Juriyati Jalil
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View article: Lysicamine in medicinal plants: Biosynthesis and pharmacological activities
Lysicamine in medicinal plants: Biosynthesis and pharmacological activities Open
Numerous studies have highlighted the significant pharmacological activities of lysicamine in combating and ameliorating various diseases. Nevertheless, a comprehensive compilation of the pharmacological properties of lysicamine has not ye…
View article: Alphonsea elliptica (Hook.f. and Thomson) methanol leaves extract obliterates inflammatory processes in LPS-induced human plasma
Alphonsea elliptica (Hook.f. and Thomson) methanol leaves extract obliterates inflammatory processes in LPS-induced human plasma Open
View article: Review of Online Pharmacy Learning Approaches
Review of Online Pharmacy Learning Approaches Open
Sejak beberapa tahun kebelakangan ini, pembelajaran dalam talian (OL) telah muncul sebagai kaedah yang dinamik dan inovatif untuk menyampaikan ilmu pengajaran dengan lebih efektif di institusi pengajian tinggi (IPT), termasuk dalam bidang …
View article: Phytoconstituents and pharmacological activities of Mitrephora species (Annonaceae): a review
Phytoconstituents and pharmacological activities of Mitrephora species (Annonaceae): a review Open
This study reviewed the phytoconstituents and pharmacological properties of 13 Mitrephora species, namely, Mitrephora alba Ridl., Mitrephora celebica Scheff., Mitrephora diversifolia (Span.) Miq., Mitrephora glabra Scheff., Mitrephora heyn…
View article: Phytochemical profile and diverse pharmacology of Garcinia celebica L
Phytochemical profile and diverse pharmacology of Garcinia celebica L Open
View article: Separation and Isolation of a New Hydroxylated Resveratrol Trimer Together with Other Stilbenoid Compounds from the Lianas of Gnetum microcarpum Blume and Their Inhibitory Effects of Prostaglandin E2
Separation and Isolation of a New Hydroxylated Resveratrol Trimer Together with Other Stilbenoid Compounds from the Lianas of Gnetum microcarpum Blume and Their Inhibitory Effects of Prostaglandin E2 Open
A new oligostilbene trimer, malaysianol F (1), together with ten known stilbenes (2–11), were successfully separated and purified from the acetone extract of the lianas of Gnetum microcarpum. Malaysianol D (2) was isolated for the first ti…
View article: Therapeutic Potential of Hibiscus sabdariffa Linn. in Attenuating Cardiovascular Risk Factors
Therapeutic Potential of Hibiscus sabdariffa Linn. in Attenuating Cardiovascular Risk Factors Open
Cardiovascular diseases (CVDs) represent a broad spectrum of diseases afflicting the heart and blood vessels and remain a major cause of death and disability worldwide. CVD progression is strongly associated with risk factors, including hy…
View article: Cardioprotective Properties of Kaempferol: A Review
Cardioprotective Properties of Kaempferol: A Review Open
Cardiac diseases, such as myocardial infarction and heart failure, have become a major clinical problem globally. The accumulating data demonstrate that bioactive compounds with antioxidant and anti-inflammatory properties have favorable e…
View article: Pharmacological activities and mechanisms of action of hypophyllanthin: A review
Pharmacological activities and mechanisms of action of hypophyllanthin: A review Open
Hypophyllanthin is a major lignan present in various Phyllanthus species and has been used as one of the bioactive chemical markers for quality control purposes as it contributes to their diverse pharmacological activities. The objective o…
View article: Parkia speciosa Hassk. Empty Pod Extract Prevents Cardiomyocyte Hypertrophy by Inhibiting MAPK and Calcineurin-NFATC3 Signaling Pathways
Parkia speciosa Hassk. Empty Pod Extract Prevents Cardiomyocyte Hypertrophy by Inhibiting MAPK and Calcineurin-NFATC3 Signaling Pathways Open
Cardiac hypertrophy is an early hallmark during the clinical course of heart failure. Therapeutic strategies aiming to alleviate cardiac hypertrophy via the mitogen-activated protein kinase (MAPK)/calcineurin-nuclear factor of activated T-…
View article: Molecular mechanisms of sacubitril/valsartan in cardiac remodeling
Molecular mechanisms of sacubitril/valsartan in cardiac remodeling Open
Cardiovascular diseases have become a major clinical burden globally. Heart failure is one of the diseases that commonly emanates from progressive uncontrolled hypertension. This gives rise to the need for a new treatment for the disease. …
View article: The Role of PKC-MAPK Signalling Pathways in the Development of Hyperglycemia-Induced Cardiovascular Complications
The Role of PKC-MAPK Signalling Pathways in the Development of Hyperglycemia-Induced Cardiovascular Complications Open
Cardiovascular disease is the most common cause of death among diabetic patients worldwide. Hence, cardiovascular wellbeing in diabetic patients requires utmost importance in disease management. Recent studies have demonstrated that protei…
View article: The Role of Polyphenol in Modulating Associated Genes in Diabetes-Induced Vascular Disorders
The Role of Polyphenol in Modulating Associated Genes in Diabetes-Induced Vascular Disorders Open
Diabetes-induced vascular disorder is considered one of the deadly risk factors among diabetic patients that are caused by persistent hyperglycemia that eventually leads to cardiovascular diseases. Elevated reactive oxygen species (ROS) du…
View article: Anti-Inflammatory and Antioxidant Activity of Syzygium polyanthum (Wight) Walp.
