Jun‐Jie Yin
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View article: Differentiating network structures and sex differences of pain-related outcomes, analgesic opioid dosages, and psychosocial factors for postoperative management: a study of PAIN OUT registry in seven Asian regions
Differentiating network structures and sex differences of pain-related outcomes, analgesic opioid dosages, and psychosocial factors for postoperative management: a study of PAIN OUT registry in seven Asian regions Open
Background Despite advancements in global healthcare, Asia lacks a systematic framework for postoperative pain-related symptoms, particularly in addressing pain identification/prevention and reporting sex differences. This study used netwo…
View article: Integration of Network Pharmacology, Molecular Docking, and Experimental Validation to Identify the Effect of EGCG on Alleviating Chondrocyte Inflammatory Damage by Targeting ER Stress-STAT3 Crosstalk
Integration of Network Pharmacology, Molecular Docking, and Experimental Validation to Identify the Effect of EGCG on Alleviating Chondrocyte Inflammatory Damage by Targeting ER Stress-STAT3 Crosstalk Open
This study reveals that EGCG may ameliorate the metabolic imbalance of extracellular matrix (ECM) and inflammatory responses by modulating the activity of the ER stress-STAT3 crosstalk.
View article: Ligand-Engineered Mn-MOFs Derived Mn2O3 for Enhanced Carbon Dioxide Conversion to Ethylene Urea
Ligand-Engineered Mn-MOFs Derived Mn2O3 for Enhanced Carbon Dioxide Conversion to Ethylene Urea Open
The utilization of carbon dioxide (CO2) for synthesizing value-added chemicals represents a promising environmentally sustainable strategy. Herein, we synthesized a series of Mn2O3 catalysts derived from metal-organic frameworks (MOFs) inc…
View article: Fingerprinting Organic Molecules for the Inverse Design of Two-Dimensional Hybrid Perovskites with Target Energetics
Fingerprinting Organic Molecules for the Inverse Design of Two-Dimensional Hybrid Perovskites with Target Energetics Open
Artificial intelligence (AI)-assisted workflows have transformed materials discovery, enabling rapid exploration of chemical spaces of functional materials. Endowed with extraordinary optoelectronic properties, two-dimensional (2D) hybrid …
View article: Hepatic metastasis of pulmonary large cell neuroendocrine carcinoma: A case report and literature review
Hepatic metastasis of pulmonary large cell neuroendocrine carcinoma: A case report and literature review Open
Large cell neuroendocrine carcinoma of the lung is a rare and aggressive malignancy with a high propensity for metastasis. This carcinoma demonstrates a significantly higher propensity for hepatic metastasis compared with other non-small c…
View article: Bergenin Alleviates Myocardial Ischemia/Reperfusion Injury via Regulating SIRT1 Through Ferroptosis
Bergenin Alleviates Myocardial Ischemia/Reperfusion Injury via Regulating SIRT1 Through Ferroptosis Open
Bergenin exerted a protective effect on the myocardium by modulating the ferroptosis process during myocardial I/R injury through the SIRT1/AMPK/PGC-1α pathway.
View article: Exceptional CO<sub>2</sub> Hydrogenation to Ethanol via Precise Single‐Atom Ir Deposition on Functional P Islands
Exceptional CO<sub>2</sub> Hydrogenation to Ethanol via Precise Single‐Atom Ir Deposition on Functional P Islands Open
The thermocatalytic hydrogenation of CO 2 to ethanol has attracted significant interest because ethanol offers ease of transport and substantial value in chemical synthesis. Here, we present a state‐of‐the‐art catalyst for the CO 2 hydroge…
View article: Primary hepatic epithelioid hemangioendothelioma: a case report
Primary hepatic epithelioid hemangioendothelioma: a case report Open
Epithelioid hemangioendothelioma is a low-grade malignant tumor of vascular origin. The rarity of hepatic epithelioid hemangioendothelioma (HEHE) makes the diagnosis and treatment of this entity challenging. We report a case of a 69-year-o…
View article: Strength and Sensitivity of Land-Atmosphere Interaction
Strength and Sensitivity of Land-Atmosphere Interaction Open
The land-atmosphere coupling strength has been defined as the percentage of precipitation variability explained by the variation of soil moisture in the Global Land-Atmosphere Coupling Experiment (GLACE). While it is useful to identify glo…
View article: CircZCCHC2 (hsa_circ_0000854) promotes hepatocellular carcinoma progression through modulating miR-936/BTBD7 axis and activating Rho/ROCK2 pathway
CircZCCHC2 (hsa_circ_0000854) promotes hepatocellular carcinoma progression through modulating miR-936/BTBD7 axis and activating Rho/ROCK2 pathway Open
Hepatocellular carcinoma (HCC) is one of the most aggressive and refractory cancers due to its high propensity to metastasize and the unavailability of efficacious treatments. Circular RNAs (circRNAs) participate in diverse biological acti…
View article: Multi-omic profiling reveals discrepant immunogenic properties and a unique tumor microenvironment among melanoma brain metastases
Multi-omic profiling reveals discrepant immunogenic properties and a unique tumor microenvironment among melanoma brain metastases Open
Melanoma brain metastases (MBM) are clinically challenging to treat and exhibit variable responses to immune checkpoint therapies. Prior research suggests that MBM exhibit poor tumor immune responses and are enriched in oxidative phosphory…
View article: CCDC 2267214: Experimental Crystal Structure Determination
CCDC 2267214: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2267609: Experimental Crystal Structure Determination
CCDC 2267609: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Application of Synthetic DINCAE–BME Spatiotemporal Interpolation Framework to Reconstruct Chlorophyll–a from Satellite Observations in the Arabian Sea
Application of Synthetic DINCAE–BME Spatiotemporal Interpolation Framework to Reconstruct Chlorophyll–a from Satellite Observations in the Arabian Sea Open
Chlorophyll–a (Chl–a) concentration is an indicator of phytoplankton pigment, which is associated with the health of marine ecosystems. A commonly used method for the determination of Chl–a is satellite remote sensing. However, due to clou…
View article: The Glycosylation of Immune Checkpoints and Their Applications in Oncology
The Glycosylation of Immune Checkpoints and Their Applications in Oncology Open
Tumor therapies have entered the immunotherapy era. Immune checkpoint inhibitors have achieved tremendous success, with some patients achieving long-term tumor control. Tumors, on the other hand, can still accomplish immune evasion, which …
View article: Characterization of MET Exon 14 Skipping Alterations (in NSCLC) and Identification of Potential Therapeutic Targets Using Whole Transcriptome Sequencing
Characterization of MET Exon 14 Skipping Alterations (in NSCLC) and Identification of Potential Therapeutic Targets Using Whole Transcriptome Sequencing Open
METex14 splicing alterations and MET co-amplification translated to higher and synergistic MET expression at the transcriptomic level. High frequencies of MDM2 and CDK4 co-amplifications and association with multiple immunosuppressive chec…
View article: Management of pancreatic walled-off necrosis using an ultrasonic pneumatic lithotripsy system and double-catheter aspirated lavage performed through drainage tract: a case report
Management of pancreatic walled-off necrosis using an ultrasonic pneumatic lithotripsy system and double-catheter aspirated lavage performed through drainage tract: a case report Open
Patients with pancreatic walled-off necrosis (WON) treated by minimally invasive approaches often require repeated necrosectomy instead of conventional open necrosectomy. A 55-year-old woman with lateral infected pancreatic WON was success…