Junfei Zhou
YOU?
Author Swipe
View article: Highly oxygenated dihydrostilbenoids and flavones from the aerial part of Glycyrrhiza uralensis and their antimicrobial activities
Highly oxygenated dihydrostilbenoids and flavones from the aerial part of Glycyrrhiza uralensis and their antimicrobial activities Open
Background Multidrug-resistant bacteria (MDRB) represent a significant global challenge due to their high mortality rates, substantial economic burden, and rapid spread. Traditional triple or quadruple therapies have demonstrated limited e…
View article: Chemical constituents of the aerial parts of <i>Mitracarpus hirtus</i> (L.) DC (Rubiaceae)
Chemical constituents of the aerial parts of <i>Mitracarpus hirtus</i> (L.) DC (Rubiaceae) Open
A phytochemical investigation of the aerial parts of Mitracarpus hirtus afforded thirteen compounds, including a new naphthoquinone di-glycoside (1), three isopentenyl isoflavones (2−4), four flavonoids (5−8), three iridoid glycosides (9 −…
View article: Polyoxygenated (9β-H)-Pimarane Derivatives from Leaves of Icacina oliviformis and Their Anti-tumor Activities
Polyoxygenated (9β-H)-Pimarane Derivatives from Leaves of Icacina oliviformis and Their Anti-tumor Activities Open
Thirteen novel polyoxygenated (9β-H)-pimarane derivatives, icacinolides A–G (1–7), oliviformislactones C–H (8–13), and two known analogs (14 and 15), were isolated from the leaves of Icacina oliviformis. Their structures were constructed b…
View article: CCDC 2211348: Experimental Crystal Structure Determination
CCDC 2211348: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2211338: Experimental Crystal Structure Determination
CCDC 2211338: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2221272: Experimental Crystal Structure Determination
CCDC 2221272: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2211336: Experimental Crystal Structure Determination
CCDC 2211336: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2194257: Experimental Crystal Structure Determination
CCDC 2194257: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2194256: Experimental Crystal Structure Determination
CCDC 2194256: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Oxalactam A, a Novel Macrolactam with Potent Anti-Rhizoctonia solani Activity from the Endophytic Fungus Penicillium oxalicum
Oxalactam A, a Novel Macrolactam with Potent Anti-Rhizoctonia solani Activity from the Endophytic Fungus Penicillium oxalicum Open
A novel macrolactam named oxalactam A (1), three known dipeptides (2–4) as well as other known alkaloids (5–7) were obtained from the endophytic fungus Penicillium oxalicum, which was derived from the tuber of Icacina trichantha (Icacinace…
Efficacy and Safety of Remimazolam Besylate Combined with Alfentanil in Painless Gastroscopy: A Randomized, Single‐Blind, Parallel Controlled Study Open
Background . The efficacy and adverse reactions of remimazolam besylate (RB) in combination with alfentanil in patients with painless gastroscopy remain unclear. Objective . The aim of the study is to observe the efficacy and adverse react…
Supplementary Material for: Extracorporeal Carbon Dioxide Removal in Patients with Acute Respiratory Distress Syndrome or Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis Open
Background: Extracorporeal carbon dioxide removal (ECCO2R) was used to prevent invasive mechanical ventilation and associated mechanical damage in patients with acute respiratory distress syndrome (ARDS). Objectives: This study aimed to in…
Comparison of the Jcerity Endoscoper Airway with the LMA Supreme for Airway Management in Patients Undergoing Cerebral Aneurysm Embolization Open
Background Interventional embolization of cerebral aneurysms often requires anticoagulation and antiplatelet therapy during perioperative period. A new type of laryngeal mask airway (Jcerity Endoscoper Airway)with a unique design may cause…
Tumor necrosis factor α inhibition overcomes immunosuppressive M2b macrophage-induced bevacizumab resistance in triple-negative breast cancer Open
Bevacizumab in neoadjuvant therapy provides a new hope of improved survival for patients with triple-negative breast cancer (TNBC) by targeting vascular endothelial growth factor in combination with chemotherapy, but curative effect is lim…
Protein Tyrosine Phosphatase 1B Inhibitory Iridoids from <i>Psydrax subcordata</i> Open
Phytochemical investigation of the leaves and bark of Psydrax subcordata has led to the isolation of six new iridoids, subcordatanols I-V (1-4 and 6) and 1-O-methylcrescentin I (5), along with two known analogues (7 and 8). Among them, sub…
Recombinant expressing angiopep-2 fused anti-VEGF single chain Fab (scFab) could cross blood–brain barrier and target glioma Open
In 2009, the FDA approved bevacizumab for the treatment of adult patients diagnosed with recurrent glioblastoma. However, the poor permeability of the macromolecules across the blood–brain barrier, determined by multifactorial anatomical a…
The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction Open
The propofol can impair memory and learning of rats and induce cognition dysfunction through the interplay of NMDA receptor and BDNF-TrkB-CREB signaling pathway.
Acetylcholinesterase Inhibitory Alkaloids from the Whole Plants of <i>Zephyranthes carinata</i> Open
Eleven new alkaloids (1-11), classified as the 12-acetylplicamine (1), N-deformyl-seco-plicamine (2), plicamine (3-6), 4a-epi-plicamine (7), seco-plicamine (8), and lycorine (9-11) framework types, along with 15 known alkaloids (12-26) wer…
CCDC 1542685: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
Triterpenoid Glycosides from the Leaves of <i>Lyonia ovalifolia</i> var. <i>hebecarpa</i> and Their Antitumor Activities Open
a 黑龙江中医药大学药学院 哈尔滨 150040) ( b 华中科技大学同济医学院药学院 武汉 430030) ( c 佳木斯大学药学院 佳木斯 1504007) 摘要 利用柱层析和高效液相色谱等分离技术从毛果南烛 Lyonia ovalifolia var.hebecarpa 的叶中分离得到了 3 个三萜 皂苷类化合物, 借助 HRESIMS 和 NMR 等波谱手段以及化学方法鉴定其结构分别 3β-O-ɑ-L-阿拉伯吡喃糖氧基-齐墩 果-12-烯-23,25-二醇(1)、…
CCDC 1542687: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
Galanthamine, Plicamine, and Secoplicamine Alkaloids from <i>Zephyranthes candida</i> and Their Anti-acetylcholinesterase and Anti-inflammatory Activities Open
Sixteen new alkaloids belonging to the galanthamine (1-6), plicamine (7-14), and secoplicamine (15 and 16) classes, together with eight known analogues (17-24), were isolated from Zephyranthes candida. The structures of 1-16 were determine…
Molecular docking and 3D-QSAR studies on the glucocorticoid receptor antagonistic activity of hydroxylated polychlorinated biphenyls Open
The glucocorticoid receptor (GR) antagonistic activities of hydroxylated polychlorinated biphenyls (HO-PCBs) were recently characterised. To further explore the interactions between HO-PCBs and the GR, and to elucidate structural character…
CCDC 1415215: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
CCDC 1048150: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …