Jun‐Li Cao
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View article: Dysfunction of the rostral lateral septum GABAergic neurons induces mania-like behavior in male mice
Dysfunction of the rostral lateral septum GABAergic neurons induces mania-like behavior in male mice Open
View article: RNF168 dephosphorylation ameliorates cognitive decline in Aβ-based mouse models of Alzheimer’s disease
RNF168 dephosphorylation ameliorates cognitive decline in Aβ-based mouse models of Alzheimer’s disease Open
View article: Long-term Outcomes of Additional Surgical Versus Non-surgical Treatment After Non-curative Endoscopic Resection for T1 Superficial Esophageal Cancer
Long-term Outcomes of Additional Surgical Versus Non-surgical Treatment After Non-curative Endoscopic Resection for T1 Superficial Esophageal Cancer Open
Background: Endoscopic resection (ER) is the main treatment for T1 superficial oesophageal cancer (SEC). Additional surgical resection (ASR) is recommended to improve the prognosis of patients with non-curative resection who are at high ri…
View article: Transcutaneous Auricular Vagus Nerve Stimulation for Postpartum Contraction Pain During Elective Cesarean Delivery
Transcutaneous Auricular Vagus Nerve Stimulation for Postpartum Contraction Pain During Elective Cesarean Delivery Open
Importance Postpartum uterine contraction pain manifests as a severe, intermittent lower abdominal discomfort caused by uterine contraction during the early puerperium. Transcutaneous auricular vagus nerve stimulation (taVNS) has demonstra…
View article: Effect of transcutaneous auricular vagus nerve stimulation on postoperative liver function in patients undergoing partial hepatectomy: a study protocol for a prospective, double-blind, randomized controlled trial
Effect of transcutaneous auricular vagus nerve stimulation on postoperative liver function in patients undergoing partial hepatectomy: a study protocol for a prospective, double-blind, randomized controlled trial Open
Background Partial hepatectomy remains a primary therapeutic intervention for various hepatic diseases. However, several intraoperative factors, including surgical manipulation, substantial blood loss, the need for blood transfusions, and …
View article: SERBP1-PCIF1 complex-controlled m6Am modification in glutamatergic neurons of the primary somatosensory cortex is required for neuropathic pain in mice
SERBP1-PCIF1 complex-controlled m6Am modification in glutamatergic neurons of the primary somatosensory cortex is required for neuropathic pain in mice Open
View article: CaBBX9, an interaction partner of autophagy-related protein CaATG8c, negatively regulates the heat tolerance of pepper
CaBBX9, an interaction partner of autophagy-related protein CaATG8c, negatively regulates the heat tolerance of pepper Open
To explore the molecular mechanisms by which autophagy contributes to pepper’s heat tolerance, we previously identified the zinc-finger protein B-BOX 9/CONSTANS-LIKE 13 (CaBBX9/CaCOL13) as an interaction partner of the autophagy related pr…
View article: Distinct nucleus accumbens neural pathways underlie separate behavioral features of chronic pain and comorbid depression
Distinct nucleus accumbens neural pathways underlie separate behavioral features of chronic pain and comorbid depression Open
The comorbidity of depressive symptoms in chronic pain has been recognized as a key health issue. However, whether discrete circuits underlie behavioral subsets of chronic pain and comorbid depression has not been addressed. Here, we repor…
View article: Risk Factors and Prediction of Chronic Postsurgical Pain Among Patients with Distal Lower fracture: Cohort Analysis
Risk Factors and Prediction of Chronic Postsurgical Pain Among Patients with Distal Lower fracture: Cohort Analysis Open
Background: The surgical interventions aimed at fracture repair can paradoxically lead to chronic postoperative pain (CPSP), which is associated with depression, impaired quality of life, and increased societal burden. This phenomenon is p…
View article: In situ structure and assembly of the ABC-type tripartite pump MacAB-TolC
In situ structure and assembly of the ABC-type tripartite pump MacAB-TolC Open
The MacAB-TolC tripartite efflux pump is widely distributed in Gram-negative bacteria, extruding antibiotics and virulence factors that lead to multidrug resistance and pathogenicity. However, the in situ structure and assembly mechanism o…
View article: Peptide-based electrochemical sensor for sensitive detection of amyloid-β oligomer with laccase-mimicking nanozyme assemblies as a signal amplifier
Peptide-based electrochemical sensor for sensitive detection of amyloid-β oligomer with laccase-mimicking nanozyme assemblies as a signal amplifier Open
View article: Excitatory projections from the nucleus reuniens to the medial prefrontal cortex modulate pain and depression-like behaviors in mice
Excitatory projections from the nucleus reuniens to the medial prefrontal cortex modulate pain and depression-like behaviors in mice Open
The medial prefrontal cortex (mPFC) is implicated in emotional processing, cognition, and pain sensation, moreover, its circuitry undergoes neuroplastic changes in chronic pain. Although the nucleus reuniens (RE) of the thalamus provides s…
View article: Stellate ganglion block diminishes consolidation of conditioned fear memory in mice by inhibiting the locus coeruleus to the basolateral amygdala neural circuit
