undergoing Multiple Surgical Resections: A Case Report Open
BACKGROUND Prostate cancer (PC) often metastasizes after primary resection, and long-term survival following surgical removal of multiple pulmonary metastases is rare. We present a case of a surgeon who demonstrated long-term survival afte…
View article: Diagnosis and management of neonatal respiratory distress syndrome in Japan: A national survey
Diagnosis and management of neonatal respiratory distress syndrome in Japan: A national survey Open
In Japan, chest radiography and/or SMR are commonly used for the diagnosis of RDS and as the rationale for surfactant administration. Further studies from other countries are required to establish the ideal criteria for surfactant administ…
View article: Field Demonstration of Parallel Operation of Virtual Synchronous Controlled Grid-Forming Inverters and a Diesel Synchronous Generator in a Microgrid
Field Demonstration of Parallel Operation of Virtual Synchronous Controlled Grid-Forming Inverters and a Diesel Synchronous Generator in a Microgrid Open
With the growing shift toward renewable energy, attention focused on the disadvantages of current control inverter-based distributed generators, such as lack of grid-forming ability and inertia. To provide inertia support and grid-forming …
View article: Nationwide survey of late‐onset hemolysis in very low birthweight infants
Nationwide survey of late‐onset hemolysis in very low birthweight infants Open
Background In Japan, some cases of late‐onset acute hemolysis in very low birthweight (VLBW) infants have been reported. These cases had common features but the cause of hemolysis was unknown. The incidence and prognosis of this disease ar…
View article: Transient Analysis of Power System with All Inverter Power Sources
Transient Analysis of Power System with All Inverter Power Sources Open
In relatively small islands, diesel generators are the main power source, but in the near future, a large amount of renewable energy sources which are interconnected via inverter are expected to be introduced in terms of cost. The problem …
View article: Diaphragm ultrasound examination for congenital diaphragmatic eventration in two premature neonates
Diaphragm ultrasound examination for congenital diaphragmatic eventration in two premature neonates Open
Congenital diaphragmatic eventration (CDE) is always diagnosed by fluoroscopic examination. However, this technique is inappropriate for premature neonates because of risks of transport, hypothermia and ionising radiation. Herein, we descr…
View article: Unusual Course of Scimitar Syndrome Preceded by Lung Hypoplasia
Unusual Course of Scimitar Syndrome Preceded by Lung Hypoplasia Open
In patients with Scimitar syndrome, right pulmonary artery hypoplasia is considered to lead to right lung hypoplasia because of decrease in blood flow. However, there are no reports wherein the change was actually detected. Thus, the exact…
View article: Study on estimation of creep behaviour of concrete at early age considering temperature effect
Study on estimation of creep behaviour of concrete at early age considering temperature effect Open
Clarifying the creep behaviour of concrete at early age not only improves the accuracy of temperature stress analysis but also contributes to prediction accuracy and control measures in cracks caused by thermal stress. However, most past r…
View article: Resection of liposarcoma of the greater omentum: A case report and literature review
Resection of liposarcoma of the greater omentum: A case report and literature review Open
The diagnosis of liposarcoma with a lipomatous tumor is challenging, and resection should be considered for huge intra-abdominal lipomatous tumors.
