Jun Tao
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View article: Isolation, Identification, and Comprehensive Genomic Characterization of a Bovine Rotavirus G10P[11] Strain in China
Isolation, Identification, and Comprehensive Genomic Characterization of a Bovine Rotavirus G10P[11] Strain in China Open
Rotavirus is a principal infectious agent of diarrhea in both animals and humans, causing acute gastroenteritis with symptoms such as abdominal pain, fever, nausea, and vomiting. Bovine rotavirus (BRVA) not only causes illness in cattle bu…
View article: Diabetes is associated with impaired skeletal muscle quality, not quantity, in older adults, based on CT-derived chest muscle metrics
Diabetes is associated with impaired skeletal muscle quality, not quantity, in older adults, based on CT-derived chest muscle metrics Open
View article: Risk of lymphoma among people with HIV in the United States, 2001-2019
Risk of lymphoma among people with HIV in the United States, 2001-2019 Open
Background Lymphomas are among the most common malignancies in people with HIV. Although the widespread use of combination antiretroviral therapy has substantially reduced the risk of lymphoma among people with HIV, data on specific lympho…
View article: The association of calf circumference with nutritional risk and mortality in type 2 diabetes aged over 80 years inpatient Chinese
The association of calf circumference with nutritional risk and mortality in type 2 diabetes aged over 80 years inpatient Chinese Open
Objective The aim of this study was to determine whether low calf circumference (CC) could predict nutritional risk and the cut-off value of CC in type 2 diabetes (T2D) older patients. We also aimed to evaluate the risk factors for predict…
View article: Suboptimal Quality of Health Care and Associated Socioeconomic Factors Among Cancer Survivors During the COVID-19 Pandemic: A Cross-Sectional Study
Suboptimal Quality of Health Care and Associated Socioeconomic Factors Among Cancer Survivors During the COVID-19 Pandemic: A Cross-Sectional Study Open
We described disruptions in cancer-related healthcare appointments and perceived quality of healthcare during the COVID-19 pandemic and identified predictors, including socioeconomic factors, of perceived quality of healthcare among cancer…
View article: M1 Macrophage is a Novel Potential Trigger for Endothelial Senescence: Role of Exosomal miR‐155 Targeting SOCS1 Signal
M1 Macrophage is a Novel Potential Trigger for Endothelial Senescence: Role of Exosomal miR‐155 Targeting SOCS1 Signal Open
Age‐related proinflammatory microenvironment induced by infiltration of M1 macrophages promotes endothelial senescence‐mediated vascular diseases. Macrophages exert their immunomodulatory effects by releasing exosomes. However, the underly…
View article: The chest CT perspective on sarcopenia: Exploring reference values for muscle mass quantity/quality and its application in elderly adults
The chest CT perspective on sarcopenia: Exploring reference values for muscle mass quantity/quality and its application in elderly adults Open
This study established reference values for sarcopenia diagnosis through chest CT scans among the Chinese population, highlighting the importance of utilizing chest CT scans for sarcopenia detection and muscle health monitoring in older ad…
View article: Kinetics of EBV antibody‐based NPC risk scores in Taiwan NPC multiplex families
Kinetics of EBV antibody‐based NPC risk scores in Taiwan NPC multiplex families Open
Nasopharyngeal carcinoma (NPC) risk prediction models based on Epstein–Barr virus (EBV)‐antibody testing have shown potential for screening of NPC; however, the long‐term stability is unclear. Here, we investigated the kinetics of two EBV‐…
View article: Malnutrition and Muscle Loss Mediate the Association between NT-proBNP and Mortality in Hospitalized Older Adults
Malnutrition and Muscle Loss Mediate the Association between NT-proBNP and Mortality in Hospitalized Older Adults Open
Background & Aims The purpose of this study was to assess the association between N-terminal prohormone of type B natriuretic peptide (NT-proBNP) and long-term mortality in hospitalized oldest-old adults and to explore the mediating role o…
View article: Estimated pulse wave velocity added additional prognostic information in general population: Evidence from National Health and Nutrition Examination Survey (NHANES) 1999–2018
