Junfeng Zhang
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View article: Efficacy and safety of combined lumbar plexus and quadratus lumborum block via Shamrock approach at L3 in total hip arthroplasty: a prospective randomized controlled trial
Efficacy and safety of combined lumbar plexus and quadratus lumborum block via Shamrock approach at L3 in total hip arthroplasty: a prospective randomized controlled trial Open
gov PRS: Record Summary NCT04266236.
View article: Commentary: Transcription factor MEF2D regulates aberrant expression of ACSL3 and enhances sorafenib resistance by inhibiting ferroptosis in HCC
Commentary: Transcription factor MEF2D regulates aberrant expression of ACSL3 and enhances sorafenib resistance by inhibiting ferroptosis in HCC Open
View article: Oral Treatment with the Vimentin-Targeting Compound ALD-R491 Mitigates Hyperinflammation, Multi-Organ Injury, and Mortality in CLP-Induced Septic Mice
Oral Treatment with the Vimentin-Targeting Compound ALD-R491 Mitigates Hyperinflammation, Multi-Organ Injury, and Mortality in CLP-Induced Septic Mice Open
Sepsis is a life-threatening condition driven by a dysregulated host response to infection, with high mortality and few treatment options. Decades of failed drug development underscore the urgent need for therapies with novel mechanisms of…
View article: Cardiac electrophysiological responses to traffic pollution in adults with or without chronic cardiopulmonary diseases
Cardiac electrophysiological responses to traffic pollution in adults with or without chronic cardiopulmonary diseases Open
Although between-group comparisons were not statistically significant, COPD patients showed numerically larger electrophysiological changes and reductions in NO2-cLA levels following short-term exposure to traffic pollution. Use…
View article: Correlations between human alveolar macrophage particulate matter load, air pollution particulate matter levels, and systemic inflammation markers in Mexico City
Correlations between human alveolar macrophage particulate matter load, air pollution particulate matter levels, and systemic inflammation markers in Mexico City Open
This study explores potential associations among ambient particulate matter (PM) exposure, PM load in alveolar macrophage (AM), and biomarkers collected from 53 healthy, adult, nonsmoking residents of the Iztapalapa and Iztacalco municipal…
View article: Correction: Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis
Correction: Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis Open
View article: Nitrated Fatty Acids and Susceptibility of COPD to Air Pollution: Evidence from a Randomized Crossover Study
Nitrated Fatty Acids and Susceptibility of COPD to Air Pollution: Evidence from a Randomized Crossover Study Open
Previous studies documented increased nitrative stress and susceptibility to air pollution among individuals with chronic inflammatory conditions. This study examines the role of anti-inflammatory and cardioprotective nitrated fatty acids …
View article: Correction: The effect of resveratrol, curcumin and quercetin combination on immuno-suppression of tumor microenvironment for breast tumor-bearing mice
Correction: The effect of resveratrol, curcumin and quercetin combination on immuno-suppression of tumor microenvironment for breast tumor-bearing mice Open
View article: <scp>ALX</scp> / <scp>FPR2</scp> Contributes to Serum Amyloid A‐Induced Lung Neutrophil Recruitment Following Acute Ozone Exposure
<span>ALX</span> / <span>FPR2</span> Contributes to Serum Amyloid A‐Induced Lung Neutrophil Recruitment Following Acute Ozone Exposure Open
Ozone (O 3 ) is a toxic air pollutant that causes pulmonary inflammation, neutrophil recruitment, and lung injury. Part of the inflammatory response to O 3 includes altered expression of formyl peptide receptor 2 (ALX/FPR2), a G protein‐co…
View article: Standardization of case definition and development of early-warning model for acute respiratory infection syndromes based on Yinzhou Regional Health Information Platform
Standardization of case definition and development of early-warning model for acute respiratory infection syndromes based on Yinzhou Regional Health Information Platform Open
