Explanipedia

A H2-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration Open

Cin Kong, Chao Si, Haofeng Liu, Yawen Wang, J.W. Qiao , et al. · 2025

The repair of infected bone defects (IBDs) presents a significant clinical challenge due to recurrent infections and inflammation. Characterized by reactive oxygen species (ROS) bursts and mitochondrial dysfunction, IBDs generates to a vic…

A rapid and automated primary screening platform for breast cancer percutaneous biopsies Open

Jiawei Gao, Feiran Zhang, Mengxin Li, Junhu Zhang, Song Dong , et al. · 2025

In clinical practice, needle biopsy has emerged as a powerful tool in diagnosing numerous suspicious breast masses detected through medical imaging. However, a notable proportion of needle biopsies are negative and the disrupted tissue arc…

Hydrogel system with growth cone-targeted hydroxyapatite nanorods: Regulating calcium signals for peripheral nerve injury repair Open

Zhenghang Li, Xiaoduo Tang, Haitao Yang, Laijin Lu, Junhu Zhang , et al. · 2025

Calcium (Ca²⁺) regulation assumes a critical role in the repair course of peripheral nerve injury (PNI). However, effective calcium sources capable of providing sustained Ca²⁺ signals to promote growth cone extension remain limited. Herein…

Effect of Defects on Piezoelectric Properties of Sm-Doped K0.47Na0.53NbO3 Ceramics Open

P.B. Wu, Dandan Wang, Fengzi Zhou, Yongpeng Ren, Junhu Zhang , et al. · 2025

Rare earth element (Sm)-doped potassium sodium niobate (KNN)-based ceramics are fabricated using spark plasma sintering method and their properties are investigated. The results show that all the samples crystallize in a typical perovskite…

Advances in Microfluidic Single-Cell RNA Sequencing and Spatial Transcriptomics Open

Yueqiu Sun, Nianzuo Yu, Junhu Zhang, Yang Bai · 2025

The development of micro- and nano-fabrication technologies has greatly advanced single-cell and spatial omics technologies. With the advantages of integration and compartmentalization, microfluidic chips are capable of generating high-thr…

VEGF-A Remissions Brown Adipocyte Function Following Combined Exposure to Bisphenol A and a High-Fat Diet Open

Huihong Zhang, Qingqing Feng, Xiaoli Wu, Ruiting Wang, Qi Chang , et al. · 2025

Obesity has emerged as a global health crisis, with its pathogenesis being closely linked to metabolic dysregulation in brown adipose tissue (BAT). However, the underlying mechanisms by which high-fat diets and environmental endocrine disr…

Investigation of the Effects of Bisphenol A and High-Fat Diet Co-Exposure on the Suppression of Insulin Signaling Molecule Expression and GLUT4 Translocation Leading to Insulin Resistance Open

Ze-Qi Lu, Min Cao, Junhu Zhang, Chunrun Qi, Bing Huang , et al. · 2025

Background/Objectives: Bisphenol A (BPA) is a pervasive environmental endocrine disruptor, and the lifestyle associated with a high-fat diet is becoming increasingly common. The precise relationship between these factors and the high incid…

Tumor-selective dye-based histological electrophoresis enables intraoperative tumor diagnosis via tumor-specific enhancement Open

Feiran Zhang, Jianing Cheng, Peng Xu, Chengbin Zhang, Limei Qu , et al. · 2025

Solid tissue biopsy is fundamental in guiding surgeons during intraoperative and peri-operative management of cancer patients. However, conventional histopathologic methods depend heavily on the expertise of trained pathologists, facing ch…

A H2-Releasing Bioreactor for Mitochondrial Rehabilitation in Infected Bone Defects Repair Open

Cin Kong, Chao Si, Haofeng Liu, Yawen Wang, J.W. Qiao , et al. · 2025

MF-YOLO: Mask Wearing Detection Algorithm for Dense Environments Open

Peng Wen, Zhengyi Yuan, Junhu Zhang, Haitao Li · 2025

To address the challenges of false positives and missed detections in face mask detection within dense environments, we propose the MF-YOLO face mask detection model. First, a feature map convolution approach is introduced to transform the…

