Junling Ma
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View article: Distributions of prevalence and daily new cases in a stochastic linear SEIR model
Distributions of prevalence and daily new cases in a stochastic linear SEIR model Open
Model parameters are typically estimated by calibrating the model to new case counts. This is important for understanding disease dynamics and guiding control measures. For parameter estimation, it is essential to identify the distribution…
View article: Original Antigenic Sin in <scp>CD4</scp>+ T Cells
Original Antigenic Sin in <span>CD4</span>+ T Cells Open
Original antigenic sin (OAS) describes the phenomenon in which prior exposure to an antigen weakens the adaptive antibody response to a subsequent heterologous infection. This phenomenon can diminish the effectiveness of immunity acquired …
View article: Association between multimorbidity and having less than 20 natural teeth among Chinese older adults: a cross-sectional study
Association between multimorbidity and having less than 20 natural teeth among Chinese older adults: a cross-sectional study Open
Understanding the impact of multimorbidity on having less than 20 natural teeth is crucial for safeguarding the oral health of older adults with multimorbidity. This study aimed to analyze the association between multimorbidity and having …
View article: Novel Polarization Construction Method and Synchronization Algorithm for Underwater Acoustic Channel Under T-Distribution Noise Environment
Novel Polarization Construction Method and Synchronization Algorithm for Underwater Acoustic Channel Under T-Distribution Noise Environment Open
Underwater acoustic channel (UWAC) is characterized by significant multipath effects, strong time-varying properties and complex noise environments, which make achieving high-rate and reliable underwater communication a formidable task. To…
View article: Deregulated methylation and expression of PCDHGB7 in patients with non-small cell lung cancer: a novel prognostic and immunological biomarker
Deregulated methylation and expression of PCDHGB7 in patients with non-small cell lung cancer: a novel prognostic and immunological biomarker Open
Backgrounds Protocadherin gamma subfamily B, 7 (PCDHGB7), a member of the protocadherin family, plays critical roles in neuronal connections and has been implicated in female reproductive system cancers. Its function in lung cancer has not…
View article: The dynamics of CD4+ T cell proliferation and regulation
The dynamics of CD4+ T cell proliferation and regulation Open
We use mathematical modeling to study the proliferation dynamics of CD4+ T cells within an immune response. This proliferation is driven by the autocrine reaction of helper T cells and interleukin-2 (IL-2), and regulated by natural regulat…
View article: The optimal spatially-dependent control measures to effectively and economically eliminate emerging infectious diseases
The optimal spatially-dependent control measures to effectively and economically eliminate emerging infectious diseases Open
Non-pharmaceutical interventions (NPIs) are effective in mitigating infections during the early stages of an infectious disease outbreak. However, these measures incur significant economic and livelihood costs. To address this, we develope…
View article: <i>Helicobacter pylori</i> Treatment and Gastric Cancer Risk Among Individuals With High Genetic Risk for Gastric Cancer
<i>Helicobacter pylori</i> Treatment and Gastric Cancer Risk Among Individuals With High Genetic Risk for Gastric Cancer Open
Importance Helicobacter pylori treatment and nutrition supplementation may protect against gastric cancer (GC), but whether the beneficial effects only apply to potential genetic subgroups and whether high genetic risk may be counteracted …
View article: The role of long-lived plasma cells in viral clearance
The role of long-lived plasma cells in viral clearance Open
The adaptive immune system has two types of plasma cells (PC), long-lived plasma cells (LLPC) and short-lived plasma cells (SLPC), that differ in their lifespan. In this paper, we propose that LLPC is crucial to the clearance of viral part…
View article: Novel High-Precision and High-Robustness Localization Algorithm for Underwater-Environment-Monitoring Wireless Sensor Networks
Novel High-Precision and High-Robustness Localization Algorithm for Underwater-Environment-Monitoring Wireless Sensor Networks Open
In marine ecological environment monitoring, the acquisition of node location information is crucial, and the absence of location information can render the collected data meaningless. Compared to the rest of the distance-based localizatio…
View article: Metabolite Alterations and Interactions with Microbiota in Helicobacter pylori-Associated Gastric Lesions
Metabolite Alterations and Interactions with Microbiota in Helicobacter pylori-Associated Gastric Lesions Open
In this study, a panel was established including differential metabolites, genera, and their interactions, which may help to discriminate high-risk subjects for progression from mild lesions to advanced precancerous lesions in short-term a…
View article: The effectiveness of control measures during the 2022 COVID-19 outbreak in Shanghai, China
The effectiveness of control measures during the 2022 COVID-19 outbreak in Shanghai, China Open
Background In March 2022, the Omicron variant of SARS-CoV-2 spread rapidly in Shanghai, China. The city adopted strict non-pharmacological intervention (NPI) measures, including lockdown (implemented on March 28 in Pudong and April 1 in Pu…
