Explanipedia

Adenosine regulates CD8 T‐cell priming by inhibition of membrane‐proximal T‐cell receptor signalling Open

Carsten Linnemann, Frank A. Schildberg, Anna Schurich, Linda Diehl, Silke Hegenbarth , et al. · 2009

Summary Adenosine is a well‐described anti‐inflammatory modulator of immune responses within peripheral tissues. Extracellular adenosine accumulates in inflamed and damaged tissues and inhibits the effector functions of various immune cell…

Grb2 and the Non-T Cell Activation Linker NTAL Constitute a Ca2+-Regulating Signal Circuit in B Lymphocytes Open

Björn Stork, Michael Engelke, Jürgen Frey, Václav Hořejšı́, Andrea Hamm-Baarke , et al. · 2004

Differential Modulation of Stimulatory and Inhibitory Fcγ Receptors on Human Monocytes by Th1 and Th2 Cytokines Open

Luminita Pricop, Patricia Redecha, Jean‐Luc Teillaud, Jürgen Frey, Wolf H. Fridman , et al. · 2001

Immune complex-mediated inflammatory responses are initiated by FcγR on phagocytes. We report in this study that an inhibitory receptor, FcγRIIb2, is expressed on circulating human monocytes, and when co-cross-linked with stimulatory FcγR …

Human Aspartyl 3-Hydroxylase: Recombinant Expression and Domain Structure of an Enzyme Critical for Extracellular Proteins. † 627 Open

Bozena Slowinska, Sylwia Zagulska, Jürgen Frey, Patricia I. Chang, Hartmut M. Hananske-Abel · 1997

In Vivo and In Vitro Specificity of Protein Tyrosine Kinases for Immunoglobulin G Receptor (FcγRII) Phosphorylation Open

N Bewarder, V Weinrich, Petra Budde, Dieter Hartmann, Heinrich Flaswinkel , et al. · 1996

Human B cells express four immunoglobulin G receptors, FcgammaRIIa, FcgammaRIIb1, FcgammaRIIb2, and FcgammaRIIc. Coligation of either FcgammaRII isoform with the B-cell antigen receptor (BCR) results in the abrogation of B-cell activation,…

Fc<sub>γ</sub>‐receptor‐mediated changes in the plasma membrane potential induce prostaglandin release from human fibroblasts Open

Jürgen Frey, Michael Janes, Waltraud Engelhardt, E G Afting, Christina Geerds , et al. · 1986

Binding of aggregated human immunoglobulin G (IgG) on diploid human fibroblasts leads to a rapid depolarization of the cells within 1‐2 min. We resolved this membrane potential change into its plasma membrane and mitochondrial membrane com…

The glucose‐induced inactivation of aminopeptidase I in <i>Saccharomyces cerevisiae</i> Open

Jürgen Frey, Klaus‐Heinrich Röhm · 1979

The Reaction of Aminoacylase with Chloromethylketone Analogs of Amino Acids Open

Jürgen Frey, Werner Kördel, Friedhelm Schneider · 1977

1. Aminoacylase is irreversibly inactivated by the chloromethylketone analogs of benzyloxy-carbonyl-L-alanine, L-alanine, L-leucine, L-aspartic acid (β), tosyl-L-phenylalanine and L-leucyl-L-alanine. The kinetics of the inactivation of the…

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