Jianchao Li
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View article: Unconventional electrochromism in boron arsenide crystal induced by charge symmetry enhancement
Unconventional electrochromism in boron arsenide crystal induced by charge symmetry enhancement Open
View article: Global, regional, and national burdens of lower extremity peripheral arterial disease from 1990 to 2021 and projections to 2050: global burden of disease study 2021
Global, regional, and national burdens of lower extremity peripheral arterial disease from 1990 to 2021 and projections to 2050: global burden of disease study 2021 Open
Background The global and regional burden of lower extremity peripheral artery disease (LEPAD) and its trends have not been systematically studied. Utilizing data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2…
View article: Transplantation with Nonstandard Donor Hearts: Single Center Experience in Central China
Transplantation with Nonstandard Donor Hearts: Single Center Experience in Central China Open
There were no statistically significant differences in the postoperative length of hospitalization, ICU stay, left ventricular ejection fraction, or serum biochemical indicators between the 2 groups. Five patients died during the 3-month f…
View article: Prognostic analysis of children with tetralogy of Fallot through a small incision in the right axilla
Prognostic analysis of children with tetralogy of Fallot through a small incision in the right axilla Open
Objective Compare the clinical efficacy of a minimally invasive small incision in the right axilla vs. traditional median sternotomy in the surgical treatment of tetralogy of Fallot (TOF). Methods A retrospective analysis was conducted on …
View article: Dimerization of the BAR domain–containing protein FAM92A modulates lipid binding and interaction with CBY1
Dimerization of the BAR domain–containing protein FAM92A modulates lipid binding and interaction with CBY1 Open
BAR (Bin/Amphiphysin/Rvs) domain proteins drive membrane remodeling critical for cellular processes like ciliogenesis and organelle morphology. FAM92A (family with sequence similarity 92A), a classical BAR protein, regulates ciliary assemb…
View article: To Explore the Real World Research Status of Traditional Chinese and Western Medicine in the Treatment of Dry Eye Disease
To Explore the Real World Research Status of Traditional Chinese and Western Medicine in the Treatment of Dry Eye Disease Open
Dry eye disease (DED) is a chronic ocular surface disease caused by abnormal tear quality, quantity and dynamics, which can lead to tear film instability, ocular surface microenvironment imbalance, accompanied by inflammation, tissue damag…
View article: Clinical Observation on the Treatment of Central Serous Chorioretinopathy of Liver Depression and Spleen Deficiency Type by TCM Comprehensive Therapy
Clinical Observation on the Treatment of Central Serous Chorioretinopathy of Liver Depression and Spleen Deficiency Type by TCM Comprehensive Therapy Open
Purpose: Clinical effect of traditional Chinese medicine (TCM) comprehensive therapy on 40 cases (80 eyes) of Central Serous Chorioretinopathy (CSC) of Liver Depression and Spleen Deficiency Type was reviewed. Methods: The patients were tr…
View article: Structural insights into the dual Ca2+-sensor-mediated activation of the PPEF phosphatase family
Structural insights into the dual Ca2+-sensor-mediated activation of the PPEF phosphatase family Open
Serine/threonine-protein phosphatases with EF-hands (PPEFs) are a family of highly conserved proteins implicated in cancer and neuronal degeneration. The initially characterized member, Drosophila melanogaster retinal degeneration C (RDGC)…
View article: Effectiveness, safety and adherence of home-based exercise rehabilitation in patients with coronary heart disease patients: A systematic review
Effectiveness, safety and adherence of home-based exercise rehabilitation in patients with coronary heart disease patients: A systematic review Open
View article: Correction: Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation
Correction: Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation Open
View article: Analysis of the characteristics and illness comprehension bias among Chinese patients with psycho-cardiovascular disease: a multi-centre cross-sectional survey
Analysis of the characteristics and illness comprehension bias among Chinese patients with psycho-cardiovascular disease: a multi-centre cross-sectional survey Open
More than 90% of PCD patients in Chinese CVD departments experience mild to moderate anxiety and depression with low treatment rates. Different illness comprehension levels are associated with variations in treatment willingness, considera…
View article: Zebrafish modeling of atypical PML-RARA isoform from acute promyelocytic leukemia patient and its implications for clinical treatment
Zebrafish modeling of atypical PML-RARA isoform from acute promyelocytic leukemia patient and its implications for clinical treatment Open
Acute promyelocytic leukemia (APL) is driven by the specific fusion gene PML-RARA produced by chromosomal translocation. Three classic isoforms, L, V, and S, are found in more than 95% of APL patients. However, atypical PML-RARA isoforms a…
View article: Combined meibomian gland massage and acupuncture enhances tear film and ocular surface health in meibomian gland dysfunction
Combined meibomian gland massage and acupuncture enhances tear film and ocular surface health in meibomian gland dysfunction Open
Meibomian gland massage combined with pressing acupuncture provides significantly greater improvements in tear film stability, glandular function, and ocular surface health compared with massage alone, without increasing adverse reactions.
