Junxing Xian
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View article: Topological signatures of brain dynamics: persistent homology reveals individuality and brain–behavior links
Topological signatures of brain dynamics: persistent homology reveals individuality and brain–behavior links Open
Introduction Understanding individual differences in brain dynamics is a central goal in neuroscience. While conventional time series features capture signal properties of local brain regions, they often fail to reveal the deeper structure…
View article: TransBrain: A computational framework for translating brain-wide phenotypes between humans and mice
TransBrain: A computational framework for translating brain-wide phenotypes between humans and mice Open
Despite remarkable advances in whole-brain imaging technologies, the lack of quantitative approaches to bridge rodent preclinical and human studies remains a critical challenge. Here we present TransBrain, a computational framework enablin…
View article: Longevity or Well-being? A Dual-Dimension Structure of Neuroticism
Longevity or Well-being? A Dual-Dimension Structure of Neuroticism Open
The development of personality traits is often viewed as evolutionarily adaptive. Current neuroticism research, however, predominantly highlights its negative health impacts, neglecting its potential evolutionary advantages. We propose tha…
View article: Probing Individual Differences in the Topological Landscape of Naturalistic Brain Dynamics
Probing Individual Differences in the Topological Landscape of Naturalistic Brain Dynamics Open
Psychiatry seeks to unravel brain dysfunction and individual differences in real-world contexts. Naturalistic stimuli, like movie watching, are increasingly recognized for eliciting complex, context-dependent neural activity with high ecol…
View article: Deciphering complex brain spatiotemporal dynamics shaping diverse human behavior
Deciphering complex brain spatiotemporal dynamics shaping diverse human behavior Open
As a complex dynamic system, the brain remains notably active even at rest. Yet, the behavioral significance of such spontaneous activity is largely uncharted. We hypothesize that the variations in human behavior between individuals are em…