Junpeng Chi
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View article: A systematic review and meta-analysis of the efficacy and safety of mirabegron vs. tamsulosin in alleviating double-J catheter related symptoms
A systematic review and meta-analysis of the efficacy and safety of mirabegron vs. tamsulosin in alleviating double-J catheter related symptoms Open
Background Currently, many clinicians use tamsulosin as a medication to alleviate symptoms following double J (DJ) stent insertion. With the emerging advantages of β -receptor agonists in relieving urinary tract spasms, the effectiveness o…
View article: Intensive care unit outcomes and prognostic factors of colorectal cancer
Intensive care unit outcomes and prognostic factors of colorectal cancer Open
BACKGROUND Colorectal cancer (CRC) is one of the most common cancers and CRC patients are among the most common intensive care unit (ICU) admitted cancer patients. However, their prognosis and evaluation methods are rarely studied. AIM To …
View article: MED6 as a prognostic biomarker for bladder cancer: Bioinformatics analysis
MED6 as a prognostic biomarker for bladder cancer: Bioinformatics analysis Open
View article: Placebo effect of sham acupuncture in patients with insomnia and influence of varying stimulation intensities and locations: A systematic review and meta-analysis
Placebo effect of sham acupuncture in patients with insomnia and influence of varying stimulation intensities and locations: A systematic review and meta-analysis Open
Sham acupuncture produces a measurable and relatively stable placebo effect in insomnia patients. The effectiveness varied across different sham protocols, with low-intensity stimulation and medium-frequency regimens (13-20 sessions) showi…
View article: The Efficacy and Safety of Daily Use of Tadalafil in Treatment of Premature Ejaculation: A Systematic Review and Meta-Analysis
The Efficacy and Safety of Daily Use of Tadalafil in Treatment of Premature Ejaculation: A Systematic Review and Meta-Analysis Open
The purpose of this meta-analysis was to evaluate the efficacy and safety of the once-daily use of 5 mg tadalafil in the treatment of patients with premature ejaculation. The databases MEDLINE/PubMed, EMBASE, and Cochrane Library from Janu…
View article: Intensive care unit outcomes and prognostic factors of esophageal cancer: A cross-sectional study in Chinese cancer-specialized hospitals
Intensive care unit outcomes and prognostic factors of esophageal cancer: A cross-sectional study in Chinese cancer-specialized hospitals Open
BACKGROUND Esophageal cancer patients had the highest intensive care unit (ICU) admitted rate in cancer patients. But their prognosis and evaluation methods were rarely studied. AIM To depict the short-term mortality outcome and identify t…
View article: Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats
Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats Open
Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with complex etiology. It is characterized by fibrosis of the tunica albuginea (TA), which may be accompanied by pain, deformity…
View article: A new predictive factor VGF based on IHC experiments, gene pathways and molecular functional groups for tumor immune microenvironment and prognosis of adrenocortical carcinoma
A new predictive factor VGF based on IHC experiments, gene pathways and molecular functional groups for tumor immune microenvironment and prognosis of adrenocortical carcinoma Open
Background Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with a poor prognosis, and its clinical management remains a significant challenge due to the high recurrence rates and limited treatment options. Despite advanc…
View article: Comparison of efficacy and safety of mirabegron and vibegron in the treatment of Overactive Bladder (OAB) in older women: A systematic review and meta-analysis
Comparison of efficacy and safety of mirabegron and vibegron in the treatment of Overactive Bladder (OAB) in older women: A systematic review and meta-analysis Open
Background After the introduction of anticholinergic drugs for the treatment of overactive bladder (OAB), the discovery of β-adrenergic agonists has helped reduce the side effects associated with the former. Currently, the two available me…
View article: Integrative Multi-Omics Mendelian Randomization Study Identifies Mitochondria-Related Genes as Novel Drivers of Bladder Cancer Pathogenesis and Therapeutic Targets
Integrative Multi-Omics Mendelian Randomization Study Identifies Mitochondria-Related Genes as Novel Drivers of Bladder Cancer Pathogenesis and Therapeutic Targets Open
View article: Evaluating the safety and effectiveness of α-blockers versus mirabegron for medical expulsive therapy in ureteral calculi: A Systematic review and meta-analysis
Evaluating the safety and effectiveness of α-blockers versus mirabegron for medical expulsive therapy in ureteral calculi: A Systematic review and meta-analysis Open
Introduction and aim The main categories of drugs employed for medical expulsive therapy in patients with ureteral calculi (UC) are alpha-blockers (α-B) and beta-adrenoceptor agonists. This meta-analysis evaluated the safety and effectiven…
View article: Research progress on the microbiota in bladder cancer tumors
Research progress on the microbiota in bladder cancer tumors Open
The microbiota, also referred to as the microbial community, is a crucial component of the human microenvironment. It is located predominantly in various organs, including the intestines, skin, oral cavity, respiratory tract, and reproduct…
View article: Comparative analysis of holmium: YAG laser internal urethrotomy versus Cold-Knife optical internal urethrotomy in the management of urethral stricture – a systematic review and meta-analysis
Comparative analysis of holmium: YAG laser internal urethrotomy versus Cold-Knife optical internal urethrotomy in the management of urethral stricture – a systematic review and meta-analysis Open
Objective: Urethral stricture management has posed enduring challenges in urology, demanding innovative and effective treatment modalities. This study addresses the persistent issues associated with urethral strictures, focusing on the com…
View article: Research advances in Peyronie’s disease: a comprehensive review on genomics, pathways, phenotypic manifestation, and therapeutic targets
Research advances in Peyronie’s disease: a comprehensive review on genomics, pathways, phenotypic manifestation, and therapeutic targets Open
Introduction Penile induration disease, commonly known as Peyronie’s disease (PD), is a connective tissue disorder that affects the penis, leading to the development of fibrous plaques, penile curvature, and erectile dysfunction. PD is a c…
View article: Evaluating the Safety and Effectiveness of α-Blockers Versus Mirabegron for Medical Expulsive Therapy in Ureteral Calculi: A Systematic Review and Meta-Analysis
Evaluating the Safety and Effectiveness of α-Blockers Versus Mirabegron for Medical Expulsive Therapy in Ureteral Calculi: A Systematic Review and Meta-Analysis Open
Introduction and Aim. The main categories of drugs employed for medical expulsive therapy in patients with ureteral calculi (UC) are alpha-blockers (α-B) and beta-adrenoceptor agonists. This meta-analysis evaluated the safety and effective…
View article: Efficacy of mirabegron for ureteral stones: a systematic review with meta-analysis of randomized controlled trials
Efficacy of mirabegron for ureteral stones: a systematic review with meta-analysis of randomized controlled trials Open
Background: Medical expulsive therapy demonstrates efficacy in managing ureteral stones in patients amenable to conservative interventions. This meta-analysis aims to evaluate the effectiveness of mirabegron in the treatment of ureteral st…
View article: The systematic review and meta-analysis evaluated the efficacy and safety of nefopam for catheter-related bladder discomfort based on randomized controlled trials
The systematic review and meta-analysis evaluated the efficacy and safety of nefopam for catheter-related bladder discomfort based on randomized controlled trials Open
Background: Catheter-related bladder discomfort (CRBD) is a frequent occurrence following urinary catheterization during surgical procedures, as well as a commonly experienced bladder pain syndrome after surgery. There have been various st…