Explanipedia

Retinal Vessel Diameters Change Within 1 Hour of Intracranial Pressure Lowering Open

Heather E. Moss, Gautam Vangipuram, Justin Wanek, Mahnaz Shahidi · 2018

The relationship between initial ICP and direction of retinal vessel size change following ICP lowering suggests a potential effect of ICP on cerebral and ocular hemodynamics that is relevant when considering the use of retinal vessel meas…

Retinal Vascular and Oxygen Temporal Dynamic Responses to Light Flicker in Humans Open

Anthony E. Felder, Justin Wanek, Norman P. Blair, Mahnaz Shahidi · 2017

Mathematical modeling revealed considerable differences in the time courses of changes among metrics during flicker, indicating flicker duration should be considered separately for each metric. Future application of this method may be usef…

Retinal Oximetry and Vessel Diameter Measurements With a Commercially Available Scanning Laser Ophthalmoscope in Diabetic Retinopathy Open

Norman P. Blair, Justin Wanek, Anthony E. Felder, Charlotte E. Joslin, Jacob K. Kresovich , et al. · 2017

Alterations in retinal vascular diameters and SO2 by diabetic retinopathy stage can be detected with a widely available SLO, and covariates such as race can influence the results.

A Method for Combined Retinal Vascular and Tissue Oxygen Tension Imaging Open

Anthony E. Felder, Justin Wanek, Michael Tan, Norman P. Blair, Mahnaz Shahidi · 2017

The retina requires adequate oxygenation to maintain cellular metabolism and visual function. Inner retinal oxygen metabolism is directly related to retinal vascular oxygen tension (PO 2 ) and inner retinal oxygen extraction fraction (OEF)…

A Method for Combined Retinal Vascular and Tissue Oxygen Tension Imaging Open

Mahnaz Shahidi, Anthony E. Felder, Justin Wanek, Norman P. Blair, Michael Tan · 2017

Quantitative volumetric analysis of retinal tissue oxygen tension Open

Anthony E. Felder, Justin Wanek, Norman P. Blair, Mahnaz Shahidi · 2017

Association between Visual Acuity and Retinal Layer Metrics in Diabetic Retinopathy by Enface OCT Imaging Open

Lakshmi Priya Ranagarju, Michael Tan, Justin Wanek, Norman P. Blair, Jennifer I. Lim , et al. · 2017

Assessment of Conjunctival Microvascular Hemodynamics in Stages of Diabetic Microvasculopathy Open

Maziyar M. Khansari, Justin Wanek, Michael Tan, Charlotte E. Joslin, Jacob K. Kresovich , et al. · 2017

Inner Retinal Oxygen Delivery, Metabolism, and Extraction Fraction in Ins2<sup>Akita</sup> Diabetic Mice Open

Norman P. Blair, Justin Wanek, Anthony E. Felder, Katherine C. Brewer, Charlotte E. Joslin , et al. · 2016

Inner retinal MO2 was maintained in diabetic Akita mice indicating that elevation of the OEF adequately compensated for reduced DO2 and prevented oxidative metabolism from being limited by hypoxia.

The Effects of Diabetic Retinopathy Stage and Light Flicker on Inner Retinal Oxygen Extraction Fraction Open

Anthony E. Felder, Justin Wanek, Norman P. Blair, Charlotte E. Joslin, Katherine C. Brewer , et al. · 2016

The findings of alterations in retinal D, SO2, OEF, and their light flicker-induced responses at stages of DR may be useful to elucidate the pathophysiology of DR.

Quantitative mapping of retinal layer thickness and interface disruption by OCT enface imaging Open

Lakshmi Priya Rangaraju, Michael Tan, Justin Wanek, Norman P. Blair, Jennifer I. Lim , et al. · 2016

Inner retinal oxygen delivery and metabolism following ischemia/reperfusion injury in rat Open

Michael Tan, Anthony E. Felder, Justin Wanek, Norman P. Blair, Mahnaz Shahidi · 2016

Alterations in retinal tissue oxygen tension due to light flicker stimulation in rat Open

Norman P. Blair, Michael Tan, Anthony E. Felder, Pang-yu Teng, Justin Wanek , et al. · 2016

Alterations in Retinal Layer Thickness and Reflectance at Different Stages of Diabetic Retinopathy by En Face Optical Coherence Tomography Open

Justin Wanek, Norman P. Blair, Felix Y. Chau, Jennifer I. Lim, Yannek I. Leiderman , et al. · 2016

Depth and spatially resolved retinal thickness and reflectance measurements are potential biomarkers for assessment and monitoring of DR.

Enface Thickness Mapping and Reflectance Imaging of Retinal Layers in Diabetic Retinopathy Open

Andrew Francis, Justin Wanek, Jennifer I. Lim, Mahnaz Shahidi · 2015

Enface thickness mapping and reflectance imaging of retinal layers is a potentially useful method for quantifying the spatial and axial extent of pathologies due to DR.

Inner Retinal Oxygen Extraction Fraction in Response to Light Flicker Stimulation in Humans Open

Anthony E. Felder, Justin Wanek, Norman P. Blair, Mahnaz Shahidi · 2015

Oxygen extraction fraction before and during light flicker stimulation is reported in human subjects for the first time. Oxygen extraction fraction decreased during light flicker stimulation, indicating the change in DO2 exceeded that of M…

Effects of Optical Blur Reduction on Equivalent Intrinsic Blur Open

Ali Kord Valeshabad, Justin Wanek, J. Jason McAnany, Mahnaz Shahidi · 2015

Reduction in equivalent intrinsic blur was greater than the reduction in optical blur after AO correction of wavefront error. This finding implies that visual acuity in subjects with high equivalent intrinsic blur can be improved beyond th…

Changes in Conjunctival Hemodynamics Predict Albuminuria in Sickle Cell Nephropathy Open

Ali Kord Valeshabad, Justin Wanek, Santosh L. Saraf, Bruce I. Gaynes, Victor R. Gordeuk , et al. · 2015

Background: Albuminuria is an early manifestation of deterioration in renal function in subjects with sickle cell disease (SCD). Hyperfiltration may be an early mechanism for kidney damage in SCD. The purpose of the current s…

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