Junki Kwon
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View article: Correction: Kim et al. Neuroprotective Effect of Statins in a Rat Model of Chronic Ocular Hypertension. Int. J. Mol. Sci. 2021, 22, 12500
Correction: Kim et al. Neuroprotective Effect of Statins in a Rat Model of Chronic Ocular Hypertension. Int. J. Mol. Sci. 2021, 22, 12500 Open
In the original publication [...]
View article: Neuroprotective Effect of Statins in a Rat Model of Chronic Ocular Hypertension
Neuroprotective Effect of Statins in a Rat Model of Chronic Ocular Hypertension Open
Glaucoma is an optic neuropathy in which the degeneration of retinal ganglion cells (RGCs) results in irreversible vison loss. Therefore, neuroprotection of RGCs from glaucomatous afflictions is crucial for glaucoma treatment. In this stud…
View article: Statins Suppress TGF-β2-Mediated MMP-2 and MMP-9 Expression and Activation Through RhoA/ROCK Inhibition in Astrocytes of the Human Optic Nerve Head
Statins Suppress TGF-β2-Mediated MMP-2 and MMP-9 Expression and Activation Through RhoA/ROCK Inhibition in Astrocytes of the Human Optic Nerve Head Open
Statins inhibited the TGF-β2-mediated regulation of MMP-2 and MMP-9 by inhibiting the RhoA/ROCK signaling pathway. Considering the role of MMP in ECM remodeling, the present findings support the notion that statins positively impact ECM re…
View article: Vitreous Zonule and its Relation to Anterior Chamber Angle Characteristics in Primary Angle Closure
Vitreous Zonule and its Relation to Anterior Chamber Angle Characteristics in Primary Angle Closure Open
Precis: Primary angle-closure (PAC) eyes with no vitreous zonule (VZ) appear to have a narrower angle despite similar lens vault and iris configuration than eyes with visible VZ. Purpose: To assess the clinical significance of the VZ in PA…
View article: Greater Severity of Glaucomatous Damage in Eyes With Than Without Choroidal Microvasculature Dropout in Open-Angle Glaucoma
Greater Severity of Glaucomatous Damage in Eyes With Than Without Choroidal Microvasculature Dropout in Open-Angle Glaucoma Open
OAG eyes with CMvD showed significantly lower cpRNFLT and mGCIPLT than those without CMvD at the hemiretinae corresponding to intact hemifields, thus requiring more vigilant attention for greater disease severity.
View article: Pseudophakic Pupillary Block after Toxic Anterior Segment Syndrome
Pseudophakic Pupillary Block after Toxic Anterior Segment Syndrome Open
Purpose: We report a case of pseudophakic pupillary block after toxic anterior segment syndrome (TASS).Case summary: An 84-year-old woman underwent phacoemulsification and intraocular lens implantation in the posterior chamber.Six days aft…
View article: Additive Role of Optical Coherence Tomography Angiography Vessel Density Measurements in Glaucoma Diagnoses
Additive Role of Optical Coherence Tomography Angiography Vessel Density Measurements in Glaucoma Diagnoses Open
When OCTA was combined with OCT, the specificity of glaucoma diagnoses were enhanced. OCTA may compensate for the shortcomings of OCT in the diagnosis of glaucoma.
View article: An Optical Coherence Tomography Angiography Study of the Relationship Between Foveal Avascular Zone Size and Retinal Vessel Density
An Optical Coherence Tomography Angiography Study of the Relationship Between Foveal Avascular Zone Size and Retinal Vessel Density Open
OCTA-derived FAZ area and perimeter showed statistically significant correlations with VDs measured at various retinal locations with spatial correspondence in OAG.
View article: Effects of Choroidal Thickness on Refractive Outcome Following Cataract Surgery in Primary Angle Closure
Effects of Choroidal Thickness on Refractive Outcome Following Cataract Surgery in Primary Angle Closure Open
Our results indicate that preoperative subfoveal CT and the difference between pre- and postoperative subfoveal CT are significant factors for predicting refractive error after cataract surgery in PAC patients. These findings should be con…
View article: Factors Associated with Outcomes of Combined Phacoemulsification and Ahmed Glaucoma Valve Implantation
Factors Associated with Outcomes of Combined Phacoemulsification and Ahmed Glaucoma Valve Implantation Open
Combined phacoemulsification and AGV implantation is an effective and safe surgical option for patients with refractory glaucoma and cataract. Postoperative tube-iris touch is an indicator of poor prognosis.
View article: Quantitative optical coherence tomography angiography of macular vascular structure and foveal avascular zone in glaucoma
Quantitative optical coherence tomography angiography of macular vascular structure and foveal avascular zone in glaucoma Open
Decreased macular VD, increased FAZ perimeter, and decreased FAZ circularity index were observed in eyes with glaucoma using OCT-A. With refractive error adjusted, these parameters showed considerable diagnostic value for glaucoma. FAZ cir…
View article: Alterations of the Foveal Avascular Zone Measured by Optical Coherence Tomography Angiography in Glaucoma Patients With Central Visual Field Defects
Alterations of the Foveal Avascular Zone Measured by Optical Coherence Tomography Angiography in Glaucoma Patients With Central Visual Field Defects Open
Microcirculatory alterations in the perifovea are spatially correlated with central VF loss. Loss of FAZ circularity was significantly associated with presence of CVFD, whereas FAZ area was significantly associated with severity of CVFD.
View article: Effect of Preoperative Intravitreal Bevacizumab on the Surgical Outcome of Neovascular Glaucoma at Different Stages
Effect of Preoperative Intravitreal Bevacizumab on the Surgical Outcome of Neovascular Glaucoma at Different Stages Open
Purpose . To evaluate the effect of preoperative intravitreal bevacizumab (IVB) injection on the surgical outcome of Ahmed glaucoma valve (AGV) implantation according to the angle status in neovascular glaucoma (NVG) eyes. Materials and Me…
View article: Circadian Patterns of Intraocular Pressure Fluctuation among Normal-Tension Glaucoma Optic Disc Phenotypes
Circadian Patterns of Intraocular Pressure Fluctuation among Normal-Tension Glaucoma Optic Disc Phenotypes Open
Based on 24-h habitual-position IOP data, FI is associated with significant nocturnal IOP elevation, while no such nocturnal IOP elevation is observed in MG ODP. In untreated NTG, there are also significant differences in the 24-h IOP patt…
View article: Comparison of Cytotoxic Effects on Rabbit Corneal Endothelium between Preservative-free and Preservative-containing Dorzolamide/timolol
Comparison of Cytotoxic Effects on Rabbit Corneal Endothelium between Preservative-free and Preservative-containing Dorzolamide/timolol Open
The main cause of corneal endothelial toxicity was due to the preservative in the dorzolamide/timolol fixed combination eyedrops, and not the active ingredient. Thus, it appears to be safer to use preservative-free eyedrops during the earl…