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View article: The Functional Connectome Mediates Associations Between Fitness and Cognition Across the Adult Lifespan
The Functional Connectome Mediates Associations Between Fitness and Cognition Across the Adult Lifespan Open
Cardiorespiratory fitness (CRF) is increasingly recognized as essential for improving neural and cognitive function, especially in older age. Here, we examined a cross‐sectional sample of the Human Connectome Project (HCP) Aging dataset (a…
View article: Sedentary behavior, cognition, and brain health in older adults: a systematic review
Sedentary behavior, cognition, and brain health in older adults: a systematic review Open
Sedentary behavior has been associated with poor health outcomes, especially in older adulthood. Given that sedentary behavior is a highly prevalent, modifiable health behavior, there has been a recent increased interest in examining how s…
View article: Associations of cardiorespiratory fitness with cerebral cortical thickness and gray matter volume across the adult lifespan
Associations of cardiorespiratory fitness with cerebral cortical thickness and gray matter volume across the adult lifespan Open
High cardiorespiratory fitness may mitigate regional gray matter shrinkage across the adult lifespan.
View article: Associations of Central Arterial Stiffness With Brain White Matter Integrity and Gray Matter Volume in <scp>MRI</scp> Across the Adult Lifespan
Associations of Central Arterial Stiffness With Brain White Matter Integrity and Gray Matter Volume in <span>MRI</span> Across the Adult Lifespan Open
Background Central arterial stiffening is associated with brain white matter (WM) damage and gray matter (GM) volume loss in older adults, but little is known about this association from an adult lifespan perspective. Purpose To investigat…
View article: Age and Sex‐Related Differences in Neuroprotective Effects of Cardiovascular Endurance on Cortical Thickness and Brain Volume in Adults Across Age
Age and Sex‐Related Differences in Neuroprotective Effects of Cardiovascular Endurance on Cortical Thickness and Brain Volume in Adults Across Age Open
Background Higher cardiorespiratory fitness and cardiovascular endurance (CE) have been shown to be neuroprotective in older adulthood, but the mechanisms underlying this neuroprotection across the adult lifespan are poorly understood. The…
View article: High Blood Pressure Is Associated With Lower Brain Volume and Cortical Thickness in Healthy Young Adults
High Blood Pressure Is Associated With Lower Brain Volume and Cortical Thickness in Healthy Young Adults Open
BACKGROUND High blood pressure (BP) in middle-aged and older adults is associated with lower brain volume and cortical thickness assessed with structural magnetic resonance imaging (MRI). However, little evidence is available on young adul…
View article: Association of Blood Pressure With Brain White Matter Microstructural Integrity Assessed With MRI Diffusion Tensor Imaging in Healthy Young Adults
Association of Blood Pressure With Brain White Matter Microstructural Integrity Assessed With MRI Diffusion Tensor Imaging in Healthy Young Adults Open
BACKGROUND: High blood pressure (BP) in middle-aged and older adults is associated with a brain white matter (WM) microstructural abnormality. However, little evidence is available in healthy young adults. We investigated the associations …
View article: 5 Large-Scale Network Connectivity and Cognitive Function after Exercise Training in Older Adults
5 Large-Scale Network Connectivity and Cognitive Function after Exercise Training in Older Adults Open
Objective: Despite growing evidence regarding the association between exercise training (ET) and functional brain connectivity, little is known about the effects of ET on within- and between-network functional connectivity (FC) of core bra…
View article: Hippocampal functional connectivity mediates the association between cardiorespiratory fitness and cognitive function in healthy young adults
Hippocampal functional connectivity mediates the association between cardiorespiratory fitness and cognitive function in healthy young adults Open
Objective: Higher cardiorespiratory fitness (CRF) induces neuroprotective effects in the hippocampus, a key brain region for memory and learning. We investigated the association between CRF and functional connectivity (FC) of the hippocamp…
View article: Emotional processing and positive affect after acute exercise in healthy older adults
Emotional processing and positive affect after acute exercise in healthy older adults Open
The well‐elucidated improvement of mood immediately after exercise in older adults presumably involves adaptations in emotion‐processing brain networks. However, little is known about effects of acute exercise on appetitive and aversive em…
View article: Large-Scale Network Connectivity and Cognitive Function Changes After Exercise Training in Older Adults with Intact Cognition and Mild Cognitive Impairment
Large-Scale Network Connectivity and Cognitive Function Changes After Exercise Training in Older Adults with Intact Cognition and Mild Cognitive Impairment Open
Background: Despite growing evidence regarding the association between exercise training (ET) and functional brain network connectivity, little is known about the effects of ET on large-scale within- and between-network functional connecti…
View article: The Effects of Exergaming on Attention in Children With Attention Deficit/Hyperactivity Disorder: Randomized Controlled Trial
The Effects of Exergaming on Attention in Children With Attention Deficit/Hyperactivity Disorder: Randomized Controlled Trial Open
