Jun Zhou
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View article: Optimizing Transmission FLASH Radiotherapy for Large-Field Post-Mastectomy Breast Treatment
Optimizing Transmission FLASH Radiotherapy for Large-Field Post-Mastectomy Breast Treatment Open
We investigated the effects of scanning speed, beam configuration, and dose-rate modeling on the FLASH effect in post-mastectomy proton transmission-beam (TB) planning and evaluated whether optimizing the spot-scanning path can enhance FLA…
View article: Gallbladder Mucinous Carcinoma in a Child with Metachromatic Leukodystrophy, Case Report and Literature Review
Gallbladder Mucinous Carcinoma in a Child with Metachromatic Leukodystrophy, Case Report and Literature Review Open
Background Metachromatic leukodystrophy (MLD) is an autosomal recessive genetic disorder caused by arylsulfatase A (ARSA) deficiency. Patients with MLD exhibit a high prevalence of gallbladder polyps and intestinal metaplasia. Although the…
View article: The Debate on RLVR Reasoning Capability Boundary: Shrinkage, Expansion, or Both? A Two-Stage Dynamic View
The Debate on RLVR Reasoning Capability Boundary: Shrinkage, Expansion, or Both? A Two-Stage Dynamic View Open
The ongoing debate on whether reinforcement learning with verifiable rewards (RLVR) expands or shrinks the reasoning capabilities of large language models (LLMs) remains unresolved. Some studies contend that RLVR mainly improves sampling e…
View article: AI-augmented prenatal care: a dual-modal fetal health assessment system integrating cardiotocography and uterine contraction synergy
AI-augmented prenatal care: a dual-modal fetal health assessment system integrating cardiotocography and uterine contraction synergy Open
Introduction Fetal heart monitoring (FHR) is a critical tool for assessing fetal health, but traditional methods rely on subjective physician interpretation, exhibiting significant variability that can lead to misdiagnosis and overtreatmen…
View article: SATE: Efficient knowledge distillation with implicit student-aware teacher ensembles
SATE: Efficient knowledge distillation with implicit student-aware teacher ensembles Open
View article: SSIT: A spatial–spectral interactive transformer for hyperspectral image denoising
SSIT: A spatial–spectral interactive transformer for hyperspectral image denoising Open
View article: A Model-Driven Multi-UAV Spectrum Map Fast Fusion Method for Strongly Correlated Data Environments
A Model-Driven Multi-UAV Spectrum Map Fast Fusion Method for Strongly Correlated Data Environments Open
Spectrum map fusion has emerged as an effective technique to enhance the accuracy of spectrum map construction. However, many existing fusion methods fail to address the strong correlation between spectrum data, resulting in sub-optimal pe…
View article: Clinical Outcomes of Anterior Asynclitism Deliveries in a District-Level Hospital: Insights for Primary Care Obstetrics
Clinical Outcomes of Anterior Asynclitism Deliveries in a District-Level Hospital: Insights for Primary Care Obstetrics Open
Background: Anterior asynclitism, a rare but high-risk obstetric dystocia, disrupts normal fetal descent and is associated with increased maternal and neonatal complications. Despite its clinical significance, early diagnosis remains chall…
View article: GRACE/GFO and Swarm Observation Analysis of the 2023–2024 Extreme Drought in the Amazon River Basin
GRACE/GFO and Swarm Observation Analysis of the 2023–2024 Extreme Drought in the Amazon River Basin Open
The Amazon River Basin (ARB) experienced an extreme drought from summer 2023 to spring 2024, driven by complex interactions among multiple climatic and environmental factors. A detailed investigation into this drought is crucial in underst…
View article: Unified Medical Image Segmentation with State Space Modeling Snake
Unified Medical Image Segmentation with State Space Modeling Snake Open
Unified Medical Image Segmentation (UMIS) is critical for comprehensive anatomical assessment but faces challenges due to multi-scale structural heterogeneity. Conventional pixel-based approaches, lacking object-level anatomical insight an…
View article: Lymphangiomatosis with pulmonary, mediastinal, and spinal involvement in a pediatric patient: a case report
