Justyn W. Regini
YOU?
Author Swipe
View article: Do retinal implants provide long-term efficacy, safety and improve quality of life? A systematic review
Do retinal implants provide long-term efficacy, safety and improve quality of life? A systematic review Open
Background: Retinal implants have emerged as interventions to partially restore functional vision such as light perception, motion detection or object localisation in patients with severe vision loss from degenerative retinal conditions, i…
View article: Human iPSC-Derived Lens Organoids Recapitulate Lens Development and Morphogenesis In Vitro
Human iPSC-Derived Lens Organoids Recapitulate Lens Development and Morphogenesis In Vitro Open
View article: Membrane structures and functional correlates in the bi-segmented eye lens of the cephalopod
Membrane structures and functional correlates in the bi-segmented eye lens of the cephalopod Open
The cephalopod eye lens is unique because it has evolved as a compound structure with two physiologically distinct segments. However, the detailed ultrastructure of this lens and precise optical role of each segment are far from clear. To …
View article: Evaluation of cataract formation in fish exposed to environmental radiation at Chernobyl and Fukushima
Evaluation of cataract formation in fish exposed to environmental radiation at Chernobyl and Fukushima Open
Recent studies apparently finding deleterious effects of radiation exposure on cataract formation in birds and voles living near Chernobyl represent a major challenge to current radiation protection regulations. This study conducted an int…
View article: Chondroitin Sulfate as a Potential Modulator of the Stem Cell Niche in Cornea
Chondroitin Sulfate as a Potential Modulator of the Stem Cell Niche in Cornea Open
Chondroitin sulfate (CS) is an important component of the extracellular matrix in multiple biological tissues. In cornea, the CS glycosaminoglycan (GAG) exists in hybrid form, whereby some of the repeating disaccharides are dermatan sulfat…
View article: Cell compaction is not required for the development of gradient refractive index profiles in the embryonic chick lens
Cell compaction is not required for the development of gradient refractive index profiles in the embryonic chick lens Open
The development of the eye requires the co-ordinated integration of optical and neural elements to create a system with requisite optics for the given animal. The eye lens has a lamellar structure with gradually varying protein concentrati…
View article: The eye lens: age-related trends and individual variations in refractive index and shape parameters
The eye lens: age-related trends and individual variations in refractive index and shape parameters Open
The eye lens grows throughout life by cell accrual on its surface and can change shape to adjust the focussing power of the eye. Varying concentrations of proteins in successive cell layers create a refractive index gradient. The continued…
View article: Refractive index degeneration in older lenses: A potential functional correlate to structural changes that underlie cataract formation
Refractive index degeneration in older lenses: A potential functional correlate to structural changes that underlie cataract formation Open
A major structure/function relationship in the eye lens is that between the constituent proteins, the crystallins and the optical property of refractive index. Structural breakdown that leads to cataract has been investigated in a number o…