Justin Z. Amarin
YOU?
Author Swipe
View article: Comparison of Sofia 2 Respiratory Syncytial Virus Fluorescent Immunoassay to Real‐Time Polymerase Chain Reaction Assay in Children Under Two Years Old Hospitalized With Acute Respiratory Illness in Amman, Jordan: A Cross‐Sectional Study
Comparison of Sofia 2 Respiratory Syncytial Virus Fluorescent Immunoassay to Real‐Time Polymerase Chain Reaction Assay in Children Under Two Years Old Hospitalized With Acute Respiratory Illness in Amman, Jordan: A Cross‐Sectional Study Open
Background and Aims Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infection (ARI) in children, particularly in low‐ and middle‐income countries. Rapid diagnosis is important for management and infection control.…
View article: Adenovirus Types in US Children Hospitalized or Seen in the Emergency Department With Acute Respiratory Illness, 2016–2019
Adenovirus Types in US Children Hospitalized or Seen in the Emergency Department With Acute Respiratory Illness, 2016–2019 Open
Background Human adenovirus (HAdV) is a common cause of pediatric acute respiratory illness (ARI), contributing to 5–13% of cases worldwide. Clinical manifestations vary by HAdV species and type; therefore, delineating type-specific diseas…
View article: Changes in Antiviral Prescribing for Children With Influenza in US Emergency Departments
Changes in Antiviral Prescribing for Children With Influenza in US Emergency Departments Open
Importance Despite national recommendations, antiviral prescribing in emergency departments (EDs) for children at higher risk of severe influenza, such as those younger than 5 years and those with specific underlying conditions, remains lo…
View article: Epidemiology of respiratory syncytial virus in young, hospitalized children in Jordan: a prospective viral surveillance study
Epidemiology of respiratory syncytial virus in young, hospitalized children in Jordan: a prospective viral surveillance study Open
Respiratory syncytial virus (RSV) is a leading cause of hospitalization in young children. Understanding RSV burden and seasonality is crucial for implementing effective preventive strategies, especially in the wake of disruptions related …
View article: Antiviral Prescription in Children With Influenza in US Emergency Departments: New Vaccine Surveillance Network (NVSN), 2016–2020
Antiviral Prescription in Children With Influenza in US Emergency Departments: New Vaccine Surveillance Network (NVSN), 2016–2020 Open
Background Influenza contributes to a high burden of pediatric emergency department (ED) visits annually. Guidelines recommend outpatient antiviral treatment for children at higher risk of severe influenza and recommend considering treatme…
View article: Vaccine Adjuvants in the Immunocompromised Host: Science, Safety, and Efficacy
Vaccine Adjuvants in the Immunocompromised Host: Science, Safety, and Efficacy Open
Vaccine adjuvants are essential for enhancing immune responses to vaccines, particularly in immunocompromised populations who typically demonstrate suboptimal responses to standard vaccination. This narrative review evaluates the safety an…
View article: Life-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children
Life-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children Open
BACKGROUND: Clinical differences between critical illness from influenza infection vs coronavirus disease 2019 (COVID-19) have not been well characterized in pediatric patients. METHODS: We compared demographics, clinical characteristics, …
View article: Antibiotic use among young, hospitalized children in Jordan, 2010–2023
Antibiotic use among young, hospitalized children in Jordan, 2010–2023 Open
Inappropriate antibiotic use drives antimicrobial resistance, a global health threat causing increased morbidity and mortality. Understanding antibiotic practices in low-resource settings is essential to identify intervention targets. This…
View article: Incidence of biliary atresia in the United States before and during the COVID‐19 pandemic
Incidence of biliary atresia in the United States before and during the COVID‐19 pandemic Open
Objectives The etiology of biliary atresia (BA) is unclear and potentially involves viral triggers. We aimed to compare the incidence of BA in the United States before and during the coronavirus disease 2019 (COVID‐19) pandemic, focusing o…
View article: Epidemiology and Outcome of Primary Central Nervous System Tumors Treated at King Hussein Cancer Center
Epidemiology and Outcome of Primary Central Nervous System Tumors Treated at King Hussein Cancer Center Open
Background and Objectives: Primary central nervous system (CNS) tumors are often associated with relatively poor outcomes. Data on the epidemiology and outcome of CNS tumors in Jordan are scarce. We aim to report the epidemiology and outco…
View article: P-670. Differences in Adenovirus Type Detection in Children with Acute Respiratory Illness versus Healthy Controls: New Vaccine Surveillance Network (NVSN) 2016-2019
