Jussi Lehtonen
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View article: Competitive gametic traits and their coevolution with strong and slight anisogamy
Competitive gametic traits and their coevolution with strong and slight anisogamy Open
Gamete dynamics (GD) theory for the evolutionary transition from isogamy to anisogamy relies on the biophysics of fertilization, combining the dynamics of gamete limitation and gamete competition with the provisioning requirements of gamet…
View article: Association of fever and infections with the subsequent risk of atopic diseases in children with genetic susceptibility for T1D: Results from the TEDDY cohort study
Association of fever and infections with the subsequent risk of atopic diseases in children with genetic susceptibility for T1D: Results from the TEDDY cohort study Open
Background The increased prevalence of atopic diseases may be due to lifestyle changes affecting our exposure to microbes. We investigated the association between infections, fever, and atopic diseases in a large international birth cohort…
View article: Zygote survival functions: A critical systematisation
Zygote survival functions: A critical systematisation Open
The life cycle of a sexually reproducing species starts from the formation of a zygote by fusion of two gametes. In external fertilisers, the survival of an individual organism from a zygote to an adult is precarious and depends largely on…
View article: Juvenile and total reproductive values for sexual reproduction under any genetic system
Juvenile and total reproductive values for sexual reproduction under any genetic system Open
Reproductive value (RV) is the expected contribution of genes by an individual or class of individuals to the gene pool in the distant future, and it plays a crucial role in understanding adaptation in long-term evolution. Class RVs are li…
View article: The logic of conventional and reversed Bateman gradients
The logic of conventional and reversed Bateman gradients Open
The Bateman gradient is a central concept in sexual selection theory that relates reproductive success to mate number, with important consequences for sex-specific selection. The conventional expectation is that Bateman gradients are steep…
View article: The correlation between anisogamy and sexual selection intensity—the broad theoretical predictions
The correlation between anisogamy and sexual selection intensity—the broad theoretical predictions Open
Darwin and Bateman suggested that precopulatory sexual selection is more intense on males than females, and that this difference is due to anisogamy (i.e., dimorphism in gamete size and number). While a recent paper apparently presents emp…
View article: Sex-specific assumptions and their importance in models of sexual selection
Sex-specific assumptions and their importance in models of sexual selection Open
Sexual selection is a field coloured by tension and contrasting views. One contested claim is the causal link from the definition of the sexes (anisogamy) to divergent selection on the sexes. Does theory truly engage with this claim? We su…
View article: Assessment of Enterovirus Antibodies during Early Childhood Using a Multiplex Immunoassay
Assessment of Enterovirus Antibodies during Early Childhood Using a Multiplex Immunoassay Open
Enteroviruses cause a wide variety of symptoms ranging from a mild rash and the common cold to paralyzing poliomyelitis. While enteroviruses are among the most common human pathogens, there is a need for new, affordable serological assays …
View article: Kin selection in interactions between gametes: Gamete competition, gamete limitation, and sex allocation
Kin selection in interactions between gametes: Gamete competition, gamete limitation, and sex allocation Open
Kin selection on one hand, and gamete interactions in post-ejaculatory sexual selection on the other are two major research themes that have risen to prominence over the past half century and have simultaneously developed into central fiel…
View article: HLA‐DQ‐conferred risk for type 1 diabetes does not alter neutralizing antibody response to a widely used enterovirus vaccine, the poliovirus vaccine
HLA‐DQ‐conferred risk for type 1 diabetes does not alter neutralizing antibody response to a widely used enterovirus vaccine, the poliovirus vaccine Open
This study investigated whether children with HLA‐DQ‐conferred risk for type 1 diabetes (T1D) have an altered immune response to the widely‐used enterovirus vaccine, namely poliovirus vaccine, and whether initiation of autoimmunity to panc…
View article: Evolutionary game theory of continuous traits from a causal perspective
Evolutionary game theory of continuous traits from a causal perspective Open
Modern evolutionary game theory typically deals with the evolution of continuous, quantitative traits under weak selection, allowing the incorporation of rich biological detail and complicated nonlinear interactions. While these models are…
View article: Half a century of evolutionary games: a synthesis of theory, application and future directions
Half a century of evolutionary games: a synthesis of theory, application and future directions Open
nonPeerReviewed
View article: Individual- and group-level sex ratios under local mate competition: consequences of infanticide and reproductive dominance
Individual- and group-level sex ratios under local mate competition: consequences of infanticide and reproductive dominance Open
Extremely female-biased sex ratios of parasitoid wasps in multiple-foundress groups challenges evolutionary theory which predicts diminishing bias as foundress numbers increase. Recent theory based on foundress cooperation has achieved qua…
View article: Serum 25-hydroxyvitamin D and fatty acids in relation to the risk of microbial infections in children: The TRIGR Divia study
Serum 25-hydroxyvitamin D and fatty acids in relation to the risk of microbial infections in children: The TRIGR Divia study Open
In young children with increased susceptibility to type 1 diabetes, long-chain n-3 PUFAs may influence the risk of viral infections and immune response against the infections. However, this association may depend on the type of virus sugge…
