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View article: SWE can detect myocardial remodelling in aortic stenosis patients undergoing aortic valve replacement
SWE can detect myocardial remodelling in aortic stenosis patients undergoing aortic valve replacement Open
Background Aortic stenosis (AS) progresses over time with the development of diffuse and eventually replacement fibrosis. Extensive fibrosis is associated with a worse outcome after aortic valve replacement (AVR). Therefore, early markers …
View article: Noninvasive Pressure-Volume Analysis by Three-Dimensional Echocardiography: A Novel Powerful Method for Evaluating Left Ventricular Function
Noninvasive Pressure-Volume Analysis by Three-Dimensional Echocardiography: A Novel Powerful Method for Evaluating Left Ventricular Function Open
Noninvasive PV analysis by three-dimensional echocardiography is feasible and accurate, making PV loop parameters for evaluating LV function accessible for clinical use. Further studies should explore the clinical utility of this method.
View article: The Impact of Valve Stenosis and Replacement on Wave Characteristics in Cardiac Shear Wave Elastography
The Impact of Valve Stenosis and Replacement on Wave Characteristics in Cardiac Shear Wave Elastography Open
Cardiac shear wave elastography (SWE) is a non-invasive technique to assess myocardial stiffness, based on the speed of waves that travel through the heart after valve closure. The wave physics underlying natural SWE remains incompletely u…
View article: Mechanism and Impact of Left Atrial Dyssynchrony on Long-Term Clinical Outcome During Cardiac Resynchronization Therapy
Mechanism and Impact of Left Atrial Dyssynchrony on Long-Term Clinical Outcome During Cardiac Resynchronization Therapy Open
View article: Mechanical dyssynchrony as a selection criterion for cardiac resynchronization therapy: Design of the AMEND‐CRT trial
Mechanical dyssynchrony as a selection criterion for cardiac resynchronization therapy: Design of the AMEND‐CRT trial Open
Aims One third of patients do not improve after cardiac resynchronization therapy (CRT). Septal flash (SF) and apical rocking (ApRock) are deformation patterns observed on echocardiography in most patients eligible for CRT. These markers o…
View article: Cardiac Magnetic Resonance Identifies Responders to Cardiac Resynchronization Therapy with an Assessment of Septal Scar and Left Ventricular Dyssynchrony
Cardiac Magnetic Resonance Identifies Responders to Cardiac Resynchronization Therapy with an Assessment of Septal Scar and Left Ventricular Dyssynchrony Open
Background: The response to cardiac resynchronization therapy (CRT) depends on septal viability and correction of abnormal septal motion. This study investigates if cardiac magnetic resonance (CMR) as a single modality can identify CRT res…
View article: Continuous shear wave measurements for dynamic cardiac stiffness evaluation in pigs
Continuous shear wave measurements for dynamic cardiac stiffness evaluation in pigs Open
Ultrasound-based shear wave elastography is a promising technique to non-invasively assess the dynamic stiffness variations of the heart. The technique is based on tracking the propagation of acoustically induced shear waves in the myocard…
View article: Mechanical Dyssynchrony Combined with Septal Scarring Reliably Identifies Responders to Cardiac Resynchronization Therapy
Mechanical Dyssynchrony Combined with Septal Scarring Reliably Identifies Responders to Cardiac Resynchronization Therapy Open
Background and aim: The presence of mechanical dyssynchrony on echocardiography is associated with reverse remodelling and decreased mortality after cardiac resynchronization therapy (CRT). Contrarily, myocardial scar reduces the effect of…
View article: Continuous shear wave measurements for dynamic cardiac stiffness evaluation in pigs
Continuous shear wave measurements for dynamic cardiac stiffness evaluation in pigs Open
Ultrasound-based shear wave elastography is a promising technique to non-invasively assess the dynamic stiffness variations of the heart. The technique is based on tracking the propagation of acoustically induced shear waves in the myocard…
View article: Erratum to: Electro-energetics of Biventricular, Septal and Conduction System Pacing
Erratum to: Electro-energetics of Biventricular, Septal and Conduction System Pacing Open
[This corrects the article DOI: 10.15420/aer.2021.30.].
