Justin M. Saunders
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View article: Efficacy and safety of catheter ablation for atrial arrhythmias in patients with cardiac amyloidosis: a systematic review and meta-analysis
Efficacy and safety of catheter ablation for atrial arrhythmias in patients with cardiac amyloidosis: a systematic review and meta-analysis Open
Introduction Cardiac amyloidosis (CA) is a restrictive cardiomyopathy characterized by amylin deposits in the heart muscle. While the prevalence of atrial arrhythmias in CA is high, the data regarding the outcomes of catheter ablation in t…
View article: Reduced alcohol preference and intake after fecal transplant in patients with alcohol use disorder is transmissible to germ-free mice
Reduced alcohol preference and intake after fecal transplant in patients with alcohol use disorder is transmissible to germ-free mice Open
View article: Glucocorticoid receptor dysregulation underlies 5-HT2AR-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model
Glucocorticoid receptor dysregulation underlies 5-HT2AR-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model Open
View article: Glucocorticoid receptor dysregulation underlies 5-HT<sub>2A</sub>receptor-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model
Glucocorticoid receptor dysregulation underlies 5-HT<sub>2A</sub>receptor-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model Open
Prenatal environmental insults increase the risk of neurodevelopmental psychiatric conditions in the offspring. Structural modifications of dendritic spines are central to brain development and plasticity. Using maternal immune activation …
View article: Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice
Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice Open
View article: Sex-specific effects of psychedelics on prepulse inhibition of startle in 129S6/SvEv mice
Sex-specific effects of psychedelics on prepulse inhibition of startle in 129S6/SvEv mice Open
View article: Prolonged epigenetic and synaptic plasticity alterations following single exposure to a psychedelic in mice
Prolonged epigenetic and synaptic plasticity alterations following single exposure to a psychedelic in mice Open
Clinical evidence suggests a potential therapeutic effect of classic psychedelics for the treatment of depression. The most outstanding and distinct characteristic is the rapid and sustained antidepressant action with one single exposure t…
View article: Increased thin-spine density in frontal cortex pyramidal neurons in a genetic rat model of schizophrenia-relevant features
Increased thin-spine density in frontal cortex pyramidal neurons in a genetic rat model of schizophrenia-relevant features Open
View article: Sources of Variability in Measurements of Cardiac Troponin T in a Community-Based Sample: The Atherosclerosis Risk in Communities Study
Sources of Variability in Measurements of Cardiac Troponin T in a Community-Based Sample: The Atherosclerosis Risk in Communities Study Open
BACKGROUND: Application of cardiac troponin T (cTnT) as a marker of myocyte damage requires knowledge of its measurement variability. Using a highly sensitive assay for measurement, we evaluated the long-term storage stability of plasma cT…
View article: Interclass GPCR heteromerization affects localization and trafficking
Interclass GPCR heteromerization affects localization and trafficking Open
Serotonin 5-HT 2A receptors heterodimerize with mGluR2 and trigger internalization.
View article: Gut microbiota manipulation during the prepubertal period shapes behavioral abnormalities in a mouse neurodevelopmental disorder model
Gut microbiota manipulation during the prepubertal period shapes behavioral abnormalities in a mouse neurodevelopmental disorder model Open
Previous studies demonstrate an association between activation of the maternal immune system during pregnancy and increased risk of neurodevelopmental psychiatric conditions, such as schizophrenia and autism, in the offspring. Relatively r…
View article: The Toll of Hyperammonemia on the Brain
The Toll of Hyperammonemia on the Brain Open
Acute liver failure (ALF) is a devastating disease characterized by inflammation, immune activation, and hyperammonemia.1Bernal W. Wendon J. Acute liver failure.N Engl J Med. 2013; 369: 2525-2534Crossref PubMed Scopus (727) Google Scholar …
View article: Role of mGlu2 in the 5-HT2A receptor-dependent antipsychotic activity of clozapine in mice
Role of mGlu2 in the 5-HT2A receptor-dependent antipsychotic activity of clozapine in mice Open
View article: HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice
HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice Open
View article: Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects
Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects Open
View article: Validation of schizophrenia gene expression profile in a preclinical model of maternal infection during pregnancy
Validation of schizophrenia gene expression profile in a preclinical model of maternal infection during pregnancy Open