Junxiang Peng
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View article: Anlotinib may have a therapeutic effect on papillary craniopharyngiomas without the BRAFv600e mutation
Anlotinib may have a therapeutic effect on papillary craniopharyngiomas without the BRAFv600e mutation Open
BRAFv600e- PCPs are characterized by calcification and do not respond to the BRAF inhibitor vemurafenib, and for which the angiogenesis inhibitor anlotinib may have a significant therapeutic effect.
View article: Spatiotemporal composition and diversity of endophyte communities in Dracaena cambodiana on Hainan Island
Spatiotemporal composition and diversity of endophyte communities in Dracaena cambodiana on Hainan Island Open
Introduction Dracaena cambodiana produces a red resin known as Dragon’s blood, which is used worldwide in traditional medicine and as a dye. The role of endophytes in the resin-formation process remains underexplored. Understanding the end…
View article: Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in subarachnoid hemorrhage
Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in subarachnoid hemorrhage Open
View article: Distinction of papillary and adamantinomatous craniopharyngioma: Clinical features, surgical nuances and hypothalamic outcomes
Distinction of papillary and adamantinomatous craniopharyngioma: Clinical features, surgical nuances and hypothalamic outcomes Open
View article: Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in aneurysmal subarachnoid hemorrhage
Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in aneurysmal subarachnoid hemorrhage Open
The incidence of growth hormone deficiency (GHD) after aneurysmal subarachnoid hemorrhage (aSAH) is significantly higher than that of other neuroendocrine disorders, but the mechanism is still elusive. We used mass spectrometry to identify…
View article: Estimation of botanical composition of forage crops using laboratory-based hyperspectral imaging and near-infrared spectrometer measurements
Estimation of botanical composition of forage crops using laboratory-based hyperspectral imaging and near-infrared spectrometer measurements Open
Harvested forage is the main raw feed for ruminant animals in Sweden, and is commonly cultivated in mixed stands of legume and grass species. The fraction of legume on a dry matter basis, known as botanical composition (BC) is a very impor…
View article: Head circumferences measured during developmental monitoring visits before diagnosis of childhood-onset craniopharyngioma
Head circumferences measured during developmental monitoring visits before diagnosis of childhood-onset craniopharyngioma Open
Background Craniopharyngiomas (CP) are histologically benign (WHO grade 1), embryonal malformations which are related to remnants of the Rathke’s pouch and are located in the (peri)sellar region. Already before CP diagnosis, many patients …
View article: Reassessing the Reliability of Ki-67 as an Indicator of Pituitary Neuroendocrine Tumor Progression: Based on Cell Lineage Categorization
Reassessing the Reliability of Ki-67 as an Indicator of Pituitary Neuroendocrine Tumor Progression: Based on Cell Lineage Categorization Open
Background: The role of KI-67, a tumor proliferation marker, as a biomarker for progression in pituitary neuroendocrine tumors (PitNETs) remains controversial. The aim of this study was to analyze the relationship between KI-67 expression …
View article: Effect of growth hormone on cell proliferation and biological behavior of adamantinomatous craniopharyngioma cells
Effect of growth hormone on cell proliferation and biological behavior of adamantinomatous craniopharyngioma cells Open
Purpose: This study aims to investigate the impact of growth hormone therapy on the postoperative management of craniopharyngioma and to evaluate the direct influence of GH on craniopharyngioma. Methods: The research involved the applicati…
View article: Editorial: Recent advances in pediatric craniopharyngioma
Editorial: Recent advances in pediatric craniopharyngioma Open
Citation: Müller HL, Zhou J and Peng J (2024) Editorial: Recent advances in pediatric craniopharyngioma. Front. Endocrinol. 15:1413744. doi: 10.3389/fendo.2024.1413744
View article: Screening and validation of reference genes in Dracaena cochinchinensis using quantitative real-time PCR
Screening and validation of reference genes in Dracaena cochinchinensis using quantitative real-time PCR Open