Background Despite growing evidence showing the effects of exercise and cognitive trainings on enhancing attention, little is known about the combined effects of exergame on attention in children with attention deficit/hyperactivity disord…
View article: The Effects of Exergaming on Executive and Physical Functions in Older Adults With Dementia: Randomized Controlled Trial
The Effects of Exergaming on Executive and Physical Functions in Older Adults With Dementia: Randomized Controlled Trial Open
Background Despite increasing interest in the effects of exergaming on cognitive function, little is known about its effects on older adults with dementia. Objective The purpose of this is to investigate the effects of exergaming on execut…
View article: Cardiorespiratory Fitness as a Moderator of Sleep-Related Associations with Hippocampal Volume and Cognition
Cardiorespiratory Fitness as a Moderator of Sleep-Related Associations with Hippocampal Volume and Cognition Open
The objective of this study was to understand the associations of sleep and cardiorespiratory fitness with hippocampal volume and global cognition among older adults (n = 30, age = 65.8 years, female = 73.3%). Wrist actigraphy provided obj…
View article: The Effects of Exergaming on Attention in Children With Attention Deficit/Hyperactivity Disorder: Randomized Controlled Trial (Preprint)
The Effects of Exergaming on Attention in Children With Attention Deficit/Hyperactivity Disorder: Randomized Controlled Trial (Preprint) Open
BACKGROUND Despite growing evidence showing the effects of exercise and cognitive trainings on enhancing attention, little is known about the combined effects of exergame on attention in children with attention deficit/hyperactivity disor…
View article: The Effects of Exergaming on Executive and Physical Functions in Older Adults With Dementia: Randomized Controlled Trial (Preprint)
The Effects of Exergaming on Executive and Physical Functions in Older Adults With Dementia: Randomized Controlled Trial (Preprint) Open
BACKGROUND Despite increasing interest in the effects of exergaming on cognitive function, little is known about its effects on older adults with dementia. OBJECTIVE The purpose of this is to investigate the effects of exergaming on exe…
View article: Subjective Well-Being and Bilateral Anterior Insula Functional Connectivity After Exercise Intervention in Older Adults With Mild Cognitive Impairment
Subjective Well-Being and Bilateral Anterior Insula Functional Connectivity After Exercise Intervention in Older Adults With Mild Cognitive Impairment Open
While it is well known that exercise training is associated with improvement in subjective well-being among older adults, it is unclear if individuals with cognitive impairment experience the same effects elicited by exercise on subjective…
View article: Differential associations of regional cerebellar volume with gait speed and working memory
Differential associations of regional cerebellar volume with gait speed and working memory Open
The relationship between gait speed and working memory is well-understood in older adults. However, it remains to be determined whether this relationship also exists in younger adults; and there is little known regarding the possible neura…
View article: Mediating Role of Cerebellar Subregion Volume in the Relationship Between Gait Speed and Working Memory
Mediating Role of Cerebellar Subregion Volume in the Relationship Between Gait Speed and Working Memory Open
Introduction: The relationship between gait speed and working memory is well-understood in older adults. However, it remains to be determined whether this relationship also exists in younger adults; and there is little known regarding the …
View article: Hippocampal Functional Connectivity and Memory Performance After Exercise Intervention in Older Adults with Mild Cognitive Impairment
Hippocampal Functional Connectivity and Memory Performance After Exercise Intervention in Older Adults with Mild Cognitive Impairment Open
Background: Exercise training (ET) has neuroprotective effects in the hippocampus, a key brain region for memory that is vulnerable to age-related dysfunction. Objective: We investigated the effects of ET on functional connectivity (FC) of…
View article: Cardiovascular Endurance Modifies the Link between Subjective Sleep Quality and Entorhinal Cortex Thickness in Younger Adults
Cardiovascular Endurance Modifies the Link between Subjective Sleep Quality and Entorhinal Cortex Thickness in Younger Adults Open
Introduction Poor sleep is linked to impaired cognitive function, cortical brain atrophy, and lower cortical thickness. Independently, higher cardiovascular endurance has neuroprotective effects. It remains in question, however, whether ca…
View article: Exercise Training-Related Changes in Cortical Gray Matter Diffusivity and Cognitive Function in Mild Cognitive Impairment and Healthy Older Adults
Exercise Training-Related Changes in Cortical Gray Matter Diffusivity and Cognitive Function in Mild Cognitive Impairment and Healthy Older Adults Open
Individuals with Mild Cognitive Impairment (MCI) are at an elevated risk of dementia and exhibit deficits in cognition and cortical gray matter (GM) volume, thickness, and microstructure. Meanwhile, exercise training appears to preserve br…
View article: Blood pressure‐related differences in brain health between young African Americans and Caucasian Americans
Blood pressure‐related differences in brain health between young African Americans and Caucasian Americans Open
MAP was an important moderator of racial differences in cognitive performance and ERC thickness. Our findings suggest that young AAs may carry a greater hypertension-associated risk for cognitive brain health deficit. Interventions that ad…