Estimated pulse wave velocity added additional prognostic information in general population: Evidence from National Health and Nutrition Examination Survey (NHANES) 1999–2018 Open
In general population, the present study demonstrated the association between ePWV and all-cause, cardiovascular mortality is independent of cardiovascular risk factors and traditional risk estimated model. ePWV also added additional infor…
View article: NAD+ exhaustion by CD38 upregulation contributes to blood pressure elevation and vascular damage in hypertension
NAD+ exhaustion by CD38 upregulation contributes to blood pressure elevation and vascular damage in hypertension Open
Hypertension is characterized by endothelial dysfunction and arterial stiffness, which contribute to the pathogenesis of atherosclerotic cardiovascular diseases. Nicotinamide adenine dinucleotide (NAD + ) is an indispensable cofactor in al…
View article: TBC1D15 deficiency protects against doxorubicin cardiotoxicity via inhibiting DNA-PKcs cytosolic retention and DNA damage
TBC1D15 deficiency protects against doxorubicin cardiotoxicity via inhibiting DNA-PKcs cytosolic retention and DNA damage Open
Clinical application of doxorubicin (DOX) is heavily hindered by DOX cardiotoxicity. Several theories were postulated for DOX cardiotoxicity including DNA damage and DNA damage response (DDR), although the mechanism(s) involved remains to …
View article: Serum creatinine/cystatin C ratio is a predictor of all-cause mortality for older adults over 80 years
Serum creatinine/cystatin C ratio is a predictor of all-cause mortality for older adults over 80 years Open
View article: Lower serum FT3 within the reference range is associated with mortality for older adults over 80 years of age with sarcopenia
Lower serum FT3 within the reference range is associated with mortality for older adults over 80 years of age with sarcopenia Open
View article: Berberine Improves Vascular Dysfunction by Inhibiting Trimethylamine-N-oxide via Regulating the Gut Microbiota in Angiotensin II-Induced Hypertensive Mice
Berberine Improves Vascular Dysfunction by Inhibiting Trimethylamine-N-oxide via Regulating the Gut Microbiota in Angiotensin II-Induced Hypertensive Mice Open
Berberine (BBR) has been demonstrated to exert cardiovascular protective effects by regulating gut microbiota. However, few studies examine the effect of BBR on the gut microbiota in hypertension. This study aims to investigate the role of…
View article: Sarcopenia Index Based on Serum Creatinine and Cystatin C is Associated with Mortality, Nutritional Risk/Malnutrition and Sarcopenia in Older Patients
Sarcopenia Index Based on Serum Creatinine and Cystatin C is Associated with Mortality, Nutritional Risk/Malnutrition and Sarcopenia in Older Patients Open
Chenxi Ren,1,2,* Hang Su,1,* Jun Tao,1 Ying Xie,2 Xiaoyan Zhang,1 Qihao Guo1 1Department of gerontology, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai, 200233, People’s Republic of China; 2Department of Endocrin…
View article: TMAO-Activated Hepatocyte-Derived Exosomes Impair Angiogenesis via Repressing CXCR4
TMAO-Activated Hepatocyte-Derived Exosomes Impair Angiogenesis via Repressing CXCR4 Open
Objective: Trimethylamine-N-oxide (TMAO) was found to play crucial roles in vascular endothelial function. However, the exact molecular mechanisms are not yet entirely clear. Recently, we found that exosomes (Exos) isolated from TMAO-treat…
View article: The challenges and optimization of cell-based therapy for cardiovascular disease
The challenges and optimization of cell-based therapy for cardiovascular disease Open
With the hope of achieving real cardiovascular repair, cell-based therapy raised as a promising strategy for the treatment of cardiovascular disease (CVD) in the past two decades. Various types of cells have been studied for their reparati…
View article: Egg consumption improves vascular and gut microbiota function without increasing inflammatory, metabolic, and oxidative stress markers
Egg consumption improves vascular and gut microbiota function without increasing inflammatory, metabolic, and oxidative stress markers Open
Egg consumption is one of the many inconsistencies in evidence linking dietary cholesterol to cardiovascular disease (CVD). In addition, the gut microbiota and its metabolite, trimethylamine‐N‐oxide (TMAO), have been shown to play a crucia…
View article: Non-invasive Systemic Hemodynamic Index in Vascular Risk Stratification Tailored for Hypertensives
