Jun Shi
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View article: Curcumin suppresses malignant behaviors of ovarian cancer through regulation of tumor-associated macrophages
Curcumin suppresses malignant behaviors of ovarian cancer through regulation of tumor-associated macrophages Open
View article: Predictive Factors for Fetal Growth Restriction in Patients with Preeclampsia: A Clinical Prediction Study
Predictive Factors for Fetal Growth Restriction in Patients with Preeclampsia: A Clinical Prediction Study Open
The nomogram developed in this study serves as a reliable tool for predicting FGR in pregnant individuals with preeclampsia. Its application could enhance clinical decision-making and improve fetal outcomes in at-risk populations. Further …
View article: Development and Validation of a Predictive Nomogram for Cesarean Delivery in Term Singleton Pregnancies Complicated by Small for Gestational Age Undergoing Labor Induction
Development and Validation of a Predictive Nomogram for Cesarean Delivery in Term Singleton Pregnancies Complicated by Small for Gestational Age Undergoing Labor Induction Open
Objective: This study aimed to identify antenatal and intrapartum risk factors associated with cesarean delivery in term singleton pregnancies complicated by small for gestational age (SGA) and to develop a predictive model. Methods:We con…
View article: Analysis of related factors of CRA in lung cancer patients with different serum iron levels: A retrospective cohort study
Analysis of related factors of CRA in lung cancer patients with different serum iron levels: A retrospective cohort study Open
Background Serum iron, an essential component of hemoglobin (Hb) synthesis in vivo, is a crucial parameter for evaluating the body's iron storage and metabolism capacity. Iron deficiency leads to reduced Hb synthesis in red blood cells and…
View article: Association between glycemic traits and melanoma: a mendelian randomization analysis
Association between glycemic traits and melanoma: a mendelian randomization analysis Open
Background: The causation of Glycemic Traits and risks of Melanoma remains unknown. We used Mendelian Randomization (MR) to assess the links between Glycemic Traits and Melanoma. Method: Pooled data from Genome-Wide Association Studies (GW…
View article: Tissue-induced winding of permanent pacemaker passive-fixation leads
Tissue-induced winding of permanent pacemaker passive-fixation leads Open
View article: Integration of bulk RNA sequencing and single-cell RNA sequencing reveals new natural killer cells promising as biomarkers for meningiomas and glioblastomas
Integration of bulk RNA sequencing and single-cell RNA sequencing reveals new natural killer cells promising as biomarkers for meningiomas and glioblastomas Open
BACKGROUND: Meningioma (MND) and glioblastoma (GBM) are two of the most common tumors in the central nervous system. However, the exploration of common genetic features and molecular mechanisms between MND and GBM is unclear. METHODS: we c…
View article: Research on Electroacupuncture Parameters for Cancer Pain Based on Data Mining
Research on Electroacupuncture Parameters for Cancer Pain Based on Data Mining Open
Background: Cancer pain, a common complication of this disease, has been widely treated by electroacupuncture in recent years. However, there are numerous treatment parameters that are not conducive to clinical translation applications. Th…
View article: Research on electroacupuncture parameters for Cancer Pain based on data mining
Research on electroacupuncture parameters for Cancer Pain based on data mining Open
Background: Cancer pain, a common complication of this disease, has been widely treated by electroacupuncture in recent years. However, there are numerous treatment parameters that are not conducive to clinical translation applications. Th…
View article: Serum Uric Acid to Serum Creatinine Ratio and Risk of Stroke Recurrence in Young Adults with Ischemic Stroke
Serum Uric Acid to Serum Creatinine Ratio and Risk of Stroke Recurrence in Young Adults with Ischemic Stroke Open
SUA/SCr was positively associated with the risk of stroke recurrence among young adults with ischemic stroke. Further prospective studies are warranted to assess the causality between SUA/SCr and the development of stroke recurrence among …
View article: Application of Medical-Nursing Integration Multidisciplinary-Assisted Surgical Wound Nursing Mode in Improving the Quality of Wound Treatment
Application of Medical-Nursing Integration Multidisciplinary-Assisted Surgical Wound Nursing Mode in Improving the Quality of Wound Treatment Open
Surgical treatment is a common clinical intervention for trauma, but postoperative pain and poor nursing lead to slow wound recovery and wound infection. Therefore, it is extremely important to select effective nursing intervention methods…
View article: Evaluation of high-risk factors and the diagnostic value of alpha-fetoprotein in the stratification of primary liver cancer
Evaluation of high-risk factors and the diagnostic value of alpha-fetoprotein in the stratification of primary liver cancer Open
Stratification of PLC was essential for precise diagnoses and benefited from evaluating AFP levels.