Frontal Face Generation Based on Attitude Point Guidance and Attention Mechanism Improvement Open

Jihui Zhao, Zhengyi Yuan, Junhu Zhang, Haitao Li, Hui Li · 2024

The deflection of face angle is the most important factor affecting the accuracy in face recognition, non-frontal faces make some face recognition systems lose their due functions, the existing frontal face conversion methods often have th…

Identification of symptomatic carotid artery plaque: a predictive model combining angiography with optical coherence tomography Open

Jun Zhuo, Lin Wang, Ruolin Li, Zhiyuan Li, Junhu Zhang , et al. · 2024

Objective Symptomatic carotid artery disease is indicative of an elevated likelihood of experiencing a subsequent stroke, with the morphology of plaque and its specific features being closely linked to the risk of stroke occurrence. Our st…

Precise arraying of perovskite single crystals through droplet-assisted self-alignment Open

Jianglei Zhang, Yifan Yang, Weijun Li, Zigao Tang, Zhiying Hu , et al. · 2024

Patterned arrays of perovskite single crystals can avoid signal cross-talk in optoelectronic devices, while precise crystal distribution plays a crucial role in enhancing device performance and uniformity, optimizing photoelectric characte…

CCDC 2224700: Experimental Crystal Structure Determination Open

Wanting Pan, Yuhong He, Weijun Li, Lulu Liu, Keke Guo , et al. · 2024

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Cation-π interactions enabled water-stable perovskite X-ray flat mini-panel imager Open

Wanting Pan, Yuhong He, Weijun Li, Lulu Liu, Keke Guo , et al. · 2024

Sensitive and stable perovskite X-ray detectors are attractive in low-dosage medical examinations. The high sensitivity, tunable chemical compositions, electronic dimensions, and low-cost raw materials make perovskites promising next-gener…

Probing magnetoelectric effect in the spin-modulated magnet Fe<sub>2</sub>GeO<sub>4</sub> Open

G. Z. Zhou, Yongsen Tang, Lin Lin, Lin Huang, Junhu Zhang , et al. · 2023

The distinct spin amplitude wave was reported in a highly frustrated magnetic compound Fe 2 GeO 4 , which is very different from observations on other members of the M 2 GeO 4 (M = Fe, Co, and Ni) family, raising interest in this compound …

Knowledge‐guided digital twin modeling method of generating hierarchical scenes for a high‐speed railway Open

Heng Zhang, Wen Zhao, Zujie Han, Jun Zhu, Qing Zhu , et al. · 2023

China's railway construction is rapidly transitioning toward integrated management of “stakeholders, management elements, and management processes”. Therefore, comprehensive and whole‐process digital twin scene modeling is urgently needed …

Mask wearing object detection algorithm based on improved YOLOv5 Open

Peng Wen, Junhu Zhang, Haitao Li · 2023

Wearing a mask is one of the important measures to prevent infectious diseases. However, it is difficult to detect people's mask-wearing situation in public places with high traffic flow. To address the above problem, this paper proposes a…

Three-Dimensional Histological Electrophoresis for High-Throughput Cancer Margin Detection in Multiple Types of Tumor Specimens Open

Feiran Zhang, Jiajun Xu, Chengbin Zhang, Yin Li, Jiawei Gao , et al. · 2023

Accurate identification of tumor margins during cancer surgeries relies on a rapid detection technique that can perform high-throughput detection of multiple suspected tumor lesions at the same time. Unfortunately, the conventional histopa…

Well-ST-seq: cost-effective spatial transcriptomics at cellular level and high RNA capture efficiency Open

Nianzuo Yu, Zhengyang Jin, Chongyang Liang, Junhu Zhang, Bai Yang · 2023

Spatial transcriptomic technologies are promising tools to reveal fine anatomical profiles of tissues. As for the methodologies based on barcoded probe arrays, improving the balance among probe barcoding complexity and cost, gene capture s…

