Junji Koyama
YOU?
Author Swipe
View article: Artificial intelligence-based personalized survival prediction using clinical and radiomics features in patients with advanced non-small cell lung cancer
Artificial intelligence-based personalized survival prediction using clinical and radiomics features in patients with advanced non-small cell lung cancer Open
View article: Comparison of immune checkpoint inhibitor plus chemotherapy or ipilimumab plus nivolumab-based therapy for NSCLC patients with PD-L1 TPS (1–49 %): TOPGAN2023-01
Comparison of immune checkpoint inhibitor plus chemotherapy or ipilimumab plus nivolumab-based therapy for NSCLC patients with PD-L1 TPS (1–49 %): TOPGAN2023-01 Open
Among PD-L1 TPS 1-49 %, there was no significant difference in survival outcomes between the ICI-chemo group and the I-N-based therapy group. Based on the results of a subgroup analysis, ICI-chemo may be superior for treating NSCLC with a …
View article: Postoperative Symptomatic Cerebral Vasospasm: Requiring Attention Following an Uneventful Resection of an Epidermoid Cyst - A Case Report and Literature Review
Postoperative Symptomatic Cerebral Vasospasm: Requiring Attention Following an Uneventful Resection of an Epidermoid Cyst - A Case Report and Literature Review Open
Cerebral vasospasm associated with epidermoid cyst can be caused by tumor content spillage, such as spontaneous rupture and postsurgical resection. Symptomatic cerebral vasospasm following the resection of an intracranial epidermoid cyst i…
View article: Prevalence and Severity of Positional Posterior Plagiocephaly and Positional Posterior Brachycephaly in Children and Adolescents in Japan
Prevalence and Severity of Positional Posterior Plagiocephaly and Positional Posterior Brachycephaly in Children and Adolescents in Japan Open
This study aimed to assess the prevalence, severity, and natural history of positional posterior plagiocephaly (PPP) and positional posterior brachycephaly in Japan. We conducted a cross-sectional study of pediatric patients, ranging from …
View article: Femoral bone metastasis is a poor prognostic factor in osimertinib-treated patients with EGFR-mutated non-small cell lung cancer: a retrospective, multicenter study
Femoral bone metastasis is a poor prognostic factor in osimertinib-treated patients with EGFR-mutated non-small cell lung cancer: a retrospective, multicenter study Open
Background: Epidermal growth factor receptor ( EGFR )-mutant non-small cell lung cancer (NSCLC) have higher frequency of bone metastases than those of wild type; however, the metastatic pattern and the influence on clinical outcome remains…
View article: Femoral bone metastasis is a poor prognostic factor in EGFR-TKIs-treated patients with <i>EGFR</i>-mutated non-small-cell lung cancer: a retrospective, multicenter cohort study
Femoral bone metastasis is a poor prognostic factor in EGFR-TKIs-treated patients with <i>EGFR</i>-mutated non-small-cell lung cancer: a retrospective, multicenter cohort study Open
Background: Epidermal growth factor receptor ( EGFR)-mutant non-small-cell lung cancers (NSCLCs) have higher frequencies of bone metastases than those of wild type; however, the metastatic pattern and influence on clinical outcome remain u…
View article: Efficacy and safety of second-line therapy of docetaxel plus ramucirumab after first-line platinum-based chemotherapy plus immune checkpoint inhibitors in non-small cell lung cancer (SCORPION): a multicenter, open-label, single-arm, phase 2 trial
Efficacy and safety of second-line therapy of docetaxel plus ramucirumab after first-line platinum-based chemotherapy plus immune checkpoint inhibitors in non-small cell lung cancer (SCORPION): a multicenter, open-label, single-arm, phase 2 trial Open
View article: EP11.03-32 Dose the Histological Subtype of NSCC-NOS Affect the Efficacy of 1st-Line PD-1/PD-L1 Inhibitors with or without Chemotherapy?
