Junren Wang
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View article: FXR shapes an immunosuppressive microenvironment in PD-L1lo/– non-small cell lung cancer by upregulating HVEM
FXR shapes an immunosuppressive microenvironment in PD-L1lo/– non-small cell lung cancer by upregulating HVEM Open
Immune checkpoint therapy has changed cancer treatment, including non-small cell lung cancer (NSCLC). The unresponsiveness of PD-L1lo/- tumors to anti-PD-1/PD-L1 immunotherapy is attributed to alternative immune evasion mechanisms that rem…
View article: Performance of self-performed SARS-CoV-2 rapid antigen test: a systematic review and meta-analysis
Performance of self-performed SARS-CoV-2 rapid antigen test: a systematic review and meta-analysis Open
Background The aim of this study was to investigate the accuracy of self-tested SARS-CoV-2 rapid antigen tests. Methods Databases of Pubmed, Embase, and Cochrane Library were searched for original studies investigating accuracy of self-tes…
View article: Association of psychosocial state with subsequent risk of dementia: a prospective cohort study based on the UK Biobank
Association of psychosocial state with subsequent risk of dementia: a prospective cohort study based on the UK Biobank Open
Unfavorable psychosocial patterns are associated with an increased risk of dementia, independent of genetic susceptibility. The findings highlight the importance of surveillance and prevention of cognitive decline among individuals with su…
View article: The association of psychological and trauma-related factors with biological and facial aging acceleration: evidence from the UK Biobank
The association of psychological and trauma-related factors with biological and facial aging acceleration: evidence from the UK Biobank Open
Our study demonstrated significant associations of psycho-trauma factors with both biological and facial aging acceleration. The differential aging consequences observed among ACEs exposed individuals with and without psychopathology promp…
View article: Risk of Cardiovascular Disease Hospitalization After Common Psychiatric Disorders: Analyses of Disease Susceptibility and Progression Trajectory in the UK Biobank
Risk of Cardiovascular Disease Hospitalization After Common Psychiatric Disorders: Analyses of Disease Susceptibility and Progression Trajectory in the UK Biobank Open
Whether associations between psychiatric disorders and hospitalization for cardiovascular diseases (CVDs) can be modified by disease susceptibility and the temporal pattern of these associated CVDs remain unknown. In our study, we conducte…
View article: Classification of hepatic echinococcosis based on ultrasound using radiomics approaches including machine and deep learning models and Compared with primary medical workers: a retrospective, large-scale, dual-center application study
Classification of hepatic echinococcosis based on ultrasound using radiomics approaches including machine and deep learning models and Compared with primary medical workers: a retrospective, large-scale, dual-center application study Open
Background Hepatic echinococcosis (HE) is a life-threatening parasitic disease that requires precise diagnosis and proper treatment, and ultrasonography is recommended to diagnosis. However, challenges remain with primary medical workers i…
View article: Farnesoid X receptor promotes non-small cell lung cancer metastasis by activating Jak2/STAT3 signaling via transactivation of IL-6ST and IL-6 genes
Farnesoid X receptor promotes non-small cell lung cancer metastasis by activating Jak2/STAT3 signaling via transactivation of IL-6ST and IL-6 genes Open
View article: Childhood maltreatment and risk of endocrine diseases: an exploration of mediating pathways using sequential mediation analysis
Childhood maltreatment and risk of endocrine diseases: an exploration of mediating pathways using sequential mediation analysis Open
Background Adverse childhood experiences (ACEs), including childhood maltreatment, have been linked with increased risk of diabetes and obesity during adulthood. A comprehensive assessment on the associations between childhood maltreatment…
View article: Identification of ipsilateral supraclavicular lymph node metastasis in breast cancer based on LASSO regression with a high penalty factor
Identification of ipsilateral supraclavicular lymph node metastasis in breast cancer based on LASSO regression with a high penalty factor Open
Aiming at the problems of small sample size and large feature dimension in the identification of ipsilateral supraclavicular lymph node metastasis status in breast cancer using ultrasound radiomics, an optimized feature combination search …
