Explanipedia

Association between cardiac biomarkers and LVEF after congenital heart disease surgery in infants Open

Yingying Mo, Qing Feng, Shuwen Feng, Ming‐Hui Zou, Jinping Liu , et al. · 2025

Objective Cardiac biomarkers are widely used to evaluate postoperative myocardial injury, but studies on their relationship with cardiac function in pediatrics are limited. This study aimed to characterize the dynamic changes of cardiac bi…

Macrophage Notch1 Participates in LPS-Induced Acute Lung Injury via Regulating CCR5 Expression in Mice Open

Ruiyu Zhang, Hui Du, Zhi Liu, Yuxi Lei, Huizhi Hu , et al. · 2025

Background: As pivotal immunoregulatory sentinels in pulmonary defense systems, alveolar macrophages (AMs) play dual roles in mediating inflammatory responses and tissue repair processes during various phases of inflammatory cascades. The …

The growth diversity of preterm infants at 0–36 months corrected age in China: a real-world observational study Open

X. Wang, Shuwen Feng, Pu Yang, Yuxin Wang, Wei Chen , et al. · 2025

Background Premature delivery interrupts the natural growth of the fetus. The postnatal healthy management of preterm infants still follows term standards after a postmenstrual age (PMA) of 40 weeks and there is a lack of research on the l…

Predominance of A2063G mutant strains in the Mycoplasma pneumoniae epidemic in children: A clinical and epidemiological study in 2023 in Wuhan, China Open

Dekyi, Yujia Xiao, Xia Wang, Shuwen Feng, Yuxin Wang , et al. · 2024

A2063G mutant strain MP was the primary pathogen of mycoplasma pneumoniae in children recently, which was often complicated by extra-pulmonary symptoms and complications.

Primary amebic meningoencephalitis in children: A case report and literature review Open

Binbin Song, Junwen Zheng, Dongchi Zhao · 2024

Clinical classification of far lateral lumbar disc herniation under 3D-DESS imaging technology: guidance for PTED operation Open

Junwen Zheng, Wei Liu, Qing Zhu, Guangsheng Li, Gang Wu , et al. · 2023

Backgroud:Many far lateral lumbar disc herniation (FLLDH) classifications utilize image technology to describe the size, shape, and location of disc herniation. However, these approaches are fail in illustrating the spatial relationship be…

BIM-GPT: a Prompt-Based Virtual Assistant Framework for BIM Information Retrieval Open

Junwen Zheng, Martin Fischer · 2023

Efficient information retrieval (IR) from building information models (BIMs) poses significant challenges due to the necessity for deep BIM knowledge or extensive engineering efforts for automation. We introduce BIM-GPT, a prompt-based vir…

Alveolar macrophages and airway hyperresponsiveness associated with respiratory syncytial virus infection Open

Yüxin Wang, Junwen Zheng, Xia Wang, Yang Pu, Dongchi Zhao · 2022

Respiratory syncytial virus (RSV) is a ubiquitous pathogen of viral bronchiolitis and pneumonia in children younger than 2 years of age, which is closely associated with recurrent wheezing and airway hyperresponsiveness (AHR). Alveolar mac…

Comparison of short-term efficacy of MIS-TLIF and Endo-LIF in the treatment of single-segment degenerative lumbar diseases Open

Zhiwei Song, Wei-Hua Zhu, Junwen Zheng, Gang Wu, Tianqi Li , et al. · 2022

Background A prospective controlled study was conducted to compare the short-term clinical results and postoperative complications of minimally invasive transforaminal lumbar decompression and fusion (minimally invasive surgery transforami…

The effect of niobium doping on the corrosion resistance of stainless steel coatings Open

Zhongjie Wang, Junwen Zheng, Xin Zhang · 2022

Human Parvovirus B19 Nonstructural Protein 1 Regulates GATA1 Expression via the Notch Signaling Pathway in K562 Cell Line Open

Dongxin Zeng, Junwen Zheng, Shuwen Feng, Panpan Fan, Dongchi Zhao · 2022

Background: Human parvovirus B19 (B19) infection can affect the hematopoietic arrest in fetus by hindering the differentiation and maturation of erythroid progenitor cells. B19 nonstructural protein 1 (NS1) has been shown to inhibit the di…

Diagnostic values of 2 different techniques for controversial lumbar disc herniation by conventional imaging examination: 3D-DESS vs. CT plain scan Open

Wei Liu, Jinhua Chen, Yanan Zhang, Xu Wang, Junwen Zheng , et al. · 2022

Background: The aim of this study was to explore the significance of three-dimensional double-echo steady-state (3D-DESS) sequence and multidetector computed tomography (CT) plain scan in the diagnosis of lumbar disc herniation (LDH) remai…