View article: Bateman gradients from first principles
Bateman gradients from first principles Open
View article: Welfare effect of substitute sites for coastal recreation – evidence from the Baltic Sea
Welfare effect of substitute sites for coastal recreation – evidence from the Baltic Sea Open
Omission of substitute sites in travel cost analysis can cause an overestimation of recreational benefits. Only few analyses have included substitutes, partly because of the difficulty in defining an appropriate set of substitutes. We exam…
View article: Rakenteiden törmäys. Taiteellinen toimintatutkimus Teatterikorkeakoulun ja Sibelius-Akatemian yleisökontaktikurssista
Rakenteiden törmäys. Taiteellinen toimintatutkimus Teatterikorkeakoulun ja Sibelius-Akatemian yleisökontaktikurssista Open
Colliding structures: Artistic action research on audience contact course at the Sibelius and Theatre Academies. This article focuses on a period between 2018–2019 when students from the Sibelius Academy were invited to take part in an aud…
View article: Association of different enteroviruses with atopy and allergic diseases in early childhood
Association of different enteroviruses with atopy and allergic diseases in early childhood Open
Background Enterovirus (EV) infections, being among the most prevalent viruses worldwide, have been associated with reduced risk of allergic diseases. We sought to determine the association between EVs and allergic sensitization and diseas…
View article: Author response for "Association of different enteroviruses with atopy and allergic diseases in early childhood"
Author response for "Association of different enteroviruses with atopy and allergic diseases in early childhood" Open
View article: Land Cover of Early Life Environment Modulates the Risk of Type 1 Diabetes
Land Cover of Early Life Environment Modulates the Risk of Type 1 Diabetes Open
OBJECTIVE Environmental microbial exposures have been implicated to protect against immune-mediated diseases such as type 1 diabetes. Our objective was to study the association of land cover around the early-life dwelling with the developm…
View article: Land Cover of Early Life Environment Modulates the Risk of Type 1 Diabetes
Land Cover of Early Life Environment Modulates the Risk of Type 1 Diabetes Open
OBJECTIVE Environmental microbial exposures have been implicated to protect against immune-mediated diseases such as type 1 diabetes. Our objective was to study the association of land cover around the early-life dwelling with the developm…
View article: Land Cover of Early-Life Environment Modulates the Risk of Type 1 Diabetes
Land Cover of Early-Life Environment Modulates the Risk of Type 1 Diabetes Open
OBJECTIVE Environmental microbial exposures have been implicated to protect against immune-mediated diseases such as type 1 diabetes. Our objective was to study the association of land cover around the early-life dwelling with the developm…
View article: Evolution of Anisogamy in Organisms with Parthenogenetic Gametes
Evolution of Anisogamy in Organisms with Parthenogenetic Gametes Open
The two sexes are defined by the sizes of the gametes they produce, anisogamy being the state with two differing gamete sizes (hence, females and males). The origin of this divergence has received much research interest, both theoretically…
View article: Fisher's principle remains a plausible explanation for human sex ratio evolution. A Comment on: Zietsch <i>et al</i> . 2020
Fisher's principle remains a plausible explanation for human sex ratio evolution. A Comment on: Zietsch <i>et al</i> . 2020 Open
This is a comment on a previously published article in the same journal: Zietsch BP, Walum H, Lichtenstein P, Verweij KJH, Kuja-Halkola R. 2020 No genetic contribution to variation in human offspring sex ratio: a total population study of …
View article: The association of different enteroviruses with atopy and allergic diseases in early childhood
The association of different enteroviruses with atopy and allergic diseases in early childhood Open
Background: Enterovirus (EV) infections, being among the most prevalent viruses worldwide, have been associated with reduced risk of allergic diseases. We sought to determine the association of EVs with allergic sensitization and disease i…
View article: The Legacy of Parker, Baker and Smith 1972: Gamete Competition, the Evolution of Anisogamy, and Model Robustness
The Legacy of Parker, Baker and Smith 1972: Gamete Competition, the Evolution of Anisogamy, and Model Robustness Open
The evolution of anisogamy or gamete size dimorphism is a fundamental transition in evolutionary history, and it is the origin of the female and male sexes. Although mathematical models attempting to explain this transition have been publi…
View article: Immunomodulatory Effects of Rhinovirus and Enterovirus Infections During the First Year of Life
Immunomodulatory Effects of Rhinovirus and Enterovirus Infections During the First Year of Life Open
Early childhood infections have been implicated in the development of immune-mediated diseases, such as allergies, asthma, and type 1 diabetes. We set out to investigate the immunomodulatory effects of early viral infections experienced be…
View article: Enterovirus Infections Are Associated With the Development of Celiac Disease in a Birth Cohort Study
Enterovirus Infections Are Associated With the Development of Celiac Disease in a Birth Cohort Study Open
Enterovirus and adenovirus infections have been linked to the development of celiac disease. We evaluated this association in children who developed biopsy-proven celiac disease (N = 41) during prospective observation starting from birth, …
View article: Full programme
Full programme Open
View article: Correction: Saarinen, N.V.V., et al. Multiplexed High-Throughput Serological Assay for Human Enteroviruses. Microorganismis 2020, 8, 963
Correction: Saarinen, N.V.V., et al. Multiplexed High-Throughput Serological Assay for Human Enteroviruses. Microorganismis 2020, 8, 963 Open
The authors wish to make the following corrections to this paper [...]