Ju Young Lee
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View article: Ultra-processed food intake is associated with increased gastrointestinal tract symptoms and alterations in gut microbiota in patients with systemic sclerosis
Ultra-processed food intake is associated with increased gastrointestinal tract symptoms and alterations in gut microbiota in patients with systemic sclerosis Open
Background Alterations in the gastrointestinal (GI) microbiome (i.e., dysbiosis) are a feature of systemic sclerosis (SSc). Diet is a known modifier of the GI microbiome, and ultra-processed food (UPF) consumption has been associated with …
View article: Short-term and long-term effects of skin-to-skin contact in healthy term infants: study protocol for a parallel-group double-blind randomised controlled trial
Short-term and long-term effects of skin-to-skin contact in healthy term infants: study protocol for a parallel-group double-blind randomised controlled trial Open
Introduction Mother-infant skin-to-skin contact (SSC) improves developmental and cognitive outcomes in preterm infants. However, the effects of SSC on healthy term infants remain unclear. We aim to investigate the short-term and long-term …
View article: Assessing willingness to wear face masks to guide protection strategies in future pandemics
Assessing willingness to wear face masks to guide protection strategies in future pandemics Open
Background Face masks have been widely used to prevent disease transmission during outbreaks. In the United States, their use was initially limited due to cultural stigma and associations with criminal behavior. However, rising mortality r…
View article: Artificial intelligence-based digital pathology using H&E-stained whole slide images in immuno-oncology: from immune biomarker detection to immunotherapy response prediction
Artificial intelligence-based digital pathology using H&E-stained whole slide images in immuno-oncology: from immune biomarker detection to immunotherapy response prediction Open
Immuno-oncology and the advent of immunotherapies, in particular immune checkpoint inhibitors (ICIs), have fundamentally altered the way we treat cancer. Yet only a small subset of patients actually responds to ICIs, and many face signific…
View article: Neonatal Outcomes of the Intubation-Surfactant-Extubation versus Less Invasive Surfactant Administration Method: A National Cohort Study in Korea
Neonatal Outcomes of the Intubation-Surfactant-Extubation versus Less Invasive Surfactant Administration Method: A National Cohort Study in Korea Open
Introduction: This study aimed to compare the outcomes of intubation-surfactant-extubation (INSURE) and less invasive surfactant administration (LISA) in very preterm infants with respiratory distress syndrome. Methods: This study included…
View article: Horizontal gaze-evoked nystagmus in pontine gaze palsy: patterns and anatomical correlates
Horizontal gaze-evoked nystagmus in pontine gaze palsy: patterns and anatomical correlates Open
Background To delineate the patterns and anatomical correlates of gaze-evoked nystagmus (GEN) in horizontal gaze palsy due to dorsal pontine lesions. Methods A total of 17 patients with horizontal gaze palsy and unilateral dorsal pontine l…
View article: VLX600, an anticancer iron chelator, exerts antimicrobial effects on <i>Mycobacterium abscessus</i> infections
VLX600, an anticancer iron chelator, exerts antimicrobial effects on <i>Mycobacterium abscessus</i> infections Open
Mycobacterium abscessus presents significant clinical challenges due to its intrinsic and acquired resistance to antibiotics, resulting in prolonged treatments and poor patient outcomes. Addressing the urgent need for novel therapeutics, t…
View article: Corrigendum: Genomic analysis of carbapenem-resistant Klebsiella pneumoniae blood isolates from nationwide surveillance in South Korea
Corrigendum: Genomic analysis of carbapenem-resistant Klebsiella pneumoniae blood isolates from nationwide surveillance in South Korea Open
[This corrects the article DOI: 10.3389/fmicb.2025.1562222.].
