Jun Liu
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View article: Biomimetic nanovesicle vaccines derived from dendritic cells sensitized with whole tumor antigens for melanoma immunotherapy
Biomimetic nanovesicle vaccines derived from dendritic cells sensitized with whole tumor antigens for melanoma immunotherapy Open
View article: Comparative outcomes of treatment with versus without definitive thoracic radiotherapy in locally advanced inoperable non-small cell lung cancer during the immunotherapy era: a Chinese real-world study
Comparative outcomes of treatment with versus without definitive thoracic radiotherapy in locally advanced inoperable non-small cell lung cancer during the immunotherapy era: a Chinese real-world study Open
This study confirms that thoracic RT remains essential for inoperable LA-NSCLC in the immunotherapy era. An exploratory analysis suggests that a potential strategy could involve ≤4 cycles of CIT induction followed by concurrent CRT (cCRT) …
View article: Proteomics profiling for the global and acetylated proteins of High-Grade Serous Ovarian Carcinoma
Proteomics profiling for the global and acetylated proteins of High-Grade Serous Ovarian Carcinoma Open
Background High-grade serous ovarian cancer (HGSOC) is the main type of ovarian cancer with a poor prognosis. Although protein omics is widely used in HGSOC, the general situation of acetylated proteins in HGSOC is still uncertain, which i…
View article: Identification and predictive machine learning model construction of gut microbiota associated with carcinoembryonic antigens in colorectal cancer
Identification and predictive machine learning model construction of gut microbiota associated with carcinoembryonic antigens in colorectal cancer Open
Carcinoembryonic antigen (CEA) is a critical colorectal cancer (CRC) biomarker, but its mechanistic link to gut microbiota remains unclear. This study characterized gut microbiota differences between high-CEA (H-CEA) and low-CEA (L-CEA) CR…
View article: Dark green urine following endoscopic ultrasound-guided hepaticogastrostomy: A case report
Dark green urine following endoscopic ultrasound-guided hepaticogastrostomy: A case report Open
BACKGROUND Endoscopic ultrasound-guided biliary drainage, including endoscopic ultrasound-guided choledochoduodenostomy and endoscopic ultrasound-guided hepatogastrostomy (EUS-HGS), is an efficacious alternative to endoscopic retrograde ch…
View article: Videos in short-video sharing platforms as sources of information on osteoarthritis: cross-sectional content analysis study
Videos in short-video sharing platforms as sources of information on osteoarthritis: cross-sectional content analysis study Open
Background Osteoarthritis (OA) is a debilitating condition characterized by pain, stiffness, and impaired mobility, significantly affecting patients' quality of life. Health education is crucial in helping individuals understand OA and its…
View article: ctDNA detects residual disease after neoadjuvant chemoradiotherapy and guides adjuvant therapy in esophageal squamous cell carcinoma
ctDNA detects residual disease after neoadjuvant chemoradiotherapy and guides adjuvant therapy in esophageal squamous cell carcinoma Open
View article: Percutaneous endocardial septal radiofrequency ablation in patients with hypertrophic obstructive cardiomyopathy
Percutaneous endocardial septal radiofrequency ablation in patients with hypertrophic obstructive cardiomyopathy Open
View article: Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer
Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer Open
This study focuses on the significant role between gut microbiota and lymph node metastasis (LNM) in colorectal cancer (CRC). By conducting 16S rRNA sequencing on fecal samples from 147 CRC patients and combining it with the linear discrim…
View article: A novel mesothelioma molecular classification based on malignant cell differentiation
A novel mesothelioma molecular classification based on malignant cell differentiation Open
The novel molecular classification system and the prognostic prediction model might benefit the management of MESO patients.
View article: Comparison of clinicopathological characteristics and survival outcomes between solitary and multiple rectal neuroendocrine tumors: a propensity score-matched study
Comparison of clinicopathological characteristics and survival outcomes between solitary and multiple rectal neuroendocrine tumors: a propensity score-matched study Open
Introduction Multiple rectal neuroendocrine tumors (RNETs) are rare rectal malignancies, and there is no consensus on their characteristics and treatments. This study aimed to explore the heterogeneity of key morphological parameters in mu…
View article: Physiological pattern differences in non-intubated vs. intubated thoracic anesthesia based on time series analysis
Physiological pattern differences in non-intubated vs. intubated thoracic anesthesia based on time series analysis Open
Using a real-time database, the non-intubated thoracic anesthesia management pattern is firstly clearly demonstrated, which differs from the intubated anesthesia with the machine-controlled pattern. Reducing intravenous anesthetics with re…
View article: A systematic review and meta-analysis of Anterior Cervical Decompression and Fusion: Comparing the ROI-CTM Self-Locking System with Traditional Cage-Plate Internal Fixation in the Treatment of Degenerative Cervical Spondylosis
A systematic review and meta-analysis of Anterior Cervical Decompression and Fusion: Comparing the ROI-CTM Self-Locking System with Traditional Cage-Plate Internal Fixation in the Treatment of Degenerative Cervical Spondylosis Open
Objective: Anterior Cervical Decompression and Fusion (ACDF) is a well-established surgical intervention for degenerative cervical spondylosis. While the use of plates is known to improve fusion rates and stability, it may also be associat…
View article: Clinical value of contrast-enhanced ultrasound and contrast-enhanced CT in the diagnosis of HBV-infected hepatocellular carcinoma
Clinical value of contrast-enhanced ultrasound and contrast-enhanced CT in the diagnosis of HBV-infected hepatocellular carcinoma Open
View article: Elevated platelet distribution width and diabetes may serve as preoperative predictors of microvascular invasion in primary hepatocellular carcinoma