P-670. Differences in Adenovirus Type Detection in Children with Acute Respiratory Illness versus Healthy Controls: New Vaccine Surveillance Network (NVSN) 2016-2019 Open
Background Human adenovirus (HAdV) is a common cause of acute respiratory illness (ARI) in children, ranging from asymptomatic to life-threatening disease. While previous studies have examined asymptomatic vs HAdV ARI infections, few have …
View article: P-2366. Influenza-Specific Antiviral Use in Hospitalized Children Before and During the COVID-19 Pandemic, New Vaccine Surveillance Network (2016–2023)
P-2366. Influenza-Specific Antiviral Use in Hospitalized Children Before and During the COVID-19 Pandemic, New Vaccine Surveillance Network (2016–2023) Open
Background Influenza-specific antivirals are recommended for all hospitalized children with suspected or confirmed influenza. However, antiviral use remains suboptimal. We investigated antiviral use in children hospitalized with influenza …
View article: P-1193. Epidemiology of Respiratory Syncytial Virus in Young, Hospitalized Children in Jordan: A Prospective Viral Surveillance Study
P-1193. Epidemiology of Respiratory Syncytial Virus in Young, Hospitalized Children in Jordan: A Prospective Viral Surveillance Study Open
Background Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infections in young children worldwide. With the recent wave of regulatory approvals and authorizations for nirsevimab and maternal RSV vaccines across se…
View article: P-1209. Changes in Antiviral Prescription for Children with Influenza in U.S. Emergency Departments During the COVID-19 Pandemic: New Vaccine Surveillance Network (NVSN), 2016-2023
P-1209. Changes in Antiviral Prescription for Children with Influenza in U.S. Emergency Departments During the COVID-19 Pandemic: New Vaccine Surveillance Network (NVSN), 2016-2023 Open
Background Despite recommendations from CDC and ACIP, antiviral prescription for children who are at higher risk of severe influenza (including those < 5 years and those with certain underlying conditions) in emergency departments (EDs)…
View article: P-25. Evaluating the Immunogenicity and Safety of Either Two High-Dose or Two Standard-Dose Influenza Vaccines Over Two Consecutive Seasons in Adult Hematopoietic Cell Transplant Recipients
P-25. Evaluating the Immunogenicity and Safety of Either Two High-Dose or Two Standard-Dose Influenza Vaccines Over Two Consecutive Seasons in Adult Hematopoietic Cell Transplant Recipients Open
Background Adult hematopoietic cell transplant (HCT) recipients are at high risk of influenza complications but have suboptimal immune responses to influenza vaccines. Our previous phase II trial in adult HCT recipients demonstrated that t…
View article: Antiviral Use Among Children Hospitalized With Laboratory-Confirmed Influenza Illness: A Prospective, Multicenter Surveillance Study
Antiviral Use Among Children Hospitalized With Laboratory-Confirmed Influenza Illness: A Prospective, Multicenter Surveillance Study Open
Background Guidelines state that all hospitalized children with suspected or confirmed influenza receive prompt treatment with influenza-specific antivirals. We sought to determine the frequency of, and factors associated with, antiviral r…
View article: Seasonal influenza vaccination: Attitudes and practices of healthcare providers in Jordan
Seasonal influenza vaccination: Attitudes and practices of healthcare providers in Jordan Open
Background Influenza is associated with significant global morbidity and mortality, with vaccination being the primary preventive strategy. Despite recommendations, influenza vaccine uptake among healthcare providers (HCPs) remains subopti…
View article: Selection bias may compromise our understanding of the clinical significance of the co-detection of respiratory viruses
Selection bias may compromise our understanding of the clinical significance of the co-detection of respiratory viruses Open
View article: Immunogenicity and Reactogenicity of High- or Standard-Dose Influenza Vaccine in a Second Consecutive Influenza Season
Immunogenicity and Reactogenicity of High- or Standard-Dose Influenza Vaccine in a Second Consecutive Influenza Season Open
Background Pediatric hematopoietic cell transplant (HCT) recipients are at high risk for morbidity from influenza virus infection. We demonstrated in a primary phase 2 randomized controlled trial that 2 post-HCT doses of high-dose trivalen…
View article: Evaluating Acute Viral Gastroenteritis Severity: Modified Vesikari and Clark Scoring Systems
Evaluating Acute Viral Gastroenteritis Severity: Modified Vesikari and Clark Scoring Systems Open
OBJECTIVE Acute gastroenteritis (AGE) is the second leading cause of death in children worldwide. Objectively evaluating disease severity is critical for assessing future interventions. We used data from a large, prospective surveillance s…