View article: Genomic analysis of carbapenem-resistant Klebsiella pneumoniae blood isolates from nationwide surveillance in South Korea
Genomic analysis of carbapenem-resistant Klebsiella pneumoniae blood isolates from nationwide surveillance in South Korea Open
Introduction Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat to public health owing to its multidrug resistance and rapid dissemination. Methods This study analyzed CRKP isolates collected from bloodstream infe…
View article: Acoustofluidic bioassembly induced morphogenesis for therapeutic tissue fabrication
Acoustofluidic bioassembly induced morphogenesis for therapeutic tissue fabrication Open
View article: Perinatal Enterovirus Infection in Neonates: A Systematic Review
Perinatal Enterovirus Infection in Neonates: A Systematic Review Open
Enteroviruses (EVs) are a common cause of neonatal infections, and perinatal EV infection can lead to severe neonatal disease, including sepsis‐like presentations, and adverse pregnancy outcomes. However, a comprehensive understanding of t…
View article: HMG Box-containing Protein 1 (HBP1) Protects Against Pancreatic Injury in Acute Pancreatitis but Promotes Neoplastic Progression
HMG Box-containing Protein 1 (HBP1) Protects Against Pancreatic Injury in Acute Pancreatitis but Promotes Neoplastic Progression Open
HBP1 upregulation in pancreatitis mitigates pancreatic inflammatory injury; however, in the presence of oncogenic KRAS, it facilitates PanIN progression. Thus, HBP1 serves as a critical regulator in both pancreatitis and early pancreatic n…
View article: Author response: Accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis
Author response: Accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis Open
View article: Accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis
Accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis Open
An unprecedented amount of SARS-CoV-2 data has been accumulated compared with previous infectious diseases, enabling insights into its evolutionary process and more thorough analyses. This study investigates SARS-CoV-2 features as it evolv…
View article: AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis
AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis Open
An unprecedented amount of SARS-CoV-2 data has been accumulated compared with previous infectious diseases, enabling insights into its evolutionary process and more thorough analyses. This study investigates SARS-CoV-2 features as it evolv…
View article: Author response: AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis
Author response: AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis Open
View article: Towards Better Mental Health: Rapid Screening for Mood Disorder using Electroencephalogram and Facial Expression Paired Data with Weakly Supervised Contrastive Learning
Towards Better Mental Health: Rapid Screening for Mood Disorder using Electroencephalogram and Facial Expression Paired Data with Weakly Supervised Contrastive Learning Open
Depression has become a growing crisis among teenagers in recent years, with rates of suicide and depression rising annually. Despite the increasing need for more accessible resources to combat this mental health emergency, most available …
View article: AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis
AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis Open
This study presents an innovative research model utilizing big data science and protein structure prediction AI software. An unprecedented amount of SARS-CoV-2 data has been accumulated compared with previous infectious diseases, enabling …
View article: Accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis
Accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis Open
An unprecedented amount of SARS-CoV-2 data has been accumulated compared with previous infectious diseases, enabling insights into its evolutionary process and more thorough analyses. This study investigates SARS-CoV-2 features as it evolv…
View article: A Numerical Study on Endothermic Chemical Reactions of Supercritical n-dodecane in a Regenerative Cooling Channel of Hypersonic Vehicles
A Numerical Study on Endothermic Chemical Reactions of Supercritical n-dodecane in a Regenerative Cooling Channel of Hypersonic Vehicles Open
A numerical study has been conducted on the endothermic decomposition reactions of n-dodecane in a regenerative cooling channel by using a multi-step PPD (Proportional Product Distribution) model in order to develop a practical numerical s…
View article: Investigation of the efficacy and safety of wild- type and triple-gene knockout pig RBC transfusions in nonhuman primates