EP11.03-32 Dose the Histological Subtype of NSCC-NOS Affect the Efficacy of 1st-Line PD-1/PD-L1 Inhibitors with or without Chemotherapy? Open
View article: Femoral bone metastasis is a poor prognostic factor in osimertinib-treated patients with EGFR-mutated non-small cell lung cancer
Femoral bone metastasis is a poor prognostic factor in osimertinib-treated patients with EGFR-mutated non-small cell lung cancer Open
Objectives: Epidermal growth factor receptor ( EGFR )-mutant non-small cell lung cancer (NSCLC) have higher frequency of bone metastases than those of wild type; however, the metastatic pattern and the influence on clinical outcome remains…
View article: Second-line immunosuppressant administration for steroid-refractory immune-related adverse events in patients with lung cancer
Second-line immunosuppressant administration for steroid-refractory immune-related adverse events in patients with lung cancer Open
View article: Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategies
Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategies Open
Currently, immune checkpoint inhibitors (ICIs) are widely considered the standard initial treatment for advanced non-small cell lung cancer (NSCLC) when there are no targetable driver oncogenic alternations. NSCLC tumors that have two alte…
View article: Focal glioneuronal differentiation in an atypical teratoid/rhabdoid tumor after chemoradiotherapy
Focal glioneuronal differentiation in an atypical teratoid/rhabdoid tumor after chemoradiotherapy Open
View article: Treatment optimization by monitoring vancomycin concentration in the serum and cerebrospinal fluid in a child with cystoperitoneal shunt-related infection caused by methicillin-resistant Staphylococcus aureus: a case report and literature review
Treatment optimization by monitoring vancomycin concentration in the serum and cerebrospinal fluid in a child with cystoperitoneal shunt-related infection caused by methicillin-resistant Staphylococcus aureus: a case report and literature review Open
Background Cerebral ventricular shunt infections caused by methicillin-resistant Staphylococcus aureus (MRSA), especially strains with elevated minimum inhibitory concentration (MIC) values, have a poor prognosis. Monitoring serum vancomyc…
View article: Cerebral venous sinus thrombosis after a third dose of mRNA COVID‐19 vaccine in an adolescent
Cerebral venous sinus thrombosis after a third dose of mRNA COVID‐19 vaccine in an adolescent Open
Since the first reports in 2019, coronavirus disease 2019 (COVID-19) has spread worldwide, resulting in rapid production of several effective vaccines. The Pfizer-BioNTech and Moderna vaccines are both messenger ribonucleic acid (mRNA)-bas…
View article: Treatment Optimization by Monitoring Vancomycin Concentration in the Serum and Cerebrospinal Fluid in a Child with Cystoperitoneal Shunt-related Infection Caused by Methicillin-resistant Staphylococcus aureus: A case report
Treatment Optimization by Monitoring Vancomycin Concentration in the Serum and Cerebrospinal Fluid in a Child with Cystoperitoneal Shunt-related Infection Caused by Methicillin-resistant Staphylococcus aureus: A case report Open
Background Cerebral ventricular shunt infections caused by methicillin-resistant Staphylococcus aureus (MRSA), especially strains with elevated minimal inhibitory concentration (MIC) values, have a poor prognosis. Monitoring serum vancomyc…
View article: Cerebral Venous Sinus Thrombosis After a Third Dose of mRNA COVID-19 Vaccine in an Adolescent: A case report
Cerebral Venous Sinus Thrombosis After a Third Dose of mRNA COVID-19 Vaccine in an Adolescent: A case report Open
Background : Several effective vaccines against Coronavirus disease 2019 (COVID-19) have been developed to control the spread of the disease. A few cases of thrombosis have been reported post-vaccination, especially among young adult women…
View article: COT-13 OUTCOMES OF MEDULLOBLASTOMA IN KOBE CHILDREN,S HOSPITAL OVER THE RECENT 11 YEARS
COT-13 OUTCOMES OF MEDULLOBLASTOMA IN KOBE CHILDREN,S HOSPITAL OVER THE RECENT 11 YEARS Open
Introduction Medulloblastoma is the most frequent malignant brain tumor in children, which 5-year survival rate have improved to 70-85%. In this study, we retrospectively reviewed outcomes and late complications of 31 medulloblastoma cases…
View article: COT-14 OUTCOMES OF MEDULLOBLASTOMA IN KOBE CHILDREN,S HOSPITAL OVER THE RECENT 11 YEARS
COT-14 OUTCOMES OF MEDULLOBLASTOMA IN KOBE CHILDREN,S HOSPITAL OVER THE RECENT 11 YEARS Open
Introduction Medulloblastoma is the most frequent malignant brain tumor in children, which 5-year survival rate have improved to 70-85%. In this study, we retrospectively reviewed outcomes and late complications of 31 medulloblastoma cases…
View article: Clinical efficacy of amrubicin in patients with small cell lung cancer relapse after first‐line treatment including immune checkpoint inhibitors: A retrospective multicenter study (<scp>TOPGAN</scp> 2021‐01)