Anti-Inflammatory and Antioxidant Activity of Syzygium polyanthum (Wight) Walp. Open
Syzygium polyanthum has been used as folk medicine to treat ailments related to oxidative stress and inflammation. In this study, the anti-inflammatory and antioxidant activity of stem bark and root bark of the plant were investigated. The…
View article: Genistein: A Review on its Anti-Inflammatory Properties
Genistein: A Review on its Anti-Inflammatory Properties Open
Nowadays, non-resolving inflammation is becoming a major trigger in various diseases as it plays a significant role in the pathogenesis of atherosclerosis, asthma, cancer, obesity, inflammatory bowel disease, chronic obstructive pulmonary …
View article: Extracts of Andrographis paniculata (Burm.f.) Nees Leaves Exert Anti-Gout Effects by Lowering Uric Acid Levels and Reducing Monosodium Urate Crystal-Induced Inflammation
Extracts of Andrographis paniculata (Burm.f.) Nees Leaves Exert Anti-Gout Effects by Lowering Uric Acid Levels and Reducing Monosodium Urate Crystal-Induced Inflammation Open
Andrographis paniculata (Burm.f.) Nees has been found to have anti-inflammatory and immunostimulatory effects. This study was to investigate antihyperuricemic and anti-inflammatory effects of A. paniculata leaf extracts. Andrographolide, 1…
View article: Parkia speciosa Hassk. Empty Pod Extract Alleviates Angiotensin II-Induced Cardiomyocyte Hypertrophy in H9c2 Cells by Modulating the Ang II/ROS/NO Axis and MAPK Pathway
Parkia speciosa Hassk. Empty Pod Extract Alleviates Angiotensin II-Induced Cardiomyocyte Hypertrophy in H9c2 Cells by Modulating the Ang II/ROS/NO Axis and MAPK Pathway Open
Cardiac hypertrophy is characteristic of heart failure in patients who have experienced cardiac remodeling. Many medicinal plants, including Parkia speciosa Hassk., have documented cardioprotective effects against such pathologies. This st…
View article: New Insights into Molecular Mechanism behind Anti-Cancer Activities of Lycopene
New Insights into Molecular Mechanism behind Anti-Cancer Activities of Lycopene Open
Lycopene is a well-known compound found commonly in tomatoes which brings wide range of health benefits against cardiovascular diseases and cancers. From an anti-cancer perspective, lycopene is often associated with reduced risk of prostat…
View article: Rutin Modulates MAPK Pathway Differently from Quercetin in Angiotensin II-Induced H9c2 Cardiomyocyte Hypertrophy
Rutin Modulates MAPK Pathway Differently from Quercetin in Angiotensin II-Induced H9c2 Cardiomyocyte Hypertrophy Open
Rutin is a flavonoid with antioxidant property. It has been shown to exert cardioprotection against cardiomyocyte hypertrophy. However, studies regarding its antihypertrophic property are still lacking, whether it demonstrates similar anti…
View article: Anti-Allergic Rhinitis Effects of Medicinal Plants and Their Bioactive Metabolites via Suppression of the Immune System: A Mechanistic Review
Anti-Allergic Rhinitis Effects of Medicinal Plants and Their Bioactive Metabolites via Suppression of the Immune System: A Mechanistic Review Open
Allergic rhinitis (AR) is a common inflammatory condition of the nasal mucosa and it is an immunoglobulin E–mediated disease. The incidence and prevalence of AR globally have been escalating over recent years. Antihistamines, intranasal co…
View article: Mechanistic Studies of the Antiallergic Activity of Phyllanthus amarus Schum. & Thonn. and Its Compounds
Mechanistic Studies of the Antiallergic Activity of Phyllanthus amarus Schum. & Thonn. and Its Compounds Open
Phyllanthus amarus Schum. & Thonn. (Phyllanthaceae) is a medicinal plant that is commonly used to treat diseases such as asthma, diabetes, and anemia. This study aimed to examine the antiallergic activity of P. amarus extract and its compo…
View article: Chemical Constituents and Biological Activities of Mitrella Kentii (Blume) Miq. Leaf Oil
