Junwei Lian
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View article: Case Report: Metastasis to pleura and mediastinal lymph nodes from breast secretory carcinoma: 10 years follow-up
Case Report: Metastasis to pleura and mediastinal lymph nodes from breast secretory carcinoma: 10 years follow-up Open
Breast secretory carcinoma (BSC) is a rare low-grade malignancy that frequently exhibits the ETV6::NTRK3 fusion gene and rarely presents with distant metastasis. In this report, we describe a case of 72-year-old female diagnosed with BSC, …
View article: Univariate and Multivariate Pattern Analysis Reveals the Effects of Negative Body Image at Fatness on Food-Related Inhibitory Control
Univariate and Multivariate Pattern Analysis Reveals the Effects of Negative Body Image at Fatness on Food-Related Inhibitory Control Open
Background/Objectives: Perceptions of obesity critically influence people’s eating behaviors and responses to food stimuli. However, few studies have investigated the impact of negative body perception on behavioral and neural responses to…
View article: Yuyang Decoction Regulates Macrophage Polarization and Repairs the Intestinal Mucosal Barrier via the TLRs/Tollip Signaling Pathway
Yuyang Decoction Regulates Macrophage Polarization and Repairs the Intestinal Mucosal Barrier via the TLRs/Tollip Signaling Pathway Open
YYD alleviates DSS-induced colitis by enhancing intestinal barrier repair and modulating immune responses. Its therapeutic effect may involve activation of the Tollip signaling pathway, which inhibits pro-inflammatory M1-like macrophage di…
View article: Electrophysiological Characteristics of Inhibitive Control for Adults with Different Physiological or Psychological Obesity
Electrophysiological Characteristics of Inhibitive Control for Adults with Different Physiological or Psychological Obesity Open
Individuals exhibiting high scores on the fatness subscale of the negative-physical-self scale (NPSS-F) are characterized by heightened preoccupation with body fat accompanied by negative body image perceptions, often leading to excessive …
View article: Ebf1 Is Involved in Primitive Myelopoiesis and Contributes in Leukemia Pathogenesis
Ebf1 Is Involved in Primitive Myelopoiesis and Contributes in Leukemia Pathogenesis Open
Acute myeloid leukemia (AML) is caused by the abnormal proliferation and differentiation of a clonal population of myeloid progenitors. EBF1 is a key transcriptional factor in regulating hematopoiesis and has been linked to acute lymphobla…
View article: Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma
Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma Open
Bruton's tyrosine kinase (BTK) is a proven target in mantle cell lymphoma (MCL), an aggressive subtype of non-Hodgkin lymphoma. However, resistance to BTK inhibitors is a major clinical challenge. We here report that MALT1 is one of the to…
View article: Gfi1aa/Lsd1 Facilitates Hemangioblast Differentiation Into Primitive Erythrocytes by Targeting etv2 and sox7 in Zebrafish
Gfi1aa/Lsd1 Facilitates Hemangioblast Differentiation Into Primitive Erythrocytes by Targeting etv2 and sox7 in Zebrafish Open
The first wave of hematopoiesis is the primitive hematopoiesis, which produces embryonic erythroid and myeloid cells. Primitive erythrocytes are thought to be generated from bipotent hemangioblasts, but the molecular basis remains unclear.…
View article: Genetic and epigenetic orchestration of Gfi1aa-Lsd1-<i>cebpa</i> in zebrafish neutrophil development
Genetic and epigenetic orchestration of Gfi1aa-Lsd1-<i>cebpa</i> in zebrafish neutrophil development Open
Neutrophils are the most abundant vertebrate leukocytes and they are essential to host defense. Despite extensive investigation, the molecular network controlling neutrophil differentiation remains incompletely understood. GFI1 is associat…
View article: Alas1 is essential for neutrophil maturation in zebrafish
Alas1 is essential for neutrophil maturation in zebrafish Open
Neutrophils play essential roles in innate immunity and are the first responders to kill foreign micro-organisms, a function that partially depends on their granule content. The complicated regulatory network of neutrophil development and …
View article: MicroRNA‐127‐5p targets the biliverdin reductase B/nuclear factor‐κB pathway to suppress cell growth in hepatocellular carcinoma cells
MicroRNA‐127‐5p targets the biliverdin reductase B/nuclear factor‐κB pathway to suppress cell growth in hepatocellular carcinoma cells Open
Nuclear factor‐κB (NF‐κB) activation is one of the major mediators of inflammation‐induced cancer cell growth and progression. In previous studies, we screened a series of microRNAs (miRNAs) that targeted the NF‐κB signaling pathway. In th…
View article: miR-192, a prognostic indicator, targets the SLC39A6/SNAIL pathway to reduce tumor metastasis in human hepatocellular carcinoma
miR-192, a prognostic indicator, targets the SLC39A6/SNAIL pathway to reduce tumor metastasis in human hepatocellular carcinoma Open
Metastasis is one of the causes of cancer death. Functions and mechanisms of microRNAs (miRNAs) involved in hepatocellular carcinoma (HCC) metastasis are largely unknown. Here, a miRNA microarray analysis was performed in MHCC-97L, MHCC-97…