Juntaro Matsuzaki
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View article: Functional biomarkers for endometriosis targeting small RNAs in bacterial extracellular vesicles
Functional biomarkers for endometriosis targeting small RNAs in bacterial extracellular vesicles Open
Extracellular vesicles (EVs) are secreted from mammalian cells and bacteria and are involved in disease pathogenesis. Recently, bacterial factors have been linked to the pathogenesis of endometriosis. Therefore, identifying host-bacterial …
View article: A Case Report of Autoimmune Gastritis Associated With Polyendocrine Syndrome Type III Mimicking Refractory H. pylori Infection
A Case Report of Autoimmune Gastritis Associated With Polyendocrine Syndrome Type III Mimicking Refractory H. pylori Infection Open
A 60-year-old woman had persistent positive urea breath test (UBT) results despite three courses of Helicobacter pylori (H. pylori) eradication therapy. Endoscopy revealed extensive atrophic gastritis with a characteristic "r…
View article: Association of KRAS variants with survival and therapeutic outcomes in biliary tract cancers
Association of KRAS variants with survival and therapeutic outcomes in biliary tract cancers Open
KRAS variants were significantly associated with poor prognosis and unfavorable therapeutic outcomes in BTC patients and may serve as potential prognostic and predictive factors.
View article: Environmental factors in gastric carcinogenesis and preventive intervention strategies
Environmental factors in gastric carcinogenesis and preventive intervention strategies Open
Gastric cancer, a significant global health concern, arises from a complex interplay of genetic and environmental factors. Helicobacter pylori ( H. pylori ) infection is a major risk factor that can be mitigated through eradication strateg…
View article: Poly(N-isopropylacrylamide)-grafted Ti–6Al–4V alloy for reusable temperature-responsive cell-culture surfaces
Poly(N-isopropylacrylamide)-grafted Ti–6Al–4V alloy for reusable temperature-responsive cell-culture surfaces Open
View article: Impact of strength training of large muscle groups on quality of life
Impact of strength training of large muscle groups on quality of life Open
Muscle-strengthening activities reduce the risk of various diseases and promote overall health. Physical activities targeting large muscle groups, such as weightlifting or resistance exercises, provide an additional health benefit. The pre…
View article: Upper gastrointestinal triple stenosis in a patient with trisomy 17p syndrome: Case report and literature review
Upper gastrointestinal triple stenosis in a patient with trisomy 17p syndrome: Case report and literature review Open
Upper gastrointestinal stenosis, which can be congenital or acquired, can lead to dysphagia. The association between trisomy 17p syndrome, a rare chromosomal abnormality, and upper gastrointestinal stenosis is unclear. A 20‐year‐old man di…
View article: 10048- COT-5 DEVELOPMENT OF A DIAGNOSTIC MODEL FOR GLIOMAS USING SERUM MICRO RNA
10048- COT-5 DEVELOPMENT OF A DIAGNOSTIC MODEL FOR GLIOMAS USING SERUM MICRO RNA Open
BACKGROUND MicroRNAs (miRNAs) are non-coding RNAs consisting of approximately 20 base pairs. Several studies have reported the usefulness of serum miRNAs in the diagnosis of gliomas. However, the results differ among studies, and reproduci…
View article: Circulating serum <scp>miRNAs</scp> predict response to platinum chemotherapy in high‐grade serous ovarian cancer
Circulating serum <span>miRNAs</span> predict response to platinum chemotherapy in high‐grade serous ovarian cancer Open
Background Platinum chemotherapy is the cornerstone of treatment for high‐grade serous ovarian cancer (HGSOC); however, validated biomarkers that can accurately predict platinum response are lacking. Based on their roles in the underlying …
View article: Macrophage-depleted young mice are beneficial in vivo models to assess the translocation of Klebsiella pneumonia from the gastrointestinal tract to the liver in the elderly
Macrophage-depleted young mice are beneficial in vivo models to assess the translocation of Klebsiella pneumonia from the gastrointestinal tract to the liver in the elderly Open
Pathobionts are commensal intestinal microbiota capable of causing systemic infections under specific conditions, such as environmental changes or aging. However, it is unclear how pathobionts are recognized by the intestinal mucosal immun…
View article: A comparative study on dietary diversity and gut microbial diversity in children with autism spectrum disorder, attention‐deficit hyperactivity disorder, their neurotypical siblings, and non‐related neurotypical volunteers: a cross‐sectional study
A comparative study on dietary diversity and gut microbial diversity in children with autism spectrum disorder, attention‐deficit hyperactivity disorder, their neurotypical siblings, and non‐related neurotypical volunteers: a cross‐sectional study Open
Background Previous research has shown a significant link between gut microbiota in children with autism spectrum disorder (ASD) and attention‐deficit hyperactivity disorder (ADHD). However, much remains unknown because of the heterogeneit…
View article: Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibitor PRI-724 in patients with liver cirrhosis
Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibitor PRI-724 in patients with liver cirrhosis Open
View article: Intestinal metabolites predict treatment resistance of patients with depression and anxiety
Intestinal metabolites predict treatment resistance of patients with depression and anxiety Open
Background The impact of the gut microbiota on neuropsychiatric disorders has gained much attention in recent years; however, comprehensive data on the relationship between the gut microbiome and its metabolites and resistance to treatment…
View article: Circulating serum miRNAs predict response to platinum chemotherapy in high-grade serous ovarian cancer
Circulating serum miRNAs predict response to platinum chemotherapy in high-grade serous ovarian cancer Open