View article: Left atrial hyper-strain in dyssynchronous hearts: potential driver for adverse left atrial remodelling
Left atrial hyper-strain in dyssynchronous hearts: potential driver for adverse left atrial remodelling Open
Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): Institute for Surgical Research, Oslo University Hospital. Introduction It was recently shown that left bundle branch block (LBBB) is associated …
View article: Natural shear waves show sequential changes in myocardial stiffness In paediatric multi-inflammatory systemic syndrome post COVID
Natural shear waves show sequential changes in myocardial stiffness In paediatric multi-inflammatory systemic syndrome post COVID Open
Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): Egyptian ministry of research and higher education Background Multi-inflammatory systemic syndrome post COVID infection (MIS-C) …
View article: Should we use a semi-quantitative assessment of apical rocking to predict outcome in CRT patients?
Should we use a semi-quantitative assessment of apical rocking to predict outcome in CRT patients? Open
Funding Acknowledgements Type of funding sources: None. Introduction Apical rocking (AR) is a systolic septal-to-lateral motion of the apex observed on echocardiography in the apical 4-chamber view in some patients with a ventricular condu…
View article: High frame rate speckle tracking echocardiography for the mapping of cardiac mechanical activation sequence
High frame rate speckle tracking echocardiography for the mapping of cardiac mechanical activation sequence Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): KU Leuven. Background Cardiac arrhythmias are a leading cause of worldwide morbidity and mortality, with catheter ablation being an effective …
View article: Characterisation of responder profiles for cardiac resynchronisation therapy based on explainable machine-learning and virtual patient approaches
Characterisation of responder profiles for cardiac resynchronisation therapy based on explainable machine-learning and virtual patient approaches Open
Funding Acknowledgements Type of funding sources: None. Context Cardiac resynchronisation therapy (CRT) is an implant-based therapy applied to patients with a specific heart failure (HF) profile. The characterisation and identification of …
View article: Behaviour of natural myocardial shear waves in children and adolescents: determinants and reproducibility
Behaviour of natural myocardial shear waves in children and adolescents: determinants and reproducibility Open
Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): Egyptian ministry of higher education and research Background Ultrafast echocardiography allows the direct non-invasive assessme…
View article: Mechanical dyssynchrony combined with septal scarring reliably identifies responders to cardiac resynchronization therapy
Mechanical dyssynchrony combined with septal scarring reliably identifies responders to cardiac resynchronization therapy Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Research Foundation Flanders (FWO). Background The presence of mechanical dyssynchrony on echocardiography is associated with reverse remodeling after ca…
View article: Cardiac shear wave elastography can detect myocardial remodelling in LBBB patients undergoing CRT
Cardiac shear wave elastography can detect myocardial remodelling in LBBB patients undergoing CRT Open
Funding Acknowledgements Type of funding sources: None. Background Cardiac shear wave elastography (SWE) allows for the non-invasive assessment of myocardial stiffness via the detection of shear waves travelling through the heart after e.g…
View article: A strain-based LBBB classification predicts the degree of reverse remodeling and outcome in patients with cardiac resynchronization therapy
A strain-based LBBB classification predicts the degree of reverse remodeling and outcome in patients with cardiac resynchronization therapy Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Research Foundation Flanders (FWO). Introduction Septal strain patterns measured by echocardiography reflect the gradual process of left bundle branch bl…
View article: The change in propagation speed of natural shear waves by altering preload might differentiate patients with increased myocardial stiffness
The change in propagation speed of natural shear waves by altering preload might differentiate patients with increased myocardial stiffness Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Research Foundation Flanders - FWO. Background Shear wave (SW) elastography (SWE) is a novel ultrasound-based technique for t…