Background Acute respiratory infection syndromes (ARIs) pose major public health challenges due to their high infectivity, rapid transmission, and the lack of standardized definitions balancing sensitivity and specificity in current survei…
View article: Combined Effect of HF‐rTMS and Whole‐Body Vibration Exercise on Cognitive Efficiency in Esports Players With or Without Sedentary Behaviors: A Randomized Controlled Trial
Combined Effect of HF‐rTMS and Whole‐Body Vibration Exercise on Cognitive Efficiency in Esports Players With or Without Sedentary Behaviors: A Randomized Controlled Trial Open
Background The present study investigated the effects of high‐frequency repetitive transcranial magnetic stimulation (HF‐rTMS), whole‐body vibration training (WBVT), and a combination of HF‐rTMS and WBVT interventions on cognitive performa…
View article: Quality and influencing factors of hospice care outcomes in patients with advanced cancer: a cross-sectional study based on symptom management theory
Quality and influencing factors of hospice care outcomes in patients with advanced cancer: a cross-sectional study based on symptom management theory Open
Background Although the research and development of new drugs and the improvement of medical technology have made some progress in cancer treatment, the quality of life of cancer patients is still low, and the development of hospice care i…
View article: HSA Adductomics in the Shanghai Women’s Health Study Links Lung Cancer in Never-Smokers with Air Pollution, Redox Biology, and One-Carbon Metabolism
HSA Adductomics in the Shanghai Women’s Health Study Links Lung Cancer in Never-Smokers with Air Pollution, Redox Biology, and One-Carbon Metabolism Open
Nearly one fourth of lung cancers occur among never-smokers and are predominately lung adenocarcinomas (LUADs) that are distinct from smoking-related cancers. Causal links between LUADs in never-smokers have been attributed to reactive oxy…
View article: Children’s Lung Function Was Lower in 2017–2018 than in 1995–1996: The Roles of Air Quality Change and Individual-Level Risk Factors
Children’s Lung Function Was Lower in 2017–2018 than in 1995–1996: The Roles of Air Quality Change and Individual-Level Risk Factors Open
Air quality has improved while the lifestyle of children has changed substantially over the past 2 decades in four Chinese cities. It is unknown how these changes affected the lung function of children. We analyzed data collected in 1995-1…
View article: LncRNA LINC01128 promotes prostate cancer cell proliferation, metastasis, and epithelial-mesenchymal transition by modulating miR-27b-3p
LncRNA LINC01128 promotes prostate cancer cell proliferation, metastasis, and epithelial-mesenchymal transition by modulating miR-27b-3p Open
View article: Atractylenolide I prevents acute liver failure in mouse by regulating M1 macrophage polarization
Atractylenolide I prevents acute liver failure in mouse by regulating M1 macrophage polarization Open
Acute liver failure (ALF) is a life-threatening clinical syndrome with a substantial risk of mortality. A murine model of lipopolysaccharide (LPS)- and D-galactosamine (D-GalN)-induced ALF is widely used to investigate the underlying mecha…
View article: P-1398. Implementation of a Doxycycline for Post-Exposure Prophylaxis Protocol at a Large Academic HIV Clinic
P-1398. Implementation of a Doxycycline for Post-Exposure Prophylaxis Protocol at a Large Academic HIV Clinic Open
Background The use of doxycycline post-exposure prophylaxis (DoxyPEP) lowers the incidence of gonorrhea, chlamydia, and syphilis in men who have sex with men and transgender women living with HIV or taking pre-exposure prophylaxis (PrEP) f…
View article: P-1646. Assessing Antibiotic Adverse Drug Events from Walk-In Clinics at an Academic Healthcare System
P-1646. Assessing Antibiotic Adverse Drug Events from Walk-In Clinics at an Academic Healthcare System Open
Background Outpatient antibiotic adverse drug event (ADE) rates are largely unknown. This project aimed to evaluate methods for collecting data on antibiotic ADEs and report antibiotic ADE data from 8 walk-in clinics (WICs) at Vanderbilt U…
View article: Gestational exposure to PM2.5, NO2, and sex steroid hormones: Identifying critical windows of exposure in the Rochester UPSIDE Cohort
Gestational exposure to PM2.5, NO2, and sex steroid hormones: Identifying critical windows of exposure in the Rochester UPSIDE Cohort Open
