Junichi Furuta
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View article: Whole-genome sequencing reveals rare and structural variants contributing to psoriasis and identifies CERCAM as a risk gene
Whole-genome sequencing reveals rare and structural variants contributing to psoriasis and identifies CERCAM as a risk gene Open
Psoriasis vulgaris (PsV) is an immune-mediated inflammatory skin disorder with complex genetic architecture. Most genome-wide association studies (GWASs) of PsV have been limited to analyzing common single-nucleotide variants in Europeans,…
View article: Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2024
Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2024 Open
This is an abridged edition of English version of the Clinical Practice Guidelines for the Management of Atopic Dermatitis 2024. Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion. A cru…
View article: Blood DNA virome associates with autoimmune diseases and COVID-19
Blood DNA virome associates with autoimmune diseases and COVID-19 Open
View article: Case report: Ten cases of acquired idiopathic generalized anhidrosis treated with oral pilocarpine
Case report: Ten cases of acquired idiopathic generalized anhidrosis treated with oral pilocarpine Open
Acquired idiopathic generalized anhidrosis is a rare disease characterized by systemic anhidrosis or hypohidrosis without other systemic diseases. However, its etiology remains unclear. Autoimmune mechanisms seem to be involved in the deve…
View article: Enhancing evidence-informed policymaking in medicine and healthcare: stakeholder involvement in the Commons Project for rare diseases in Japan
Enhancing evidence-informed policymaking in medicine and healthcare: stakeholder involvement in the Commons Project for rare diseases in Japan Open
View article: A Case of Eosinophilic Pustular Folliculitis with Vegetating Lesions on the Lower Legs and Feet Resembling Pemphigus Vegetans
A Case of Eosinophilic Pustular Folliculitis with Vegetating Lesions on the Lower Legs and Feet Resembling Pemphigus Vegetans Open
is missing (Short communication)
View article: Supplementary Tables 1-3 from Silencing of <i>Peroxiredoxin 2</i> and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas
Supplementary Tables 1-3 from Silencing of <i>Peroxiredoxin 2</i> and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas Open
Supplementary Tables 1-3 from Silencing of Peroxiredoxin 2 and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas
View article: Data from Silencing of <i>Peroxiredoxin 2</i> and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas
Data from Silencing of <i>Peroxiredoxin 2</i> and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas Open
Aberrant methylation of promoter CpG islands (CGI) is involved in silencing of tumor suppressor genes and is also a potential cancer biomarker. Here, to identify CGIs aberrantly methylated in human melanomas, we did a genome-wide search us…
View article: Supplementary Tables 1-3 from Silencing of <i>Peroxiredoxin 2</i> and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas
Supplementary Tables 1-3 from Silencing of <i>Peroxiredoxin 2</i> and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas Open
Supplementary Tables 1-3 from Silencing of Peroxiredoxin 2 and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas
View article: Data from Silencing of <i>Peroxiredoxin 2</i> and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas
Data from Silencing of <i>Peroxiredoxin 2</i> and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas Open
Aberrant methylation of promoter CpG islands (CGI) is involved in silencing of tumor suppressor genes and is also a potential cancer biomarker. Here, to identify CGIs aberrantly methylated in human melanomas, we did a genome-wide search us…
View article: IL-10‒Producing Potency from Blood B Cells Correlates with the Prognosis of Alopecia Areata
IL-10‒Producing Potency from Blood B Cells Correlates with the Prognosis of Alopecia Areata Open
Cytotoxic IFN-γ‒producing T cells recognizing hair follicles are involved in the pathogenesis of alopecia areata (AA) (Xing et al., 2014Xing L. Dai Z. Jabbari A. Cerise J.E. Higgins C.A. Gong W. et al.Alopecia areata is driven by cytotoxic…
View article: Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2021
Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2021 Open
View article: Possible activation of effector B cells during drug‐induced hypersensitivity syndrome
Possible activation of effector B cells during drug‐induced hypersensitivity syndrome Open
Although the development of autoimmune disorders is recognized in drug‐induced hypersensitivity syndrome (DIHS), the serial change of B‐cell activity has not been well‐addressed. Herein, the serum levels of IL‐6, IL‐10, B‐cell activating f…
View article: Widespread involvement of purpura related to gastrointestinal involvements in adults with immunoglobulin A vasculitis
Widespread involvement of purpura related to gastrointestinal involvements in adults with immunoglobulin A vasculitis Open
Immunoglobulin A vasculitis (IgAV) is a type of vasculitis affecting small vessels with deposition of immune complexes consisting of IgA and complement component 3. IgAV involves the skin, gastrointestinal (GI) tract, joints, and kidneys. …
View article: Table of Contents
Table of Contents Open
View article: Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Regulates Epidermal Keratinization under Psoriatic Skin Inflammation
Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Regulates Epidermal Keratinization under Psoriatic Skin Inflammation Open
View article: HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy
HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy Open
View article: A case of cutaneous pseudolymphoma that presented with multiple large tumors on the upper back
A case of cutaneous pseudolymphoma that presented with multiple large tumors on the upper back Open
88歳，男性。初診の半年前から上背部に痒みあり。初診時，上背部正中に65×28 mmと28×22 mm大，右後腋窩に22×18mm大の紅色腫瘤を認めた。可溶性IL－2レセプター788 U/mL。病理組織学的には，真皮を主座として，一部皮下脂肪織に及ぶ稠密な細胞浸潤があり，リンパ濾胞構造なし。浸潤細胞は異型性に乏しいリンパ球様細胞で，多くは小型であり，中～大型細胞が混在した。免疫組織学的には，小型の細胞はCD3陽性細胞とCD20陽性細胞が混在し，中～大型細胞はCD20陽性，一…
View article: <b>2. Revision of Ethical Guidelines for Medical and Health Research for the purpose of responding to the revision of the Act on Protection of Personal Information</b>
<b>2. Revision of Ethical Guidelines for Medical and Health Research for the purpose of responding to the revision of the Act on Protection of Personal Information</b> Open
View article: Severe airflow obstruction in a patient with ulcerative colitis and toxic epidermal necrolysis: A case report
Severe airflow obstruction in a patient with ulcerative colitis and toxic epidermal necrolysis: A case report Open
Bronchiolitis is a rare condition mainly affecting the intralobular conducting and transitional small airways. The present study describes a case of severe airflow limitation in a patient with ulcerative colitis who developed toxic epiderm…