Elevated platelet distribution width and diabetes may serve as preoperative predictors of microvascular invasion in primary hepatocellular carcinoma Open
This study confirmed PDW and diabetes mellitus as reliable indicators for predicting preoperative MVI in HCC and established a corresponding predictive model. Future research should further explore the underlying mechanisms and enhance cli…
View article: Application of the CHINESE Recovery Model in Community Integration of Individuals with Mental Disorders: A Practice-Based Study
Application of the CHINESE Recovery Model in Community Integration of Individuals with Mental Disorders: A Practice-Based Study Open
Amidst rapid social transformation and accelerated living rhythms in contemporary China, mental health disorders have evolved into a pressing societal concern. Traditional treatment approaches emphasizing institutional care and pharmacolog…
View article: Quantitative characterization of permeability heterogeneity of tight-sand reservoirs using nano-CT technology: A case study of the Yanchang Formation, Ordos Basin
Quantitative characterization of permeability heterogeneity of tight-sand reservoirs using nano-CT technology: A case study of the Yanchang Formation, Ordos Basin Open
The physical properties of hydrocarbon reservoirs are important factors affecting the percolation ability of the reservoirs. Tight-sand reservoirs exhibit complex pore throat connectivity due to the extensive development of micro- and nano…
View article: Elevated serum uric acid level correlates with the severity of renal histopathology in IgA nephropathy and establishment of a nomogram model
Elevated serum uric acid level correlates with the severity of renal histopathology in IgA nephropathy and establishment of a nomogram model Open
Background. IgA nephropathy (IgAN), the most common primary glomerulonephritis worldwide, is also a major cause of end stage renal disease (ESRD). We aimed to explore the relationship between the levels of serum uric acidand the degree of …
View article: Comparative analysis of morphologival parameters in isolated and fused L5 spondylolysis patients on the basis of CT features
Comparative analysis of morphologival parameters in isolated and fused L5 spondylolysis patients on the basis of CT features Open
View article: Comprehensive analysis of ESCRT transcriptome-associated signatures and identification of the regulatory role of LMO7-AS1 in osteosarcoma
Comprehensive analysis of ESCRT transcriptome-associated signatures and identification of the regulatory role of LMO7-AS1 in osteosarcoma Open
View article: Airway stenosis: classification, pathogenesis, and clinical management
Airway stenosis: classification, pathogenesis, and clinical management Open
Airway stenosis (AS) is a fibroinflammatory disease characterized by abnormal activation of fibroblasts and excessive synthesis of extracellular matrix, which has puzzled many doctors despite its relatively low prevalence. Traditional trea…
View article: Corrigendum to “Protective effects of Longhu Rendan on chronic liver injury and fibrosis in mice” [Liver Res. 6 (2022) 93–102]
Corrigendum to “Protective effects of Longhu Rendan on chronic liver injury and fibrosis in mice” [Liver Res. 6 (2022) 93–102] Open
View article: A Welding Defect Detection Algorithm Based on Deep Learning
A Welding Defect Detection Algorithm Based on Deep Learning Open
In order to meet the needs of process inspection technology for industrial equipment, image recognition technology based on deep learning has shown great potential in the field of welding defects. In this paper, an improved YOLOv8 algorith…
View article: Diagram-Driven Course Questions Generation
Diagram-Driven Course Questions Generation Open
View article: MRI-based radiomic nomogram for predicting disease-free survival in patients with locally advanced rectal cancer
MRI-based radiomic nomogram for predicting disease-free survival in patients with locally advanced rectal cancer Open
View article: Colorectal cancer screening using a multi-locus blood-based assay targeting circulating tumor DNA methylation: a cross-sectional study in an average-risk population
Colorectal cancer screening using a multi-locus blood-based assay targeting circulating tumor DNA methylation: a cross-sectional study in an average-risk population Open
View article: Comprehensive analysis of the diagnostic and therapeutic value, immune infiltration, and drug treatment mechanisms of GTSE1 in lung adenocarcinoma
Comprehensive analysis of the diagnostic and therapeutic value, immune infiltration, and drug treatment mechanisms of GTSE1 in lung adenocarcinoma Open
Objective The aim of this investigation was to assess the diagnostic and therapeutic efficacy of G2 and S-phase expressed 1 (GTSE1) in lung adenocarcinoma (LUAD), while examining its impact on immune infiltration and drug treatment mechani…
View article: Does hospital middle manager’s management competency contribute to organizational performance? A cross-sectional study from tertiary public hospitals in Sichuan Province
Does hospital middle manager’s management competency contribute to organizational performance? A cross-sectional study from tertiary public hospitals in Sichuan Province Open
Background With the continuous improvement of hospital management practices and dynamic changes in the external environment, efforts to improve hospital organizational performance have become increasingly challenging. The management compet…
View article: Fasting plasma glucose level and in-hospital cardiac arrest in patients with acute coronary syndrome: findings from the CCC-ACS project
Fasting plasma glucose level and in-hospital cardiac arrest in patients with acute coronary syndrome: findings from the CCC-ACS project Open
The study findings showed a positive correlation between FPG levels and a higher incidence of IHCA, irrespective of the presence of diabetes.
View article: The role of anxiety in the association between nutrition literacy and health-related quality of life among college students
The role of anxiety in the association between nutrition literacy and health-related quality of life among college students Open
The health-related quality of life (HRQOL) of college students is not promising and needs to be improved through effective interventions. This study aimed to investigate the associations of nutrition literacy (NL) with HRQOL and anxiety am…