Chu Chen
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View article: Rivaroxaban in Chinese children with giant coronary artery aneurysms after Kawasaki disease
Rivaroxaban in Chinese children with giant coronary artery aneurysms after Kawasaki disease Open
The 15-mg-equivalent rivaroxaban regimen appeared feasible in Chinese children with GCAA after KD, with no GCAA thrombosis, major bleeding or CRNM bleeding observed within 6 months. Larger studies are required to confirm these preliminary …
View article: Alcohol consumption and upper aerodigestive tract squamous cell carcinoma: evidence from 28 prospective cohorts
Alcohol consumption and upper aerodigestive tract squamous cell carcinoma: evidence from 28 prospective cohorts Open
Background This study aimed to investigate the association between alcohol consumption and squamous cell cancers of the upper aerodigestive tract (UADT), using data from 28 cohorts within the Pooling Project of Prospective Studies of Diet …
View article: Cumulative handgrip strength and longitudinal changes in cognitive function and daily functioning among people aged 50 years and older: evidence from two longitudinal cohort studies
Cumulative handgrip strength and longitudinal changes in cognitive function and daily functioning among people aged 50 years and older: evidence from two longitudinal cohort studies Open
Our study suggested that lower levels of cumulative handgrip strength was related to an accelerated decline in cognitive function and daily functioning. Persistently strengthening muscle strength should be emphasized in preventing neurodeg…
View article: Predicted uniaxial compressive strength of fractured weakly cemented rock by LSSVM-NCV-ABKDE-based data-driven method
Predicted uniaxial compressive strength of fractured weakly cemented rock by LSSVM-NCV-ABKDE-based data-driven method Open
The evaluation of uniaxial compressive strength (UCS) for rock is a crucial factor in guaranteeing the safety of subterranean mining endeavours. The presence of cracks in the rock typically reduces its compressive strength, and these crack…
View article: Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America
Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America Open
Background Alcohol is a known carcinogen, yet the evidence for an association with pancreatic cancer risk is considered as limited or inconclusive by international expert panels. We examined the association between alcohol intake and pancr…
View article: Blind Restoration of High-Resolution Ultrasound Video
Blind Restoration of High-Resolution Ultrasound Video Open
Ultrasound imaging is widely applied in clinical practice, yet ultrasound videos often suffer from low signal-to-noise ratios (SNR) and limited resolutions, posing challenges for diagnosis and analysis. Variations in equipment and acquisit…
View article: DimGrow: Memory-Efficient Field-level Embedding Dimension Search
DimGrow: Memory-Efficient Field-level Embedding Dimension Search Open
Key feature fields need bigger embedding dimensionality, others need smaller. This demands automated dimension allocation. Existing approaches, such as pruning or Neural Architecture Search (NAS), require training a memory-intensive SuperN…
View article: Beyond the Tragedy of the Commons: Building A Reputation System for Generative Multi-agent Systems
Beyond the Tragedy of the Commons: Building A Reputation System for Generative Multi-agent Systems Open
The tragedy of the commons, where individual self-interest leads to collectively disastrous outcomes, is a pervasive challenge in human society. Recent studies have demonstrated that similar phenomena can arise in generative multi-agent sy…
View article: A Unified Model of Direct and Indirect Reciprocity in Multichannel Games
A Unified Model of Direct and Indirect Reciprocity in Multichannel Games Open
Reciprocity plays a crucial role in maintaining cooperation in human societies and AI systems. In this paper, we focus on reciprocity within multichannel games and examine how cooperation evolves in this context. We propose a unified frame…
View article: Plasma Insulin-like Growth Factor–Binding Protein-7 Is Positively Associated with Age, Obesity, Mortality, and Cancer in Postmenopausal Women
Plasma Insulin-like Growth Factor–Binding Protein-7 Is Positively Associated with Age, Obesity, Mortality, and Cancer in Postmenopausal Women Open
Background: Predictors of premature death and cancer development are needed to more precisely identify individuals who may warrant preventive intervention. Circulating insulin-like growth factor (IGF)–binding protein-7 (IGFBP7) and, to a l…
View article: Association between socioeconomic position and lung cancer incidence in 16 countries: a prospective cohort consortium study
Association between socioeconomic position and lung cancer incidence in 16 countries: a prospective cohort consortium study Open
This study was supported in part by the National Cancer Institute (NCI), the Lung Cancer Research Foundation (LCRF), and the World Cancer Research Fund (WCRF).
