J.-L. Lan
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View article: Dysregulation of the JNK signaling pathway in tuberculosis: mechanisms and therapeutic strategies
Dysregulation of the JNK signaling pathway in tuberculosis: mechanisms and therapeutic strategies Open
Tuberculosis (TB), which is caused by Mycobacterium tuberculosis ( Mtb), remains a major infectious disease worldwide. Despite the availability of anti-TB drugs, the emergence of drug resistance, the need for prolonged treatment duration a…
View article: Association Between Atherogenic Index of Plasma and Clinical Outcomes in Peritoneal Dialysis Population
Association Between Atherogenic Index of Plasma and Clinical Outcomes in Peritoneal Dialysis Population Open
Background: The atherogenic index of plasma (AIP), a prognostic indicator for cardiovascular disease, has not been fully explored in relation to clinical outcomes in patients receiving peritoneal dialysis. This study aims to elucidate the …
View article: Effects of electroacupuncture on neural function and the expression of inflammation-related proteins NLRP3/caspase-1 in rats with ischemic stroke
Effects of electroacupuncture on neural function and the expression of inflammation-related proteins NLRP3/caspase-1 in rats with ischemic stroke Open
This study aimed to investigate the neuroprotective effects of electroacupuncture (EA) at the Baihui and Dazhui acupoints in a rat model of ischemia-reperfusion injury. Ninety-six male Sprague–Dawley rats were randomly assigned to four gro…
View article: The Association Between Atherogenic Index of Plasma and Clinical Outcomes in Peritoneal Dialysis Population
The Association Between Atherogenic Index of Plasma and Clinical Outcomes in Peritoneal Dialysis Population Open
Background The atherogenic index of plasma (AIP), a prognostic indicator for cardiovascular disease, has been underexplored in relation to clinical outcomes in patients receiving peritoneal dialysis. This study aims to elucidate the relati…
View article: Utilizing network pharmacology, pharmacodynamics, molecular biology studies, and molecular docking techniques to uncover the mechanism of the Ligusticum wallichii-borneol medication combination for the treatment of ischemic stroke in rat models
Utilizing network pharmacology, pharmacodynamics, molecular biology studies, and molecular docking techniques to uncover the mechanism of the Ligusticum wallichii-borneol medication combination for the treatment of ischemic stroke in rat models Open
Objective.To use pharmacodynamics, molecular biology studies, network pharmacology, and molecular docking to study the mechanism of action of the Ligusticum wallichii (known as Chuanxiong in China, CX) and borneol (known as Bingpian in Chi…
View article: Preoperative NLR Combined with Ultrasound to Construct a Predictive Model for Central Lymph Node Metastasis in cN0 Papillary Thyroid Carcinoma
Preoperative NLR Combined with Ultrasound to Construct a Predictive Model for Central Lymph Node Metastasis in cN0 Papillary Thyroid Carcinoma Open
Objective This study aims to evaluate the preoperative neutrophil-to-lymphocyte ratio (NLR) and ultrasound tumor characteristics to identify risk factors for central lymph node metastasis (CLNM) in clinically lymph node-negative (cN0) papi…
View article: Chronic hepatitis B virus infection and risk of chronic kidney disease: a population-based prospective cohort study of 0.5 million Chinese adults
Chronic hepatitis B virus infection and risk of chronic kidney disease: a population-based prospective cohort study of 0.5 million Chinese adults Open
Background Existing evidence remains inconclusive as to the association between chronic hepatitis B virus (HBV) infection and the risk of chronic kidney disease (CKD). We prospectively examined the association between chronic HBV infection…