View article: Unraveling the Potential Mechanisms of Bupleuri Radix-Scutellariae Radix Herb Pair on Non-Alcoholic Fatty Liver Disease by Integrated Transcriptomics, Metabolomics, and Network Pharmacology
Unraveling the Potential Mechanisms of Bupleuri Radix-Scutellariae Radix Herb Pair on Non-Alcoholic Fatty Liver Disease by Integrated Transcriptomics, Metabolomics, and Network Pharmacology Open
View article: The First Principle Guidance Design of Ce-Containing Marine Platform Steel: Dual Regulation of Inclusion Morphology and Corrosion Effect
The First Principle Guidance Design of Ce-Containing Marine Platform Steel: Dual Regulation of Inclusion Morphology and Corrosion Effect Open
View article: Overview of the recent experimental research on the J-TEXT tokamak
Overview of the recent experimental research on the J-TEXT tokamak Open
The J-TEXT capability is enhanced compared to two years ago with several upgrades of its diagnostics and the increase of electron cyclotron resonance heating (ECRH) power to 1 MW. With the application of electron cyclotron wave (ECW), the …
View article: Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition
Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition Open
Activation of hepatic stellate cells (HSCs) is critical in the progression of liver fibrosis and is a promising target for anti-hepatic fibrosis drug development. Moreover, effective pharmacological interventions targeting this pathomechan…
View article: RAD54B promotes gastric cancer cell migration and angiogenesis via the Wnt/β-catenin pathway
RAD54B promotes gastric cancer cell migration and angiogenesis via the Wnt/β-catenin pathway Open
Background Gastric cancer is an epidemic malignancy that is commonly diagnosed at the late stage. Evidence has elucidated that RAD54B exerts a crucial role in the progress of various tumors, but its specific role and mechanism in gastric c…
View article: Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation
Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation Open
View article: Unraveling the Potential Mechanisms of Bupleuri Radix-Scutellariae Radix Herb Pair On Non-Alcoholic Fatty Liver Disease by Integrated Transcriptomics, Metabolomics and Network Pharmacology
Unraveling the Potential Mechanisms of Bupleuri Radix-Scutellariae Radix Herb Pair On Non-Alcoholic Fatty Liver Disease by Integrated Transcriptomics, Metabolomics and Network Pharmacology Open
View article: Highly Precise Strategy of Polygalacturonic Acid Microcarriers Functionalized with Zwitterions and Specific Peptides for Mscs Screening
Highly Precise Strategy of Polygalacturonic Acid Microcarriers Functionalized with Zwitterions and Specific Peptides for Mscs Screening Open
View article: Global, Regional, and National Burden of Lower Extremity Peripheral Arterial Disease 1990-2021 and Projections to 2050: 2021 Global Burden of Disease Study 2021
Global, Regional, and National Burden of Lower Extremity Peripheral Arterial Disease 1990-2021 and Projections to 2050: 2021 Global Burden of Disease Study 2021 Open
View article: Shouhui Tongbian Capsule Ameliorates Obesity by Enhancing Energy Expenditure in Brown Adipose Tissue and Promoting Lipolysis in White Adipose Tissue Via the Camp-Pka Pathway
Shouhui Tongbian Capsule Ameliorates Obesity by Enhancing Energy Expenditure in Brown Adipose Tissue and Promoting Lipolysis in White Adipose Tissue Via the Camp-Pka Pathway Open
View article: Extraction of n = 0 pick-up by locked mode detectors based on neural networks in J-TEXT
Extraction of n = 0 pick-up by locked mode detectors based on neural networks in J-TEXT Open
Measurement of locked mode (LM) is important for the physical research of Magnetohydrodynamic (MHD) instabilities and plasma disruption. The n = 0 pick-up need to be extracted and subtracted to calculate the amplitude and phase of the LM. …
View article: Shouhui Tongbian Capsule in treatment of constipation: Treatment and mechanism development
Shouhui Tongbian Capsule in treatment of constipation: Treatment and mechanism development Open
Constipation is common in the diseases of the digestive system in clinics. With the change in diet structure and the increase in life pressure, the prevalence rate increases year by year. In traditional Chinese medicine (TCM), the location…
View article: Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance
Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance Open
View article: Sclerotome-derived PDGF signaling functions as a niche cue responsible for primitive erythropoiesis
Sclerotome-derived PDGF signaling functions as a niche cue responsible for primitive erythropoiesis Open
Primitive erythropoiesis serves a vital role in embryonic development, generating primitive red blood cells responsible for transportation of oxygen throughout the body. Although diverse niche factors are known to function in definitive he…
View article: Recent Progress in Extracellular Vesicle-Based Carriers for Targeted Drug Delivery in Cancer Therapy
Recent Progress in Extracellular Vesicle-Based Carriers for Targeted Drug Delivery in Cancer Therapy Open
Extracellular vesicles (EVs) are small, membrane-based vesicles released by cells that play a critical role in various physiological and pathological processes. They act as vehicles for transporting a variety of endogenous cargo molecules,…
View article: Availability and trend of dissemination of cardiac rehabilitation in China: report from the multicenter national registration platform between 2012 and 2021
Availability and trend of dissemination of cardiac rehabilitation in China: report from the multicenter national registration platform between 2012 and 2021 Open
The study aimed to evaluate the current status of cardiac rehabilitation programs in China by registering and tracking patients undergoing CR programs in the database. Data were extracted from the online registry platform of the China Soci…
View article: Investigation of the J-TEXT plasma events by k-means clustering algorithm
Investigation of the J-TEXT plasma events by k-means clustering algorithm Open
Various types of plasma events emerge in specific parameter ranges and exhibit similar characteristics in diagnostic signals, which can be applied to identify these events. A semi-supervised machine learning algorithm, the k -means cluster…