View article: Correction: Neuroprotective effect of Kaempferol Glycosides against brain injury and Neuroinflammation by inhibiting the activation of NF-κB and STAT3 in transient focal stroke
Correction: Neuroprotective effect of Kaempferol Glycosides against brain injury and Neuroinflammation by inhibiting the activation of NF-κB and STAT3 in transient focal stroke Open
[This corrects the article DOI: 10.1371/journal.pone.0055839.].
View article: Genetics of Recurrent Miscarriage and Pregnancy Loss in Women’s Reproductive Health
Genetics of Recurrent Miscarriage and Pregnancy Loss in Women’s Reproductive Health Open
Adverse pregnancy outcomes, such as sporadic and recurrent miscarriages and stillbirths, are significant medical concerns, impacting up to 15% of clinically recognised pregnancies. These outcomes are highly complex and multifactorial, with…
View article: P0190 Hypoglycemia induces SLC7A11-dependent disulfidptosis to regulate intestinal inflammation in IBD
P0190 Hypoglycemia induces SLC7A11-dependent disulfidptosis to regulate intestinal inflammation in IBD Open
Background IBD is an autoimmune disease related to intestinal mucosal immune dysregulation, and cellular metabolism is an important factor affecting intestinal immunity[1]. Previous studies have shown that the low-glucose environment inhib…
View article: Factors Associated with Potentially Preventable Hospitalizations for COPD Patients: A Qualitative Analysis of Patient Perspectives
Factors Associated with Potentially Preventable Hospitalizations for COPD Patients: A Qualitative Analysis of Patient Perspectives Open
Environmental characteristics and personal characteristics are factors associated with PPH for COPD patients. It is important to enhance the medical service ability, improve the accessibility of healthcare resources and the health literacy…
View article: High salt condition alters LPS synthesis and induces the emergence of drug resistance mutations in <i>Helicobacter pylori</i>
High salt condition alters LPS synthesis and induces the emergence of drug resistance mutations in <i>Helicobacter pylori</i> Open
The burgeoning emergence of drug-resistant Helicobacter pylori strains poses a significant challenge to the clinical success of eradication therapies and is primarily attributed to mutations within drug-targeting genes that lead to antibio…
View article: Continuous glucose monitoring versus conventional glucose monitoring in the ICU: A randomized controlled trial
Continuous glucose monitoring versus conventional glucose monitoring in the ICU: A randomized controlled trial Open
Compared with conventional POCM, CGMS did not decrease the 28-day mortality in critically ill participants with diabetes or stress-induced hyperglycemia. But CGMS may improve the glycemic control and may be increasingly used in critically …
View article: Effects of the COVID-19 Pandemic on the Number of New Dementia Diagnoses and the Quality of Dementia Diagnostics and Treatment
Effects of the COVID-19 Pandemic on the Number of New Dementia Diagnoses and the Quality of Dementia Diagnostics and Treatment Open
The quantity of new dementia registrations in SveDem decreased in the COVID-19 period and has not returned to pre-COVID-19 levels, but the quality of the work-ups which were conducted and registered in SveDem was similar or higher than in …
View article: Streaming Multi-agent Pathfinding
Streaming Multi-agent Pathfinding Open
The task of the multi-agent pathfinding (MAPF) problem is to navigate a team of agents from their start point to the goal points. However, this setup is unsuitable in the assembly line scenario, which is periodic with a long working hour. …