Junjun She
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View article: Engineered resveratrol nanoantioxidants: intestinal targeted oral delivery system of mesalazine for inflammatory bowel disease via spatiotemporal-ecological regulation
Engineered resveratrol nanoantioxidants: intestinal targeted oral delivery system of mesalazine for inflammatory bowel disease via spatiotemporal-ecological regulation Open
Inflammatory bowel disease (IBD) is a life-threatening condition associated with excessive reactive oxygen species (ROS), chronic mucosal inflammation, and gut microbiota dysbiosis. The therapeutic potential of resveratrol (Rv) and mesalaz…
View article: Recurrence outcomes of robotic versus laparoscopic surgery for gastric cancer: A multicenter study
Recurrence outcomes of robotic versus laparoscopic surgery for gastric cancer: A multicenter study Open
View article: Sustained circulation of Aedes albopictus-derived novel almendraviruses in the urban parks
Sustained circulation of Aedes albopictus-derived novel almendraviruses in the urban parks Open
View article: Validated nomograms for non-metastatic colorectal cancer prognosis prediction: a population-based study
Validated nomograms for non-metastatic colorectal cancer prognosis prediction: a population-based study Open
Introduction The TNM staging system has limitations in predicting prognosis for colorectal cancer (CRC). This study aimed to develop and validate a nomogram incorporating the albumin-derived neutrophil-to-lymphocyte ratio (Alb-dNLR) score,…
View article: Indirect ELISAs Based on Nipah and Langya Virus Proteins for Detecting Antibodies in Animals
Indirect ELISAs Based on Nipah and Langya Virus Proteins for Detecting Antibodies in Animals Open
Nipah virus (NiV) and Langya virus (LayV) are emerging zoonotic henipaviruses with serious public health risks. However, no vaccine or drug is available for either disease. To address the persistent threats posed by NiV and LayV, we prelim…
View article: Unraveling the role of distinct cytoskeletal motility structures in Mycoplasma pneumoniae relatives
Unraveling the role of distinct cytoskeletal motility structures in Mycoplasma pneumoniae relatives Open
View article: Correction: Qiu et al. P53 Deficiency Accelerates Esophageal Epithelium Intestinal Metaplasia Malignancy. Biomedicines 2023, 11, 882
Correction: Qiu et al. P53 Deficiency Accelerates Esophageal Epithelium Intestinal Metaplasia Malignancy. Biomedicines 2023, 11, 882 Open
In the original publication [...]
View article: Assessment of robotic versus laparoscopic gastrectomy for gastric cancer patients with intraoperative technical complexity: a multicenter retrospective study
Assessment of robotic versus laparoscopic gastrectomy for gastric cancer patients with intraoperative technical complexity: a multicenter retrospective study Open
Background: While robotic gastrectomy (RG) is increasingly used in gastric cancer surgery, its potential advantages over laparoscopic gastrectomy (LG) in intraoperative technical complexity (ITC) cases remain debated. Methods: This retrosp…
View article: Clinical outcomes and cost-effectiveness analysis of robotic and endoscopic cooperative surgery for treating gastric submucosal tumors: a longitudinal nested cohort study
Clinical outcomes and cost-effectiveness analysis of robotic and endoscopic cooperative surgery for treating gastric submucosal tumors: a longitudinal nested cohort study Open
RECS is a safe and effective method for treating GSMTs, offering faster postoperative recovery and fewer gastrointestinal symptoms than laparoscopic and open surgeries. Despite the increased costs associated with the introduction of RECS t…
View article: Extrachromosomal circular DNA as a novel biomarker for the progression of colorectal cancer
Extrachromosomal circular DNA as a novel biomarker for the progression of colorectal cancer Open
View article: Low transthyretin is associated with the poor prognosis of colorectal cancer
Low transthyretin is associated with the poor prognosis of colorectal cancer Open
Objective To determine whether transthyretin (TTR) influences the prognosis of patients with colorectal cancers and establish a predictive model based on TTR. Methods Between January 2013 and February 2019, the clinical data of 1322 CRC pa…
View article: Association between 5-item modified frailty index and clinical outcomes in elderly rectal cancer patients after radical surgery
Association between 5-item modified frailty index and clinical outcomes in elderly rectal cancer patients after radical surgery Open
View article: An optimal dynamic treatment regime estimator for indefinite-horizon survival outcomes
An optimal dynamic treatment regime estimator for indefinite-horizon survival outcomes Open
We propose a new method in indefinite-horizon settings for estimating optimal dynamic treatment regimes for time-to-event outcomes. This method allows patients to have different numbers of treatment stages and is constructed using generali…
View article: Infinite Coordination Polymer Polydopamine Nanocomposites Dual‐Pathway Multistep Induction of Long‐Term Hyperimmunity Combined With Photothermal‐Chemo Synergistic Therapy Colorectal Cancer
Infinite Coordination Polymer Polydopamine Nanocomposites Dual‐Pathway Multistep Induction of Long‐Term Hyperimmunity Combined With Photothermal‐Chemo Synergistic Therapy Colorectal Cancer Open
To improve the long‐term therapeutic efficacy of colorectal cancer, we propose a synergistic treatment strategy involving dual‐pathway, multistep induction of long‐term hyperimmunity combined with photothermal‐chemotherapy. To implement th…
