Jun Kanazawa
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View article: Efficacy and safety of remimazolam for sedation during endoscopic procedures in Japanese: A prospective phase III clinical trial
Efficacy and safety of remimazolam for sedation during endoscopic procedures in Japanese: A prospective phase III clinical trial Open
Objectives Remimazolam is a general anesthetic with a short elimination half‐life and its pharmacokinetics are less affected by liver and kidney function. It may be useful for sedation during endoscopic procedures in patients. This single‐…
View article: P0681 Filgotinib for active Ulcerative Colitis in clinical practice - Effective treatment at week 8 is associated with higher clinical remission and persistence rates at Week 52 -
P0681 Filgotinib for active Ulcerative Colitis in clinical practice - Effective treatment at week 8 is associated with higher clinical remission and persistence rates at Week 52 - Open
Background There are few reports on therapeutic outcomes one year after starting filgotinib (FIL), a novel JAK inhibitor for ulcerative colitis (UC) in clinical practice. We studied the therapeutic outcomes and safety of FIL at 52 weeks af…
View article: Prognostic Factors for Patients with Small-Cell Lung Cancer Treated with Chemoimmunotherapy: A Retrospective Multicenter Study
Prognostic Factors for Patients with Small-Cell Lung Cancer Treated with Chemoimmunotherapy: A Retrospective Multicenter Study Open
Background: This study aimed to investigate prognostic factors for predicting the survival of patients with extensive-disease-stage small-cell lung cancer treated with chemoimmunotherapy. Methods: Patients were classified according to over…
View article: Effect of spray COAG mode on hemostasis in colorectal endoscopic submucosal dissection using inverse probability of treatment weight analysis
Effect of spray COAG mode on hemostasis in colorectal endoscopic submucosal dissection using inverse probability of treatment weight analysis Open
Objective Swift and forced COAG with an electrosurgical knife are commonly used for intraoperative hemostasis in colorectal endoscopic submucosal dissection (ESD). If bleeding cannot be stopped using an electrosurgical knife, cauterization…
View article: Implementation Rate of Bronchoscopy in Patients with Pulmonary Tuberculosis and the Incidence and Risk Factors of Concomitant Endobronchial Tuberculosis
Implementation Rate of Bronchoscopy in Patients with Pulmonary Tuberculosis and the Incidence and Risk Factors of Concomitant Endobronchial Tuberculosis Open
Background: Bronchoscopy is a mandatory tool used to diagnose endobronchial tuberculosis (EBTB); however, it is not routinely performed on all patients with pulmonary tuberculosis (PTB) because of the risk of exposure to airborne Mycobacte…
View article: The primary ciliary dyskinesia-related genetic risk score is associated with susceptibility to adult-onset asthma
The primary ciliary dyskinesia-related genetic risk score is associated with susceptibility to adult-onset asthma Open
Background Disturbance of mucociliary clearance is an important factor in the pathogenesis of asthma. We hypothesized that common variants in genes responsible for ciliary function may contribute to the development of asthma with certain p…
View article: Organizing Pneumonia in a Case of Cold Agglutinin Disease with Pulmonary Thrombosis
Organizing Pneumonia in a Case of Cold Agglutinin Disease with Pulmonary Thrombosis Open
Cold agglutinin disease is a subtype of autoimmune hemolytic anemia that occurs via the activation of specific anti-red blood cell antibodies (agglutinins) at low temperatures. Autoimmune hemolytic anemia has been reported to cause interst…
View article: Usefulness of malignant pleural effusion for early cytological diagnosis of mesothelioma <i>in situ</i>: A case report
Usefulness of malignant pleural effusion for early cytological diagnosis of mesothelioma <i>in situ</i>: A case report Open
Mesothelioma in situ (MIS) is defined as a preinvasive mesothelioma that forms a single layer of mild atypical mesothelial cells lining on the serosa surface of pleura. The atypical mesothelial cells present loss of BRCA-1 associated prote…
View article: Impact of sleep-related hypoventilation in patients with pleuroparenchymal fibroelastosis
Impact of sleep-related hypoventilation in patients with pleuroparenchymal fibroelastosis Open
Background Pleuroparenchymal fibroelastosis (PPFE) is a rare fibrosing lung disease with a predilection for the upper lobe and its progression causes hypoventilation, resulting in hypercapnia. Even though the association between sleep-rela…
View article: Common exacerbation-prone phenotypes across asthma and chronic obstructive pulmonary disease (COPD)
Common exacerbation-prone phenotypes across asthma and chronic obstructive pulmonary disease (COPD) Open
Background and objectives Chronic inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease (COPD), are complex syndromes with diverse clinical symptoms due to multiple pathophysiological conditions. In this …
View article: A Case of Pulmonary Metastasis of Breast Cancer 23 Years after Surgery Accompanied with Non-Tuberculous Mycobacterium Infection
A Case of Pulmonary Metastasis of Breast Cancer 23 Years after Surgery Accompanied with Non-Tuberculous Mycobacterium Infection Open
Recurrence of oestrogen receptor (ER)-positive breast cancer rarely occurs postoperatively after a long period. Breast cancer cells survive and settle in distant organs in a dormant state, a phenomenon known as “tumour dormancy.” Here, we …
View article: Treatment Outcomes of Endoscopic Hemostasis for Colonic Diverticular Bleeding
Treatment Outcomes of Endoscopic Hemostasis for Colonic Diverticular Bleeding Open
【目的】大腸憩室出血に対する内視鏡止血法の治療成績を明らかにする．
View article: ORMDL3/GSDMB genotype as a risk factor for early-onset adult asthma is linked to total serum IgE levels but not to allergic sensitization
ORMDL3/GSDMB genotype as a risk factor for early-onset adult asthma is linked to total serum IgE levels but not to allergic sensitization Open
ORMDL3/GSDMB is an important susceptibility gene for childhood-onset adult asthma in Japanese populations and this association is linked to elevated total serum IgE levels but not to allergic sensitization.
View article: P509 Long-term outcomes of adalimumab in patients with Crohn’s disease: Can a doubled dose of adalimumab improve outcomes?
P509 Long-term outcomes of adalimumab in patients with Crohn’s disease: Can a doubled dose of adalimumab improve outcomes? Open
In anti-TNF agent therapy for inflammatory bowel disease, one agent should be thoroughly used because of immunogenicity issues. We examined the long-term outcomes of treatment with adalimumab (ADA) and effect of a doubled dose of ADA on tr…