Clinical efficacy of amrubicin in patients with small cell lung cancer relapse after first‐line treatment including immune checkpoint inhibitors: A retrospective multicenter study (<span>TOPGAN</span> 2021‐01) Open
Background The therapeutic efficacy of cytotoxic anticancer drugs has been reported to be enhanced after immune checkpoint inhibitors (ICI) in non–small cell lung cancer; however, it is unclear whether the same is applicable for small cell…
View article: Symptomatic vasospasm after resection of an intracranial epidermoid cyst: A case report
Symptomatic vasospasm after resection of an intracranial epidermoid cyst: A case report Open
We report a 10-year-old girl who developed symptomatic vasospasm after complete resection of a left cerebellopontine angle epidermoid cyst. Conservative management with intravenous hydration and administration of a corticosteroid and free …
View article: Endovascular Treatment of Tandem Atherosclerotic Cervical Internal Carotid Artery Occlusion in the Setting of Acute Ischemic Stroke
Endovascular Treatment of Tandem Atherosclerotic Cervical Internal Carotid Artery Occlusion in the Setting of Acute Ischemic Stroke Open
Background Among tandem occlusions, atherosclerotic cervical internal carotid artery occlusion (ACICAO) can be technically challenging and associated with its unique complications. We evaluated our experience with endovascular treatment (E…
View article: Non-invasive early prediction of immune checkpoint inhibitor efficacy in non-small-cell lung cancer patients using on-treatment serum CRP and NLR
Non-invasive early prediction of immune checkpoint inhibitor efficacy in non-small-cell lung cancer patients using on-treatment serum CRP and NLR Open
View article: Non-invasive early prediction of Immune Checkpoint Inhibitor efficacy in Non-Small Cell Lung Cancer patients using on-treatment serum CRP and NLR
Non-invasive early prediction of Immune Checkpoint Inhibitor efficacy in Non-Small Cell Lung Cancer patients using on-treatment serum CRP and NLR Open
Purpose We determined the clinical relevance of early C-reactive protein (CRP) and neutrophil-lymphocyte ratio (NLR) change in blood as surrogate markers of pro-tumor inflammation (PTI) for predicting clinical outcome of programmed cell de…
View article: Epidural Spinal Cord Compression as the Presenting Manifestation of Acute Myeloid Leukemia: A Case Report and Literature Review
Epidural Spinal Cord Compression as the Presenting Manifestation of Acute Myeloid Leukemia: A Case Report and Literature Review Open
We herein report a rare case of spinal cord compression due to epidural involvement of acute myeloid leukemia (AML). A 14-year-old boy presented with a 7-day history of back pain, paraplegia and hypoesthesia. Contrast-enhanced computed tom…
View article: Clinical efficacy of osimertinib in EGFR-mutant non-small cell lung cancer with distant metastasis
Clinical efficacy of osimertinib in EGFR-mutant non-small cell lung cancer with distant metastasis Open
View article: Clinical efficacy of osimertinib in EGFR-mutant non-small cell lung cancer with distant metastasis
Clinical efficacy of osimertinib in EGFR-mutant non-small cell lung cancer with distant metastasis Open
Background: Osimertinib—the third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)—has been widely used as a first-line treatment for patients with metastatic EGFR -mutant non-small cell lung cancer (NSCLC…
View article: Additional file 2 of Clinical efficacy of osimertinib in EGFR-mutant non-small cell lung cancer with distant metastasis
Additional file 2 of Clinical efficacy of osimertinib in EGFR-mutant non-small cell lung cancer with distant metastasis Open
Additional file 2. Supplementary data.
View article: Cerebral Venous Sinus Thrombosis after a Third Dose of mRNA COVID-19 Vaccine in an Adolescent
Cerebral Venous Sinus Thrombosis after a Third Dose of mRNA COVID-19 Vaccine in an Adolescent Open
View article: BT-4 The treatment history of long-term survivors of Optic Pathway Glioma in Kobe Children’s Hospital
BT-4 The treatment history of long-term survivors of Optic Pathway Glioma in Kobe Children’s Hospital Open
Optic pathway glioma(OPG) is almost recognized in childhood and about 0.01–0.02% of whole brain tumor in Japan. Because of the rare tumor, there are few reports about results of its treatment. In 2021, Guideline of Optic pathway/hypothalam…
View article: Is area under the curve the best parameter for carboplatin induced emetic risk stratification?
Is area under the curve the best parameter for carboplatin induced emetic risk stratification? Open
Carboplatin (CBDCA)-induced emetic risk is currently classified on the basis of CBDCA-area under the curve (CBDCA-AUC). We investigated the utility of three CBDCA dosage parameters for predicting emesis by CBDCA. Patients with thoracic can…