Respiratory Syncytial Virus Nonstructural Protein 1 Promotes 5-Lipoxygenase via miR-19a-3p Open

Mei Zheng, Panpan Fan, Pu Yang, Junwen Zheng, Dongchi Zhao · 2022

Background. Respiratory syncytial virus (RSV) infection can regulate the expression of a wide range of noncoding microRNAs (miRNAs), in which mir-19a-3p can participate in airway inflammatory response by regulating 5-lipoxygenase (5-LO) pa…

Dynamic changes of acquired maternal SARS-CoV-2 IgG in infants Open

Xia Wang, Pu Yang, Junwen Zheng, Liu Pin, Wei Cong , et al. · 2021

Maternal SARS-CoV-2 IgG provides limited protection for their infants Open

Xia Wang, Pu Yang, Junwen Zheng, Liu Pin, Wei Cong , et al. · 2020

At present, there are still many ambiguous reports about the perinatal infection of infants born to mothers infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 1-3 . The dynamic characteristics of infantile serum ant…

Mothers infected with SARS-CoV-2 reveals a mild impact on newborns Open

Pu Yang, Junwen Zheng, Liu Pin, Xia Wang, Dongchi Zhao · 2020

Could pregnant women infected with COVID-19 cause adverse consequences for their newborns? 2. Mothers infected with COVID-19 did not cause serious adverse reactions during term labor, but premature infants were prone to gastrointestinal co…

The immunologic status of newborns born to SARS-CoV-2–infected mothers in Wuhan, China Open

Liu Pin, Junwen Zheng, Pu Yang, Xia Wang, Wei Cong , et al. · 2020

Clinical characteristics and risk assessment of newborns born to mothers with COVID-19 Open

Pu Yang, Xia Wang, Liu Pin, Wei Cong, Bingyan He , et al. · 2020

New Insights of Human Parvovirus B19 in Modulating Erythroid Progenitor Cells Differentiation Open

Shuwen Feng, Dongxin Zeng, Junwen Zheng, Zhao Dongchi · 2019

Background Human parvovirus B19, a human pathogen of the erythroparvovirus genus, is responsible for a variety of diseases. Despite less symptoms caused by B19 infection in healthy individuals, this pathogen can not be neglected in specifi…

Phototherapy is associated with the decrease in serum globulin levels in neonatal hyperbilirubinemia Open

Junwen Zheng, Wei Cong, Meng Zhao, Dongchi Zhao · 2018

Previous studies have indicated that phototherapy may be associated with childhood immune disorders in later life. The present study aimed to assess the effects of phototherapy as a risk factor in the decrease in serum globulin (GLB) level…

MicroRNAs: Mediators and Therapeutic Targets to Airway Hyper Reactivity After Respiratory Syncytial Virus Infection Open

Shuwen Feng, Dongxin Zeng, Junwen Zheng, Dongchi Zhao · 2018

Respiratory syncytial virus (RSV) is the most important pathogen correlated to the first-time infant wheezing and later recurrence after its primary infection. RSV infection promotes the bronchial smooth muscle sensitivity to leukotrienes …

Assessment of neonatal brain volume and growth at different postmenstrual ages by conventional MRI Open

Shouyi Wang, Panpan Fan, Dezhi Xiong, Pu Yang, Junwen Zheng , et al. · 2018

Data regarding neonatal brain volumes represent a basis for monitoring early brain development, and large sample of neonatal brain volume data has not been well described. This study was focused on neonatal brain volumes at different postm…

High-dose of intravenous immunoglobulin modulates immune tolerance in premature infants Open

Liu Pin, Lijun Li, Panpan Fan, Junwen Zheng, Dongchi Zhao · 2018

Peripheral blood microRNAs expression is associated with infant respiratory syncytial virus infection Open

Shouyi Wang, Liu Pin, Pu Yang, Junwen Zheng, Dongchi Zhao · 2017

MicroRNAs respond to the inflammatory responses induced by RNA virus infection. In this study, we investigated the specific microRNA profile in the peripheral blood of infants infected with respiratory syncytial virus (RSV). Blood specimen…

A respiratory syncytial virus persistent-infected cell line system reveals the involvement of SOCS1 in the innate antiviral response Open

Junwen Zheng, Pu Yang, Yan Tang, Dongchi Zhao · 2015

Respiratory Syncytial Virus Nonstructural Proteins Upregulate SOCS1 and SOCS3 in the Different Manner from Endogenous IFN Signaling Open

Junwen Zheng, Pu Yang, Yan Tang, Zishu Pan, Dongchi Zhao · 2015

Respiratory syncytial virus (RSV) infection upregulates genes of the suppressor of cytokine signaling (SOCS) family, which utilize a feedback loop to inhibit type I interferon dependent antiviral signaling pathway. Here, we reconstituted R…

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