Junwei Gao
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View article: Classification of internal carotid artery aberrations based on CTA imaging: evaluating the risk of ICA injury in the transoral approach to upper cervical surgery
Classification of internal carotid artery aberrations based on CTA imaging: evaluating the risk of ICA injury in the transoral approach to upper cervical surgery Open
Aberrations in the course of the ICA at the upper cervical level are relatively common, presenting a potential risk of ICA injury during the transoral approach for upper cervical surgery. Therefore, our classification of ICA aberrations ba…
View article: The association between procrastination and negative emotions in healthy individuals: a systematic review and meta-analysis
The association between procrastination and negative emotions in healthy individuals: a systematic review and meta-analysis Open
Introduction The widespread recognition of the link between procrastination and negative emotions is accompanied by a need for greater clarity regarding the underlying mechanisms of this connection. This study aims to systematically review…
View article: METTL16 promotes osteosarcoma progression by inducing m6A methylation of the UBE3A and Notch signaling pathway
METTL16 promotes osteosarcoma progression by inducing m6A methylation of the UBE3A and Notch signaling pathway Open
Background: N6-methyladenosine (m6A) methylation plays a key role in osteosarcoma (OS) progression. This study aimed to elucidate the function and mechanism of methyltransferase 16 (METTL16), an m6A methyltransferase, in OS progression. Re…
View article: Transoral Approach with Reverse Pedicle Screw Technique for the Treatment of Chronic Levine-Edwards Type III Hangman’s Fracture: A Case Report, Surgical Technique, and Literature Review
Transoral Approach with Reverse Pedicle Screw Technique for the Treatment of Chronic Levine-Edwards Type III Hangman’s Fracture: A Case Report, Surgical Technique, and Literature Review Open
Background This report navigated transoral anterior pedicle screw technique achieved secure fixation for unstable hangman's fracture. It circumvented posterior approach risks and anterior contamination concerns. This offers a paradigm for …
View article: Therapeutic potential of natural medicines in diabetic kidney disease: restoring lipid homeostasis via lipophagy modulation
Therapeutic potential of natural medicines in diabetic kidney disease: restoring lipid homeostasis via lipophagy modulation Open
Diabetic kidney disease (DKD), one of the most prevalent microvascular complications of diabetes mellitus, is characterized by a complex pathogenesis in which lipid metabolism dysregulation plays a central role. Increasing evidence indicat…
View article: Exercise training for myocardial ischemia reperfusion injury: Mechanism and clinical practice (Review)
Exercise training for myocardial ischemia reperfusion injury: Mechanism and clinical practice (Review) Open
Myocardial ischemia reperfusion injury (MIRI) remains a key and difficult issue in the field of cardiovascular diseases, and its pathogenesis involves multiple aspects. Exercise can effectively improve MIRI, and the mechanisms include redu…
View article: Optimizing scheduling and bunkering decision for tramp shipping fleet under stochastic demand and bunker prices
Optimizing scheduling and bunkering decision for tramp shipping fleet under stochastic demand and bunker prices Open
The operational decisions faced by tramp shipping fleet operators are crucial, particularly in the current volatile global economic and trade environment. Navigating through uncertain market conditions poses a significant challenge for ope…
View article: The role of natural products in improving lipid metabolism disorder-induced mitochondrial dysfunction of diabetic kidney disease
The role of natural products in improving lipid metabolism disorder-induced mitochondrial dysfunction of diabetic kidney disease Open
Diabetic Kidney Disease (DKD) is one of the most common microvascular complications of diabetes mellitus and an important cause of end-stage renal disease, with a complex pathogenesis and a lack of effective treatment. Lipid metabolism dis…
View article: The relationship between physical activity, life satisfaction, emotional regulation, and physical self esteem among college students
The relationship between physical activity, life satisfaction, emotional regulation, and physical self esteem among college students Open
The satisfaction with life among college students is a multifaceted phenomenon influenced by various factors. This research investigates the influence of physical activity on the life satisfaction of college students, with a particular foc…
View article: Ovarian teratoma leading to colonic intussusception: a case report
Ovarian teratoma leading to colonic intussusception: a case report Open
Intussusception in adults is relatively rare compared to that in children and is typically caused by underlying benign or malignant intestinal diseases. We report a case of a 40-year-old female who presented with colonic intussusception an…
View article: The miR-941/FOXN4/TGF-β feedback loop induces N2 polarization of neutrophils and enhances tumor progression of lung adenocarcinoma
The miR-941/FOXN4/TGF-β feedback loop induces N2 polarization of neutrophils and enhances tumor progression of lung adenocarcinoma Open
Background Lung adenocarcinoma (LUAD) is a major subtype of lung cancer and one of the deadliest cancers in humans. Dysregulation of miRNA activity in tumor-associated neutrophils (TANs) in the tumor microenvironment plays an important rol…
View article: Impact of Comorbidities on Patients With Waldenström Macroglobulinemia in Taiwan: A Multicenter Study