View article: Cohort profile: the China surgery and anesthesia cohort (CSAC)
Cohort profile: the China surgery and anesthesia cohort (CSAC) Open
The China Surgery and Anaesthesia Cohort (CSAC) study was launched in July 2020 and is an ongoing prospective cohort study recruiting patients aged 40–65 years who underwent elective surgeries with general anaesthesia across four medical c…
View article: Unravelling International Students' Preferences in Embracing Malaysian Cuisine: A Pilot Study
Unravelling International Students' Preferences in Embracing Malaysian Cuisine: A Pilot Study Open
This pilot study aims to investigate the preferences of international students in embracing Malaysian cuisine during their tenure at local university. Students frequently experience difficulties in their social and academic environments. N…
View article: Wear Anomaly Detection Method of Tunnel Boring Machine Disc Cutters Based on Anomaly-Attention Improved Long Short-Term Memory Autoencoder
Wear Anomaly Detection Method of Tunnel Boring Machine Disc Cutters Based on Anomaly-Attention Improved Long Short-Term Memory Autoencoder Open
View article: Physical exercise/sports ameliorate the internet addiction from college students during the pandemic of COVID-19 in China
Physical exercise/sports ameliorate the internet addiction from college students during the pandemic of COVID-19 in China Open
The rapid advancement of modern technology has significantly driven progress in various IT-related activities, resulting in a substantial increase in internet penetration rates, particularly among college students. The utilization of the i…
View article: Tuning the Inter‐Nanoplatelet Distance and Coupling Strength by Thermally Induced Ligand Decomposition
Tuning the Inter‐Nanoplatelet Distance and Coupling Strength by Thermally Induced Ligand Decomposition Open
CdSe nanoplatelets (NPLs) are promising 2D semiconductors for optoelectronic applications, in which efficient charge transport properties are desirable. It is reported that thermal annealing constitutes an effective strategy to control the…
View article: Frontispiece: Emergence of a Lanthanide Chalcogenide as an Ideal Scintillator for a Flexible X‐ray Detector
Frontispiece: Emergence of a Lanthanide Chalcogenide as an Ideal Scintillator for a Flexible X‐ray Detector Open
Scintillators. In their Communication (e202306465), Xing Dai, Shu-Xian Hu, Yaxing Wang et al. report the chalcogenide-based scintillator LaCsSiS4:1%Ce3+ showing multiple properties, such as high light yield, fast decay time, low detection …
View article: Frontispiz: Emergence of a Lanthanide Chalcogenide as an Ideal Scintillator for a Flexible X‐ray Detector
Frontispiz: Emergence of a Lanthanide Chalcogenide as an Ideal Scintillator for a Flexible X‐ray Detector Open
Scintillators. In their Communication (e202306465), Xing Dai, Shu-Xian Hu, Yaxing Wang et al. report the chalcogenide-based scintillator LaCsSiS4:1%Ce3+ showing multiple properties, such as high light yield, fast decay time, low detection …
View article: Clinical Characteristics and Economic Burden of Asthma in China: A Multicenter Retrospective Study
Clinical Characteristics and Economic Burden of Asthma in China: A Multicenter Retrospective Study Open
Asthma is a common chronic airway inflammation that produces a healthcare burden on the economy. We aim to obtain a better understanding of the clinical status and disease burden of patients with asthma in China. A retrospective study was …
View article: An artificial intelligence based news feature mining system based on the Internet of Things and multi-sensor fusion
An artificial intelligence based news feature mining system based on the Internet of Things and multi-sensor fusion Open
The application of Internet of Things (IoT) technology in news media communication has significantly enhanced the effectiveness and coverage of news data releases. However, as the scale of news data continues to grow, traditional IoT appro…
View article: The impact of COVID-19 lockdown on nursing higher education at Chengdu University
The impact of COVID-19 lockdown on nursing higher education at Chengdu University Open
Background To combat/control the COVID-19 pandemic, a complete lockdown was implemented in China for almost 6 months during 2020. Purpose To determine the impact of a long-term lockdown on the academic performance of first-year nursing stu…
View article: 60‐3: <i>Invited Paper:</i> Liquid Crystal Optics for AR/VR/MR Near Eye Displays
60‐3: <i>Invited Paper:</i> Liquid Crystal Optics for AR/VR/MR Near Eye Displays Open