Stellate ganglion block diminishes consolidation of conditioned fear memory in mice by inhibiting the locus coeruleus to the basolateral amygdala neural circuit Open
View article: A ventral pallidum-locus coeruleus-lateral hypothalamus pathway modulates brain arousal in freely behaving and isoflurane-anesthetized male mice
A ventral pallidum-locus coeruleus-lateral hypothalamus pathway modulates brain arousal in freely behaving and isoflurane-anesthetized male mice Open
View article: PD-1 suppression enhances HIV reactivation and T-cell immunity via MAPK/NF-κB signaling
PD-1 suppression enhances HIV reactivation and T-cell immunity via MAPK/NF-κB signaling Open
View article: Correction: Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area
Correction: Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area Open
View article: NAT10 inhibition alleviates astrocyte autophagy by impeding ac4C acetylation of Timp1 mRNA in ischemic stroke
NAT10 inhibition alleviates astrocyte autophagy by impeding ac4C acetylation of Timp1 mRNA in ischemic stroke Open
View article: Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area
Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area Open
View article: Genome-wide identification of the peach LOB/LBD genes and the positive role of the PpNAP4-PpLOB1 module in peach fruit softening
Genome-wide identification of the peach LOB/LBD genes and the positive role of the PpNAP4-PpLOB1 module in peach fruit softening Open
View article: Selective activation of SIGMAR1 in anterior cingulate cortex glutamatergic neurons facilitates comorbid pain in depression in male mice
Selective activation of SIGMAR1 in anterior cingulate cortex glutamatergic neurons facilitates comorbid pain in depression in male mice Open
View article: Lysosomes finely control macrophage inflammatory function via regulating the release of lysosomal Fe2+ through TRPML1 channel
Lysosomes finely control macrophage inflammatory function via regulating the release of lysosomal Fe2+ through TRPML1 channel Open
Lysosomes are best known for their roles in inflammatory responses by engaging in autophagy to remove inflammasomes. Here, we describe an unrecognized role for the lysosome, showing that it finely controls macrophage inflammatory function …
View article: Development of competency framework for postgraduate anesthesia training in China: a Delphi study
Development of competency framework for postgraduate anesthesia training in China: a Delphi study Open
View article: Peptide-Based Electrochemical Sensor for Sensitive Detection of Amyloid-Β Oligomer with Laccase-Mimicking Nanoaggregates as a Signal Amplifier
Peptide-Based Electrochemical Sensor for Sensitive Detection of Amyloid-Β Oligomer with Laccase-Mimicking Nanoaggregates as a Signal Amplifier Open
View article: Hierarchical architecture of neo-sex chromosomes and accelerated adaptive evolution in tortricid moths
Hierarchical architecture of neo-sex chromosomes and accelerated adaptive evolution in tortricid moths Open
Sex chromosomes can expand through fusion with autosomes, thereby acquiring unique evolutionary patterns. In butterflies and moths (Lepidoptera), these sex chromosome–autosome (SA) fusions occur relatively frequently, suggesting possible e…
View article: Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment
Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment Open
Memory impairment in chronic pain patients is substantial and common, and few therapeutic strategies are available. Chronic pain-related memory impairment has susceptible and unsusceptible features. Therefore, exploring the underlying mech…
View article: Author response: Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment
Author response: Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment Open
View article: Effect of continuous infusion in alleviating pain during male urethral catheterization
Effect of continuous infusion in alleviating pain during male urethral catheterization Open
The study protocol was registered in the Chinese Clinical Trial Registry (ChiCTR2300070866) ( https://www.chictr.org.cn/showproj.html?proj=194591 ) on Apr. 25th, 2023.
View article: Wonderland: Navigating 3D Scenes from a Single Image
Wonderland: Navigating 3D Scenes from a Single Image Open
How can one efficiently generate high-quality, wide-scope 3D scenes from arbitrary single images? Existing methods suffer several drawbacks, such as requiring multi-view data, time-consuming per-scene optimization, distorted geometry in oc…
View article: SnapGen: Taming High-Resolution Text-to-Image Models for Mobile Devices with Efficient Architectures and Training
SnapGen: Taming High-Resolution Text-to-Image Models for Mobile Devices with Efficient Architectures and Training Open
Existing text-to-image (T2I) diffusion models face several limitations, including large model sizes, slow runtime, and low-quality generation on mobile devices. This paper aims to address all of these challenges by developing an extremely …
View article: Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment
Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment Open
Memory impairment in chronic pain patients is substantial and common, and few therapeutic strategies are available. Chronic pain-related memory impairment has susceptible and unsusceptible features. Therefore, exploring the underlying mech…