Explanipedia

TJ0113-induced mitophagy in acute liver failure detected by Raman microspectroscopy Open

Chunlian Huang, Jiaqi Liao, Xufeng Cen, Changwei Jiao, Si‐Jia Chen , et al. · 2025

Design of a Highly Active Peptide Inhibitor of Farnesyltransferase and Its Protective Effect Against Acute Liver Failure Open

Chun-Lian Huang, Hui Qu, Anne Li, Chen-Qian Ying, Hui Shao , et al. · 2025

Collectively, these findings demonstrate that PD081376(d2,d3,d5) could alleviate LPS/D-GaIN or TAA-induced ALF by regulating apoptosis, pyroptosis, and necrotizing apoptosis, which might provide a new therapeutic strategy and scalability c…

Hesitation towards COVID-19 booster vaccination among dialysis patients: a cross-sectional study in Taizhou, China Open

Chengwen Luo, Tao‐Hsin Tung, Jiansheng Zhu · 2024

Positive and negative factors of parents vaccinating their children against COVID-19: An umbrella review Open

Hui Wu, Chun-Lian Huang, Jing-Shan Deng, Chen-Qian Ying, Tao‐Hsin Tung , et al. · 2024

Impact of prior SARS-CoV-2 infection on college students’ hesitancy to receive additional COVID-19 vaccine booster doses: A study from Taizhou, China Open

Jing-Shan Deng, Chun-Lian Huang, Hu Q, Lei Shi, Chen Xiao-ying , et al. · 2024

A history of SARS-CoV-2 infection affects college students' hesitation to receive additional COVID-19 vaccine booster doses, which was higher in those who experienced secondary infections.

Temporal Trends in Prevalence Of Chronic Liver Disease Among Women of Childbearing Age from 1992 to 2021: An Age-Period-Cohort Analysis Open

Hedan Chen, Hongwei Wu, Jiansheng Zhu, Junyan Liu, Ali Li , et al. · 2024

Impact of household decision makers’ hesitancy to vaccinate children against COVID-19 on other household members: A family-based study in Taizhou, China Open

Jing-Shan Deng, Chen-Qian Ying, Xiaoqing Lin, Chun-Lian Huang, Meixian Zhang , et al. · 2023

The present study found that family decision makers' hesitation to vaccinate children against COVID-19 influenced other family members' hesitation to vaccinate children. In addition, family decision makers' perceptions of the safety of the…

Application of non-invasive prenatal testing to 91,280 spontaneous pregnancies and 3477 pregnancies conceived by in vitro fertilization Open

Rong Wei, Jingran Li, Yuanyuan Xia, Chao-hong Wang, Xinran Lu , et al. · 2023

Attitudes of vaccination workers toward COVID-19 vaccination in patients with chronic liver disease Open

Yongzhi Tang, Chun-Lian Huang, Xiao-Qing Ling, Xiao-Hong Ye, Guang-Ming Xu , et al. · 2023

Objectives Vaccination workers play an important role in the acceptance of various vaccines in patients with chronic liver diseases. We mainly investigated the attitude of vaccination workers toward COVID-19 vaccination in patients with ch…

Influencing factors of COVID-19 vaccination hesitancy among adults in Taiwan, China: a cross-sectional study Open

Chun-Lian Huang, Jau‐Yuan Chen, Xiaoying Chen, Xiaoqing Lin, Jing-Shan Deng , et al. · 2023

Objectives The promotion of the COVID-19 vaccine is key to controlling the spread of COVID-19. One of the most significant obstacles in tackling the pandemic is vaccine hesitancy. While many published studies have examined vaccine hesitanc…

Clinical application value of expanded carrier screening in the population of childbearing age Open

Yuqin Fang, Jingran Li, Miaomiao Zhang, Yuan Cheng, Chao-hong Wang , et al. · 2023

Objective The objective of this study was to explore the clinical utility of the implementation of expanded carrier screening (ECS) in Chinese population of childbearing age. Materials and methods Based on capillary electrophoresis, a firs…