View article: Accuracy of Influenza <i>ICD-10</i> Diagnosis Codes in Identifying Influenza Illness in Children
Accuracy of Influenza <i>ICD-10</i> Diagnosis Codes in Identifying Influenza Illness in Children Open
Importance Studies of influenza in children commonly rely on coded diagnoses, yet the ability of International Classification of Diseases, Ninth Revision codes to identify influenza in the emergency department (ED) and hospital is highly v…
View article: Infectious Diseases Society of America Guidelines on the Diagnosis of Coronavirus Disease 2019: Serologic Testing
Infectious Diseases Society of America Guidelines on the Diagnosis of Coronavirus Disease 2019: Serologic Testing Open
Background The role of serologic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved during the pandemic as seroprevalence in global populations has increased. The Infectious Diseases Society of America con…
View article: Lymph node ratio is a more robust predictor of overall survival than N stage in stage III colorectal adenocarcinoma
Lymph node ratio is a more robust predictor of overall survival than N stage in stage III colorectal adenocarcinoma Open
View article: Immunophenotypic predictors of influenza vaccine immunogenicity in pediatric hematopoietic cell transplant recipients
Immunophenotypic predictors of influenza vaccine immunogenicity in pediatric hematopoietic cell transplant recipients Open
Pediatric hematopoietic cell transplant (HCT) recipients exhibit poor serologic responses to influenza vaccination early after transplant. To facilitate the optimization of influenza vaccination timing, we sought to identify B- and T-cell …
View article: Seasonality, Clinical Characteristics, and Outcomes of Respiratory Syncytial Virus Disease by Subtype Among Children Aged &lt;5 Years: New Vaccine Surveillance Network, United States, 2016–2020
Seasonality, Clinical Characteristics, and Outcomes of Respiratory Syncytial Virus Disease by Subtype Among Children Aged <5 Years: New Vaccine Surveillance Network, United States, 2016–2020 Open
Background Respiratory syncytial virus (RSV) is a leading cause of acute respiratory illnesses in children. RSV can be broadly categorized into 2 major subtypes: A and B. RSV subtypes have been known to cocirculate with variability in diff…
View article: Clinical prediction model: Multisystem inflammatory syndrome in children versus Kawasaki disease
Clinical prediction model: Multisystem inflammatory syndrome in children versus Kawasaki disease Open
Background Multisystem inflammatory syndrome in children (MIS‐C) is a rare but serious complication of severe acute respiratory syndrome coronavirus 2 infection. Features of MIS‐C overlap with those of Kawasaki disease (KD). Objective The …
View article: Provider-ordered viral testing and antibiotic administration practices among children with acute respiratory infections across healthcare settings in Nashville, Tennessee
Provider-ordered viral testing and antibiotic administration practices among children with acute respiratory infections across healthcare settings in Nashville, Tennessee Open
Objective: Evaluate the association between provider-ordered viral testing and antibiotic treatment practices among children discharged from an ED or hospitalized with an acute respiratory infection (ARI). Design: Active, prospective ARI s…
View article: The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Molecular Diagnostic Testing (December 2023)
The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Molecular Diagnostic Testing (December 2023) Open
Accurate molecular diagnostic tests are necessary for confirming a diagnosis of coronavirus disease 2019 (COVID-19) and for identifying asymptomatic carriage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The number of av…
View article: 1100. Cellular Immunophenotypic Predictors of Influenza Vaccine Immunogenicity in Pediatric Hematopoietic Cell Transplant Recipients
1100. Cellular Immunophenotypic Predictors of Influenza Vaccine Immunogenicity in Pediatric Hematopoietic Cell Transplant Recipients Open
Background Pediatric hematopoietic cell transplant recipients (PHCTRs) have poor serologic responses to influenza vaccination. While absolute numbers of circulating B and T cells are important predictors of response, our goal was to identi…
View article: 2644. Presence of Respiratory Viruses in the Upper Respiratory Tract of Febrile Infants ≤90 Days Old is Associated with Lower Prevalence of Invasive Bacterial Infection
2644. Presence of Respiratory Viruses in the Upper Respiratory Tract of Febrile Infants ≤90 Days Old is Associated with Lower Prevalence of Invasive Bacterial Infection Open
Background Infants ≤ 90 days old are at increased risk of severe disease from both viral and bacterial pathogens. Differentiating between these two etiologies has long presented a diagnostic challenge and has resulted in many risk algorith…