Anbarasu Kumarasamy
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View article: Tagging Fluorescent Reporter to Epinecidin-1 Antimicrobial Peptide
Tagging Fluorescent Reporter to Epinecidin-1 Antimicrobial Peptide Open
In this study, we successfully cloned the fluorescent proteins eGFP and DsRed in-frame with the antimicrobial peptide epinecidin-1 (FIFHIIKGLFHAGKMIHGLV) at the N-terminal. The cloning strategy involved inserting the fluorescent reporters …
View article: Synergistic Antimicrobial Activity of Epinecidin-1 and Ats Variants with Antibiotics Against Noso-Comial Pathogens: Implications for In Vivo Wound Healing
Synergistic Antimicrobial Activity of Epinecidin-1 and Ats Variants with Antibiotics Against Noso-Comial Pathogens: Implications for In Vivo Wound Healing Open
In this study, we investigated the antimicrobial properties of the antimicrobial peptide (AMP) epinecidin-1 and its variants against a range of nosocomial bacterial pathogens. The bacteriostatic effects on Escherichia coli, Haemophilus inf…
View article: Synergistic Antimicrobial Activity of Epinecidin-1 and Its Variants with Antibiotics Against Nosocomial Pathogens: Implications for In Vivo Wound Healing
Synergistic Antimicrobial Activity of Epinecidin-1 and Its Variants with Antibiotics Against Nosocomial Pathogens: Implications for In Vivo Wound Healing Open
In this study, we investigated the antimicrobial properties of the antimicrobial peptide (AMP) epinecidin-1 and its variants against a range of nosocomial bacterial pathogens. The bacteriostatic effects on Escherichia coli, Haemophilus inf…
View article: Tagging fluorescent reporter to epinecidin-1 antimicrobial peptide
Tagging fluorescent reporter to epinecidin-1 antimicrobial peptide Open
In this study, we successfully cloned the fluorescent proteins eGFP and DsRed in-frame with the antimicrobial peptide epinecidin-1 (FIFHIIKGLFHAGKMIHGLV). The cloning strategy involved inserting the fluorescent reporters into the expressio…
View article: Antibiofilm Activity of Protamine Against the Vaginal Candidiasis Isolates of Candida albicans, Candida tropicalis and Candida krusei
Antibiofilm Activity of Protamine Against the Vaginal Candidiasis Isolates of Candida albicans, Candida tropicalis and Candida krusei Open
Candida species, normally part of the healthy human flora, can cause severe opportunistic infections when their population increases. This risk is even greater in immunocompromised individuals. Women using intrauterine contraceptive device…
View article: Antibiofilm Activity of Epinecidin-1 and Its Variants Against Drug-Resistant Candida krusei and Candida tropicalis Isolates from Vaginal Candidiasis Patients
Antibiofilm Activity of Epinecidin-1 and Its Variants Against Drug-Resistant Candida krusei and Candida tropicalis Isolates from Vaginal Candidiasis Patients Open
Background/Objective: Indwelling intrauterine contraceptive devices (IUDs) have surfaces that facilitate the attachment of Candida spp., creating a suitable environment for biofilm formation. Due to this, vulvovaginal candidiasis (VVC) is …
View article: Antifungal activity of protamine
Antifungal activity of protamine Open
Background/Objective Antimicrobial peptides (AMPs) are important innate defense molecules having wide spectrum of bioactivities like antibacterial, antifungal, antiparasitic and antiviral activities. The primary role of AMPs is to exert cy…
View article: Anti-<i>Candida</i>and antibiofilm activity of epinecidin-1 and its variants
Anti-<i>Candida</i>and antibiofilm activity of epinecidin-1 and its variants Open
To boost the stability and antimicrobial efficacy of the antimicrobial peptide (AMP) epinecidin-1, we previously engineered two variants — variant-1 and variant-2—by substituting alanine and histidine residues with lysine. This modificatio…
View article: In silico and in vitro analysis of bioactive compounds extracted from Ocimum basilicum against vancomycin-resistant enterococci
In silico and in vitro analysis of bioactive compounds extracted from Ocimum basilicum against vancomycin-resistant enterococci Open
Ocimum basilicum is an important herbal medicinal plant that has not been previously investigated for its biological potential against multi-drug resistant (MDR) clinical pathogens. This study explored the efficiency of O. basilicum phytoc…
View article: Expression and purification of epinecidin-1 variant (Ac-Var-1) by acid cleavage
Expression and purification of epinecidin-1 variant (Ac-Var-1) by acid cleavage Open
View article: Antibiotic Susceptibility Patterns and Virulence-Associated Factors of Vancomycin-Resistant Enterococcal Isolates from Tertiary Care Hospitals
Antibiotic Susceptibility Patterns and Virulence-Associated Factors of Vancomycin-Resistant Enterococcal Isolates from Tertiary Care Hospitals Open
This study explored the prevalence of multi-drug resistance and virulence factors of enterococcal isolates obtained from various clinical specimens (n = 1575) including urine, blood, pus, tissue, catheter, vaginal wash, semen, and endotrac…