Dragon's blood, the red resin derived from the wounded Dracaena , is a precious traditional medicine used by different culture. Dracaena cochinchinensis is one of the main species of Dracaena , and is the endangered medicinal plants in Chi…
View article: Factor analysis and subtyping significance of CTNNB1 gene mutation detection in adamantinomatous craniopharyngioma
Factor analysis and subtyping significance of CTNNB1 gene mutation detection in adamantinomatous craniopharyngioma Open
View article: Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system
Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system Open
JOURNAL/nrgr/04.03/01300535-202410000-00026/figure1/v/2025-03-16T123217Z/r/image-tiff Previous studies have shown that growth hormone can regulate hypothalamic energy metabolism, stress, and hormone release. Therefore, growth hormone has g…
View article: THU221 Measurements Of Head Circumference During Developmental Monitoring Visits Before Diagnosis Of Pediatric Craniopharyngioma
THU221 Measurements Of Head Circumference During Developmental Monitoring Visits Before Diagnosis Of Pediatric Craniopharyngioma Open
Disclosure: J. Beckhaus: None. S. Boekhoff: None. L. Krieger: None. J. Peng: None. C. Friedrich: None. H.L. Muller: None. Craniopharyngiomas (CP) are congenital, benign, embryonic malformations which arise from ectoblastic remnants of Rath…
View article: Forage Biomass Estimation Using Sentinel-2 Imagery at High Latitudes
Forage Biomass Estimation Using Sentinel-2 Imagery at High Latitudes Open
Forages are the most important kind of crops at high latitudes and are the main feeding source for ruminant-based dairy industries. Maximizing the economic and ecological performances of farms and, to some extent, of the meat and dairy sec…
View article: Microglia-Derived Adam9 Regulates Ghrh Neuron Pyroptosis in Aneurysmal Subarachnoid Hemorrhage
Microglia-Derived Adam9 Regulates Ghrh Neuron Pyroptosis in Aneurysmal Subarachnoid Hemorrhage Open
View article: Inhibition of integrated stress response protects against lipid-induced senescence in hypothalamic neural stem cells in adamantinomatous craniopharyngioma
Inhibition of integrated stress response protects against lipid-induced senescence in hypothalamic neural stem cells in adamantinomatous craniopharyngioma Open
Background Adamantinomatous craniopharyngioma (ACP) is a benign tumor with malignant clinical manifestations. ACP adjacent to the hypothalamus often presents with more severe symptoms and higher incidence of hypothalamic dysfunction. Howev…
View article: Estimation of Dry Matter and N Nutrient Status of Choy Sum by Analyzing Canopy Images and Plant Height Information
Estimation of Dry Matter and N Nutrient Status of Choy Sum by Analyzing Canopy Images and Plant Height Information Open
The estimation accuracy of plant dry matter by spectra- or remote sensing-based methods tends to decline when canopy coverage approaches closure; this is known as the saturation problem. This study aimed to enhance the estimation accuracy …
View article: Adamantinomatous craniopharyngioma cyst fluid can trigger inflammatory activation of microglia to damage the hypothalamic neurons by inducing the production of β-amyloid
Adamantinomatous craniopharyngioma cyst fluid can trigger inflammatory activation of microglia to damage the hypothalamic neurons by inducing the production of β-amyloid Open
Introduction The mechanism by which adamantinomatous craniopharyngioma (ACP) damages the hypothalamus is still unclear. Cyst fluid rich in lipids and inflammatory factors is a characteristic pathological manifestation of ACP and may play a…
View article: Adamantinomatous Craniopharyngioma Cyst Fluid can Trigger Inflammatory Activation of Microglia to Damage the Hypothalamic Neurons by Inducing the Production of β-Amyloid
Adamantinomatous Craniopharyngioma Cyst Fluid can Trigger Inflammatory Activation of Microglia to Damage the Hypothalamic Neurons by Inducing the Production of β-Amyloid Open
Introduction: The mechanism by which adamantinomatous craniopharyngioma (ACP) damages the hypothalamus is still unclear. Cyst fluid rich in lipids and inflammatory factors is a characteristic pathological manifestation of ACP and may play …
View article: Nuchal Skinfold Thickness in Pediatric Brain Tumor Patients
Nuchal Skinfold Thickness in Pediatric Brain Tumor Patients Open
Background Severe obesity and tumor relapse/progression have impact on long-term prognosis in pediatric brain tumor patients. Methods In a cross-sectional study, we analyzed nuchal skinfold thickness (NST) on magnetic-resonance imaging (MR…