Background Platinum chemotherapy is the cornerstone of treatment for high-grade serous ovarian cancer (HGSOC); however, validated biomarkers that can accurately predict platinum response are lacking. Based on their roles in the underlying …
View article: Development of reusable PIPAAm grafted Ti-6Al-4V cell culture surface
Development of reusable PIPAAm grafted Ti-6Al-4V cell culture surface Open
View article: Identifying high-grade serous ovarian carcinoma–specific extracellular vesicles by polyketone-coated nanowires
Identifying high-grade serous ovarian carcinoma–specific extracellular vesicles by polyketone-coated nanowires Open
Cancer cell–derived extracellular vesicles (EVs) have unique protein profiles, making them promising targets as disease biomarkers. High-grade serous ovarian carcinoma (HGSOC) is the deadly subtype of epithelial ovarian cancer, and we aime…
View article: Evidence for in vitro extensive proliferation of adult hepatocytes and biliary epithelial cells
Evidence for in vitro extensive proliferation of adult hepatocytes and biliary epithelial cells Open
View article: Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver
Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver Open
Immunosenescence refers to the development of weakened and/or dysfunctional immune responses associated with aging. Several commensal bacteria can be pathogenic in immunosuppressed individuals. Although Klebsiella pneumoniae is a commensal…
View article: A validation study for the utility of serum microRNA as a diagnostic and prognostic marker in patients with osteosarcoma
A validation study for the utility of serum microRNA as a diagnostic and prognostic marker in patients with osteosarcoma Open
In our previous study, osteosarcoma advanced locally, and metastasis was promoted through the secretion of large number of small extracellular vesicles, followed by suppressing osteoclastogenesis via the upregulation of microRNA (miR)-146a…
View article: Data from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer
Data from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer Open
Purpose:The high false-positive rate of prostate-specific antigen (PSA) may lead to unnecessary prostate biopsies. Therefore, the United States Preventive Services Task Force recommends that decisions regarding PSA-based screening of prost…
View article: Data from Serum miRNA–based Prediction of Axillary Lymph Node Metastasis in Breast Cancer
Data from Serum miRNA–based Prediction of Axillary Lymph Node Metastasis in Breast Cancer Open
Purpose:Sentinel lymph node biopsy (SLNB) is the gold-standard procedure for evaluating axillary lymph node (ALN) status in patients with breast cancer. However, the morbidity of SLNB is not negligible, and the procedure is invasive for pa…
View article: Data from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer
Data from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer Open
Purpose:The high false-positive rate of prostate-specific antigen (PSA) may lead to unnecessary prostate biopsies. Therefore, the United States Preventive Services Task Force recommends that decisions regarding PSA-based screening of prost…
View article: Table S1, Table S2, Table S3, Table S4, Table S5, Table S6, Table S7, Table S8, Table S9, Table S10, Table S11, Figure S1, Figure S2, Figure S3, Text from Serum miRNA–based Prediction of Axillary Lymph Node Metastasis in Breast Cancer
Table S1, Table S2, Table S3, Table S4, Table S5, Table S6, Table S7, Table S8, Table S9, Table S10, Table S11, Figure S1, Figure S2, Figure S3, Text from Serum miRNA–based Prediction of Axillary Lymph Node Metastasis in Breast Cancer Open
Table S1. Definition criteria of categorical variables for logistic-LASSO regression analysis Table S2. Clinicopathological characteristics of patients with benign breast diseases Table S3. Clinicopathological characteristics of patients s…
View article: Supplementary text from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer
Supplementary text from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer Open
Supplementary text
View article: Figure S1-3, Table S1-4 from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer
Figure S1-3, Table S1-4 from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer Open
Figure S1-3, Table S1-4
View article: Table S1, Table S2, Table S3, Table S4, Table S5, Table S6, Table S7, Table S8, Table S9, Table S10, Table S11, Figure S1, Figure S2, Figure S3, Text from Serum miRNA–based Prediction of Axillary Lymph Node Metastasis in Breast Cancer
Table S1, Table S2, Table S3, Table S4, Table S5, Table S6, Table S7, Table S8, Table S9, Table S10, Table S11, Figure S1, Figure S2, Figure S3, Text from Serum miRNA–based Prediction of Axillary Lymph Node Metastasis in Breast Cancer Open
Table S1. Definition criteria of categorical variables for logistic-LASSO regression analysis Table S2. Clinicopathological characteristics of patients with benign breast diseases Table S3. Clinicopathological characteristics of patients s…
View article: Supplementary text from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer
Supplementary text from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer Open
Supplementary text
View article: Figure S1-3, Table S1-4 from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer
Figure S1-3, Table S1-4 from Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer Open
Figure S1-3, Table S1-4
View article: Data from Serum miRNA–based Prediction of Axillary Lymph Node Metastasis in Breast Cancer
Data from Serum miRNA–based Prediction of Axillary Lymph Node Metastasis in Breast Cancer Open
Purpose:Sentinel lymph node biopsy (SLNB) is the gold-standard procedure for evaluating axillary lymph node (ALN) status in patients with breast cancer. However, the morbidity of SLNB is not negligible, and the procedure is invasive for pa…
View article: Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont,<i>Klebsiella pneumoniae</i>, to the liver
Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont,<i>Klebsiella pneumoniae</i>, to the liver Open
Immunosenescence refers to the development of weakened and/or dysfunctional immune responses associated with aging. Several commensal bacteria can be pathogenic in immunosuppressed individuals. Although Klebsiella pneumoniae is a commensal…