Applications of non-invasive prenatal testing in 91280 spontaneous pregnancies and 3477 pregnant women undergoing in vitro Fertilization Open

Rong Wei, Jingran Li, Xinran Lu, Miaomiao Zhang, Yuqin Fang , et al. · 2023

Background A large number of clinical studies based on spontaneous pregnancies (SP) have proved the superiority of non-invasive prenatal testing (NIPT), and whether this technology is suitable for the offspring of assisted reproductive tec…

Parental hesitancy against COVID-19 vaccination for children and associated factors in Taiwan Open

Jing-Shan Deng, Jau‐Yuan Chen, Xiaoqing Lin, Chun-Lian Huang, Tao‐Hsin Tung , et al. · 2023

Value of noninvasive prenatal testing in the detection of rare fetal autosomal abnormalities Open

Miaomiao Zhang, Junxiang Tang, Jingran Li, Chao-hong Wang, Rong Wei , et al. · 2023

NIPT is not recommended for screening for RATs. However, considering that positive results are associated with an increased risk of IUGR and PTB, additional fetal ultrasound examination should be performed to monitor fetal growth. In addit…

Relationship between COVID-19 vaccine hesitancy and willingness to pay for the booster dose of COVID-19 vaccine of oncology patients in Taizhou, China Open

Jia‐Xiang An, Xiaoqing Lin, Bojian Xie, Tao‐Hsin Tung, Jiansheng Zhu · 2023

Hesitant patients with cancer had a lower WTP for the booster dose against COVID-19 than non-hesitant participants. These results imply that further health education programmes are essential to decrease the hesitancy of patients with cance…

Proteomics Investigation of Diverse Serological Patterns in COVID-19 Open

Xiao Liang, Rui Sun, Jing Wang, Kai Zhou, Jun Li , et al. · 2023

Willingness of college students to receive COVID-19 heterologous vaccination in Taizhou, China Open

Hui Shao, Xiaoqing Lin, Yan Chen, Li Lv, Chen-Qian Ying , et al. · 2023

This study aimed to determine the willingness of college students to choose COVID-19 heterologous vaccination and its associated influencing factors in Taizhou, China. A population-based, self-administered online questionnaire was conducte…

Parents’ willingness to pay for their children’s COVID-19 vaccine in Taiwan, China: A cross-sectional study Open

Chun-Lian Huang, Jau‐Yuan Chen, Xiaoqing Lin, Jing-Shan Deng, Tao‐Hsin Tung , et al. · 2023

Most COVID-19 studies aim to assess factors influencing willingness to pay for vaccines between the public and medical staff. However, few studies focus on parents' willingness to pay for their children's COVID-19 vaccine. The current stud…

IgG response to spike protein of SARS-CoV-2 in healthy individuals and potential of intravenous IgG as treatment for COVID-19 Open

Gang Wang, Zebao He, Fengtian Wu, Zhengming Ge, Jiansheng Zhu , et al. · 2022

Background The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19), which is currently a worldwide pandemic. There are limited available treatments for severe COVID-19 patients. …

Adverse reactions to inactivated COVID-19 vaccination in patients with chronic liver disease: The effect of anxiety Open

Li Lv, Xiaoqing Lin, Yan Chen, He-Dan Chen, Meixian Zhang , et al. · 2022

Studies have shown that patients with chronic liver disease are at a higher risk of contracting novel coronavirus pneumonia than healthy individuals, and many guidelines state that patients with chronic liver disease should be prioritized …

Willingness of Older Adults with Chronic Diseases to Receive a Booster Dose of Inactivated Coronavirus Disease 2019 Vaccine: A Cross-Sectional Study in Taizhou, China Open

Xiaoqing Lin, A-Li Li, Meixian Zhang, Li Lv, Yan Chen , et al. · 2022

Vaccination is an important measure to control the spread of COVID-19 among elderly high-risk groups; however, the propensity to receive COVID-19 vaccine boosters has not been evaluated in these populations. Here, we aimed to investigate t…