View article: Pancreatic Duct-to-mucosa versus Invagination or Complete External Drainage Anastomosis in Case of Small Pancreatic Duct after Pancreaticoduodenectomy: Comparative Historical Review
Pancreatic Duct-to-mucosa versus Invagination or Complete External Drainage Anastomosis in Case of Small Pancreatic Duct after Pancreaticoduodenectomy: Comparative Historical Review Open
After pancreaticoduodenectomy (PD), pancreatic duct-to-mucosa anastomosis (PDM) has been usually applied which may prevent risk of pancreatic fistula (PF). In cases with a small pancreatic duct, however, PDM is difficult to complete. Proce…
View article: Relationship between serum ghrelin level and physiology in patients who underwent hepatectomy and pancreatectomy
Relationship between serum ghrelin level and physiology in patients who underwent hepatectomy and pancreatectomy Open
Aim: Ghrelin is a peptide that is secreted from the stomach and plays a role in appetite, weight gain, and skeletal muscle composition.\nIn the present clinical study, we examined the relationship between ghrelin level and physiology in pa…
View article: Influences of compounded human ghrelin for pancreatic fistula after distal pancreatectomy in a mouse model
Influences of compounded human ghrelin for pancreatic fistula after distal pancreatectomy in a mouse model Open
Ghrelin is a peptide that is secreted from the stomach and plays a role in appetite, weight gain, and skeletal muscle composition.\nCompounded human ghrelin (CHG) is a candidate drug to improve the nutritional status after pancreatic surge…
View article: Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer
Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer Open
The EGFR signal cascade regulates DPD expression via Sp1 in EGFR mutant cells. These results might be a step towards new therapies targeting Sp1 and DPD in NSCLC with different EGFR mutant status.
View article: Additional file 2: Table S1. of Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer
Additional file 2: Table S1. of Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer Open
Effects of 5-FU, gefitinib, and mithramycin A on cell proliferation in NSCLC cell lines. Cells were incubated with various concentrations of 5-FU for 72Â h, and cell viability was examined by WST-1 assay. The IC50 values of these drugs wer…
View article: Study on Resistant Properties for Cracking Caused by Shrinkage with Volume Change of Concrete Using High Volume Blast Furnace Slag Cement
Study on Resistant Properties for Cracking Caused by Shrinkage with Volume Change of Concrete Using High Volume Blast Furnace Slag Cement Open
In this study, using a new high volume blast furnace slag cement type C developed in order to improve the effect of inhibition of thermal crack in concrete and the resistance of thermal crack by means of expansion strain in early age obtai…
View article: Down-Regulation of Nogo-B Expression as a Newly Identified Feature of Intrahepatic Cholangiocarcinoma
Down-Regulation of Nogo-B Expression as a Newly Identified Feature of Intrahepatic Cholangiocarcinoma Open
Nogo-B, located in the endoplasmic reticulum, is an isoform belonging to the reticulon protein family, which is expressed specifically in cholangiocytes and non-parenchymal cells in the liver. Nogo-B expression is down-regulated with the p…
View article: Isolated Operation of Power System in Complex Housing Supplied by Battery Energy Storage System and Fuel Cells
Isolated Operation of Power System in Complex Housing Supplied by Battery Energy Storage System and Fuel Cells Open
Fuel cell as one of co-generation system and battery energy storage system can be used as power sources in an isolated power system in complex housing at blackout. This paper reports study results on this isolated power system. Simulation …
View article: Supplementary Material for: Prognostic Impact of the ABCC11/MRP8 Polymorphism in Adjuvant Oral Chemotherapy with S-1 for Non-Small Cell Lung Cancer
Supplementary Material for: Prognostic Impact of the ABCC11/MRP8 Polymorphism in Adjuvant Oral Chemotherapy with S-1 for Non-Small Cell Lung Cancer Open
Background: Postoperative 1-year administration of S-1, an oral derivative of 5-fluorouracil (5-FU), was shown to be feasible in lung cancer. The 5-year survival rates of postoperative patients treated with S-1 adjuvant chemotherapy and th…
View article: Synthesis and Characterization of a New Hydroquinone Derivative: Disodium <i>p</i>-Phenylene Diisostearyl Diphosphate
Synthesis and Characterization of a New Hydroquinone Derivative: Disodium <i>p</i>-Phenylene Diisostearyl Diphosphate Open
A novel amphiphilic hydroquinone derivative having a C18 alkyl chain phosphate attached to the hydroquinone (HQ) moiety was chemically synthesized. The thermal stability, distribution between organic and aqueous phases, and in vitro skin p…