View article: Comparison of Short- and Long-Term Outcomes of Robotic Versus Laparoscopic Gastrectomy for cT4a Gastric Cancer: A Multicenter Cohort Study
Comparison of Short- and Long-Term Outcomes of Robotic Versus Laparoscopic Gastrectomy for cT4a Gastric Cancer: A Multicenter Cohort Study Open
View article: Recurrence Outcomes of Robotic Versus Laparoscopic Surgery for Gastric Cancer: A Multicenter Study
Recurrence Outcomes of Robotic Versus Laparoscopic Surgery for Gastric Cancer: A Multicenter Study Open
View article: Corrigendum to 'One-pot synthesis of chlorhexidine-templated biodegradable mesoporous organosilica nanoantiseptics' [Colloid. Surf. B: Biointerfaces 187(2019)110653]
Corrigendum to 'One-pot synthesis of chlorhexidine-templated biodegradable mesoporous organosilica nanoantiseptics' [Colloid. Surf. B: Biointerfaces 187(2019)110653] Open
View article: Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy
Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy Open
While cell fate determination and maintenance are important in establishing and preserving tissue identity and function during development, aberrant cell fate transition leads to cancer cell heterogeneity and resistance to treatment. Here,…
View article: The effect of 5-item modified frailty index on clinical outcomes in elderly rectal cancer patients after curative surgery
The effect of 5-item modified frailty index on clinical outcomes in elderly rectal cancer patients after curative surgery Open
Frailty is a significant factor contributing to an increased risk of adverse clinical outcomes in older cancer patients. This study aims to investigate the impact of the 5-item modified frailty index (mFI) on both short-term and long-term …
View article: The association of appendectomy with prognosis and tumor-associated macrophages in patients with colorectal cancer
The association of appendectomy with prognosis and tumor-associated macrophages in patients with colorectal cancer Open
View article: Appendix removal affects the subsequent cancer risk in Asian adults: A territory-wide population-based cohort study
Appendix removal affects the subsequent cancer risk in Asian adults: A territory-wide population-based cohort study Open
Human appendix is critical for the maintenance of intestinal homeostasis. Appendicectomy has been the optimal treatment of acute appendicitis, yet the cancer incidence after appendix removal remains unclear. In this territory-wide retrospe…
View article: MGMT activated by Wnt pathway promotes cisplatin tolerance through inducing slow-cycling cells and nonhomologous end joining in colorectal cancer
MGMT activated by Wnt pathway promotes cisplatin tolerance through inducing slow-cycling cells and nonhomologous end joining in colorectal cancer Open
View article: The effect of robotic surgery on low anterior resection syndrome in patients with lower rectal cancer: a propensity score-matched analysis
The effect of robotic surgery on low anterior resection syndrome in patients with lower rectal cancer: a propensity score-matched analysis Open
View article: Establish a novel tumor budding-related signature to predict prognosis and guide clinical therapy in colorectal cancer
Establish a novel tumor budding-related signature to predict prognosis and guide clinical therapy in colorectal cancer Open
View article: Defining the biogeographical map and potential bacterial translocation of microbiome in human ‘surface organs’
Defining the biogeographical map and potential bacterial translocation of microbiome in human ‘surface organs’ Open
View article: PLOD3 facilitated T cell activation in the colorectal tumor microenvironment and liver metastasis by the TNF-α/ NF-κB pathway
PLOD3 facilitated T cell activation in the colorectal tumor microenvironment and liver metastasis by the TNF-α/ NF-κB pathway Open
Background Colorectal cancer (CRC) has been the third most prevalent cancer worldwide. Liver metastasis is the critical factor for the poor prognosis of CRC. Here, we investigated the expression and role of PLOD3 in CRC. Methods Different …
View article: PacBio sequencing of human fecal samples uncovers the DNA methylation landscape of 22 673 gut phages
PacBio sequencing of human fecal samples uncovers the DNA methylation landscape of 22 673 gut phages Open
Gut phages have an important impact on human health. Methylation plays key roles in DNA recognition, gene expression regulation and replication for phages. However, the DNA methylation landscape of gut phages is largely unknown. Here, with…
View article: Establish a novel tumor budding-related signature to predict prognosis and guide clinical therapy in colorectal cancer
Establish a novel tumor budding-related signature to predict prognosis and guide clinical therapy in colorectal cancer Open
Tumor budding is a long-established independent adverse prognostic marker for colorectal cancer (CRC), yet assessment of tumor budding was not reproducible. Therefore, development of precise diagnostic approaches to tumor budding is in dem…
View article: Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy
Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy Open
While cell fate determination and maintenance are important in establishing and preserving tissue identity and function during development, aberrant cell fate transition leads to cancer cell heterogeneity and resistance to treatment. Here,…
View article: Real-world analysis of survival benefit of surgery and adjuvant therapy in elderly patients with colorectal cancer
Real-world analysis of survival benefit of surgery and adjuvant therapy in elderly patients with colorectal cancer Open