Three-dimensional histological electrophoresis enables fast automatic distinguishment of cancer margins and lymph node metastases Open

Feiran Zhang, Jiajun Xu, Ying Yue, Yajun Wang, Jianing Sun , et al. · 2023

Tissue diagnosis is important during surgical excision of solid tumors for margin evaluation. Conventional histopathologic methods rely heavily on image-based visual diagnosis by specialized pathologists, which can be time-consuming and su…

Exploiting synergistic effect of CO/NO gases for soft tissue transplantation using a hydrogel patch Open

Xiaoduo Tang, Jingyan Ren, Xin Wei, Tao Wang, Haiqiu Li , et al. · 2023

Autologous skin flap transplantation is a common method for repairing complex soft tissue defects caused by cancer, trauma, and congenital malformations. Limited blood supply range and post-transplantation ischemia-reperfusion injury can l…

NIR-II Imaging and Sandwiched Plasmonic Biosensor for Ultrasensitive Intraoperative Definition of Tumor-Invaded Lymph Nodes Open

Yajun Wang, Jingjie Nan, Huilong Ma, Jiajun Xu, Feifei Guo , et al. · 2023

Radical lymphadenectomy remains the cornerstone of preventing tumor metastasis through the lymphatic system. Current surgical resection of lymph nodes (LNs) based on fluorescence-guided surgery (FGS) suffers from low sensitivity/selectivit…

Tricyclic gyrase inhibitors Open

Daniel Bensen, Zhiyong Chen, John Finn, Thanh To Lam, Suk-Joong Lee , et al. · 2023

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions…

Sponge-Like, Semi-Interpenetrating Self-Sensory Hydrogel for Smart Photothermal-Responsive Soft Actuator with Biomimetic Self-Diagnostic Intelligence Open

Xingchen Cui, Zhezhi Liu, Bing Zhang, Xiaoduo Tang, Fuqiang Fan , et al. · 2023

Thickness-Sensing Sandwiched Plasmonic Biosensors Enable Label-Free Naked-Eye Antibody Quantification Open

Jingjie Nan, Weihong Sun, Xin Liu, Yuanyuan Che, Hongli Shan , et al. · 2022

Clinical serology assays for detecting the antibodies of the virus are time-consuming, are less sensitive/selective, or rely on sophisticated detection instruments. Here, we develop a sandwiched plasmonic biosensor (SPB) for supersensitive…

Thermal-annealing-regulated plasmonic enhanced fluorescence platform enables accurate detection of antigen/antibody against infectious diseases Open

Ying Yue, Jingjie Nan, Yuanyuan Che, Hongqin Xu, Weihong Sun , et al. · 2022

Supplementary material (UV-Vis absorption and transmission spectra of GNPs, SEM, microscopy and digital images of PEF platforms, and fluorescence images of IFMA on PEF platforms) is available in the online version of this article at 10.100…

Cross-amplified Barcodes on Slides for Spatial Transcriptomics Sequencing Open

Zhengyang Jin, Nianzuo Yu, Junda Bai, Zhiyi Liu, Hongrui Li , et al. · 2022

Spatial transcriptomics can reveal molecular signatures of tissue at spatial scales, but current technologies cannot integrate excellent accessibility and easy data-decoding. Here, we use oligonucleotides whose number is the square root of…

Exploiting Synergistic Effect of Controlled Co-Delivery Medicine for Soft Tissue Transplantation using Double System of Bio-Multifunctional Hydrogel Open

Xiaoduo Tang, Jingyan Ren, Xin Wei, Tao Wang, Yihan Sun , et al. · 2022

Autologous skin flap transplantation is a common method to repair complex soft tissue defects caused by cancer, trauma, and congenital malformations, among other conditions; however, limited blood supply range and post-transplantation isch…

Class-by-Class Sparse Representation Classification (Csrc) for Iris Recognition Open

Xiangyu Liu, Xiangyi Cui, Hui Li, Haitao Li, Junhu Zhang · 2022

Junhu Zhang YOU? Author Swipe