Jungmoo Huh
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View article: Naturally Occurring PCSK9 Inhibitors: An Updated Review
Naturally Occurring PCSK9 Inhibitors: An Updated Review Open
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key modulator of low-density lipoprotein cholesterol (LDL-C) levels and emerged as an attractive therapeutic target for the treatment of hypercholesterolemia and cardiovascular dis…
View article: Gaylussacin, a stilbene glycoside, inhibits chronic obstructive pulmonary disease in mice
Gaylussacin, a stilbene glycoside, inhibits chronic obstructive pulmonary disease in mice Open
View article: The Phytochemistry and Pharmacology of Onocleaceae Plants: Pentarhizidium orientale, Pentarhizidium intermedium, and Matteuccia struthiopteris—A Review
The Phytochemistry and Pharmacology of Onocleaceae Plants: Pentarhizidium orientale, Pentarhizidium intermedium, and Matteuccia struthiopteris—A Review Open
The Onocleaceae family, a small group within the Pteridophytes, comprises four genera, but has been phytochemically studied mainly for Pentarhizidium orientale, Pentarhizidium intermedium, and Matteuccia struthiopteris. To date, a total of…
View article: Alkaloids and Coumarins with Adiponectin-Secretion-Promoting Activities from the Leaves of <i>Orixa japonica</i>
Alkaloids and Coumarins with Adiponectin-Secretion-Promoting Activities from the Leaves of <i>Orixa japonica</i> Open
Fractionation of a methanol extract of Orixa japonica leaves led to the identification of five new quinoline alkaloids (1, 2, 4, 8, and 9), three new coumarins (15, 17, and 19)…
View article: Utility of fatty acid profile and in vitro immune cell activation for chemical and biological standardization of Arthrospira/Limnospira
Utility of fatty acid profile and in vitro immune cell activation for chemical and biological standardization of Arthrospira/Limnospira Open
View article: Complete plastid and 45S rDNA sequences allow authentication of Liriope platyphylla and Ophiopogon japonicus
Complete plastid and 45S rDNA sequences allow authentication of Liriope platyphylla and Ophiopogon japonicus Open
Liriope platyphylla F.T. Wang & Tang and Ophiopogon japonicus (Thunb.) Ker Gawl are morphologically similar perennial herbaceous plants belonging to the Asparagaceae family used as evergreen ornamental plants as well as for medicinal purpo…
View article: Acylated saponins and flavonoid glycosides from the fruits of Stewartia koreana
Acylated saponins and flavonoid glycosides from the fruits of Stewartia koreana Open
View article: Potential of N-trans feruloyl tyramine from Lycium barbarum fruit extract on neurogenesis and neurotrophins; targeting TrkA/ERK/CREB signaling pathway
Potential of N-trans feruloyl tyramine from Lycium barbarum fruit extract on neurogenesis and neurotrophins; targeting TrkA/ERK/CREB signaling pathway Open
View article: Chemical Constituents with Inhibitory Activities on Proprotein Convertase Subtilisin/kexin Type 9 Expression from the Aerial Parts of Penthorum chinense
Chemical Constituents with Inhibitory Activities on Proprotein Convertase Subtilisin/kexin Type 9 Expression from the Aerial Parts of Penthorum chinense Open
Background: Penthorum chinense has been used in East Asia for the treatment of cholecystitis, infectious hepatitis, and jaundice. So far there is no report regarding proprotein convertase subtilisin/kexin type 9 inhibitory constituents fro…
View article: Combined MS/MS-NMR Annotation Guided Discovery of Iris lactea var. chinensis Seed as a Source of Viral Neuraminidase Inhibitory Polyphenols
Combined MS/MS-NMR Annotation Guided Discovery of Iris lactea var. chinensis Seed as a Source of Viral Neuraminidase Inhibitory Polyphenols Open
In this study, the chemical diversity of polyphenols in Iris lactea var. chinensis seeds was identified by combined MS/MS-NMR analysis. Based on the annotated chemical profile, the isolation of stilbene oligomers was conducted, and consequ…
View article: Standardized Extract of Atractylodis Rhizoma Alba and Fructus Schisandrae Ameliorates Coughing and Increases Expectoration of Phlegm
Standardized Extract of Atractylodis Rhizoma Alba and Fructus Schisandrae Ameliorates Coughing and Increases Expectoration of Phlegm Open
Cough and phlegm frequently occur in respiratory diseases like upper respiratory tract infections, acute bronchitis, and chronic obstructive pulmonary diseases. To relieve these symptoms and diseases, various ingredients are being used des…
View article: Comprehensive Characterization of Lignans from Forsythia viridissima by UHPLC-ESI-QTOF-MS, and Their NO Inhibitory Effects on RAW 264.7 Cells
Comprehensive Characterization of Lignans from Forsythia viridissima by UHPLC-ESI-QTOF-MS, and Their NO Inhibitory Effects on RAW 264.7 Cells Open
Lignans are known to be an important class of phenylpropanoid secondary metabolites. In the course of our studies on the chemodiversity of lignans, the necessity arose to develop a method for the fast detection and identification of bioact…
View article: Natalenamides A–C, Cyclic Tripeptides from the Termite-Associated Actinomadura sp. RB99
Natalenamides A–C, Cyclic Tripeptides from the Termite-Associated Actinomadura sp. RB99 Open
In recent years, investigations into the biochemistry of insect-associated bacteria have increased. When combined with analytical dereplication processes, these studies provide a powerful strategy to identify structurally and/or biological…
View article: <i>C</i>-Methylated Flavonoid Glycosides from <i>Pentarhizidium orientale</i> Rhizomes and Their Inhibitory Effects on the H1N1 Influenza Virus
<i>C</i>-Methylated Flavonoid Glycosides from <i>Pentarhizidium orientale</i> Rhizomes and Their Inhibitory Effects on the H1N1 Influenza Virus Open
Thirteen C-methylated flavonoid glycosides (1-13), along with 15 previously known flavonoids (14-28), were isolated from rhizomes of Pentarhizidium orientale. Among these compounds, matteuorienates D-K (1-8) were obtained as analogues of m…