Chemical Constituents and Biological Activities of Mitrella Kentii (Blume) Miq. Leaf Oil Open
Chemical constituents and biological activities of the Mitrella kentii leaf oil were investigated in this study. Gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) were used to determine the chemical constituents of t…
View article: UPLC-MS-Based Metabolomics Profiling for α-Glucosidase Inhibiting Property of Parkia speciosa Pods
UPLC-MS-Based Metabolomics Profiling for α-Glucosidase Inhibiting Property of Parkia speciosa Pods Open
Parkia speciosa is a food plant that grows indigenously in Southeast Asia. A great deal of interest has been paid to this plant due to its traditional uses in the treatment of several diseases. The pods contain many beneficial secondary me…
View article: Sinensetin: An Insight on Its Pharmacological Activities, Mechanisms of Action and Toxicity
Sinensetin: An Insight on Its Pharmacological Activities, Mechanisms of Action and Toxicity Open
Sinensetin, a plant-derived polymethoxylated flavonoid found in Orthosiphon aristatus var. aristatus and several citrus fruits, has been found to possess strong anticancer activities and a variety of other pharmacological benefits and prom…
View article: Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties
Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties Open
The genus Parkia (Fabaceae, Subfamily, Mimosoideae) comprises about 34 species of mostly evergreen trees widely distributed across neotropics, Asia, and Africa. This review aims to provide an overview of the current status of the species f…
View article: Xanthine oxidase inhibitory activity of a new isocoumarin obtained from Marantodes pumilum var. pumila leaves
Xanthine oxidase inhibitory activity of a new isocoumarin obtained from Marantodes pumilum var. pumila leaves Open
Background In traditional Malay medicine, Marantodes pumilum (Blume) Kuntze (family Primulaceae) is commonly used by women to treat parturition, flatulence, dysentery, dysmenorrhea, gonorrhea, and bone diseases. Preliminary screening of so…
View article: An improved procedure for the isolation of Ribonucleic acid from methicillin-resistant Staphylococcus aureus
An improved procedure for the isolation of Ribonucleic acid from methicillin-resistant Staphylococcus aureus Open
Extraction and purification of ribonucleic acid (RNA) from Gram-positive methicillin resistant Staphylococcus aureus (MRSA) is problematic, because the MRSA has a rigid cell wall that contains lipoteichoic acid and peptidoglycan, thus caus…
View article: Invitro a-amylase Inhibitory Activity and Antioxidant Profile of Carica Papaya Seed Protein Hydrolysate
Invitro a-amylase Inhibitory Activity and Antioxidant Profile of Carica Papaya Seed Protein Hydrolysate Open
Carica papaya, a plant belonging to the Caricaceae family produces pawpaw fruit; a very useful plant commonly found in most of the tropical African countries, with Nigeria being the third largest producer worldwide. Protein hydrolysates fr…
View article: Aktivitas Antioksidan dan Penghambatan Xantin Oksidase Kulit Batang Songi (Dillenia serrata Thunb.)
Aktivitas Antioksidan dan Penghambatan Xantin Oksidase Kulit Batang Songi (Dillenia serrata Thunb.) Open
Songi (Dillenia serrata) is a tree endemic to Southeast Sulawesi and its stem bark been used in folk medicine. Nonetheless, only a handful scientific knowledge regarding chemistry and biological activities has been investigated on the plan…
View article: Anti-hyperuricemic and Anti-inflammatory Effects of Marantodes pumilum as Potential Treatment for Gout
Anti-hyperuricemic and Anti-inflammatory Effects of Marantodes pumilum as Potential Treatment for Gout Open
Marantodes pumilum (Primulaceae) has been used in Malaysian folk medicine to help women regain strength after delivery and for "sickness in the bones." It was previously revealed that its extracts inhibited xanthine oxidase (XO) act…