James Liao
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View article: A novel methodological approach to understanding the cortical and subcortical effects of aerobic exercise in Parkinson’s disease
A novel methodological approach to understanding the cortical and subcortical effects of aerobic exercise in Parkinson’s disease Open
Introduction Aerobic exercise mitigates symptoms of Parkinson’s disease (PD) and may slow disease progression; however, the neural mechanisms underlying these improvements are not well understood. In this study, we discuss the methodology …
View article: A Case of Acute-Onset, Refractory Freezing of Gait Following Subthalamic Nucleus Deep Brain Stimulation Adjustment
A Case of Acute-Onset, Refractory Freezing of Gait Following Subthalamic Nucleus Deep Brain Stimulation Adjustment Open
Freezing of gait (FoG) is a disabling symptom of Parkinson's disease (PD) characterized by involuntary cessation/reduction. While deep brain stimulation (DBS) targeting the subthalamic nucleus (STN) effectively treats common PD symptoms su…
View article: An Experimental Approach for Investigating Freezing of Gait in Parkinson’s Disease Using Virtual Reality and Neural Sensing: A Pilot Study
An Experimental Approach for Investigating Freezing of Gait in Parkinson’s Disease Using Virtual Reality and Neural Sensing: A Pilot Study Open
Freezing of gait (FOG) is a disabling symptom associated with Parkinson’s disease (PD). Its understanding and effective treatment is compromised due to the difficulty in reliably triggering FOG in clinical and laboratory environments. The …
View article: Including individuals with Parkinson's disease and deep brain stimulation in rehabilitation trials: feasibility, challenges, and preliminary gait and postural stability results
Including individuals with Parkinson's disease and deep brain stimulation in rehabilitation trials: feasibility, challenges, and preliminary gait and postural stability results Open
Initial data suggest dual-task training is safe and feasible for PwPD with DBS. Having DBS presents unique challenges including advanced motor symptoms, autonomic dysfunction, and potential changes in DBS parameters, that impact interventi…
View article: Genetic Risk Factors in Normal Pressure Hydrocephalus: What We Know and What Is Next
Genetic Risk Factors in Normal Pressure Hydrocephalus: What We Know and What Is Next Open
Knowledge of the genetic factors in normal pressure hydrocephalus (NPH) is rapidly evolving, with significant advances in recent years. We conducted a systematic review examining genetic contributions to NPH risk. Ovid Embase, Ovid Medline…
View article: An augmented reality dual-task intervention improves postural stability in individuals with Parkinson’s disease
An augmented reality dual-task intervention improves postural stability in individuals with Parkinson’s disease Open
Improvements in postural stability, functional mobility, and turning under single- and dual-task conditions following traditional and DART DTT in individuals with PD indicate that cognitive-motor training can be used to effectively treat p…
View article: A Review on Response to Device-Aided Therapies Used in Monogenic Parkinsonism and GBA Variants Carriers: A Need for Guidelines and Comparative Studies
A Review on Response to Device-Aided Therapies Used in Monogenic Parkinsonism and GBA Variants Carriers: A Need for Guidelines and Comparative Studies Open
Parkinson’s disease (PD) is in some cases predisposed-or-caused by genetic variants, contributing to the expression of different phenotypes. Regardless of etiology, as the disease progresses, motor fluctuations and/or levodopa-induced dysk…
View article: Velocity neurons improve performance more than goal or position neurons do in a simulated closed-loop BCI arm-reaching task
Velocity neurons improve performance more than goal or position neurons do in a simulated closed-loop BCI arm-reaching task Open
Brain-Computer Interfaces (BCIs) that convert brain-recorded neural signals into intended movement commands could eventually be combined with Functional Electrical Stimulation to allow individuals with Spinal Cord Injury to regain effectiv…