Background: Sex steroid hormones are critical for maintaining pregnancy and optimal fetal development. Air pollutants are potential endocrine disruptors that may disturb sex steroidogenesis during pregnancy, potentially leading to adverse …
View article: Associations between cardiovascular-kidney-metabolic syndrome and disability in activities of daily living: a nationwide longitudinal study among the middle-aged and older adults in China
Associations between cardiovascular-kidney-metabolic syndrome and disability in activities of daily living: a nationwide longitudinal study among the middle-aged and older adults in China Open
Background Activities in daily living (ADLs) disability triggered by aging population and chronic diseases in the middle-aged and older adults has become a major public health challenge. Cardiovascular-kidney-metabolic (CKM) syndrome, as a…
View article: Parameter Sensitivity Analysis of a Multiphysics Coupling Model for Performance Enhancement of Pemec
Parameter Sensitivity Analysis of a Multiphysics Coupling Model for Performance Enhancement of Pemec Open
View article: complete original data in three experiments for global (meta-)memory
complete original data in three experiments for global (meta-)memory Open
complete original data in three behavioral experiments for global (meta-)memory superiority effect of induced insight
View article: Melatonin supplementation and oxidative DNA damage repair capacity among night shift workers: a randomised placebo-controlled trial
Melatonin supplementation and oxidative DNA damage repair capacity among night shift workers: a randomised placebo-controlled trial Open
Objectives A decreased ability to repair oxidative DNA damage, due to melatonin suppression, is a compelling mechanism by which night shift workers are at an increased risk of cancer. We sought to determine if melatonin supplementation wou…
View article: Clean Process for Preparing High-Purity Mn₂O₃ Via Sulfite Precipitation and Application in Lithium Manganate
Clean Process for Preparing High-Purity Mn₂O₃ Via Sulfite Precipitation and Application in Lithium Manganate Open
View article: Benzo[<i>a</i>]pyrene and phenanthrene hemoglobin adducts as biomarkers of longer-term air pollution exposure
Benzo[<i>a</i>]pyrene and phenanthrene hemoglobin adducts as biomarkers of longer-term air pollution exposure Open
PAH-hemoglobin adduct levels were associated with cumulative PM 2.5 exposure over the lifespan of red blood cells, demonstrating their utility as biomarkers for longer-term exposure.
View article: Sappanone A Ameliorates Concanavalin A-induced Immune-Mediated Liver Injury by Regulating M1 Macrophage Polarization
Sappanone A Ameliorates Concanavalin A-induced Immune-Mediated Liver Injury by Regulating M1 Macrophage Polarization Open
View article: Study on the anti-colon cancer effect of Renshen Yangrong decoction based on network pharmacology, molecular docking, and in vivo and in vitro experiments
Study on the anti-colon cancer effect of Renshen Yangrong decoction based on network pharmacology, molecular docking, and in vivo and in vitro experiments Open
View article: Reduction in polycyclic aromatic hydrocarbon exposure in Beijing following China’s clean air actions
Reduction in polycyclic aromatic hydrocarbon exposure in Beijing following China’s clean air actions Open
Exposure to polycyclic aromatic hydrocarbons (PAHs) in the Chinese population was among the highest globally and associated with various adverse effects. This study examines the impact of China's two-phase clean air initiatives, namely the…
View article: Modeling the Effects of Policies that Restrict Tobacco Retail Outlets on Prenatal Smoke Exposure and Perinatal Health Care Utilization
Modeling the Effects of Policies that Restrict Tobacco Retail Outlets on Prenatal Smoke Exposure and Perinatal Health Care Utilization Open
Tobacco retail outlet (TRO) density has been associated with increased cotinine levels in pregnant persons and their children. As such, the higher densities of TROs may represent higher levels of active smoking during pregnancy. The purpos…
View article: Association of Preconception Air Pollution Exposure with Growth Trajectory in Children
Association of Preconception Air Pollution Exposure with Growth Trajectory in Children Open