Investigation of the efficacy and safety of wild- type and triple-gene knockout pig RBC transfusions in nonhuman primates Open
Introduction Decreasing rates of blood donation and close margins between blood supply and demand pose challenges in healthcare. Genetically engineered pig red blood cells (pRBCs) have been explored as alternatives to human RBCs for transf…
View article: Clinical profile and treatment outcomes of idiopathic intracranial hypertension: a multicenter study from Korea
Clinical profile and treatment outcomes of idiopathic intracranial hypertension: a multicenter study from Korea Open
Background Currently, there is a relative lack of detailed reports regarding clinical presentation and outcome of idiopathic intracranial hypertension in Asians. This study aims to describe the clinical features and treatment outcomes of K…
View article: AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis
AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis Open
An unprecedented amount of SARS-CoV-2 data has been accumulated compared with previous infectious diseases, enabling insights into its evolutionary process and more thorough analyses. This study investigates SARS-CoV-2 features as it evolv…
View article: A Case Report of Alcohol-Associated Cirrhosis Treated with Cheongganhaeju-tang
A Case Report of Alcohol-Associated Cirrhosis Treated with Cheongganhaeju-tang Open
Objectives: This study identified the effects of Korean medicine treatment on a patient with alcohol-associated cirrhosis.Methods: A 50-year-old male with alcohol-associated cirrhosis was treated with Cheongganhaeju-tang from 10 November 2…
View article: #963 Discrepancy between actual and estimated urine creatinine excretion predicts mortality in chronic kidney disease: from the KNOW-CKD study
#963 Discrepancy between actual and estimated urine creatinine excretion predicts mortality in chronic kidney disease: from the KNOW-CKD study Open
Background and Aims Urine creatinine excretion is a surrogate marker of muscle mass and low urine creatinine excretion is a predictor of poor clinical outcome. There are several methods to estimate urine creatinine excretion. However, litt…
View article: WCN24-1782 THE IMPACT OF HIGHER PROTEIN PROVISION ON CONTINUOUS KIDNEY REPLACEMENT THERAPY
WCN24-1782 THE IMPACT OF HIGHER PROTEIN PROVISION ON CONTINUOUS KIDNEY REPLACEMENT THERAPY Open
Various nutrition guidelines recommend increased protein supplementation with continuous kidney replacement therapy (CKRT). Recent EFFORT Protein trial, international multicenter single-blinded randomized trial in the intensive care unit s…
View article: Efficacy of vestibular rehabilitation and its facilitating and hindering factors from real-world clinical data
Efficacy of vestibular rehabilitation and its facilitating and hindering factors from real-world clinical data Open
Background and purpose Customized vestibular rehabilitation improved dizziness and imbalance in several randomized controlled trials. In the present study, we determined the efficacy of customized vestibular rehabilitation using real-world…
View article: Oral administration of bone marrow-derived mesenchymal stem cells attenuates intestinal injury in necrotizing enterocolitis
Oral administration of bone marrow-derived mesenchymal stem cells attenuates intestinal injury in necrotizing enterocolitis Open
Background: Necrotizing enterocolitis (NEC) is a major cause of morbidity in premature infants. However, effective treatment options for NEC are currently lacking. Purpose: This study aimed to determine the optimal dose of intraperitoneall…
View article: Neurally adjusted ventilatory assist improves survival, and its early application accelerates weaning in preterm infants
Neurally adjusted ventilatory assist improves survival, and its early application accelerates weaning in preterm infants Open
Background Evidence to show that neurally adjusted ventilatory assist (NAVA) improves clinical outcomes is lacking. We aimed to analyze whether NAVA improves respiratory outcomes in preterm infants who require invasive mechanical ventilati…
View article: A Comparison Between <i>GalT</i><sup>−/−</sup>;<i>hCD39;hCD55</i> and <i>GalT</i><sup>−/−</sup>;<i>hCD39;hCD46;hCD55;TBM</i> Pig Kidneys Transplanted in Nonhuman Primates
A Comparison Between <i>GalT</i><sup>−/−</sup>;<i>hCD39;hCD55</i> and <i>GalT</i><sup>−/−</sup>;<i>hCD39;hCD46;hCD55;TBM</i> Pig Kidneys Transplanted in Nonhuman Primates Open
Because there is a shortage of donor kidneys, researchers are exploring the possibility of using genetically modified pig kidneys for transplantation. Approaches involving knockout of carbohydrate genes or knockin of protective proteins ha…