View article: Chinese Herbal Medicine (Yiqi-Yangyin-Jiedu Decoction) Combined With Osimertinib as First-Line Treatment in EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer (CATLA-2): A Study Protocol for a Double-Blind Randomized Controlled Trial
Chinese Herbal Medicine (Yiqi-Yangyin-Jiedu Decoction) Combined With Osimertinib as First-Line Treatment in EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer (CATLA-2): A Study Protocol for a Double-Blind Randomized Controlled Trial Open
Background: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) significantly improve the prognosis of non-small cell lung cancer (NSCLC) with EGFR mutation-positive. Although third-generation EGFR-TKI osimertini…
View article: External Treatment With Chinese Herbal Medicine for Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis
External Treatment With Chinese Herbal Medicine for Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis Open
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse reaction of chemotherapy. Many studies have confirmed that traditional Chinese medicine (TCM) has unique advantages for treating CIPN. However, there is no s…
View article: Complementing Tissue Testing With Plasma Mutation Profiling Improves Therapeutic Decision-Making for Patients With Lung Cancer
Complementing Tissue Testing With Plasma Mutation Profiling Improves Therapeutic Decision-Making for Patients With Lung Cancer Open
Background Tissue biopsy is an integral part of the diagnostic approach to lung cancer. It is however invasive and limited by heterogeneity. Liquid biopsies may complement tissue testing by providing additional molecular information and ma…
View article: Correction to: Preoperative Neutrophil‑to‑Lymphocyte Ratio Level is a Predictor of Postoperative Fertility in Infertile Patients with Ovarian Endometrioma
Correction to: Preoperative Neutrophil‑to‑Lymphocyte Ratio Level is a Predictor of Postoperative Fertility in Infertile Patients with Ovarian Endometrioma Open
View article: Chinese Herbal Medicine (Yiqi-Yangyin-Jiedu Decoction) Combined with Osimertinib as First-line Treatment in EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer (CATLA-2): A Study Protocol for a Double-Blind Randomized Controlled Trial
Chinese Herbal Medicine (Yiqi-Yangyin-Jiedu Decoction) Combined with Osimertinib as First-line Treatment in EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer (CATLA-2): A Study Protocol for a Double-Blind Randomized Controlled Trial Open
Background: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) significantly improve the prognosis of non-small cell lung cancer (NSCLC) with EGFR mutation-positive. Although third-generation EGFR-TKI osimertini…
View article: Contribution of Total Screen/Online-Course Time to Asthenopia in Children During COVID-19 Pandemic via Influencing Psychological Stress
Contribution of Total Screen/Online-Course Time to Asthenopia in Children During COVID-19 Pandemic via Influencing Psychological Stress Open
Objectives: During the coronavirus disease 2019 (COVID-19) self-quarantine period, the transition to online-course has profoundly changed the learning modes of millions of school-aged children and put them at an increased risk of asthenopi…
View article: Stratifin Indicates Worse Prognosis and Promotes Hepatocellular Carcinoma Proliferation, Migration, Invasion and EMT By Modulating Wnt/β-Catenin Pathway
Stratifin Indicates Worse Prognosis and Promotes Hepatocellular Carcinoma Proliferation, Migration, Invasion and EMT By Modulating Wnt/β-Catenin Pathway Open
Background: Stratifin (SFN) is closely related to the tumor progression. However, the role of SFN in hepatocellular carcinoma (HCC) is still unknown. The purpose of this study is to investigate the clinical value, biological role and regul…
View article: Complementing Tissue Testing with Plasma mutation Profiling Improves Therapeutic Decision Making for Lung Cancer Patients
Complementing Tissue Testing with Plasma mutation Profiling Improves Therapeutic Decision Making for Lung Cancer Patients Open
Background Tissue biopsy is an integral part of the diagnostic approach to lung cancer. It is however invasive and associated with limitations of tissue heterogeneity. Liquid biopsies may complement tissue testing by providing additional m…
View article: Chinese Herbal Medicine (Yiqi-Yangyin-Jiedu Decoction) Combined With Osimertinib As First-Line Treatment For Advanced Non-Small-Cell Lung Cancer With EGFR Sensitizing Mutation (CATLA-2): A Study Protocol For A Double-Blind Randomized Controlled Trial
Chinese Herbal Medicine (Yiqi-Yangyin-Jiedu Decoction) Combined With Osimertinib As First-Line Treatment For Advanced Non-Small-Cell Lung Cancer With EGFR Sensitizing Mutation (CATLA-2): A Study Protocol For A Double-Blind Randomized Controlled Trial Open