View article: Data from Methylation and Expression of Nonclustered Protocadherins Encoding Genes and Risk of Precancerous Gastric Lesions in a High-Risk Population
Data from Methylation and Expression of Nonclustered Protocadherins Encoding Genes and Risk of Precancerous Gastric Lesions in a High-Risk Population Open
Nonclustered protocadherins (PCDH) family is a group of cell–cell adhesion molecules. We have found differentially methylated genes in the nonclustered PCDHs family associated with Helicobacter pylori (H. pylori) infection in prior genome-…
View article: Data from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
Data from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population Open
Background: Manganese superoxide dismutase is the primary antioxidant enzyme in the mitochondria and is involved in carcinogenesis. To investigate the association between MnSOD Val16Ala polymorphism and risk of advanced gastric lesions, an…
View article: Supplementary Table 3 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
Supplementary Table 3 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population Open
Supplementary Table 3 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
View article: Supplementary Table 1 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
Supplementary Table 1 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population Open
Supplementary Table 1 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
View article: Supplementary Table 2 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
Supplementary Table 2 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population Open
Supplementary Table 2 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
View article: Data from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
Data from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population Open
Background: Manganese superoxide dismutase is the primary antioxidant enzyme in the mitochondria and is involved in carcinogenesis. To investigate the association between MnSOD Val16Ala polymorphism and risk of advanced gastric lesions, an…
View article: Supplementary Table 2 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
Supplementary Table 2 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population Open
Supplementary Table 2 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
View article: Supplementary Table 3 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
Supplementary Table 3 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population Open
Supplementary Table 3 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
View article: Supplementary Table 1 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
Supplementary Table 1 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population Open
Supplementary Table 1 from Manganese Superoxide Dismutase Polymorphism and Risk of Gastric Lesions, and Its Effects on Chemoprevention in a Chinese Population
View article: The effects of disease control measures on the reproduction number of COVID-19 in British Columbia, Canada
The effects of disease control measures on the reproduction number of COVID-19 in British Columbia, Canada Open
We propose a new method to estimate the change of the effective reproduction number with time, due to either disease control measures or seasonally varying transmission rate. We validate our method using a simulated epidemic curve and show…
View article: A contact tracing SIR model for randomly mixed populations
A contact tracing SIR model for randomly mixed populations Open
Contact tracing is an important intervention measure to control infectious diseases. We present a new approach that borrows the edge dynamics idea from network models to track contacts included in a compartmental SIR model for an epidemic …
View article: ESTIMATING THE MOSQUITO DENSITY IN GUANGZHOU CITY, CHINA
ESTIMATING THE MOSQUITO DENSITY IN GUANGZHOU CITY, CHINA Open
Mosquito is a vector of many diseases. Predicting the trend of mosquito density is important for early warning and control of mosquito diseases. In this paper, we fit a discrete time mosquito model developed by Gong et al. in 2011, which c…
View article: Temperature dependent developmental time for the larva stage of Aedes aegypti
Temperature dependent developmental time for the larva stage of Aedes aegypti Open
We first verify that the time from the emergence of larva to the emergence of pupa (i.e., the duration of the larva stage) for Aedes aegypti is approximately gamma distributed, provided that the pupation process is successful. This is illu…
View article: Beneficial effects of endoscopic screening on gastric cancer and optimal screening interval: a population-based study
Beneficial effects of endoscopic screening on gastric cancer and optimal screening interval: a population-based study Open
Background The effectiveness of endoscopic screening on gastric cancer has not been widely investigated in China and the screening interval of repeated screening has not been determined. Methods In a population-based prospective study, we …
View article: Estimating the Mosquito Density in Guangzhou City, China
Estimating the Mosquito Density in Guangzhou City, China Open
Mosquito is a vector of many diseases. Predicting the trend of mosquito density is important for early warning and control of mosquito diseases. In this paper, we fit a discrete time mosquito model developed by Gong et al. in 2011, which c…