Impact of Comorbidities on Patients With Waldenström Macroglobulinemia in Taiwan: A Multicenter Study Open
PURPOSE Comorbidities adversely affect the prognosis of several low-grade B-cell lymphomas, yet their influence in Waldenström macroglobulinemia (WM) remains unexplored. This study aimed to comprehensively evaluate the clinical characteris…
View article: The study of the association between exercise motivation and cardiorespiratory fitness in young students: a systematic review and meta-analysis
The study of the association between exercise motivation and cardiorespiratory fitness in young students: a systematic review and meta-analysis Open
Background In recent years, many studies have shown that exercise motivation is essential for encouraging students to engage in physical activities. Cardiorespiratory function, which is closely related to cardiorespiratory fitness, plays a…
View article: Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly
Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly Open
The mitochondrial calcium uniporter (MCU) complex mediates Ca 2+ entry into mitochondria, which plays a crucial role in regulating cellular energy metabolism and apoptosis. Dysregulation of MCU is implicated in various diseases, such as ne…
View article: Development and validation of a prediction model for acute kidney injury following cardiac valve surgery
Development and validation of a prediction model for acute kidney injury following cardiac valve surgery Open
Background Acute kidney injury (AKI) often accompanies cardiac valve surgery, and worsens patient outcome. The aim of our study is to identify preoperative and intraoperative independent risk factors for AKI in patients undergoing cardiac …
View article: Minocycline Ameliorates Staphylococcus aureus-Induced Neuroinflammation and Anxiety-like Behaviors by Regulating the TLR2 and STAT3 Pathways in Microglia
Minocycline Ameliorates Staphylococcus aureus-Induced Neuroinflammation and Anxiety-like Behaviors by Regulating the TLR2 and STAT3 Pathways in Microglia Open
Background: Anxiety disorders are the most common mental illnesses. S. aureus is a Gram-positive opportunistic pathogen most commonly associated with anxiety-like behaviors. Minocycline ameliorates Gram-negative bacterial LPS-induced anxie…
View article: Comparison of ciprofol versus propofol for the induction of patients with valve stenosis undergoing valve surgery: A prospective, randomized, controlled trial
Comparison of ciprofol versus propofol for the induction of patients with valve stenosis undergoing valve surgery: A prospective, randomized, controlled trial Open
Background: Ciprofol(HSK3486), a novel 2,6-disubstituted phenol derivative, is a new intravenous anesthetic compound with a similar chemical structure to propofol. The aim of this study was to investigate whether the induction of anesthesi…
View article: Volatile organic compounds (VOC) metabolites in urine are associated with increased systemic inflammation levels, and smokers are identified as a vulnerable population
Volatile organic compounds (VOC) metabolites in urine are associated with increased systemic inflammation levels, and smokers are identified as a vulnerable population Open
This study demonstrated a strong link between urinary VOC metabolites and increased systemic inflammation, and smokers were more susceptible. Our findings highlighted the significance of reducing VOC exposure to mitigate the inflammation l…
View article: HelloMeme: Integrating Spatial Knitting Attentions to Embed High-Level and Fidelity-Rich Conditions in Diffusion Models
HelloMeme: Integrating Spatial Knitting Attentions to Embed High-Level and Fidelity-Rich Conditions in Diffusion Models Open
We propose an effective method for inserting adapters into text-to-image foundation models, which enables the execution of complex downstream tasks while preserving the generalization ability of the base model. The core idea of this method…
View article: Berberine is a novel mitochondrial calcium uniporter (MCU) inhibitor that disrupts MCU-EMRE assembly
Berberine is a novel mitochondrial calcium uniporter (MCU) inhibitor that disrupts MCU-EMRE assembly Open
Summary The mitochondrial calcium uniporter (MCU) complex mediates Ca 2+ entry into mitochondrial, which plays a crucial role in regulating cellular energy metabolism and apoptosis. Dysregulation of MCU is implicated in various diseases, s…
View article: The risk factors of postoperative hypoxemia in patients with Stanford type A acute aortic dissection
The risk factors of postoperative hypoxemia in patients with Stanford type A acute aortic dissection Open
Hypoxemia is one of the most common complications in patients after Stanford type A acute aortic dissection surgery. The aim of this study was to investigate the association of circulating ANG II level with postoperative hypoxemia and to i…
View article: Effects of primary angle-closure glaucoma on interhemispheric functional connectivity
Effects of primary angle-closure glaucoma on interhemispheric functional connectivity Open
Background Previous studies on primary angle-closure glaucoma (PACG) primarily focused on local brain regions or global abnormal brain activity; however, the alteration of interhemispheric functional homotopy and its possible cause of brai…
View article: Valproic acid exposure decreases neurogenic potential of outer radial glia in human brain organoids
Valproic acid exposure decreases neurogenic potential of outer radial glia in human brain organoids Open
Valproic acid (VPA) exposure during pregnancy leads to a higher risk of autism spectrum disorder (ASD) susceptibility in offspring. Human dorsal forebrain organoids were used to recapitulate course of cortical neurogenesis in the developin…