Lymphangiomatosis with pulmonary, mediastinal, and spinal involvement in a pediatric patient: a case report Open
Background Lymphangiomatosis is a rare disorder characterized by abnormal proliferation and dilation of lymphatic vessels, resulting in non-specific clinical manifestations. This report describes the case of an 8-year-old male patient with…
View article: A novel L1C.5 RFLP-1-4-4 recombinant porcine reproductive and respiratory syndrome virus between wild-type virus and a modified-live virus vaccine is highly pathogenic to piglets
A novel L1C.5 RFLP-1-4-4 recombinant porcine reproductive and respiratory syndrome virus between wild-type virus and a modified-live virus vaccine is highly pathogenic to piglets Open
Porcine reproductive and respiratory syndrome (PRRS) is a severe viral disease in pigs caused by porcine reproductive and respiratory syndrome virus (PRRSV). It poses a severe threat to the global swine breeding industry. Recently, the eme…
View article: Comparison of proton and photon therapy in stereotactic arrhythmia radioablation for ventricular tachycardia
Comparison of proton and photon therapy in stereotactic arrhythmia radioablation for ventricular tachycardia Open
Proton therapy for STAR demonstrated significant potential for OARs sparing compared to photon therapy for VT, while maintaining equivalent target coverage. These findings highlight the potential of proton therapy to improve outcomes for V…
View article: Integration of Innovative Materials and Biotechnology in Joint Repair and Regeneration
Integration of Innovative Materials and Biotechnology in Joint Repair and Regeneration Open
Musculoskeletal disorders, particularly osteoarthritis (OA), rheumatoid arthritis (RA), and post-traumatic osteoarthritis, are on the rise due to aging populations and increasing rates of obesity. The advent of regenerative medicine, parti…
View article: Enhancing LLM Tool Use with High-quality Instruction Data from Knowledge Graph
Enhancing LLM Tool Use with High-quality Instruction Data from Knowledge Graph Open
Teaching large language models (LLMs) to use tools is crucial for improving their problem-solving abilities and expanding their applications. However, effectively using tools is challenging because it requires a deep understanding of tool …
View article: Beyond energy metabolism: ketogenic diet and β-hydroxybutyrate protect against intestinal ischemia-reperfusion injury through anti-inflammatory and barrier-preserving effects
Beyond energy metabolism: ketogenic diet and β-hydroxybutyrate protect against intestinal ischemia-reperfusion injury through anti-inflammatory and barrier-preserving effects Open
Intestinal ischemia-reperfusion injury (IRI) is a significant clinical challenge with limited effective treatments. This study investigated the protective effects of ketogenic diet (KD) and β-hydroxybutyrate (BHB) against intestinal IRI us…
View article: Marginal land identification and grain production capacity prediction of the coverage area of western route of China’s South-to-North Water Diversion Project
Marginal land identification and grain production capacity prediction of the coverage area of western route of China’s South-to-North Water Diversion Project Open
The western route of the South-to-North Water Diversion Project (SNWDP) provides opportunities to improve agricultural production by altering regional water availability. This study identifies and evaluates marginal land—defined as undevel…
View article: Single-wavelength near-infrared imaging and machine learning for detecting Queensland fruit fly damage in cherries
Single-wavelength near-infrared imaging and machine learning for detecting Queensland fruit fly damage in cherries Open
View article: Construction of a novel disulfidptosis-associated lncRNAs signature for risk features and immunotherapy in breast cancer
Construction of a novel disulfidptosis-associated lncRNAs signature for risk features and immunotherapy in breast cancer Open
A novel prognostic model and classification for BRCA was established, which can provide robust scientific support for tailoring personalized treatment strategies for immune therapy.