Intentions of Patients with Hypertension to Receive a Booster Dose of the COVID-19 Vaccine: A Cross-Sectional Survey in Taizhou, China Open

Chen-Qian Ying, Xiaoqing Lin, Li Lv, Yan Chen, Jianjun Jiang , et al. · 2022

COVID-19 patients with hypertension have increased hospital complications and mortality rates. Moreover, these patients also have lower antibody titers after receiving the coronavirus disease (COVID-19) vaccine. Therefore, patients with hy…

Parents in Taiwan are hesitant to have their children vaccinated against COVID-19 and its influencing factors Open

Jing-Shan Deng, Jau‐Yuan Chen, Xiaoqing Lin, Chun-Lian Huang, Tao‐Hsin Tung , et al. · 2022

Background Since July 2021, some countries and regions have initiated the vaccination of minors against COVID-19, and the parents' COVID-19 vaccine hesitancy will affect the vaccination of minors. The motive of our learning was to be to di…

COVID-19 booster vaccine willingness among patients with chronic kidney disease in Taizhou, China Open

He-Dan Chen, Guang-Biao Xu, Yan Chen, Xiaoqing Lin, Li Lv , et al. · 2022

Purpose Investgate the willingness of CKD patients to receive a COVID-19 booster vaccine dose and analyze the related factors of COVID-19 booster vaccine willingness in such patients. Methods An online questionnaire investigation addressin…

The main decision-making competence for willingness-to-pay towards COVID-19 vaccination: a family-based study in Taizhou, China Open

Chengwen Luo, Meixian Zhang, Eva Jiang, Mindan Jin, Tao‐Hsin Tung , et al. · 2022

This study found that family decision-makers were more willing to pay for both the first two doses and the booster dose of COVID-19 vaccines in Taizhou, China. To improve the WTP for COVID-19 vaccines, public policy programs need to conduc…

Relationship between knowledge, attitudes, and practices and COVID-19 vaccine hesitancy: A cross-sectional study in Taizhou, China Open

Xiaoqing Lin, Meixian Zhang, Yan Chen, Ji-Ji Xue, He-Dan Chen , et al. · 2022

Objective This study aimed to explore COVID-19 vaccine hesitancy in Chinese adults and analyzed the relationship between knowledge, attitudes, practices (KAP), and COVID-19 vaccine hesitancy. Methods A population-based self-administered on…

Proteomics Investigation of Diverse Serological Patterns in COVID-19 Open

Xiao Liang, Rui Sun, Jing Wang, Kai Zhou, Jun Li , et al. · 2022

Serum antibodies IgM and IgG are elevated during COVID-19 to defend against viral attack. Atypical results such as negative and abnormally high antibody expression were frequently observed whereas the underlying molecular mechanisms are el…

Willingness-to-pay for a booster dose of inactivated SARS-CoV-2 vaccine in Taizhou, China Open

Tao‐Hsin Tung, Xiaoqing Lin, Yan Chen, Meixian Zhang, Jiansheng Zhu · 2022

This study was conducted to ascertain whether people in China would be willing to pay for an inactivated COVID-19 vaccine booster dose. An online survey estimating participants' willingness to pay (WTP) for a booster dose of COVID-19 vacci…

COVID-19 booster vaccine willingness among patients with chronic kidney disease in Taizhou, China Open

He-Dan Chen, Guang-Biao Xu, Yan Chen, Xiaoqing Lin, Li Lv , et al. · 2022

Purpose: Investgate the willingness of CKD patients to receive a COVID-19 booster vaccine dose and analyze the related factors of COVID-19 booster vaccine willingness in such patients. Methods: An online questionnaire investigation address…

COVID-19 vaccine hesitancy between teachers and students in a college, a cross-sectional study in China Open

Yan Chen, Meixian Zhang, Xiaoqing Lin, Hongwei Wu, Tao‐Hsin Tung , et al. · 2022

Studies have identified teacher effects on students' attitudes. This study explored the differences in and associations between teachers' and students' COVID-19 vaccine hesitancy, and the factors that affect it. A population-based self-adm…

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