Non-invasive Systemic Hemodynamic Index in Vascular Risk Stratification Tailored for Hypertensives Open
Vascular dysfunction is a key hallmark of hypertension and related cardiovascular outcomes. As a well-known hemodynamic disease, hypertension is characterized by abnormal ventricular-vascular interactions. Complementing non-invasive system…
View article: Red blood cell distribution width and left ventricular mass index predict poor outcomes in patients with hypertrophic cardiomyopathy
Red blood cell distribution width and left ventricular mass index predict poor outcomes in patients with hypertrophic cardiomyopathy Open
Aim: To evaluate the prognostic utility of red blood cell distribution width (RDW) and left ventricular mass index (LVMI) in patients with hypertrophic cardiomyopathy (HCM). Patients & methods: This study is a retrospective cohort analysis…
View article: Progress of clinical evaluation for vascular aging in humans
Progress of clinical evaluation for vascular aging in humans Open
Human society is experiencing a serious aging process. Age-related arteriosclerotic cardiovascular diseases (ASCVD) are the most common cause of deaths around the world and bring a huge burden on the whole society. Vascular aging-related p…
View article: Multi-dimensional Integrated Detection of Electromagnetic Acoustic SV Wave and Surface Wave for Steel Rail
Multi-dimensional Integrated Detection of Electromagnetic Acoustic SV Wave and Surface Wave for Steel Rail Open
：The total operating mileage of China's railways is nearly 140 000 km, and a large number of rails have been in service for a long time, which may cause many potential safety hazards.As a non-contact and high penetration detection technolo…
View article: Design and Characteristics of Electromagnetic Acoustic Transducers with Controllable Magnetic Force
Design and Characteristics of Electromagnetic Acoustic Transducers with Controllable Magnetic Force Open
View article: Xinkeshu Improves Endothelial Function and Augments Reendothelialization Capacity in Coronary Artery Disease with Anxiety/Depression
Xinkeshu Improves Endothelial Function and Augments Reendothelialization Capacity in Coronary Artery Disease with Anxiety/Depression Open
The disruption of endothelial homeostasis is the hallmark of coronary artery disease (CAD) and psychological disorders such as anxiety/depression. Xinkeshu (XKS), a traditional Chinese patent medicine, plays an essential role in CAD and ps…
View article: Neck-to-height ratio and arterial stiffness in Chinese adults: cross-sectional associations in a community-based cohort
Neck-to-height ratio and arterial stiffness in Chinese adults: cross-sectional associations in a community-based cohort Open
Objectives: The aim of this study was to investigate the association between neck-to-height ratio (NHR) and arterial stiffness in adults from a community-based Chinese cohort in a cross-sectional study. Methods: We conducted cross-sectiona…
View article: All disease stems from vessels
All disease stems from vessels Open
Although rapid advances in vascular biology and therapeutics in the last several decades have brought revolutionary improvement to morbidity and mortality of cardiovascular disease (CVD), vascular dysfunction still plays a central role in …
View article: Circulating senescent angiogenic T cells are linked with endothelial dysfunction and systemic inflammation in hypertension
Circulating senescent angiogenic T cells are linked with endothelial dysfunction and systemic inflammation in hypertension Open
Objective: Angiogenic T cells (T ang cells), a recently discovered T-cell subset, have been reported involved in the repair of endothelial injury. The purpose of this study was to explore the correlation of immunologic senescence and pro-i…
View article: Bimodal Imaging‐Visible Nanomedicine Integrating CXCR4 and VEGFa Genes Directs Synergistic Reendothelialization of Endothelial Progenitor Cells
Bimodal Imaging‐Visible Nanomedicine Integrating CXCR4 and VEGFa Genes Directs Synergistic Reendothelialization of Endothelial Progenitor Cells Open
A major challenge to treat vascular endothelial injury is the restoration of endothelium integrity in which endothelial progenitor cells (EPCs) plays a central role. Transplantation of EPCs as a promising therapeutic means is subject to tw…
View article: A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks
A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks Open