View article: Identification of Key Genes Controlling Flavor Changes During Jujube Fruit Development by Integrating Transcriptome and Metabolome Analysis
Identification of Key Genes Controlling Flavor Changes During Jujube Fruit Development by Integrating Transcriptome and Metabolome Analysis Open
To elucidate the molecular mechanisms that underlie jujube (Ziziphus jujuba) flavor synthesis, we integrated transcriptomic and metabolomic analyses on the ‘Lingwuchangzao’ cultivar across seven developmental stages. Our multi-omics approa…
View article: Hydronephrosis-Associated Renal Fibrosis: Clinical Validation of Spp1 as a Biomarker and Therapeutic Target
Hydronephrosis-Associated Renal Fibrosis: Clinical Validation of Spp1 as a Biomarker and Therapeutic Target Open
Background: Renal fibrosis is a key driver of chronic kidney disease, often leading to end-stage renal disease (ESRD). Secreted phosphoprotein 1 (Spp1) is implicated in fibrotic processes, but its specific role in renal fibrosis, particula…
View article: SAM-R1: Leveraging SAM for Reward Feedback in Multimodal Segmentation via Reinforcement Learning
SAM-R1: Leveraging SAM for Reward Feedback in Multimodal Segmentation via Reinforcement Learning Open
Leveraging multimodal large models for image segmentation has become a prominent research direction. However, existing approaches typically rely heavily on manually annotated datasets that include explicit reasoning processes, which are co…
View article: Cross-source transformer-based neighborhood contrastive learning for joint classification of hyperspectral and LiDAR Data
Cross-source transformer-based neighborhood contrastive learning for joint classification of hyperspectral and LiDAR Data Open
View article: Model-free methodology for thin film thickness analysis by spectroscopic reflectometry
Model-free methodology for thin film thickness analysis by spectroscopic reflectometry Open
View article: Hierarchical Context Learning of object components for unsupervised semantic segmentation
Hierarchical Context Learning of object components for unsupervised semantic segmentation Open
View article: HSLiNets: Evaluating Band Ordering Strategies in Hyperspectral and LiDAR Fusion
HSLiNets: Evaluating Band Ordering Strategies in Hyperspectral and LiDAR Fusion Open
The integration of hyperspectral imaging (HSI) and Light Detection and Ranging (LiDAR) data provides complementary spectral and spatial information for remote sensing applications. While previous studies have explored the role of band sele…
View article: TraNCE: Transformative Non-linear Concept Explainer for CNNs
TraNCE: Transformative Non-linear Concept Explainer for CNNs Open
Convolutional neural networks (CNNs) have succeeded remarkably in various computer vision tasks. However, they are not intrinsically explainable. While the feature-level understanding of CNNs reveals where the models looked, concept-based …
View article: Lymphangiomatosis with pulmonary, mediastinal, and spinal Involvement in a pediatric patient: a case report
Lymphangiomatosis with pulmonary, mediastinal, and spinal Involvement in a pediatric patient: a case report Open
Background Lymphangiomatosis is a rare disorder characterized by abnormal proliferation and dilation of lymphatic vessels, resulting in non-specific clinical manifestations. This report describes the case of an 8-year-old male patient with…
View article: PD-1 antibody camrelizumab plus apatinib and SOX as first-line treatment in patients with AFP-producing gastric or gastro-esophageal junction adenocarcinoma (CAP 06): a multi-center, single-arm, phase 2 trial
PD-1 antibody camrelizumab plus apatinib and SOX as first-line treatment in patients with AFP-producing gastric or gastro-esophageal junction adenocarcinoma (CAP 06): a multi-center, single-arm, phase 2 trial Open
Alpha-fetoprotein-producing gastric or gastro-esophageal junction (AFP-G/GEJ) cancer, a rare gastric cancer subtype, exhibits increased angiogenesis and more immunosuppression than non-AFP-G/GEJ cancer. The potential benefits of anti-angio…
View article: 51P A preliminary study on the application of a strong combination induction of immune checkpoint inhibitors with targeted therapy and chemotherapy in head and neck tumors
51P A preliminary study on the application of a strong combination induction of immune checkpoint inhibitors with targeted therapy and chemotherapy in head and neck tumors Open