Liquid crystal optics are highly favorable for AR/VR/MR near‐eye displays because of the capability of modulating polarization and phase in an ultra‐compact profile. In this presentation, we discuss state‐of‐the‐art LC polarization hologra…
View article: Automated detection of hippocampal sclerosis using real-world clinical MRI images
Automated detection of hippocampal sclerosis using real-world clinical MRI images Open
Background Hippocampal sclerosis (HS) is the most common pathological type of temporal lobe epilepsy (TLE) and one of the important surgical markers. Currently, HS is mainly diagnosed manually by radiologists based on visual inspection of …
View article: Immune checkpoint inhibitor-associated toxicity in advanced non-small cell lung cancer: An updated understanding of risk factors
Immune checkpoint inhibitor-associated toxicity in advanced non-small cell lung cancer: An updated understanding of risk factors Open
Immune checkpoint inhibitors (ICIs), such as programmed death-1 (PD-1), programmed death-ligand 1 (PD-L1), cytotoxic T lymphocyte antigen 4 (CTLA-4) antibodies, etc, have revolutionized cancer treatment strategies, including non-small cell…
View article: Prediction of Suicidal Behaviors in the Middle-aged Population: Machine Learning Analyses of UK Biobank
Prediction of Suicidal Behaviors in the Middle-aged Population: Machine Learning Analyses of UK Biobank Open
Background Suicidal behaviors, including suicide deaths and attempts, are major public health concerns. However, previous suicide models required a huge amount of input features, resulting in limited applicability in clinical practice. Obj…
View article: Trends in incident diagnoses and drug prescriptions for anxiety and depression during the COVID-19 pandemic: an 18-month follow-up study based on the UK Biobank
Trends in incident diagnoses and drug prescriptions for anxiety and depression during the COVID-19 pandemic: an 18-month follow-up study based on the UK Biobank Open
View article: Exploring the relationship between post-contrast acute kidney injury and different baseline creatinine standards: A retrospective cohort study
Exploring the relationship between post-contrast acute kidney injury and different baseline creatinine standards: A retrospective cohort study Open
Objective According to previous studies, the incidence of post-contrast acute kidney injury(PC-AKI) in diabetic is far higher than that in the general population. Therefore, we explored the relationship between the incidence of PC-AKI and …
View article: Self-standing TiC-modified carbon fibre electrodes derived from cellulose and their use as an ultrahigh efficiency lithium metal anode
Self-standing TiC-modified carbon fibre electrodes derived from cellulose and their use as an ultrahigh efficiency lithium metal anode Open
A self-standing three-dimensional TiC-modified carbon fibre (TiC@C) network has been fabricated by carbothermal reduction and demonstrated to be effective as a host for a dendrite-free metallic lithium anode.
View article: Comparison of dyslipidemia incidence in Chinese early-stage breast cancer patients following different endocrine therapies: A population-based cohort study
Comparison of dyslipidemia incidence in Chinese early-stage breast cancer patients following different endocrine therapies: A population-based cohort study Open
Background There is lack of large-scale real-world research evidence showing the impact of endocrine therapy on blood lipids in Chinese breast cancer patients, especially those with premenopausal breast cancer. Based on a large breast canc…
View article: The role of genetic predisposition in cardiovascular risk after cancer diagnosis: a matched cohort study of the UK Biobank
The role of genetic predisposition in cardiovascular risk after cancer diagnosis: a matched cohort study of the UK Biobank Open
View article: Solution‐Processed Wafer‐Scale Ag<sub>2</sub>S Thin Films: Synthesis and Excellent Charge Transport Properties
Solution‐Processed Wafer‐Scale Ag<sub>2</sub>S Thin Films: Synthesis and Excellent Charge Transport Properties Open
Monoclinic α‐Ag 2 S is an intriguing member of transition metal sulfides with great potential for all‐inorganic flexible optoelectronics and thermoelectrics. Fabrication of large‐area, high‐quality α‐Ag 2 S thin films and understanding the…
View article: The carbon footprint of cold chain food flows in the United States
The carbon footprint of cold chain food flows in the United States Open
The food system is an important contributor to carbon dioxide (CO 2 ) emissions. The refrigerated food supply chain is an energy-intensive, nutritious and high-value part of the food system, making it particularly important to consider. In…