Jieyu He
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View article: Synthesis and Inhibitory Assessment of ACE2 Inhibitors for SARS-CoV-2: An <i>In Silico</i> and <i>In Vitro</i> Study
Synthesis and Inhibitory Assessment of ACE2 Inhibitors for SARS-CoV-2: An <i>In Silico</i> and <i>In Vitro</i> Study Open
The angiotensin-converting enzyme 2 (ACE2) is pivotal as the cellular receptor for SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), the virus responsible for COVID-19. This study presents a novel synthetic route for four analo…
View article: Twelve-month-old infants rationally attribute goals to inanimate objects
Twelve-month-old infants rationally attribute goals to inanimate objects Open
This study investigated whether infants use context-sensitive behavioral cues to view the movements of an inanimate object as goal-directed, and use this representation to predict its future behavior. Twelve-month-old infants (N = 48, 38 %…
View article: Short-term therapeutic efficacy analysis of drug-coated balloon combined with chocolate balloon for the treatment of femoropopliteal artery lesions
Short-term therapeutic efficacy analysis of drug-coated balloon combined with chocolate balloon for the treatment of femoropopliteal artery lesions Open
Background To report our experience of short-term results of drug-coated balloon (DCB) combined with chocolate balloon in the treatment of femoropopliteal artery lesions. Methods From June 2021 to December 2022, patients with femoropoplite…
View article: Risk factors of primary Sjögren<b>'</b>s syndrome combined with osteoporosis.
Risk factors of primary Sjögren<b>'</b>s syndrome combined with osteoporosis. Open
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease that is prevalent in middle-aged and elderly women, characterized by dry mouth, dry eyes, fatigue, and joint pain. Nearly one-third pSS patients have been suffering with ost…
View article: Icariin attenuates the calcification of vascular smooth muscle cells through <scp>ERα</scp> – <scp>p38MAPK</scp> pathway
Icariin attenuates the calcification of vascular smooth muscle cells through <span>ERα</span> – <span>p38MAPK</span> pathway Open
Objective To investigate the relationship between icariin and the osteoblastic differentiation of vascular smooth muscle cells (VSMCs) and the signal pathway involved. Methods We applied a universally accepted calcification model of VSMCs …
View article: Reply to Mahat, R.K.; Rathore, V. Comment on “Xiang et al. Association between the Triglyceride-Glucose Index and Vitamin D Status in Type 2 Diabetes Mellitus. Nutrients 2023, 15, 639”
Reply to Mahat, R.K.; Rathore, V. Comment on “Xiang et al. Association between the Triglyceride-Glucose Index and Vitamin D Status in Type 2 Diabetes Mellitus. Nutrients 2023, 15, 639” Open
We are pleased to see that Mahat and Rathore [...]
View article: Association between the Triglyceride-Glucose Index and Vitamin D Status in Type 2 Diabetes Mellitus
Association between the Triglyceride-Glucose Index and Vitamin D Status in Type 2 Diabetes Mellitus Open
Background: Vitamin D deficiency (VDD) increases the risk for type 2 diabetes mellitus (T2DM), which might be related to insulin resistance (IR). We aimed to explore the association between the triglyceride-glucose (TyG) index, a reliable …
View article: Vertical sleeve gastrectomy-derived gut metabolite licoricidin activates beige fat thermogenesis to combat obesity
Vertical sleeve gastrectomy-derived gut metabolite licoricidin activates beige fat thermogenesis to combat obesity Open
Obesity is a chronic metabolic disease, affecting individuals throughout the world. Bariatric surgery such as vertical sleeve gastrectomy (VSG) provides sustained weight loss and improves glucose homeostasis in obese mice and humans. Howev…
View article: Analysis of the relationship between serum alanine aminotransferase and body composition in Chinese women
Analysis of the relationship between serum alanine aminotransferase and body composition in Chinese women Open
Objective To investigate the relationships between serum alanine aminotransferase (ALT) and body composition among postmenopausal women in China. Methods A cross‐sectional study was conducted with 776 postmenopausal women in China from May…
View article: Exosomal MFGE8 from high glucose induced endothelial cells is involved in calcification/senescence of vascular smooth muscle cells
Exosomal MFGE8 from high glucose induced endothelial cells is involved in calcification/senescence of vascular smooth muscle cells Open
Vascular calcification/aging is a crucial feature of diabetic macro vasculopathy, resulting in serious cardiovascular diseases. The calcification/senescence of vascular smooth muscle cells (VSMCs) induced by hyperglycemia can cause diabeti…
View article: Dynamic Prognosis Model for Predicting Survival in Severe and Critically Ill COVID-19 Patients Using Machine Learning
Dynamic Prognosis Model for Predicting Survival in Severe and Critically Ill COVID-19 Patients Using Machine Learning Open
Background Novel coronavirus disease (COVID-19) is an emerging, rapidly evolving situation. At present, the prognosis of severe and critically ill patients has become an important focus of attention. We strived to develop a prognostic pred…
View article: Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice
Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice Open
Obesity is a global epidemic that is caused by excessive energy intake or inefficient energy expenditure. Brown or beige fat dissipates energy as heat through non-shivering thermogenesis by their high density of mitochondria. However, how …
View article: Adiponectin attenuates the premature senescence of vascular smooth muscle cells induced by high glucose through mTOR signaling pathway
Adiponectin attenuates the premature senescence of vascular smooth muscle cells induced by high glucose through mTOR signaling pathway Open
Objective Cardiovascular diseases and vascular aging are common in patients with diabetes. High glucose is a major cause of vascular aging and cardiovascular diseases. Premature senescence of vascular smooth muscle cells (VSMCs) is one of …
View article: Comment on the intravenous tranexamic acid use in revision total joint arthroplasty
Comment on the intravenous tranexamic acid use in revision total joint arthroplasty Open
Jieyu He, Youshuo Liu Department of Geriatrics, Second Xiangya Hospital, Central South University, Changsha 410011, China Kuo et al thoroughly evaluated the safety and efficacy of intravenous tranexamic acid in revision total joi…
View article: The analysis of correlation between frailty index and postoperative complications of aged patients with nodular goiter
The analysis of correlation between frailty index and postoperative complications of aged patients with nodular goiter Open
Objective To explore the correlation between frailty index (FI) and postoperative complications of aged patients with nodular goiter (NG). Methods A total of 120 aged patients with NG undergoing operative treatment from May 2013 to October…
View article: Sarco-Osteoporosis: Prevalence and Association with Frailty in Chinese Community-Dwelling Older Adults
Sarco-Osteoporosis: Prevalence and Association with Frailty in Chinese Community-Dwelling Older Adults Open
The aim was to apply AWGS criteria to estimate the prevalence of sarco-osteoporosis and investigate its relationship with frailty, in a sample of 316 community-dwelling Chinese older people. Regression analysis was performed using frailty …