Background: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) significantly improve the prognosis of non-small cell lung cancer (NSCLC) with EGFR sensitizing mutation. Although third-generation EGFR-TKI osimert…
View article: A DNA methylation-associated nomogram predicts the overall survival of osteosarcoma
A DNA methylation-associated nomogram predicts the overall survival of osteosarcoma Open
Numerous reports have demonstrated that DNA methylation may be underlying prognostic biomarkers of cancer. However, few studies indicated that DNA methylation was independent biomarker for osteosarcoma prognosis. We aimed to discover and v…
View article: The effect of comprehensive rehabilitation program plus chemotherapy on quality of life in patients with postoperative non-small-cell lung cancer: study protocol of a multicenter randomized clinical trial
The effect of comprehensive rehabilitation program plus chemotherapy on quality of life in patients with postoperative non-small-cell lung cancer: study protocol of a multicenter randomized clinical trial Open
View article: Associations of Total Screen Time and Online-Course Time with the Risk of Asthenopia Among School-Aged Children During the COVID-19 Quarantine: A Cross-Sectional Survey in Eastern China
Associations of Total Screen Time and Online-Course Time with the Risk of Asthenopia Among School-Aged Children During the COVID-19 Quarantine: A Cross-Sectional Survey in Eastern China Open
View article: CYR61, a potential biomarker of tumor inflammatory response in epithelial ovarian cancer microenvironment of tumor progress
CYR61, a potential biomarker of tumor inflammatory response in epithelial ovarian cancer microenvironment of tumor progress Open
Background Recent studies have found that inflammatory response is involved in the pathogenesis of ovarian cancer. Advanced ovarian cancer is often presented with ascites that is rich in cytokines, inflammatory factors or cancer cells. The…
View article: Survival advantage associated with metformin usage in hepatocellular carcinoma patients with diabetes mellitus receiving radical resection: a propensity score matching analysis
Survival advantage associated with metformin usage in hepatocellular carcinoma patients with diabetes mellitus receiving radical resection: a propensity score matching analysis Open
Background Metformin is associated with improved survival among hepatocellular carcinoma (HCC) patients with diabetes mellitus. However, the role of metformin in the survival of hepatitis B virus (HBV)-related HCC patients with diabetes me…
View article: The Effect of Comprehensive Rehabilitation Program plus Chemotherapy on Quality of Life in Patients with Postoperative Non-Small-Cell Lung Cancer: A study protocol of a multi-center randomized clinical trial
The Effect of Comprehensive Rehabilitation Program plus Chemotherapy on Quality of Life in Patients with Postoperative Non-Small-Cell Lung Cancer: A study protocol of a multi-center randomized clinical trial Open
Background: Comprehensive rehabilitation therapy based on traditional Chinese medicine (TCM) has been widely applied in various cancer treatments in China. Thus far, Chinese herbal medicine (CHM) has been shown to be effective in reducing …
View article: The Effect of Comprehensive Rehabilitation Program plus Chemotherapy on Quality of Life of Patients with Postoperative Non-Small Cell Lung Cancer: A study protocol of multi-center randomized clinical trial
The Effect of Comprehensive Rehabilitation Program plus Chemotherapy on Quality of Life of Patients with Postoperative Non-Small Cell Lung Cancer: A study protocol of multi-center randomized clinical trial Open
Background: Comprehensive rehabilitation therapy based on Traditional Chinese Medicine (TCM) has been widely applied in various cancer treatments in China. Thus far, Chinese herbal medicine (CHM) has been shown to be effective in reducing …
View article: Letrozole for patients with polycystic ovary syndrome
Letrozole for patients with polycystic ovary syndrome Open
This retrospective study investigated the efficacy and safety of letrozole for patients with polycystic ovary syndrome (PCOS). Totally, 136 cases of infertility women with PCOS were analyzed. Of those, 68 patients received letrozole, and w…
View article: Is shift work associated with a higher risk of overweight or obesity? A systematic review of observational studies with meta-analysis
Is shift work associated with a higher risk of overweight or obesity? A systematic review of observational studies with meta-analysis Open
Individuals involved in shift work are more likely to become overweight or obese. Appropriate preventive interventions in the organization of shift schedules according to ergonomic criteria would allow shift workers to avoid potential heal…