View article: Reinvestigating Tumor–Ventricle Relationship of Craniopharyngiomas With Predominantly Ventricular Involvement: An Endoscopic Endonasal Series Based on Histopathological Assessment
Reinvestigating Tumor–Ventricle Relationship of Craniopharyngiomas With Predominantly Ventricular Involvement: An Endoscopic Endonasal Series Based on Histopathological Assessment Open
Objective Craniopharyngiomas (CPs) predominantly involving the third ventricle were commonly termed “intraventricular” lesions. The aim of this study was to clarify the anatomical relationship between the tumor and the third ventricle by b…
View article: Computational Network Pharmacology–Based Strategy to Capture Key Functional Components and Decode the Mechanism of Chai-Hu-Shu-Gan-San in Treating Depression
Computational Network Pharmacology–Based Strategy to Capture Key Functional Components and Decode the Mechanism of Chai-Hu-Shu-Gan-San in Treating Depression Open
Traditional Chinese medicine (TCM) usually plays therapeutic roles on complex diseases in the form of formulas. However, the multicomponent and multitarget characteristics of formulas bring great challenges to the mechanism analysis and se…
View article: Body Composition and Nuchal Skinfold Thickness in Pediatric Brain Tumor Patients
Body Composition and Nuchal Skinfold Thickness in Pediatric Brain Tumor Patients Open
Obesity, cardiovascular disease, and relapse/progression have major impact on prognosis in pediatric brain tumor patients. Cranial MRI is part of routine follow-up. In a cross-sectional study, we analyzed nuchal skinfold thickness (NST) by…
View article: Endoscopic endonasal versus transcranial surgery for primary resection of craniopharyngiomas based on a new QST classification system: a comparative series of 315 patients
Endoscopic endonasal versus transcranial surgery for primary resection of craniopharyngiomas based on a new QST classification system: a comparative series of 315 patients Open
OBJECTIVE An assessment of the transcranial approach (TCA) and the endoscopic endonasal approach (EEA) for craniopharyngiomas (CPs) according to tumor types has not been reported. The aim of this study was to evaluate both surgical approac…
View article: System Pharmacology-Based Strategy to Investigate Core Component Group and Molecular Mechanisms of Xuefu Zhuyu Decoction in the Treatment of Gbm
System Pharmacology-Based Strategy to Investigate Core Component Group and Molecular Mechanisms of Xuefu Zhuyu Decoction in the Treatment of Gbm Open
BackgroundXuefu Zhuyu Decoction (XFZYD) is a well-known Traditional Chinese Medicine (TCM) formula that has many pharmacological effects, including enhancing immune function, improving hemorheology and regulating blood vessels bidirectiona…
View article: Analysis of Molecular Mechanism of Erxian Decoction in Treating Osteoporosis Based on Formula Optimization Model
Analysis of Molecular Mechanism of Erxian Decoction in Treating Osteoporosis Based on Formula Optimization Model Open
Osteoporosis (OP) is a highly prevalent orthopedic condition in postmenopausal women and the elderly. Currently, OP treatments mainly include bisphosphonates, receptor activator of nuclear factor kappa‐B ligand (RANKL) antibody therapy, se…
View article: RARE-61. BODY COMPOSITION AND NUCHAL SKINFOLD THICKNESS IN PEDIATRIC BRAIN TUMOR PATIENTS
RARE-61. BODY COMPOSITION AND NUCHAL SKINFOLD THICKNESS IN PEDIATRIC BRAIN TUMOR PATIENTS Open
BACKGROUND Obesity, cardiovascular disease (CVD), and relapse/progression have major impact on prognosis in pediatric brain tumor (BT) patients. Cranial MRI is part of routine follow-up. METHODS In a cross-sectional study, we analyzed nuch…
View article: Establishment of age group classification for risk stratification in glioma patients
Establishment of age group classification for risk stratification in glioma patients Open
View article: Feasibility of primary human cell cultures as a model for adamantinomatous craniopharyngioma research: Evidence from RNA‑Seq analysis
Feasibility of primary human cell cultures as a model for adamantinomatous craniopharyngioma research: Evidence from RNA‑Seq analysis Open
Adamantinomatous craniopharyngioma (ACP) is a benign epithelial tumor of the sellar region. Whether primary human cell cultures can be used as a stable research model has yet to be determined. The characteristics of three cultured cranioph…