View article: Role of aquaporin 9 in hyperglycaemia-induced testicular leydig cell apoptosis
Role of aquaporin 9 in hyperglycaemia-induced testicular leydig cell apoptosis Open
Hyperglycaemia is an early symptom of diabetes mellitus (DM) and hyperglycaemia-induced apoptosis is the most widely accepted cause for diabetes induced male infertility/subfertility. Aquaporin (AQP) isoforms (AQP0-12), are water channels …
View article: Phenotypic Assessment of Probiotic and Bacteriocinogenic Efficacy of Indigenous LAB Strains from Human Breast Milk
Phenotypic Assessment of Probiotic and Bacteriocinogenic Efficacy of Indigenous LAB Strains from Human Breast Milk Open
Breast milk is the combination of bioactive compounds and microflora that promote newborn’s proper growth, gut flora, and immunity. Thus, it is always considered the perfect food for newborns. Amongst their bioactives, probiotic communitie…
View article: Outlooks of Nanotechnology in Organic Farming Management
Outlooks of Nanotechnology in Organic Farming Management Open
Technological advances are getting monitored with time, and science suggests nanotechnology as the emerging future. This even holds correct with human food consumption for health benefits, where organic farming is a better solution for the…
View article: Phenotypic assessment of safety and probiotic potential of native isolates from marine fish Moolgarda seheli towards sustainable aquaculture
Phenotypic assessment of safety and probiotic potential of native isolates from marine fish Moolgarda seheli towards sustainable aquaculture Open
View article: Construction of Genomic Library and Screening of Edwardsiella tarda Immunogenic Proteins for Their Protective Efficacy Against Edwardsiellosis
Construction of Genomic Library and Screening of Edwardsiella tarda Immunogenic Proteins for Their Protective Efficacy Against Edwardsiellosis Open
Edwardsiella tarda is a severe aquaculture pathogen that can infect many hosts including humans, animals, and fish. Timely diagnosis and treatment are crucial for the control of edwardsiellosis in the aqua industry. By using rabbit polyclo…
View article: Bioprocess optimization of PHB production utilizing agro (sago) waste as a sustainable substrate by the native isolate, Bacillus cereus
Bioprocess optimization of PHB production utilizing agro (sago) waste as a sustainable substrate by the native isolate, Bacillus cereus Open
Microbial synthesis of polyhydroxyalkanotes (PHA), the eco-friendly biopolymers are gaining more attention towards restricting the environmental pollution by substituting conventional non-biodegradable petroleum-based plastics. The current…
View article: Could aquaporin modulators be employed as prospective drugs for COVID-19 related pulmonary comorbidity?
Could aquaporin modulators be employed as prospective drugs for COVID-19 related pulmonary comorbidity? Open
View article: Retraction notice to “Peptide-induced formation of protein aggregates and amyloid fibrils in human and Guinea pig αA-crystallins under physiological conditions of temperature and pH” [Exp. Eye Res. 179 (2019) 193–205]
Retraction notice to “Peptide-induced formation of protein aggregates and amyloid fibrils in human and Guinea pig αA-crystallins under physiological conditions of temperature and pH” [Exp. Eye Res. 179 (2019) 193–205] Open
View article: Syntheses, physicochemical characterization, antibacterial studies on potassium morpholine dithiocarbamate nickel (II), copper (II) metal complexes and their ligands
Syntheses, physicochemical characterization, antibacterial studies on potassium morpholine dithiocarbamate nickel (II), copper (II) metal complexes and their ligands Open
View article: Hydrogen Sulfide Promotes Proliferation of HT-29 Colon Cancer Cells in a Mitochondria-independent Pathway
Hydrogen Sulfide Promotes Proliferation of HT-29 Colon Cancer Cells in a Mitochondria-independent Pathway Open
Several studies reported the carcinogenic and anticarcinogenic effects of hydrogen sulfide. The present study evaluated the role of mitochondria in mediating the anti/pro-carcinogenic effect of hydrogen sulfide on colon cancer cells as mit…
View article: RETRACTED: Peptide-induced formation of protein aggregates and amyloid fibrils in human and guinea pig αA-crystallins under physiological conditions of temperature and pH
RETRACTED: Peptide-induced formation of protein aggregates and amyloid fibrils in human and guinea pig αA-crystallins under physiological conditions of temperature and pH Open
View article: Production of biodiesel from dairy wastewater sludge: A laboratory and pilot scale study
Production of biodiesel from dairy wastewater sludge: A laboratory and pilot scale study Open
This study investigates the production of biodiesel from activated sludge of milk processing plant as a low cost feedstock. The method involves lipid extraction, refining and optimization of biodiesel from activated sludge under laboratory…