View article: Serial Non-Invasive Myocardial Work Measurements for Patient Risk Stratification and Early Detection of Cancer Therapeutics-Related Cardiac Dysfunction in Breast Cancer Patients: A Single-Centre Observational Study
Serial Non-Invasive Myocardial Work Measurements for Patient Risk Stratification and Early Detection of Cancer Therapeutics-Related Cardiac Dysfunction in Breast Cancer Patients: A Single-Centre Observational Study Open
Serial transthoracic echocardiographic (TTE) assessment of LVEF and GLS are the gold standard in screening Cancer Therapeutics-Related Cardiac Dysfunction (CTRCD). Non-invasive left-ventricle (LV) pressure–strain loop (PSL) emerged as a no…
View article: Model-based and Unsupervised Machine-learning Approaches for the Characterization of Responder Profiles for Cardiac Resynchronization Therapy
Model-based and Unsupervised Machine-learning Approaches for the Characterization of Responder Profiles for Cardiac Resynchronization Therapy Open
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View article: Scar imaging in the dyssynchronous left ventricle: Accuracy of myocardial metabolism by positron emission tomography and function by echocardiographic strain
Scar imaging in the dyssynchronous left ventricle: Accuracy of myocardial metabolism by positron emission tomography and function by echocardiographic strain Open
View article: Finding New Insights in Cardiac Resynchronization Therapy and the Pathophysiology behind Left Ventricular Dyssynchrony
Finding New Insights in Cardiac Resynchronization Therapy and the Pathophysiology behind Left Ventricular Dyssynchrony Open
Over the past two decades, cardiac resynchronization therapy (CRT) became an established treatment option for patients with symptomatic heart failure [...]
View article: Model-based analysis of myocardial strains in left bundle branch block
Model-based analysis of myocardial strains in left bundle branch block Open
Introduction Although observational studies of patients with left bundle branch block (LBBB) have shown a relation between strain morphologies and responses to cardiac resynchronization therapy (CRT), the evaluation of left ventricle (LV) …
View article: Clinical and Experimental Evidence for a Strain-Based Classification of Left Bundle Branch Block-Induced Cardiac Remodeling
Clinical and Experimental Evidence for a Strain-Based Classification of Left Bundle Branch Block-Induced Cardiac Remodeling Open
Background: Septal strain patterns measured by echocardiography reflect the severity of left bundle branch block (LBBB)-induced left ventricular (LV) dysfunction. We investigated whether these LBBB strain stages predicted the response to c…
View article: Predictors of shear wave propagation speed assessed by shear wave elastography
Predictors of shear wave propagation speed assessed by shear wave elastography Open
Background Cardiac shear wave elastography (SWE) is a novel ultrasound-based method that assesses the propagation speed of shear waves travelling in the myocardium induced by e.g. mitral valve closure (MVC). The propagation speed of these …
View article: Can echocardiography facilitate decision-making to CRT?
Can echocardiography facilitate decision-making to CRT? Open
Introduction Cardiac resynchronization therapy (CRT) remains underused despite its well-established therapeutic effect and clear guidelines. Among various reasons are the lack of referral, the fear of complications and the high therapy cos…
View article: Resynchronization of the left atrium may play an important role in cardiac resynchronization therapy
Resynchronization of the left atrium may play an important role in cardiac resynchronization therapy Open
Introduction Left atrial (LA) dyssynchrony is a predictor of response to cardiac resynchronization therapy (CRT). It is unknown, however, if LA resynchronization contributes to response to CRT. We hypothesize that there is a relationship b…
View article: Reintroducing dyssynchrony significantly increases myocardial stiffness at mitral valve closure
Reintroducing dyssynchrony significantly increases myocardial stiffness at mitral valve closure Open
Background Cardiac shear wave elastography (SWE) allows for the non-invasive assessment of myocardial stiffness via the detection of shear waves. Shear waves are mechanical waves that travel through the heart after for example mitral valve…